| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Suzan Gonçalves Rosa, Caroline Brandão Quines, Eluza Curte Stangherlin, Cristina Wayne Nogueir. Diphenyl diselenide ameliorates monosodium glutamate induced anxiety-like behavior in rats by modulating hippocampal BDNF-Akt pathway and uptake of GABA and serotonin neurotransmitters. Physiology & behavior. vol 155. 2016-10-17. PMID:26657020. |
diphenyl diselenide ameliorates monosodium glutamate induced anxiety-like behavior in rats by modulating hippocampal bdnf-akt pathway and uptake of gaba and serotonin neurotransmitters. |
2016-10-17 |
2023-08-13 |
rat |
| Yi Chang, Tzu Yu Lin, Cheng Wei Lu, Shu Kuei Huang, Ying Chou Wang, Su Jane Wan. Xanthohumol-induced presynaptic reduction of glutamate release in the rat hippocampus. Food & function. vol 7. issue 1. 2016-10-17. PMID:26667007. |
xanthohumol-induced presynaptic reduction of glutamate release in the rat hippocampus. |
2016-10-17 |
2023-08-13 |
rat |
| Yi Chang, Tzu Yu Lin, Cheng Wei Lu, Shu Kuei Huang, Ying Chou Wang, Su Jane Wan. Xanthohumol-induced presynaptic reduction of glutamate release in the rat hippocampus. Food & function. vol 7. issue 1. 2016-10-17. PMID:26667007. |
this study examined whether xanthohumol, a hop-derived prenylated flavonoid present in beer, affects glutamate release in the rat hippocampus. |
2016-10-17 |
2023-08-13 |
rat |
| Yi Chang, Tzu Yu Lin, Cheng Wei Lu, Shu Kuei Huang, Ying Chou Wang, Su Jane Wan. Xanthohumol-induced presynaptic reduction of glutamate release in the rat hippocampus. Food & function. vol 7. issue 1. 2016-10-17. PMID:26667007. |
in the rat hippocampal nerve terminals (synaptosomes), xanthohumol inhibited the release of 4-aminopyridine (4-ap)-evoked glutamate and the elevation of cytosolic ca(2+) concentration, whereas it had no effect on 4-ap-mediated depolarization. |
2016-10-17 |
2023-08-13 |
rat |
| Yi Chang, Tzu Yu Lin, Cheng Wei Lu, Shu Kuei Huang, Ying Chou Wang, Su Jane Wan. Xanthohumol-induced presynaptic reduction of glutamate release in the rat hippocampus. Food & function. vol 7. issue 1. 2016-10-17. PMID:26667007. |
in addition, immunocytochemical data demonstrated that gabaa receptors are present in the hippocampal synaptosomes and that the xanthohumol effect on evoked glutamate release was antagonized by the gabaa receptor antagonist sr95531. |
2016-10-17 |
2023-08-13 |
rat |
| Yi Chang, Tzu Yu Lin, Cheng Wei Lu, Shu Kuei Huang, Ying Chou Wang, Su Jane Wan. Xanthohumol-induced presynaptic reduction of glutamate release in the rat hippocampus. Food & function. vol 7. issue 1. 2016-10-17. PMID:26667007. |
we conclude that xanthohumol acts at gabaa receptors present in the hippocampal nerve terminals to decrease the ca(2+) influx through n- and p/q-type ca(2+) channels, which subsequently suppresses the ca(2+)-calmodulin/pka cascade to decrease the evoked glutamate release. |
2016-10-17 |
2023-08-13 |
rat |
| Alida Spalloni, Patrizia Longon. Cognitive impairment in amyotrophic lateral sclerosis, clues from the SOD1 mouse. Neuroscience and biobehavioral reviews. vol 60. 2016-10-14. PMID:26602023. |
the present review aims at providing an overview of the data obtained with the sod1 animal models first and foremost on the cortical and subcortical regions, the cortico-striatal and hippocampal synaptic plasticity, dendritic branching and glutamate receptors function. |
2016-10-14 |
2023-08-13 |
mouse |
| Nicolas Toni, Alejandro F Schinde. Maturation and Functional Integration of New Granule Cells into the Adult Hippocampus. Cold Spring Harbor perspectives in biology. vol 8. issue 1. 2016-10-13. PMID:26637288. |
the adult hippocampus generates functional dentate granule cells (gcs) that release glutamate onto target cells in the hilus and cornus ammonis (ca)3 region, and receive glutamatergic and γ-aminobutyric acid (gaba)ergic inputs that tightly control their spiking activity. |
2016-10-13 |
2023-08-13 |
Not clear |
| R A Mohamed, A M Agha, A A Abdel-Rahman, N N Nassa. Role of adenosine A2A receptor in cerebral ischemia reperfusion injury: Signaling to phosphorylated extracellular signal-regulated protein kinase (pERK1/2). Neuroscience. vol 314. 2016-10-13. PMID:26642806. |
consequent to perk1/2 inhibition, reduced hippocampal microglial activation, glial tumor necrosis factor-alpha (tnf-α) and brain-derived neurotropic factor (bdnf) expression, glutamate (glu), inducible nitric oxide synthase (inos) and thiobarbituric acid reactive substances (tbars) were evident in animals receiving sch58261. |
2016-10-13 |
2023-08-13 |
rat |
| Edward D Levi. Learning about cognition risk with the radial-arm maze in the developmental neurotoxicology battery. Neurotoxicology and teratology. vol 52. issue Pt A. 2016-10-12. PMID:26013674. |
these systems, notably the hippocampus and frontal cortex, and acetylcholine and glutamate neurotransmitter systems, are the same neural systems that have been shown in humans to be critical for learning and memory. |
2016-10-12 |
2023-08-13 |
mouse |
| Tomas Fanutza, Dolores Del Prete, Michael J Ford, Pablo E Castillo, Luciano D'Adami. APP and APLP2 interact with the synaptic release machinery and facilitate transmitter release at hippocampal synapses. eLife. vol 4. 2016-10-11. PMID:26551565. |
jcasp interferes with the app-presynaptic proteins interaction and, if linked to a cell-penetrating peptide, reduces glutamate release in acute hippocampal slices from wild-type but not app deficient mice, indicating that jcasp inhibits app function.the app-like protein-2 (aplp2) also binds the synaptic release machinery. |
2016-10-11 |
2023-08-13 |
mouse |
| Pan-Yue Deng, Vitaly A Klyachk. Genetic upregulation of BK channel activity normalizes multiple synaptic and circuit defects in a mouse model of fragile X syndrome. The Journal of physiology. vol 594. issue 1. 2016-10-05. PMID:26427907. |
genetic upregulation of bk channel activity via deletion of bkβ4 normalized action potential duration, excessive glutamate release and short-term synaptic plasticity during naturalistic stimulus trains in excitatory hippocampal neurons in the absence of fmrp. |
2016-10-05 |
2023-08-13 |
mouse |
| Pan-Yue Deng, Vitaly A Klyachk. Genetic upregulation of BK channel activity normalizes multiple synaptic and circuit defects in a mouse model of fragile X syndrome. The Journal of physiology. vol 594. issue 1. 2016-10-05. PMID:26427907. |
among these presynaptic fmrp functions, fmrp interaction with large-conductance calcium-activated k(+) (bk) channels, specifically their auxiliary β4 subunit, regulates action potential waveform and glutamate release in hippocampal and cortical pyramidal neurons. |
2016-10-05 |
2023-08-13 |
mouse |
| Vicente Hernández-Rabaza, Andrea Cabrera-Pastor, Lucas Taoro-González, Michele Malaguarnera, Ana Agustí, Marta Llansola, Vicente Felip. Hyperammonemia induces glial activation, neuroinflammation and alters neurotransmitter receptors in hippocampus, impairing spatial learning: reversal by sulforaphane. Journal of neuroinflammation. vol 13. 2016-10-05. PMID:26883214. |
two main aims of this work were: (1) to assess whether chronic hyperammonemia increases inflammatory factors in the hippocampus and if this is associated with microglia and/or astrocytes activation and (2) to assess whether hyperammonemia-induced neuroinflammation in the hippocampus is associated with altered membrane expression of glutamate and gaba receptors and spatial learning impairment. |
2016-10-05 |
2023-08-13 |
rat |
| S Santarelli, K V Wagner, C Labermaier, A Uribe, C Dournes, G Balsevich, J Hartmann, M Masana, F Holsboer, A Chen, M B Müller, M V Schmid. SLC6A15, a novel stress vulnerability candidate, modulates anxiety and depressive-like behavior: involvement of the glutamatergic system. Stress (Amsterdam, Netherlands). vol 19. issue 1. 2016-09-22. PMID:26585320. |
risk allele carriers for a single nucleotide polymorphism (snp) in a slc6a15 regulatory region display altered hippocampal volume, glutamate levels, and hypothalamus-pituitary-adrenal axis activity, all markers associated with major depression. |
2016-09-22 |
2023-08-13 |
mouse |
| Yun Wang, Javed Iqbal, Yahui Liu, Rui Su, Song Lu, Guang Peng, Yongqian Zhang, Hong Qing, Yulin Den. Effects of simulated microgravity on the expression of presynaptic proteins distorting the GABA/glutamate equilibrium--A proteomics approach. Proteomics. vol 15. issue 22. 2016-09-21. PMID:26359799. |
sm decreased the content of γ-aminobutyric acid (gaba) and increased the content of glutamate (glu) in the rat hippocampus. |
2016-09-21 |
2023-08-13 |
rat |
| Ming Lei, Huixin Xu, Zhangyuan Li, Zemin Wang, Tiernan T O'Malley, Dainan Zhang, Dominic M Walsh, Pingyi Xu, Dennis J Selkoe, Shaomin L. Soluble Aβ oligomers impair hippocampal LTP by disrupting glutamatergic/GABAergic balance. Neurobiology of disease. vol 85. 2016-09-21. PMID:26525100. |
soluble aβ oligomers (oaβ) blocked hippocampal ltp and epsp-spike (e-s) potentiation, and these effects were occluded by prior treatment with the glutamate uptake inhibitor tboa. |
2016-09-21 |
2023-08-13 |
mouse |
| Ming Lei, Huixin Xu, Zhangyuan Li, Zemin Wang, Tiernan T O'Malley, Dainan Zhang, Dominic M Walsh, Pingyi Xu, Dennis J Selkoe, Shaomin L. Soluble Aβ oligomers impair hippocampal LTP by disrupting glutamatergic/GABAergic balance. Neurobiology of disease. vol 85. 2016-09-21. PMID:26525100. |
in accord, oaβ elevated glutamate levels in the hippocampal slice medium. |
2016-09-21 |
2023-08-13 |
mouse |
| Rafael M Bitencourt, Alán Alpár, Valentina Cinquina, Samira G Ferreira, Bárbara S Pinheiro, Cristina Lemos, Catherine Ledent, Reinaldo N Takahashi, Fernando J Sialana, Gert Lubec, Rodrigo A Cunha, Tibor Harkany, Attila Köfalv. Lack of presynaptic interaction between glucocorticoid and CB1 cannabinoid receptors in GABA- and glutamatergic terminals in the frontal cortex of laboratory rodents. Neurochemistry international. vol 90. 2016-09-20. PMID:26196379. |
additional confocal microscopy analysis of cortical and hippocampal regions revealed vesicular gaba transporter-positive and vesicular glutamate transporter 1-positive nerve terminals endowed with cb1r immunoreactivity, apposing gcr-positive post-synaptic compartments. |
2016-09-20 |
2023-08-13 |
mouse |
| Zsolt Bagosi, Beáta Balangó, Dávid Pintér, Krisztina Csabafi, Miklós Jászberényi, Gyula Szabó, Gyula Telegd. The effects of CRF and urocortins on the hippocampal glutamate release. Neurochemistry international. vol 90. 2016-09-20. PMID:26216727. |
the effects of crf and urocortins on the hippocampal glutamate release. |
2016-09-20 |
2023-08-13 |
rat |