| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D N Ruskin, D A Bergstrom, C W Mastropietro, M J Twery, J R Walter. Dopamine agonist-mediated rotation in rats with unilateral nigrostriatal lesions is not dependent on net inhibitions of rate in basal ganglia output nuclei. Neuroscience. vol 91. issue 3. 1999-10-08. PMID:10391472. |
current models of basal ganglia function predict that dopamine agonist-induced motor activation is mediated by decreases in basal ganglia output. |
1999-10-08 |
2023-08-12 |
rat |
| D N Ruskin, D A Bergstrom, C W Mastropietro, M J Twery, J R Walter. Dopamine agonist-mediated rotation in rats with unilateral nigrostriatal lesions is not dependent on net inhibitions of rate in basal ganglia output nuclei. Neuroscience. vol 91. issue 3. 1999-10-08. PMID:10391472. |
this study examines the relationship between dopamine agonist effects on firing rate in basal ganglia output nuclei and rotational behavior in rats with nigrostriatal lesions. |
1999-10-08 |
2023-08-12 |
rat |
| D N Ruskin, D A Bergstrom, C W Mastropietro, M J Twery, J R Walter. Dopamine agonist-mediated rotation in rats with unilateral nigrostriatal lesions is not dependent on net inhibitions of rate in basal ganglia output nuclei. Neuroscience. vol 91. issue 3. 1999-10-08. PMID:10391472. |
the results show that decreases in firing rate in basal ganglia output nuclei are not necessary for dopamine agonist-induced motor activation. |
1999-10-08 |
2023-08-12 |
rat |
| D Wirtshafter, K E Asi. Haloperidol induces Fos expression in the globus pallidus and substantia nigra of cynomolgus monkeys. Brain research. vol 835. issue 2. 1999-09-28. PMID:10415370. |
these findings are consistent with models of basal ganglia organization which predict that blockade of dopamine receptors should result in a disinhibition of cells in these structures. |
1999-09-28 |
2023-08-12 |
monkey |
| Z B You, M Herrera-Marschitz, L Tereniu. Modulation of neurotransmitter release in the basal ganglia of the rat brain by dynorphin peptides. The Journal of pharmacology and experimental therapeutics. vol 290. issue 3. 1999-09-21. PMID:10454508. |
microinjection studies have found that although dynorphin peptides decrease dopamine release in the rat basal ganglia, the nonselective opiate antagonist naloxone produces the opposite effect. |
1999-09-21 |
2023-08-12 |
rat |
| J M Henderson, L E Annett, L J Ryan, W Chiang, S Hidaka, E M Torres, S B Dunnet. Subthalamic nucleus lesions induce deficits as well as benefits in the hemiparkinsonian rat. The European journal of neuroscience. vol 11. issue 8. 1999-09-10. PMID:10457171. |
lesions of the subthalamic nucleus can restore some imbalances in motor output of the basal ganglia induced by nigrostriatal dopamine depletion, and have been proposed as a potential therapy for parkinson's disease. |
1999-09-10 |
2023-08-12 |
rat |
| M C Sañudo-Peña, K Tsou, J M Walke. Motor actions of cannabinoids in the basal ganglia output nuclei. Life sciences. vol 65. issue 6-7. 1999-09-08. PMID:10462071. |
the levels of cb1 cannabinoid receptors in the basal ganglia are the highest in the brain, comparable to the levels of dopamine receptors, a major transmitter in the basal ganglia. |
1999-09-08 |
2023-08-12 |
Not clear |
| T Laasonen-Balk, J Kuikka, H Viinamäki, M Husso-Saastamoinen, J Lehtonen, J Tiihone. Striatal dopamine transporter density in major depression. Psychopharmacology. vol 144. issue 3. 1999-09-02. PMID:10435396. |
there are no previous data available regarding [123i]beta-cit binding to the dopamine transporter sites in the basal ganglia in depressed patients. |
1999-09-02 |
2023-08-12 |
Not clear |
| R D Mayfield, B A Jones, H A Miller, J K Simosky, G A Larson, N R Zahnise. Modulation of endogenous GABA release by an antagonistic adenosine A1/dopamineD1 receptor interaction in rat brain limbic regions but not basal ganglia. Synapse (New York, N.Y.). vol 33. issue 4. 1999-08-30. PMID:10421708. |
however, in basal ganglia, consistent dopamine d(1) receptor modulation of gaba, release was not observed in response to either d(1) agonists or antagonists. |
1999-08-30 |
2023-08-12 |
rat |
| R M Cohen, R E Carson, R J Wyatt, D J Doude. Opiate receptor avidity is reduced bilaterally in rhesus monkeys unilaterally lesioned with MPTP. Synapse (New York, N.Y.). vol 33. issue 4. 1999-08-30. PMID:10421709. |
these findings confirm that the opiate pathway can change in response to modest decreases in basal ganglia dopamine innervation. |
1999-08-30 |
2023-08-12 |
monkey |
| S R Choi, M P Kung, K Plössl, S Meegalla, H F Kun. An improved kit formulation of a dopamine transporter imaging agent: [Tc-99m]TRODAT-1. Nuclear medicine and biology. vol 26. issue 4. 1999-08-05. PMID:10382851. |
this tracer displayed excellent specific binding to dopamine transporters in the basal ganglia region of the brain, thus it is potentially useful for the diagnosis of deficit of dopamine transporters in neurodegenerative diseases, such as parkinson's disease. |
1999-08-05 |
2023-08-12 |
rat |
| G Flores, J J Liang, A Sierra, D Martínez-Fong, R Quirion, J Aceves, L K Srivastav. Expression of dopamine receptors in the subthalamic nucleus of the rat: characterization using reverse transcriptase-polymerase chain reaction and autoradiography. Neuroscience. vol 91. issue 2. 1999-08-02. PMID:10366012. |
these results reinforce the idea that dopamine receptors in the subthalamic nucleus may play an important role in the physiology of the basal ganglia and in the pathophysiology of parkinson's disease. |
1999-08-02 |
2023-08-12 |
rat |
| D N Ruskin, D A Bergstrom, Y Kaneoke, B N Patel, M J Twery, J R Walter. Multisecond oscillations in firing rate in the basal ganglia: robust modulation by dopamine receptor activation and anesthesia. Journal of neurophysiology. vol 81. issue 5. 1999-06-14. PMID:10322046. |
the data demonstrate significant structure in basal ganglia neuron spiking activity at unexpectedly long time scales, as well as a novel effect of dopamine on firing pattern in this slow temporal domain. |
1999-06-14 |
2023-08-12 |
rat |
| F X Vollenweider, P Vontobel, D Hell, K L Leender. 5-HT modulation of dopamine release in basal ganglia in psilocybin-induced psychosis in man--a PET study with [11C]raclopride. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 20. issue 5. 1999-06-09. PMID:10192823. |
5-ht modulation of dopamine release in basal ganglia in psilocybin-induced psychosis in man--a pet study with [11c]raclopride. |
1999-06-09 |
2023-08-12 |
human |
| F S Pidcock, A H Hoon, M V Johnsto. Trihexyphenidyl in posthemorrhagic dystonia: motor and language effects. Pediatric neurology. vol 20. issue 3. 1999-06-07. PMID:10207932. |
the mechanism of action of trihexyphenidyl is believed to be in the basal ganglia where it inhibits muscarinic cholinergic receptors and increases the turnover of dopamine. |
1999-06-07 |
2023-08-12 |
Not clear |
| T Nagatsu, H Ichinos. Molecular biology of catecholamine-related enzymes in relation to Parkinson's disease. Cellular and molecular neurobiology. vol 19. issue 1. 1999-06-04. PMID:10079965. |
in juvenile parkinsonism and parkinson's disease, which have dopamine deficiency in the basal ganglia as hpd/drd, the gch gene may be normal, and the molecular mechanism of the dopamine deficiency in the basal ganglia is different from that in hpd/drd. |
1999-06-04 |
2023-08-12 |
Not clear |
| L Matuszewich, B K Yamamot. Modulation of GABA release by dopamine in the substantia nigra. Synapse (New York, N.Y.). vol 32. issue 1. 1999-06-01. PMID:10188635. |
local interactions between dopamine and gaba in the substantia nigra may have important implications for the direct regulation of basal ganglia efferent activity and motor behavior. |
1999-06-01 |
2023-08-12 |
rat |
| M Morissette, M Goulet, R Grondin, P Blanchet, P J Bédard, T Di Paolo, D Lévesqu. Associative and limbic regions of monkey striatum express high levels of dopamine D3 receptors: effects of MPTP and dopamine agonist replacement therapies. The European journal of neuroscience. vol 10. issue 8. 1999-05-26. PMID:9767387. |
in the present study, we investigated the functional neuroanatomy of the dopamine d3 receptor subtype in the monkey (macaca fascicularis) basal ganglia. |
1999-05-26 |
2023-08-12 |
rat |
| R D Todd, J S Perlmutte. Mutational and biochemical analysis of dopamine in dystonia: evidence for decreased dopamine D2 receptor inhibition. Molecular neurobiology. vol 16. issue 2. 1999-05-21. PMID:9588625. |
we recently proposed that hypofunction of dopamine d2 receptor-mediated inhibition of the indirect output pathway of the basal ganglia can result in dystonia. |
1999-05-21 |
2023-08-12 |
mouse |
| H Miwa, K Nishi, T Fuwa, Y Mizun. Globus pallidus lesions inhibit the induction of c-Fos by haloperidol in the basal ganglia output nuclei in rats. Neuroscience letters. vol 250. issue 1. 1999-05-19. PMID:9696058. |
since it has been suggested that c-fos expression in the snr/ep is caused by increased excitatory inputs from the subthalamic nucleus (stn), the present results provide functional evidence indicating that neuronal activities of the basal ganglia output nuclei are not increased by gp ablation, unlike d2 receptor blockade, supporting the recently proposed hypothesis that overactivity of the stn resulting from dopamine depletion is not solely a result of disinhibition from inhibitory gp efferents. |
1999-05-19 |
2023-08-12 |
rat |