| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L P Voytenko, I V Lushnikova, A V Savotchenko, E V Isaeva, M V Skok, O Yu Lykhmus, M A Patseva, G G Skib. Hippocampal GABAergic interneurons coexpressing alpha7-nicotinic receptors and connexin-36 are able to improve neuronal viability under oxygen-glucose deprivation. Brain research. vol 1616. 2016-03-02. PMID:25966616. |
we hypothesized that hippocampal ischemia-resistant gabaergic interneurons coexpressing glutamate decarboxylase-67 isoform (gad67(+)), α7nachrs(+), cx36(+) are able to enhance neuronal viability. |
2016-03-02 |
2023-08-13 |
rat |
| Dominik Strzelecki, Michał Podgórski, Olga Kałużyńska, Oliwia Gawlik-Kotelnicka, Ludomir Stefańczyk, Magdalena Kotlicka-Antczak, Agnieszka Gmitrowicz, Piotr Grzela. Supplementation of antipsychotic treatment with sarcosine – GlyT1 inhibitor – causes changes of glutamatergic (1)NMR spectroscopy parameters in the left hippocampus in patients with stable schizophrenia. Neuroscience letters. vol 606. 2016-03-01. PMID:26306650. |
in the sarcosine group, after 6-month treatment, we found significant decrease in hippocampal glx/cr (glx-complex of glutamate, glutamine and gaba, cr-creatine) and glx/cho (cho-choline), while n-acetylaspartate (naa), myo-inositol (mi), cr and cho parameters remained stable along the study and also did not differ significantly between both groups. |
2016-03-01 |
2023-08-13 |
Not clear |
| Helene A Fachim, Adriana C Pereira, Melina M Iyomasa-Pilon, Maria L N M Ros. Differential Expression of AMPA Subunits Induced by NMDA Intrahippocampal Injection in Rats. Frontiers in neuroscience. vol 10. 2016-02-25. PMID:26912994. |
the aim of this work was to study the time course of changes in the expression of glur1 and glur2 subunits of glutamate amino-acid-3-hydroxy-5-methyl-isoxazol-4-propionic acid (ampa) receptors in rat hippocampus induced by nmda intrahippocampal injection. |
2016-02-25 |
2023-08-13 |
rat |
| Mansour A Al-Hazmi, Sayed M Rawi, Nadia Ms Arafa, Abeer Wagas, Ayat Os Montasse. The potent effects of ginseng root extract and memantine on cognitive dysfunction in male albino rats. Toxicology and industrial health. vol 31. issue 6. 2016-02-18. PMID:23406953. |
scopolamine (2 mg/kg ip) group showed significant increase in ache reactivity and glutamate level and reduced monoamines (norepinephrine, dopamine and serotonin) and γ-aminobutyric acid contents in cortex, hippocampus and striatum. |
2016-02-18 |
2023-08-12 |
rat |
| Wagner C Martins, Vanessa Valgas dos Santos, Alessandra Antunes dos Santos, Samuel Vandresen-Filho, Tharine A Dal-Cim, Karen A de Oliveira, Claudia B N Mendes-de-Aguiar, Marcelo Farina, Rui Daniel Prediger, Giordano Gubert Viola, Carla I Tasc. Atorvastatin Prevents Cognitive Deficits Induced by Intracerebroventricular Amyloid-β1-40 Administration in Mice: Involvement of Glutamatergic and Antioxidant Systems. Neurotoxicity research. vol 28. issue 1. 2016-02-17. PMID:25827781. |
ex vivo evaluation of glutamate uptake into hippocampal and cerebral cortices slices showed atorvastatin, and aβ1-40 decreased hippocampal and cortical na(+)-dependent glutamate uptake. |
2016-02-17 |
2023-08-13 |
mouse |
| Daniel F Hermens, Sharon L Naismith, Kate M Chitty, Rico S C Lee, Ashleigh Tickell, Shantel L Duffy, Casey Paquola, Django White, Ian B Hickie, Jim Lagopoulo. Cluster analysis reveals abnormal hippocampal neurometabolic profiles in young people with mood disorders. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 25. issue 6. 2016-02-16. PMID:25795519. |
the ratios (relative to creatine) of glutamate (glu), n-acetyl aspartate (naa) and myo-inositol (mi) measured within the hippocampus. |
2016-02-16 |
2023-08-13 |
human |
| Katarzyna Młyniec, Magdalena Gaweł, Tadeusz Librowski, Witold Reczyński, Beata Bystrowska, Birgitte Hols. Investigation of the GPR39 zinc receptor following inhibition of monoaminergic neurotransmission and potentialization of glutamatergic neurotransmission. Brain research bulletin. vol 115. 2016-02-16. PMID:25917396. |
additionally, we investigated tryptophan, tyrosine and glutamate concentrations in the hippocampus and frontal cortex of gpr39 knockout (gpr39 ko) mice. |
2016-02-16 |
2023-08-13 |
mouse |
| Katarzyna Młyniec, Magdalena Gaweł, Tadeusz Librowski, Witold Reczyński, Beata Bystrowska, Birgitte Hols. Investigation of the GPR39 zinc receptor following inhibition of monoaminergic neurotransmission and potentialization of glutamatergic neurotransmission. Brain research bulletin. vol 115. 2016-02-16. PMID:25917396. |
liquid chromatography-mass spectrometry (lc-ms) showed a significant decrease in tryptophan and tyrosine, but not in glutamate concentrations in the hippocampus of gpr39 ko mice. |
2016-02-16 |
2023-08-13 |
mouse |
| Hui Zhang, Mingming Huang, Lifeng Gao, Hao Le. Region-specific cerebral metabolic alterations in streptozotocin-induced type 1 diabetic rats: an in vivo proton magnetic resonance spectroscopy study. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 35. issue 11. 2016-02-16. PMID:26036938. |
the diabetic visual cortex had more or less normal-appearing metabolic profile; while the striatum and hippocampus showed similar abnormalities in neuronal metabolism involving n-acetyl aspartate and glutamate; but only the hippocampus exhibited significant changes in glial markers such as taurine and myo-inositol. |
2016-02-16 |
2023-08-13 |
rat |
| Michael D Roger. Commentary on "Monosodium glutamate neurotoxicity increases beta amyloid in the rat hippocampus: A potential role for cyclic AMP protein kinase" (Dief et al., 2014). Neurotoxicology. vol 50. 2016-02-16. PMID:26099246. |
commentary on "monosodium glutamate neurotoxicity increases beta amyloid in the rat hippocampus: a potential role for cyclic amp protein kinase" (dief et al., 2014). |
2016-02-16 |
2023-08-13 |
rat |
| Roberta Imperatore, Giovanna Morello, Livio Luongo, Ulrike Taschler, Rosaria Romano, Danilo De Gregorio, Carmela Belardo, Sabatino Maione, Vincenzo Di Marzo, Luigia Cristin. Genetic deletion of monoacylglycerol lipase leads to impaired cannabinoid receptor CB₁R signaling and anxiety-like behavior. Journal of neurochemistry. vol 135. issue 4. 2016-02-16. PMID:26223500. |
we found a widespread cb1 r/β-arrestin2 co-expression in the mpfc, amygdala and hippocampus accompanied by impairment of extracellular signal-regulated kinase signaling and elevation of vesicular glutamate transporter (vglut1) at cb1 r-positive excitatory terminals in the mpfc, or vesicular gaba transporter (vgat) at cb1 r-positive inhibitory terminals in the amygdala and hippocampus. |
2016-02-16 |
2023-08-13 |
mouse |
| Konstantinos Sarantis, Eirini Tsiamaki, Stylianos Kouvaros, Costas Papatheodoropoulos, Fevronia Angelato. Adenosine A₂A receptors permit mGluR5-evoked tyrosine phosphorylation of NR2B (Tyr1472) in rat hippocampus: a possible key mechanism in NMDA receptor modulation. Journal of neurochemistry. vol 135. issue 4. 2016-02-16. PMID:26303340. |
we propose the following molecular mechanism by which metabotropic glutamate receptor 5 (mglur5) potentiate ionotropic glutamate n-methyl-d-aspartate receptor (nmdar) responses in rat hippocampus. |
2016-02-16 |
2023-08-13 |
rat |
| Tao-guang Huo, Wei-kai Li, Ying-hua Zhang, Jie Yuan, Lan-yue Gao, Yuan Yuan, Hui-lei Yang, Hong Jiang, Gui-fan Su. Excitotoxicity Induced by Realgar in the Rat Hippocampus: the Involvement of Learning Memory Injury, Dysfunction of Glutamate Metabolism and NMDA Receptors. Molecular neurobiology. vol 51. issue 3. 2016-02-12. PMID:24865513. |
excitotoxicity induced by realgar in the rat hippocampus: the involvement of learning memory injury, dysfunction of glutamate metabolism and nmda receptors. |
2016-02-12 |
2023-08-13 |
rat |
| Tao-guang Huo, Wei-kai Li, Ying-hua Zhang, Jie Yuan, Lan-yue Gao, Yuan Yuan, Hui-lei Yang, Hong Jiang, Gui-fan Su. Excitotoxicity Induced by Realgar in the Rat Hippocampus: the Involvement of Learning Memory Injury, Dysfunction of Glutamate Metabolism and NMDA Receptors. Molecular neurobiology. vol 51. issue 3. 2016-02-12. PMID:24865513. |
the levels of glutamate (glu) and glutamine (gln) in the hippocampus and hippocampal ca1 region; the activities of glutamine synthetase (gs) and phosphate-activated glutaminase (pag); the mrna and protein expression of glutamate transporter 1 (glt-1), glutamate/aspartate transporter (glast), and n-methyl-d-aspartate (nmda) receptors; and the level of intracellular ca(2+) were also investigated. |
2016-02-12 |
2023-08-13 |
rat |
| A A Korotkov, M V Glazova, L S Nikitina, N A Dorofeeva, O D Kirillova, E V Chernigovskay. [MOLECULAR MECHANISMS OF ERK1/2 KINASES REGULATION IN THE GLUTAMATE- AND GABA-ERGIC NEURONS DURING SEIZURE EXPRESSION IN KRUSHINSKY-MOLODKINA RATS]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 101. issue 10. 2016-02-11. PMID:26827493. |
decreased level of vglut2 associated with activation of erk1/2 and exocytosis proteins supposed activation of glutamate release in the hippocampus, while in the temporal cortex diminished activity of erk1/2 and synapsin i associated with vglut2 up-regulation assumed inhibition of glutamatergic transmission. |
2016-02-11 |
2023-08-13 |
rat |
| A A Korotkov, M V Glazova, L S Nikitina, N A Dorofeeva, O D Kirillova, E V Chernigovskay. [MOLECULAR MECHANISMS OF ERK1/2 KINASES REGULATION IN THE GLUTAMATE- AND GABA-ERGIC NEURONS DURING SEIZURE EXPRESSION IN KRUSHINSKY-MOLODKINA RATS]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 101. issue 10. 2016-02-11. PMID:26827493. |
our data let us supposed that decreasing of glutamate release in th& temporal cortex could be a trigger for the inhibition of hippocampal glutamatergic system and the beginning of further ataxia stage. |
2016-02-11 |
2023-08-13 |
rat |
| A A Korotkov, M V Glazova, L S Nikitina, N A Dorofeeva, O D Kirillova, E V Chernigovskay. [MOLECULAR MECHANISMS OF ERK1/2 KINASES REGULATION IN THE GLUTAMATE- AND GABA-ERGIC NEURONS DURING SEIZURE EXPRESSION IN KRUSHINSKY-MOLODKINA RATS]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 101. issue 10. 2016-02-11. PMID:26827493. |
our data demonstrated correlation between expression and activity of exocytosis proteins and erk1/2 mainly in the glutamategic neurons of the hippocampus and the temporal cortex that let us proposed significant role of erk1/2 kinases as a positive regulator of glutamate release and as a result initiation of seizure expression. |
2016-02-11 |
2023-08-13 |
rat |
| Huadong Xu, Panli Zuo, Shirong Wang, Li Zhou, Xiaoxuan Sun, Meiqin Hu, Bin Liu, Qihui Wu, Haiqiang Dou, Bing Liu, Feipeng Zhu, Sasa Teng, Xiaoyu Zhang, Li Wang, Qing Li, Mu Jin, Xinjiang Kang, Wei Xiong, Changhe Wang, Zhuan Zho. Striatal dopamine release in a schizophrenia mouse model measured by electrochemical amperometry in vivo. The Analyst. vol 140. issue 11. 2016-02-10. PMID:25651802. |
our previous results have demonstrated slower kinetics of transmitter release (glutamate release in hippocampus and norepinephrine release in adrenal slice) in a schizophrenia model, dysbindin null-sandy mice. |
2016-02-10 |
2023-08-13 |
mouse |
| C Nasca, B Bigio, D Zelli, F Nicoletti, B S McEwe. Mind the gap: glucocorticoids modulate hippocampal glutamate tone underlying individual differences in stress susceptibility. Molecular psychiatry. vol 20. issue 6. 2016-02-09. PMID:25178162. |
mind the gap: glucocorticoids modulate hippocampal glutamate tone underlying individual differences in stress susceptibility. |
2016-02-09 |
2023-08-13 |
mouse |
| C Nasca, B Bigio, D Zelli, F Nicoletti, B S McEwe. Mind the gap: glucocorticoids modulate hippocampal glutamate tone underlying individual differences in stress susceptibility. Molecular psychiatry. vol 20. issue 6. 2016-02-09. PMID:25178162. |
this approach combined with molecular and behavioral analyses, led us to recognize, in hippocampus, presynaptic mglu2 receptors, which inhibit glutamate release, as a stress-sensitive marker of individual differences to stress-induced mood disorders. |
2016-02-09 |
2023-08-13 |
mouse |