Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
B Spil. [Present views on pathogenesis of schizophrenia]. Psychiatria polska. vol 33. issue 3. 2000-06-14. PMID:10786237. |
particularly, the author suggests that diathesis for schizophrenia involves functional excess of dopamine activity in the basal ganglia. |
2000-06-14 |
2023-08-12 |
Not clear |
K Steece-Collier, L K Chambers, S S Jaw-Tsai, F S Menniti, J T Greenamyr. Antiparkinsonian actions of CP-101,606, an antagonist of NR2B subunit-containing N-methyl-d-aspartate receptors. Experimental neurology. vol 163. issue 1. 2000-06-13. PMID:10785463. |
in the setting of nigrostriatal dopamine depletion, glutamatergic pathways to the striatum and basal ganglia output nuclei become overactive. |
2000-06-13 |
2023-08-12 |
rat |
R Bauer, P Brust, B Walter, G Vorwieger, R Bergmann, F Füchtner, J Steinbach, E el-Hallag, A Fritz, B Johannsen, U Zwiene. Relation between brain tissue pO2 and dopamine synthesis of basal ganglia--a 18FDOPA-PET study in newborn piglets. Journal of perinatal medicine. vol 28. issue 1. 2000-06-08. PMID:10765515. |
relation between brain tissue po2 and dopamine synthesis of basal ganglia--a 18fdopa-pet study in newborn piglets. |
2000-06-08 |
2023-08-12 |
Not clear |
R J McPherson, J F Marshal. Substantia nigra glutamate antagonists produce contralateral turning and basal ganglia Fos expression: interactions with D1 and D2 dopamine receptor agonists. Synapse (New York, N.Y.). vol 36. issue 3. 2000-06-06. PMID:10819899. |
experiments measuring behavior and immediate-early gene expression in the basal ganglia can reveal interactions between dopamine (da) and glutamate neurotransmission. |
2000-06-06 |
2023-08-12 |
rat |
S Z Meng, J Ohyu, M Itoh, S Takashim. Dopamine transporter and nitric oxide synthase in hypoxic-ischemic brain. Pediatric neurology. vol 22. issue 2. 2000-05-11. PMID:10738916. |
changes in dopamine transporter and neuronal nitric oxide synthase (nnos) were investigated by immunohistochemistry in 18 cases of hypoxic-ischemic basal ganglia necrosis. |
2000-05-11 |
2023-08-12 |
human |
S Z Meng, J Ohyu, M Itoh, S Takashim. Dopamine transporter and nitric oxide synthase in hypoxic-ischemic brain. Pediatric neurology. vol 22. issue 2. 2000-05-11. PMID:10738916. |
neuropil dopamine transporter immunostaining in the striatum was increased in seven cases, with relatively mild basal ganglia necrosis, and decreased in four cases, with marked basal ganglia necrosis, compared with age-matched control subjects. |
2000-05-11 |
2023-08-12 |
human |
S Z Meng, J Ohyu, M Itoh, S Takashim. Dopamine transporter and nitric oxide synthase in hypoxic-ischemic brain. Pediatric neurology. vol 22. issue 2. 2000-05-11. PMID:10738916. |
the results suggest that the synthesis of dopamine transporter is up-regulated in relatively mild basal ganglia necrosis to compensate for the uptake of increased dopamine, that this compensative ability is lost in marked basal ganglia necrosis, and that nnos-containing neurons in the striatum are relatively resistant to hypoxic ischemia. |
2000-05-11 |
2023-08-12 |
human |
D Joel, I Weine. The connections of the dopaminergic system with the striatum in rats and primates: an analysis with respect to the functional and compartmental organization of the striatum. Neuroscience. vol 96. issue 3. 2000-04-27. PMID:10717427. |
based on the anatomical data and known dopamine cell physiology, we forward an hypothesis regarding the influence of the basal ganglia on dopamine cell activity which captures at least part of the complex interplay taking place within the substantia nigra between projections arising from the different basal ganglia nuclei. |
2000-04-27 |
2023-08-12 |
rat |
J Radulovic, T Blank, I Nijholt, J Kammermeier, J Spies. In vivo NMDA/dopamine interaction resulting in Fos production in the limbic system and basal ganglia of the mouse brain. Brain research. Molecular brain research. vol 75. issue 2. 2000-04-21. PMID:10686348. |
these data suggest that nmda and dopamine receptors regulate fos production within the limbic system and basal ganglia through regionally differentiated but interdependent actions. |
2000-04-21 |
2023-08-12 |
mouse |
M Filio. Physiologic basis of dyskinesia. Annals of neurology. vol 47. issue 4 Suppl 1. 2000-04-21. PMID:10762130. |
a major criterion for selection in the basal ganglia is prediction of reward, materialized by release of dopamine. |
2000-04-21 |
2023-08-12 |
Not clear |
C R Gerfe. Dopamine-mediated gene regulation in models of Parkinson's disease. Annals of neurology. vol 47. issue 4 Suppl 1. 2000-04-21. PMID:10762131. |
the normal functioning of the basal ganglia is dependent on dopamine maintaining a balance between the two major output pathways of the striatum, through the d1 and d2 dopamine receptors, which have opposing effects on these pathways. |
2000-04-21 |
2023-08-12 |
Not clear |
L Y Moy, G D Zeevalk, P K Sonsall. Role for dopamine in malonate-induced damage in vivo in striatum and in vitro in mesencephalic cultures. Journal of neurochemistry. vol 74. issue 4. 2000-04-11. PMID:10737624. |
in addition, the reactive metabolites generated from the metabolism and oxidation of the neurotransmitter dopamine (da) are thought to contribute to the damage to neurons of the basal ganglia. |
2000-04-11 |
2023-08-12 |
mouse |
R Betarbet, R H Porter, J T Greenamyr. GluR1 glutamate receptor subunit is regulated differentially in the primate basal ganglia following nigrostriatal dopamine denervation. Journal of neurochemistry. vol 74. issue 3. 2000-03-09. PMID:10693949. |
glur1 glutamate receptor subunit is regulated differentially in the primate basal ganglia following nigrostriatal dopamine denervation. |
2000-03-09 |
2023-08-12 |
Not clear |
R Betarbet, R H Porter, J T Greenamyr. GluR1 glutamate receptor subunit is regulated differentially in the primate basal ganglia following nigrostriatal dopamine denervation. Journal of neurochemistry. vol 74. issue 3. 2000-03-09. PMID:10693949. |
the down-regulation of glur1 expression in the output nuclei of the basal ganglia, the internal segment of the globus pallidus and the substantia nigra pars reticulata, may be a compensation for the overactive glutamatergic input from subthalamic nucleus, which arises after striatal dopamine denervation. |
2000-03-09 |
2023-08-12 |
Not clear |
O L Eradiri, M S Star. Striatal dopamine depletion and behavioural sensitization induced by methamphetamine and 3-nitropropionic acid. European journal of pharmacology. vol 386. issue 2-3. 2000-02-29. PMID:10618473. |
these results show that combined systemic treatment with methamphetamine and 3-nitropropionic acid partially depletes dopamine in the basal ganglia, rendering the animals supersensitive to dopamine d(2) receptor activation without altering their spontaneous locomotion. |
2000-02-29 |
2023-08-12 |
rat |
V S Barwick, D H Jones, J T Richter, P B Hicks, K A Youn. Subthalamic nucleus microinjections of 5-HT2 receptor antagonists suppress stereotypy in rats. Neuroreport. vol 11. issue 2. 2000-02-29. PMID:10674468. |
because m100,907 does not have appreciable affinity for dopamine d1 and d2 receptors, and since all three agents are 5-ht2 antagonists, the current data suggest that basal ganglia output related to orofacial movements can be significantly modified by 5-ht2 receptors. |
2000-02-29 |
2023-08-12 |
rat |
S Z Meng, Y Ozawa, M Itoh, S Takashim. Developmental and age-related changes of dopamine transporter, and dopamine D1 and D2 receptors in human basal ganglia. Brain research. vol 843. issue 1-2. 2000-01-24. PMID:10528120. |
developmental and age-related changes of dopamine transporter, and dopamine d1 and d2 receptors in human basal ganglia. |
2000-01-24 |
2023-08-12 |
human |
S Z Meng, Y Ozawa, M Itoh, S Takashim. Developmental and age-related changes of dopamine transporter, and dopamine D1 and D2 receptors in human basal ganglia. Brain research. vol 843. issue 1-2. 2000-01-24. PMID:10528120. |
the developmental and age-related changes of the dopamine transporter (dat), and the dopamine d1 and d2 receptor (d1r and d2r) subtypes were investigated in basal ganglia (bg) of human brain. |
2000-01-24 |
2023-08-12 |
human |
H Salim, S Ferré, A Dalal, R A Peterfreund, K Fuxe, J D Vincent, P M Lled. Activation of adenosine A1 and A2A receptors modulates dopamine D2 receptor-induced responses in stably transfected human neuroblastoma cells. Journal of neurochemistry. vol 74. issue 1. 2000-01-18. PMID:10617149. |
adenosine can influence dopaminergic neurotransmission in the basal ganglia via postsynaptic interaction between adenosine a2a and dopamine d2 receptors. |
2000-01-18 |
2023-08-12 |
human |
F Musshoff, P Schmidt, R Dettmeyer, F Priemer, H Wittig, B Made. A systematic regional study of dopamine and dopamine-derived salsolinol and norsalsolinol levels in human brain areas. Forensic science international. vol 105. issue 1. 2000-01-11. PMID:10605071. |
the regional distribution of dopamine in 32 brains was similar to previous reports with highest concentrations in the basal ganglia, especially in the striatum, followed by the substantia nigra and the hypothalamus. |
2000-01-11 |
2023-08-12 |
human |