| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A D Stan, S Ghose, C Zhao, K Hulsey, P Mihalakos, M Yanagi, S U Morris, J J Bartko, C Choi, C A Tamming. Magnetic resonance spectroscopy and tissue protein concentrations together suggest lower glutamate signaling in dentate gyrus in schizophrenia. Molecular psychiatry. vol 20. issue 4. 2015-12-09. PMID:24912493. |
in a mouse model with a dg knockout of the grin1 gene, we further confirmed that a selective decrease in dg glun1 is sufficient to decrease the glutamate concentrations in the whole hippocampus. |
2015-12-09 |
2023-08-13 |
mouse |
| X Wang, D Zhang, X-Y L. Dentate gyrus-CA3 glutamate release/NMDA transmission mediates behavioral despair and antidepressant-like responses to leptin. Molecular psychiatry. vol 20. issue 4. 2015-12-09. PMID:25092243. |
the onset of tail suspension stress evoked a rapid increase in glutamate release in hippocampal field ca3, which declined gradually after its offset. |
2015-12-09 |
2023-08-13 |
Not clear |
| Philip V Holmes, Jenny I Reiss, Patrick S Murray, Rod K Dishman, Jessica M Spradle. Chronic exercise dampens hippocampal glutamate overflow induced by kainic acid in rats. Behavioural brain research. vol 284. 2015-12-07. PMID:25668513. |
chronic exercise dampens hippocampal glutamate overflow induced by kainic acid in rats. |
2015-12-07 |
2023-08-13 |
rat |
| Philip V Holmes, Jenny I Reiss, Patrick S Murray, Rod K Dishman, Jessica M Spradle. Chronic exercise dampens hippocampal glutamate overflow induced by kainic acid in rats. Behavioural brain research. vol 284. 2015-12-07. PMID:25668513. |
following three weeks of voluntary wheel running or sedentary conditions, rats were injected with 10 mg/kg of kainic acid, and hippocampal glutamate was measured in real time using a telemetric, in vivo voltammetry system. |
2015-12-07 |
2023-08-13 |
rat |
| Philip V Holmes, Jenny I Reiss, Patrick S Murray, Rod K Dishman, Jessica M Spradle. Chronic exercise dampens hippocampal glutamate overflow induced by kainic acid in rats. Behavioural brain research. vol 284. 2015-12-07. PMID:25668513. |
results of the voltammetry experiment revealed that the rise in hippocampal glutamate induced by kainic acid is attenuated in exercising rats compared to sedentary controls, indicating that the exercise-induced protection against seizures involves regulation of hippocampal glutamate release. |
2015-12-07 |
2023-08-13 |
rat |
| Janet M Finlay, Ginger A Dunham, Analiesse M Isherwood, Chelsea J Newton, Thuyanh V Nguyen, Patricia C Reppar, Ilana Snitkovski, Sarah A Paschall, Robert W Green. Effects of prefrontal cortex and hippocampal NMDA NR1-subunit deletion on complex cognitive and social behaviors. Brain research. vol 1600. 2015-12-04. PMID:25452020. |
glutamate n-methyl-d-aspartate receptors (nmdars) in the medial prefrontal cortex (mpfc) and hippocampus may play an integral role in complex cognitive and social deficits associated with a number of psychiatric illnesses including autism, mood disorders, and schizophrenia. |
2015-12-04 |
2023-08-13 |
mouse |
| Nathan L Hutcheson, Karthik R Sreenivasan, Gopikrishna Deshpande, Meredith A Reid, Jennifer Hadley, David M White, Lawrence Ver Hoef, Adrienne C Laht. Effective connectivity during episodic memory retrieval in schizophrenia participants before and after antipsychotic medication. Human brain mapping. vol 36. issue 4. 2015-12-03. PMID:25504918. |
recent work has identified abnormal hippocampal function in unmedicated patients with schizophrenia (sz), such as increased metabolism and glutamate content that are not always seen in medicated sz. |
2015-12-03 |
2023-08-13 |
human |
| Simone Molz, Gislaine Olescowicz, Jessica Rossana Kraus, Fabiana Kalyne Ludka, Carla I Tasc. Purine receptors are required for DHA-mediated neuroprotection against oxygen and glucose deprivation in hippocampal slices. Purinergic signalling. vol 11. issue 1. 2015-12-01. PMID:25504554. |
we observed that cellular viability reduction induced by experimental ischemia as well as cell damage and thiobarbituric acid reactive substances (tbars) production induced by glutamate (10 mm) were prevented by hippocampal slices pretreated with dha (5 μm). |
2015-12-01 |
2023-08-13 |
Not clear |
| María Guadalupe Valle-Dorado, César Emmanuel Santana-Gómez, Sandra Adela Orozco-Suárez, Luisa Roch. The mast cell stabilizer sodium cromoglycate reduces histamine release and status epilepticus-induced neuronal damage in the rat hippocampus. Neuropharmacology. vol 92. 2015-12-01. PMID:25578265. |
in contrast to ss-se group, rats from the cg-se group showed increased latency to the establishment of the status epilepticus (p = 0.048), absence of wet-dog shakes, reduced histamine (but not gaba and glutamate) release, lower number of mast cells (p = 0.008) and reduced neuronal damage in hippocampus. |
2015-12-01 |
2023-08-13 |
rat |
| M Campolongo, L Benedetti, O L Podhajcer, F Pitossi, A M Depin. Hippocampal SPARC regulates depression-related behavior. Genes, brain, and behavior. vol 11. issue 8. 2015-11-30. PMID:22950524. |
astrocytes control the glutamate receptor levels in the developing hippocampus through sparc secretion. |
2015-11-30 |
2023-08-12 |
mouse |
| Marisa S Ghersi, L A Gabach, F Buteler, A A Vilcaes, H B Schiöth, M F Perez, S R de Bariogli. Ghrelin increases memory consolidation through hippocampal mechanisms dependent on glutamate release and NR2B-subunits of the NMDA receptor. Psychopharmacology. vol 232. issue 10. 2015-11-27. PMID:25466701. |
ghrelin increases memory consolidation through hippocampal mechanisms dependent on glutamate release and nr2b-subunits of the nmda receptor. |
2015-11-27 |
2023-08-13 |
Not clear |
| Xiaomei Jin, Yamin Wang, Xiaojing Li, Xianxing Tan, Zhigang Miao, Yuanyuan Chen, Ronald C Hamdy, Balvin H L Chua, Jiming Kong, Heqing Zhao, Xingshun X. 7,8-Dihydroxy-4-methylcoumarin provides neuroprotection by increasing hippocalcin expression. Neurotoxicity research. vol 27. issue 3. 2015-11-25. PMID:25752619. |
we found that dhmc protected against glutamate toxicity in hippocampal ht-22 cells in a concentration-dependent manner in vitro. |
2015-11-25 |
2023-08-13 |
rat |
| Hyungju Park, Kyung-Seok Han, Jinsoo Seo, Jaekwang Lee, Shashank M Dravid, Junsung Woo, Heejung Chun, Sukhee Cho, Jin Young Bae, Heeyoung An, Woohyun Koh, Bo-Eun Yoon, Rolando Berlinguer-Palmini, Guido Mannaioni, Stephen F Traynelis, Yong Chul Bae, Se-Young Choi, C Justin Le. Channel-mediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic NMDA receptors. Molecular brain. vol 8. 2015-11-23. PMID:25645137. |
channel-mediated astrocytic glutamate modulates hippocampal synaptic plasticity by activating postsynaptic nmda receptors. |
2015-11-23 |
2023-08-13 |
Not clear |
| Yoshihiko Yamazaki, Satoshi Fuji. Extracellular ATP modulates synaptic plasticity induced by activation of metabotropic glutamate receptors in the hippocampus. Biomedical research (Tokyo, Japan). vol 36. issue 1. 2015-11-23. PMID:25749146. |
extracellular atp modulates synaptic plasticity induced by activation of metabotropic glutamate receptors in the hippocampus. |
2015-11-23 |
2023-08-13 |
Not clear |
| Karol Rycerz, Aleksandra Krawczyk, Jadwiga Jaworska-Adamu, Izabela Krawczyk-Mar. Effects of monosodium glutamate treatment on calretinin-immunoreactive neurons in hippocampus of postnatal rats. Folia histochemica et cytobiologica. vol 52. issue 4. 2015-11-17. PMID:25401763. |
effects of monosodium glutamate treatment on calretinin-immunoreactive neurons in hippocampus of postnatal rats. |
2015-11-17 |
2023-08-13 |
rat |
| Samuel Hernández-González, Raúl Ballestín, Rosa López-Hidalgo, Javier Gilabert-Juan, José Miguel Blasco-Ibáñez, Carlos Crespo, Juan Nácher, Emilio Vare. Altered distribution of hippocampal interneurons in the murine Down Syndrome model Ts65Dn. Neurochemical research. vol 40. issue 1. 2015-11-10. PMID:25399236. |
in this report we have analysed, in the hippocampus of ts65dn mice, the expression of synaptic markers: synaptophysin, vesicular glutamate transporter-1 and isoform 67 of the glutamic acid decarboxylase; and of different subtypes of inhibitory neurons (calbindin d-28k, parvalbumin, calretinin, npy, cck, vip and somatostatin). |
2015-11-10 |
2023-08-13 |
mouse |
| M A Saad, R M Abdelsalam, S A Kenawy, A S Atti. Montelukast, a cysteinyl leukotriene receptor-1 antagonist protects against hippocampal injury induced by transient global cerebral ischemia and reperfusion in rats. Neurochemical research. vol 40. issue 1. 2015-11-10. PMID:25403620. |
after reperfusion rats were killed by decapitation, brains were removed and both hippocampi separated and the following biochemical parameters were estimated; lactate dehydrogenase activity, oxidative stress markers (lipid peroxides, nitric oxide and reduced glutathione), inflammatory markers (myeloperoxidase, tumor necrosis factor-alpha, nuclear factor kappa-b, interleukin-6 and interleukin-10), apoptotic biomarkers (caspase 3 and cytochrome c), neurotransmitters (glutamate, gamma aminobutyric acid), cys-lts contents and cyslt1 receptor expression; as well as total brain infarct size and histopathological examination of the hippocampus were assessed. |
2015-11-10 |
2023-08-13 |
human |
| Andrea Mora-Gallegos, Mijail Rojas-Carvajal, Sofía Salas, Adriana Saborío-Arce, Jaime Fornaguera-Trías, Juan C Brene. Age-dependent effects of environmental enrichment on spatial memory and neurochemistry. Neurobiology of learning and memory. vol 118. 2015-11-10. PMID:25434818. |
open-field (oft) and radial-maze (rm) behavior, and ex-vivo contents of gaba and glutamate in hippocampus, and of dopamine and dopac in ventral striatum (vs) were analyzed and compared between the four groups. |
2015-11-10 |
2023-08-13 |
rat |
| Andrea Mora-Gallegos, Mijail Rojas-Carvajal, Sofía Salas, Adriana Saborío-Arce, Jaime Fornaguera-Trías, Juan C Brene. Age-dependent effects of environmental enrichment on spatial memory and neurochemistry. Neurobiology of learning and memory. vol 118. 2015-11-10. PMID:25434818. |
at the neurochemical level, young ee rats showed higher hippocampal glutamate and gaba concentrations, and da turnover in vs, which correlated with rm performance. |
2015-11-10 |
2023-08-13 |
rat |
| Manuella P Kaster, Nuno J Machado, Henrique B Silva, Ana Nunes, Ana Paula Ardais, Magda Santana, Younis Baqi, Christa E Müller, Ana Lúcia S Rodrigues, Lisiane O Porciúncula, Jiang Fan Chen, Ângelo R Tomé, Paula Agostinho, Paula M Canas, Rodrigo A Cunh. Caffeine acts through neuronal adenosine A2A receptors to prevent mood and memory dysfunction triggered by chronic stress. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 25. 2015-11-10. PMID:26056314. |
these behavioral changes were accompanied by synaptic alterations, typified by a decrease in synaptic plasticity and a reduced density of synaptic proteins (synaptosomal-associated protein 25, syntaxin, and vesicular glutamate transporter type 1), together with an increased density of a2ar in glutamatergic terminals in the hippocampus. |
2015-11-10 |
2023-08-13 |
mouse |