| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Glavan, R Zorec, K Babic, D Sket, M Zivi. Dopaminergic regulation of synaptotagmin I and IV mRNAs in hemiparkinsonian rats. Neuroreport. vol 11. issue 18. 2001-03-29. PMID:11192626. |
we conclude that chronic lack of dopamine and treatment with dopamine d1 receptor agonists alter the synaptic plasticity in dopamine depleted basal ganglia. |
2001-03-29 |
2023-08-12 |
rat |
| M Yamaya, M Yanai, T Ohrui, H Arai, H Sasak. Interventions to prevent pneumonia among older adults. Journal of the American Geriatrics Society. vol 49. issue 1. 2001-03-22. PMID:11207848. |
similarly, since the production of substance p is regulated by dopaminergic neurons in the cerebral basal ganglia, treatment with dopamine analogs or potentiating drugs such as amantadine (and, of course, prevention of cerebral vascular disease, which can result in basal ganglia strokes) should affect the incidence of pneumonia. |
2001-03-22 |
2023-08-12 |
Not clear |
| T Hayakawa, M C Chang, S I Rapoport, N M Appe. Selective dopamine receptor stimulation differentially affects [3H]arachidonic acid incorporation, a surrogate marker for phospholipase A2-mediated neurotransmitter signal transduction, in a rodent model of Parkinson's disease. The Journal of pharmacology and experimental therapeutics. vol 296. issue 3. 2001-03-15. PMID:11181943. |
the data suggest up-regulation in basal ganglia and cortical dopamine circuits mediated by phospholipase a(2) ipsilateral to the substantia nigra lesion. |
2001-03-15 |
2023-08-12 |
rat |
| T González-Hernández, P Barroso-Chinea, A Acevedo, E Salido, M Rodrígue. Colocalization of tyrosine hydroxylase and GAD65 mRNA in mesostriatal neurons. The European journal of neuroscience. vol 13. issue 1. 2001-03-01. PMID:11135004. |
contrasting with the idea that in the basal ganglia, dopamine and gaba are released from different cell populations, the results suggest a more complex dopamine/gaba interaction than previously assumed, probably including cotransmission. |
2001-03-01 |
2023-08-12 |
rat |
| R Zanardi, F Artigas, R Moresco, C Colombo, C Messa, C Gobbo, E Smeraldi, F Fazi. Increased 5-hydroxytryptamine-2 receptor binding in the frontal cortex of depressed patients responding to paroxetine treatment: a positron emission tomography scan study. Journal of clinical psychopharmacology. vol 21. issue 1. 2001-03-01. PMID:11199948. |
[18f]fluoro-ethyl-spiperone labels 5-ht2a receptors in the cortex and dopamine d2 receptors in the basal ganglia. |
2001-03-01 |
2023-08-12 |
human |
| A Kaelin-Lang, P Liniger, A Probst, T Lauterburg, J M Burgunde. Adenosine A2A receptor gene expression in the normal striatum and after 6-OH-dopamine lesion. Journal of neural transmission (Vienna, Austria : 1996). vol 107. issue 8-9. 2001-02-15. PMID:11041267. |
the maintained inhibitory function of a2a r on motor activity in spite of dopamine depletion could be partly responsible for the depression of locomotor activity observed in basal ganglia disorders such as parkinson's disease. |
2001-02-15 |
2023-08-12 |
mouse |
| Y Smith, J Z Kieva. Anatomy of the dopamine system in the basal ganglia. Trends in neurosciences. vol 23. issue 10 Suppl. 2001-02-08. PMID:11052217. |
the local dendritic release of dopamine by neurons in the substantia nigra pars compacta and ventral tegmental also influences basal ganglia functions. |
2001-02-08 |
2023-08-12 |
Not clear |
| Y Smith, J Z Kieva. Anatomy of the dopamine system in the basal ganglia. Trends in neurosciences. vol 23. issue 10 Suppl. 2001-02-08. PMID:11052217. |
thus, the long-term belief that the effects of dopamine in the basal ganglia were solely mediated through the nigrostriatal system must be changed to take into account extrastriatal dopaminergic projections and intrastriatal dopaminergic neurons. |
2001-02-08 |
2023-08-12 |
Not clear |
| J R Walters, D N Ruskin, K A Allers, D A Bergstro. Pre- and postsynaptic aspects of dopamine-mediated transmission. Trends in neurosciences. vol 23. issue 10 Suppl. 2001-02-08. PMID:11052219. |
dopamine agonist administration induces changes in firing rate and pattern in basal ganglia nuclei that provide an insight into the role of dopamine in basal ganglia function. |
2001-02-08 |
2023-08-12 |
Not clear |
| D J Brook. PET studies and motor complications in Parkinson's disease. Trends in neurosciences. vol 23. issue 10 Suppl. 2001-02-08. PMID:11052227. |
additional pet studies suggest that loss of striatal dopamine storage capacity along with pulsatile exposure to exogenous l-dopa results in pathologically raised synaptic dopamine levels and deranged basal ganglia opioid transmission.this, rather than altered dopamine receptor binding, then causes inappropriate overactivity of basal ganglia-frontal projections, resulting in breakthrough involuntary movements. |
2001-02-08 |
2023-08-12 |
Not clear |
| T Hashimot. [Pathophysiology of abnormal movements in Parkinson's disease]. Nihon rinsho. Japanese journal of clinical medicine. vol 58. issue 10. 2001-02-01. PMID:11068437. |
major parkinsonian motor symptoms, i.e., bradykinesia, muscular rigidity, and resting tremor, are due to abnormalities in the motor circuit of the basal ganglia caused by loss of nigrostriatal dopamine neurons. |
2001-02-01 |
2023-08-12 |
Not clear |
| J A Obeso, M C Rodriguez-Oroz, M Rodriguez, R Macias, L Alvarez, J Guridi, J Vitek, M R DeLon. Pathophysiologic basis of surgery for Parkinson's disease. Neurology. vol 55. issue 12 Suppl 6. 2001-02-01. PMID:11188978. |
dopamine depletion induces a series of changes in the basal ganglia motor circuit that underlie the origin of the cardinal features of parkinson's disease. |
2001-02-01 |
2023-08-12 |
Not clear |
| F I Tarazi, K Zhang, R J Baldessarin. Effects of nigrostriatal dopamine denervation on ionotropic glutamate receptors in rat caudate-putamen. Brain research. vol 881. issue 1. 2000-12-12. PMID:11033095. |
the findings indicate that nigrostriatal dopamine denervation can selectively enhance ka receptor levels in rat basal ganglia, suggest that ka receptors contribute to the pathophysiology of parkinson's disease, and may suggest innovative treatments. |
2000-12-12 |
2023-08-12 |
rat |
| J Kulisevsk. Role of dopamine in learning and memory: implications for the treatment of cognitive dysfunction in patients with Parkinson's disease. Drugs & aging. vol 16. issue 5. 2000-11-13. PMID:10917074. |
instead, it may be a function of the level of dopamine depletion in different parts of the basal ganglia and prefrontal cortex. |
2000-11-13 |
2023-08-12 |
human |
| M G Murer, G Dziewczapolski, P Salin, M Vila, K Y Tseng, M Ruberg, M Rubinstein, M A Kelly, D K Grandy, M J Low, E Hirsch, R Raisman-Vozari, O Gershani. The indirect basal ganglia pathway in dopamine D(2) receptor-deficient mice. Neuroscience. vol 99. issue 4. 2000-11-07. PMID:10974427. |
the indirect basal ganglia pathway in dopamine d(2) receptor-deficient mice. |
2000-11-07 |
2023-08-12 |
mouse |
| M G Murer, G Dziewczapolski, P Salin, M Vila, K Y Tseng, M Ruberg, M Rubinstein, M A Kelly, D K Grandy, M J Low, E Hirsch, R Raisman-Vozari, O Gershani. The indirect basal ganglia pathway in dopamine D(2) receptor-deficient mice. Neuroscience. vol 99. issue 4. 2000-11-07. PMID:10974427. |
recent pathophysiological models of basal ganglia function in parkinson's disease predict that specific neurochemical changes in the indirect pathway would follow the lack of stimulation of d(2) dopamine receptors. |
2000-11-07 |
2023-08-12 |
mouse |
| M Segaw. Development of the nigrostriatal dopamine neuron and the pathways in the basal ganglia. Brain & development. vol 22 Suppl 1. 2000-11-07. PMID:10984655. |
development of the nigrostriatal dopamine neuron and the pathways in the basal ganglia. |
2000-11-07 |
2023-08-12 |
Not clear |
| M Segaw. Development of the nigrostriatal dopamine neuron and the pathways in the basal ganglia. Brain & development. vol 22 Suppl 1. 2000-11-07. PMID:10984655. |
the nigrostriatal (ns) dopamine (da) neuron and the basal ganglia show marked functional age variation in the first three decades. |
2000-11-07 |
2023-08-12 |
Not clear |
| P Svenningsson, L Gunne, P E Andre. L-DOPA produces strong induction of c-fos messenger RNA in dopamine-denervated cortical and striatal areas of the common marmoset. Neuroscience. vol 99. issue 3. 2000-11-07. PMID:11029538. |
the effects of l-dopa probably depend both on a direct activation of supersensitized dopamine receptors by dopamine produced in the few remaining, but hyperactive, dopaminergic nerve terminals and in serotonergic nerve terminals, as well as on indirect actions of l-dopa related to activation of circuitries connecting cerebral cortex and basal ganglia structures. |
2000-11-07 |
2023-08-12 |
marmoset |
| R M Moresco, C Colombo, F Fazio, A Bonfanti, G Lucignani, C Messa, C Gobbo, L Galli, A Del Sole, A Lucca, E Smerald. Effects of fluvoxamine treatment on the in vivo binding of [F-18]FESP in drug naive depressed patients: a PET study. NeuroImage. vol 12. issue 4. 2000-11-01. PMID:10988039. |
drug effect was evaluated in different cortical areas and in the basal ganglia by positron emission tomography (pet) and fluoro-ethyl-spiperone ([(18)f]fesp), an high affinity 5ht(2) serotonin and d(2) dopamine receptors antagonist. |
2000-11-01 |
2023-08-12 |
Not clear |