| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S B Seredenin, T A Gudashev. [The development of a pharmacologically active low-molecular mimetic of the nerve growth factor]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 115. issue 6. 2015-11-06. PMID:26356399. |
gk-2 showed neuroprotective activity in concentrations up to 10-9М against h(2)o(2) or glutamate or mptp-induced neurotoxicity in РС12, НТ22 cells and primary rat hippocampal neurons. |
2015-11-06 |
2023-08-13 |
mouse |
| Julia Klueva, Eckart D Gundelfinger, R Renato Frischknecht, Martin Hein. Intracellular Ca²⁺ and not the extracellular matrix determines surface dynamics of AMPA-type glutamate receptors on aspiny neurons. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 369. issue 1654. 2015-11-05. PMID:25225098. |
the perisynaptic extracellular matrix (ecm) contributes to the control of the lateral mobility of ampa-type glutamate receptors (ampars) at spine synapses of principal hippocampal neurons. |
2015-11-05 |
2023-08-13 |
Not clear |
| Courtney Sobieski, Xiaoping Jiang, Devon C Crawford, Steven Menneric. Loss of Local Astrocyte Support Disrupts Action Potential Propagation and Glutamate Release Synchrony from Unmyelinated Hippocampal Axon Terminals In Vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 31. 2015-11-05. PMID:26245971. |
loss of local astrocyte support disrupts action potential propagation and glutamate release synchrony from unmyelinated hippocampal axon terminals in vitro. |
2015-11-05 |
2023-08-13 |
rat |
| R Ryley Parrish, A J Albertson, S C Buckingham, J J Hablitz, K L Mascia, W Davis Haselden, F D Lubi. Status epilepticus triggers early and late alterations in brain-derived neurotrophic factor and NMDA glutamate receptor Grin2b DNA methylation levels in the hippocampus. Neuroscience. vol 248. 2015-11-03. PMID:23811393. |
status epilepticus triggers early and late alterations in brain-derived neurotrophic factor and nmda glutamate receptor grin2b dna methylation levels in the hippocampus. |
2015-11-03 |
2023-08-12 |
rat |
| R Ryley Parrish, A J Albertson, S C Buckingham, J J Hablitz, K L Mascia, W Davis Haselden, F D Lubi. Status epilepticus triggers early and late alterations in brain-derived neurotrophic factor and NMDA glutamate receptor Grin2b DNA methylation levels in the hippocampus. Neuroscience. vol 248. 2015-11-03. PMID:23811393. |
status epilepticus (se) triggers abnormal expression of genes in the hippocampus, such as glutamate receptor subunit epsilon-2 (grin2b/nr2b) and brain-derived neurotrophic factor (bdnf), that is thought to occur in temporal lobe epilepsy (tle). |
2015-11-03 |
2023-08-12 |
rat |
| Balwant P Salunke, Sudhir N Umathe, Jagatpalsingh G Chava. Involvement of NMDA receptor in low-frequency magnetic field-induced anxiety in mice. Electromagnetic biology and medicine. vol 33. issue 4. 2015-11-02. PMID:24131395. |
in addition, levels of gaba and glutamate were determined in regions of the brain viz, cortex, striatum, hippocampus and hypothalamus. |
2015-11-02 |
2023-08-12 |
mouse |
| Balwant P Salunke, Sudhir N Umathe, Jagatpalsingh G Chava. Involvement of NMDA receptor in low-frequency magnetic field-induced anxiety in mice. Electromagnetic biology and medicine. vol 33. issue 4. 2015-11-02. PMID:24131395. |
experiments demonstrated significant elevation of gaba and glutamate levels in the hippocampus and hypothalamus. |
2015-11-02 |
2023-08-12 |
mouse |
| Joana Fernandes, Marta Vieira, Laura Carreto, Manuel A S Santos, Carlos B Duarte, Ana Luísa Carvalho, Armanda E Santo. In vitro ischemia triggers a transcriptional response to down-regulate synaptic proteins in hippocampal neurons. PloS one. vol 9. issue 6. 2015-11-02. PMID:24960035. |
additionally, ogd decreased the mrna and protein expression levels of the glua1 ampa receptor subunit as well as the glun2a and glun2b subunits of nmda receptors, but increased the mrna expression of the glun3a subunit, thus altering the composition of ionotropic glutamate receptors in hippocampal neurons. |
2015-11-02 |
2023-08-13 |
Not clear |
| M Pérez-Domínguez, R Hernández-Benítez, C Peña Segura, H Pasantes-Morale. Thrombin-facilitated efflux of D-[3H]-aspartate from cultured astrocytes and neurons under hyponatremia and chemical ischemia. Neurochemical research. vol 39. issue 7. 2015-10-19. PMID:24706094. |
thrombin effect increasing swelling-induced glutamate efflux was examined in cultured cortical astrocytes, cerebellar granule neurons (cgn), hippocampal and cortical neurons. |
2015-10-19 |
2023-08-13 |
Not clear |
| Citlalli Netzahualcoyotzi, Ricardo Tapi. Energy substrates protect hippocampus against endogenous glutamate-mediated neurodegeneration in awake rats. Neurochemical research. vol 39. issue 7. 2015-10-19. PMID:24789366. |
we conclude that ketone bodies possess weak anticonvulsant effects and that energy metabolism impairment plays a more important role than oxidative stress in the delayed hippocampal neurodegeneration resulting from the excitotoxic action of 4-ap mediated by endogenous glutamate. |
2015-10-19 |
2023-08-13 |
rat |
| Shu-Ling Liang, Bradley E Alger, Margaret M McCarth. Developmental increase in hippocampal endocannabinoid mobilization: role of metabotropic glutamate receptor subtype 5 and phospholipase C. Journal of neurophysiology. vol 112. issue 10. 2015-10-19. PMID:25185819. |
developmental increase in hippocampal endocannabinoid mobilization: role of metabotropic glutamate receptor subtype 5 and phospholipase c. endocannabinoids (ecbs) released from postsynaptic neurons mediate retrograde suppression of neurotransmitter release at central synapses. |
2015-10-19 |
2023-08-13 |
rat |
| Mariko Kato Hayashi, Masato Yasu. The transmembrane transporter domain of glutamate transporters is a process tip localizer. Scientific reports. vol 5. 2015-10-16. PMID:25761899. |
the transmembrane transporter domain fragments of glutamate transporters also localized to astrocyte process tips in cultured hippocampal slice. |
2015-10-16 |
2023-08-13 |
Not clear |
| Martha Catalina Rivera-Cervantes, Rolando Castañeda-Arellano, Ruben Darío Castro-Torres, Graciela Gudiño-Cabrera, Alfredo I Feria y Velasco, Antoni Camins, Carlos Beas-Zárat. P38 MAPK inhibition protects against glutamate neurotoxicity and modifies NMDA and AMPA receptor subunit expression. Journal of molecular neuroscience : MN. vol 55. issue 3. 2015-10-15. PMID:25172309. |
we assessed whether excitotoxicity induced by neonatal treatment with monosodium glutamate in rats at postnatal age of 1, 3, 5, and 7 modifies the hippocampal expression of the nmdar subunit nr1 and the ampar subunits glur1/glur2 at postnatal days 8, 10, 12, and 14. |
2015-10-15 |
2023-08-13 |
rat |
| Martha Catalina Rivera-Cervantes, Rolando Castañeda-Arellano, Ruben Darío Castro-Torres, Graciela Gudiño-Cabrera, Alfredo I Feria y Velasco, Antoni Camins, Carlos Beas-Zárat. P38 MAPK inhibition protects against glutamate neurotoxicity and modifies NMDA and AMPA receptor subunit expression. Journal of molecular neuroscience : MN. vol 55. issue 3. 2015-10-15. PMID:25172309. |
our results showed that monosodium glutamate induces neuronal death and alters the expression of the subunits evaluated in the hippocampus at all ages studied, which could be prevented by sb203580 treatment.furthermore, expression of the nrsf gene silencing factor also increased in response to excitotoxicity, suggesting a relationship in suppressing glur2-expression, which was regulated by the p38-mapk pathway inhibitor sb203580. |
2015-10-15 |
2023-08-13 |
rat |
| Pietro Baldelli, Jacopo Meldoles. The Transcription Repressor REST in Adult Neurons: Physiology, Pathology, and Diseases eNeuro. vol 2. issue 4. 2015-10-14. PMID:26465007. |
examples of ca1 hippocampal neuron protection upon depolarization, and of neurodegeneration upon glutamate treatment and hypoxia have been reported. |
2015-10-14 |
2023-08-13 |
human |
| Yue-Hong Li, Chun-Lai Zhang, Xiao-Yan Zhang, Hong-Xia Zhou, Ling-Li Men. Effects of mild induced hypothermia on hippocampal connexin 43 and glutamate transporter 1 expression following traumatic brain injury in rats. Molecular medicine reports. vol 11. issue 3. 2015-10-12. PMID:25394735. |
effects of mild induced hypothermia on hippocampal connexin 43 and glutamate transporter 1 expression following traumatic brain injury in rats. |
2015-10-12 |
2023-08-13 |
rat |
| Yue-Hong Li, Chun-Lai Zhang, Xiao-Yan Zhang, Hong-Xia Zhou, Ling-Li Men. Effects of mild induced hypothermia on hippocampal connexin 43 and glutamate transporter 1 expression following traumatic brain injury in rats. Molecular medicine reports. vol 11. issue 3. 2015-10-12. PMID:25394735. |
the aim of the present study was to investigate the effects of mild induced hypothermia (mih) on the expression of connexin 43 (cx43) and glutamate transporter 1 (glt‑1) in the hippocampus following tbi in rats. |
2015-10-12 |
2023-08-13 |
rat |
| Liran Hazan, Inna Gaisler-Salomo. Glutaminase1 heterozygous mice show enhanced trace fear conditioning and Arc/Arg3.1 expression in hippocampus and cingulate cortex. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 24. issue 12. 2015-10-09. PMID:25453483. |
mice heterozygous for a mutation in the glutaminase (gls1) gene (gls1 hz mice), with reduced glutamate recycling and release, display reduced hippocampal function as well as memory of contextual cues in a delay fear conditioning (fc) paradigm. |
2015-10-09 |
2023-08-13 |
mouse |
| Mei Huang, Anna R Felix, Dorothy G Flood, Chaya Bhuvaneswaran, Dana Hilt, Gerhard Koenig, Herbert Y Meltze. The novel α7 nicotinic acetylcholine receptor agonist EVP-6124 enhances dopamine, acetylcholine, and glutamate efflux in rat cortex and nucleus accumbens. Psychopharmacology. vol 231. issue 23. 2015-10-07. PMID:24810107. |
increased release of dopamine (da), acetylcholine (ach), glutamate (glu), and γ-aminobutyric acid (gaba) in cerebral cortex, hippocampus, and nucleus accumbens (nac) has been suggested to contribute to their beneficial effects on cognition. |
2015-10-07 |
2023-08-13 |
rat |
| Y-Z Pan, P A Ruteck. Enhanced excitatory synaptic network activity following transient group I metabotropic glutamate activation. Neuroscience. vol 275. 2015-10-07. PMID:24928353. |
prolonged activation of group i metabotropic glutamate receptors (mglurs) using the agonist (s)-3,5-dihydroxyphenylglycine (dhpg) produces long-lasting changes in the ca3 region of the hippocampal slice. |
2015-10-07 |
2023-08-13 |
rat |