| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fernanda Hansen, Pablo Pandolfo, Fabiana Galland, Felipe Vasconcelos Torres, Márcio Ferreira Dutra, Cristiane Batassini, Maria Cristina Guerra, Marina Concli Leite, Carlos-Alberto Gonçalve. Methylglyoxal can mediate behavioral and neurochemical alterations in rat brain. Physiology & behavior. vol 164. issue Pt A. 2017-06-19. PMID:27235733. |
our biochemical findings support the hypothesis that mg induces persistent alterations in the hippocampus, but not in the cortex, related to glyoxalase 1 activity, ages content and glutamate uptake. |
2017-06-19 |
2023-08-13 |
rat |
| M Barbieri, A Ossato, I Canazza, C Trapella, A C Borelli, S Beggiato, C Rimondo, G Serpelloni, L Ferraro, M Mart. Synthetic cannabinoid JWH-018 and its halogenated derivatives JWH-018-Cl and JWH-018-Br impair Novel Object Recognition in mice: Behavioral, electrophysiological and neurochemical evidence. Neuropharmacology. vol 109. 2017-06-19. PMID:27346209. |
moreover, in vitro studies showed as jwh-018-r compounds negatively affected electrically evoked synaptic transmission, ltp and aminoacid (glutamate and gaba) release in hippocampal slices. |
2017-06-19 |
2023-08-13 |
mouse |
| Lijuan Jiao, Yaxin Li, Yanqing Zhang, Junjun Liu, Junbo Xie, Kunsheng Zhang, Aimin Zho. Degradation Kinetics of 6‴-p-Coumaroylspinosin and Identification of Its Metabolites by Rat Intestinal Flora. Journal of agricultural and food chemistry. vol 65. issue 22. 2017-06-19. PMID:28513155. |
spinosin and swertisin could improve mrna transcription levels of glutamate receptor k1, k2, and k3 (gluk1, gluk2, and gluk3) subunits in rat hippocampal neurons. |
2017-06-19 |
2023-08-13 |
rat |
| Thomas M Sanderson, Ellen L Hogg, Graham L Collingridge, Sonia A L Corrê. Hippocampal metabotropic glutamate receptor long-term depression in health and disease: focus on mitogen-activated protein kinase pathways. Journal of neurochemistry. vol 139 Suppl 2. 2017-06-15. PMID:26923875. |
hippocampal metabotropic glutamate receptor long-term depression in health and disease: focus on mitogen-activated protein kinase pathways. |
2017-06-15 |
2023-08-13 |
Not clear |
| Sukumaran Muralidharan, Nathaniel D A Dirda, Elizabeth J Katz, Cha-Min Tang, Sharba Bandyopadhyay, Patrick O Kanold, Joseph P Y Ka. Ncm, a Photolabile Group for Preparation of Caged Molecules: Synthesis and Biological Application. PloS one. vol 11. issue 10. 2017-06-15. PMID:27695074. |
the utility of ncm-caged glutamate for neuronal photostimulation is demonstrated in cultured hippocampal neurons and in brain slice preparations. |
2017-06-15 |
2023-08-13 |
Not clear |
| Alexander W M Hooper, Javier F Alamilla, Rosemarie E Venier, Deda C Gillespie, Suleiman A Igdour. Neuronal pentraxin 1 depletion delays neurodegeneration and extends life in Sandhoff disease mice. Human molecular genetics. vol 26. issue 4. 2017-06-12. PMID:28007910. |
sandhoff mouse brain slices reveals a reduction in ampa receptor-mediated currents, and increased variability in total glutamate currents in the ca1 region of the hippocampus; np1-/-hexb-/- mice show a correction of this phenotype, suggesting np1-38 may be interfering with glutamate receptor function. |
2017-06-12 |
2023-08-13 |
mouse |
| Franziska Altmüller, Santosh Pothula, Anil Annamneedi, Saeideh Nakhaei-Rad, Carolina Montenegro-Venegas, Eneko Pina-Fernández, Claudia Marini, Monica Santos, Denny Schanze, Dirk Montag, Mohammad R Ahmadian, Oliver Stork, Martin Zenker, Anna Fejtov. Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy. PLoS genetics. vol 13. issue 3. 2017-06-07. PMID:28346493. |
we observed an altered surface expression and trafficking of synaptic glutamate receptors, which are crucial for hippocampal neuronal plasticity. |
2017-06-07 |
2023-08-13 |
mouse |
| Marta Gómez-Galán, Teresa Femenía, Elin Åberg, Lisette Graae, Ann Van Eeckhaut, Ilse Smolders, Stefan Brené, Maria Lindsko. Running Opposes the Effects of Social Isolation on Synaptic Plasticity and Transmission in a Rat Model of Depression. PloS one. vol 11. issue 10. 2017-06-05. PMID:27764188. |
these functional synaptic alterations co-exist with changes in hippocampal protein expression levels: social isolation in fsl rats reduce expression of the glial glutamate transporter glt-1, and increase expression of the glua2 ampa-receptor subunit. |
2017-06-05 |
2023-08-13 |
rat |
| Marianna E Jung, Daniel B Metzger, Hriday K Da. The Role of Presenilin-1 in the Excitotoxicity of Ethanol Withdrawal. The Journal of pharmacology and experimental therapeutics. vol 358. issue 3. 2017-05-26. PMID:27278235. |
additionally, we used ethanol-withdrawn ht22 cells (mouse hippocampal) treated with the inhibitor of glutamate receptors [dizocilpine (mk-801)], p38α (sb203580; 4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1h-imidazol-5-yl]pyridine), or γ-secretase [n-[n- (3,5-difluorophenacetyl)-l-alanyl]-s-phenylglycine t-butyl ester (dapt)] during ew. |
2017-05-26 |
2023-08-13 |
mouse |
| Haining Yu, Tao Chen, Li Zhou, Jiyou Tan. Effect of Selective 5-HT6R Agonist on Expression of 5-HT Receptor and Neurotransmitter in Vascular Dementia Rats. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2017-05-25. PMID:28196966. |
brains were extracted to separate the cortex and hippocampal tissues, in which glutamate and g-aminobutyric acid (gaba) levels were analyzed. |
2017-05-25 |
2023-08-13 |
rat |
| Yanlei Wang, Mo Chen, Yinghua Zhang, Taoguang Huo, Ying Fang, Xuexin Jiao, Mingmei Yuan, Hong Jian. Effects of realgar on GSH synthesis in the mouse hippocampus: Involvement of system XAG(-), system XC(-), MRP-1 and Nrf2. Toxicology and applied pharmacology. vol 308. 2017-05-23. PMID:27412851. |
here, we used mouse models of exposure to realgar to show that realgar affects the synthesis of gsh in the hippocampus, leading to ultrastructural changes in hippocampal neurons and synapses and deficiencies in cognitive abilities, and that the mechanisms that cause this effect may be associated with alterations in the expression of system xag(-), system xc(-), multidrug resistance-associated protein 1(mrp-1), nuclear factor e2-related factor 2 (nrf2), γ-glutamylcysteine synthetase (γ-gcs), and the levels of glutamate (glu) and cysteine (cys) in the extracellular fluid. |
2017-05-23 |
2023-08-13 |
mouse |
| Keiko Matsud. Synapse organization and modulation via C1q family proteins and their receptors in the central nervous system. Neuroscience research. vol 116. 2017-05-18. PMID:27845167. |
especially at mossy fiber (mf)-ca3 synapses in the hippocampus, postsynaptic kainate-type glutamate receptors (kars) are involved in synaptic network activity through their characteristic channel kinetics. |
2017-05-18 |
2023-08-13 |
Not clear |
| Noha F Abdelkader, Muhammed A Saad, Rania M Abdelsala. Neuroprotective effect of nebivolol against cisplatin-associated depressive-like behavior in rats. Journal of neurochemistry. vol 141. issue 3. 2017-05-02. PMID:28178754. |
in parallel, cisplatin administration prominently reduced gaba and elevated glutamate levels in the cortical and hippocampal tissues. |
2017-05-02 |
2023-08-13 |
rat |
| Holly C Hunsberger, Gregory W Konat, Miranda N Ree. Peripheral viral challenge elevates extracellular glutamate in the hippocampus leading to seizure hypersusceptibility. Journal of neurochemistry. vol 141. issue 3. 2017-05-02. PMID:28244106. |
peripheral viral challenge elevates extracellular glutamate in the hippocampus leading to seizure hypersusceptibility. |
2017-05-02 |
2023-08-13 |
mouse |
| Holly C Hunsberger, Gregory W Konat, Miranda N Ree. Peripheral viral challenge elevates extracellular glutamate in the hippocampus leading to seizure hypersusceptibility. Journal of neurochemistry. vol 141. issue 3. 2017-05-02. PMID:28244106. |
we have further demonstrated that pic challenge robustly increases the level of tonic extracellular glutamate and neuronal excitability in the hippocampus. |
2017-05-02 |
2023-08-13 |
mouse |
| Pratyush S Suryavanshi, Subhash C Gupta, Roopali Yadav, Varun Kesherwani, Jinxu Liu, Shashank M Dravi. Glutamate Delta-1 Receptor Regulates Metabotropic Glutamate Receptor 5 Signaling in the Hippocampus. Molecular pharmacology. vol 90. issue 2. 2017-05-01. PMID:27231330. |
glutamate delta-1 receptor regulates metabotropic glutamate receptor 5 signaling in the hippocampus. |
2017-05-01 |
2023-08-13 |
mouse |
| Pratyush S Suryavanshi, Subhash C Gupta, Roopali Yadav, Varun Kesherwani, Jinxu Liu, Shashank M Dravi. Glutamate Delta-1 Receptor Regulates Metabotropic Glutamate Receptor 5 Signaling in the Hippocampus. Molecular pharmacology. vol 90. issue 2. 2017-05-01. PMID:27231330. |
here, we identified a novel role of glud1 in regulating metabotropic glutamate receptor 5 (mglu5) signaling in the hippocampus. |
2017-05-01 |
2023-08-13 |
mouse |
| Hong-Chun Li, Jie Xiao, Yi-Long Huang, Long-Jun Li, Hong Jiang, Li-Xuan Huang, Ting Yang, Ling Yang, Fan L. [Reduction in hypoxia-derived neuroinflammation and dysfunctional glutamate transporters by minocycline may restore hypoxia-injured cognition of neonatal rat]. Sheng li xue bao : [Acta physiologica Sinica]. vol 68. issue 2. 2017-04-28. PMID:27108901. |
inflammatory mediators (iba-1, il-1β, tnf-α and tgf-β1), glutamate transporters (eaat1 and eaat2), total tau and phosphorylated tau (phosphorylation sites: tyr18, thr205, thr231, ser396 and ser404) protein expressions in the hippocampus were detected by western blot 7 d after hypoxic exposure. |
2017-04-28 |
2023-08-13 |
rat |
| Keiko Kanamor. Faster flux of neurotransmitter glutamate during seizure - Evidence from 13C-enrichment of extracellular glutamate in kainate rat model. PloS one. vol 12. issue 4. 2017-04-27. PMID:28403176. |
for the first time in vivo, this study examined the effects of epileptic seizures on fluxes of the neurotransmitter glutamate and its precursor glutamine in the extracellular fluid of the hippocampus. |
2017-04-27 |
2023-08-13 |
rat |
| Martin J Brodie, Frank Besag, Alan B Ettinger, Marco Mula, Gabriella Gobbi, Stefano Comai, Albert P Aldenkamp, Bernhard J Steinhof. Epilepsy, Antiepileptic Drugs, and Aggression: An Evidence-Based Review. Pharmacological reviews. vol 68. issue 3. 2017-04-20. PMID:27255267. |
we review the common neurotransmitter systems and brain regions implicated in both epilepsy and aggression, including the gaba, glutamate, serotonin, dopamine, and noradrenaline systems and the hippocampus, amygdala, prefrontal cortex, anterior cingulate cortex, and temporal lobes. |
2017-04-20 |
2023-08-13 |
Not clear |