| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna Sara Liberati, Giulio Perrott. Neuroanatomical and functional correlates in tic disorders and Tourette's syndrome: A narrative review. Ibrain. vol 10. issue 4. 2024-12-18. PMID:39691418. |
from a neurophysiological perspective, the disorder has classically been associated with neurochemical imbalances (particularly dopamine and serotonin) and structural and functional alterations affecting, in particular, brain areas and circuits involved in the processing and coordination of movements: the basal ganglia, thalamus, motor cortical area, and cingulate cortex; however, more recent research is demonstrating the involvement of many more brain regions and neurotransmission systems than previously observed, such as the prefrontal cortex and cerebellum. |
2024-12-18 |
2024-12-21 |
Not clear |
| José L Lanciego, José A Obes. Functional Neuroanatomy of the Normal and Pathological Basal Ganglia. Cold Spring Harbor perspectives in medicine. 2024-12-18. PMID:39694693. |
dopamine released from the substantia nigra is the underlying driving force keeping the basal ganglia network under proper equilibrium and, indeed, reduction of dopamine levels triggers basal ganglia dysfunction, setting the groundwork for several movement disorders. |
2024-12-18 |
2024-12-21 |
Not clear |
| Correction for Wärnberg and Kumar, Feasibility of dopamine as a vector-valued feedback signal in the basal ganglia. Proceedings of the National Academy of Sciences of the United States of America. vol 121. issue 52. 2024-12-16. PMID:39680785. |
correction for wärnberg and kumar, feasibility of dopamine as a vector-valued feedback signal in the basal ganglia. |
2024-12-16 |
2024-12-21 |
Not clear |
| Desirée Conti, Giulia Bechi Gabrielli, Massimiliano Panigutti, Giulia Zazzaro, Giuseppe Bruno, Gaspare Galati, Fabrizia D'Antoni. Neuroanatomical and clinical correlates of prodromal dementia with Lewy bodies: a systematic literature review of neuroimaging findings. Journal of neurology. vol 272. issue 1. 2024-12-12. PMID:39666108. |
subcortically, atrophy and microstructural damage in the nucleus basalis of meynert were reported, and dopamine transporter uptake was reduced in the basal ganglia. |
2024-12-12 |
2024-12-14 |
Not clear |
| Emily Hueske, Carrie Stine, Tomoko Yoshida, Jill R Crittenden, Akshay Gupta, Joseph C Johnson, Ananya S Achanta, Smitha Bhagavatula, Johnny Loftus, Ara Mahar, Dan Hu, Jesus Azocar, Ryan J Gray, Michael R Bruchas, Ann M Graybie. Developmental and Adult Striatal Patterning of Nociceptin Ligand Marks Striosomal Population With Direct Dopamine Projections. The Journal of comparative neurology. vol 532. issue 12. 2024-12-10. PMID:39656141. |
recent developments in the study of neuropeptide systems have enabled high-resolution investigations of the intersection of neuromodulatory signals with basal ganglia circuitry, identifying the nociceptin/orphanin fq (n/ofq) endogenous opioid peptide system as a prospective regulator of striatal dopamine signaling. |
2024-12-10 |
2024-12-12 |
mouse |
| Muhammad Khalid Iqbal, Bakhtawar Khan, Hifsa, Ge YuXuan, Muhammad Mujahid, Mubin Mustafa Kiyani, Hamid Khan, Shahid Bashi. The Impact of the Blood-Brain Barrier and Its Dysfunction in Parkinson's Disease: Contributions to Pathogenesis and Progression. ACS omega. vol 9. issue 46. 2024-11-25. PMID:39583664. |
parkinson's disease (pd) is a brain disorder in which neuronal cells responsible for the release of dopamine, a neurotransmitter that controls movement, are degenerated or impaired in the substantia nigra and basal ganglia. |
2024-11-25 |
2024-11-27 |
Not clear |
| Yuxin Wang, Zhiqi Jiang, Chunguang Chu, Zhen Zhang, Jiang Wang, Dianyou Li, Naying He, Chris Fietkiewicz, Changsong Zhou, Marcus Kaiser, Xuze Bai, Chencheng Zhang, Chen Li. Push-pull effects of basal ganglia network in Parkinson's disease inferred by functional MRI. NPJ Parkinson's disease. vol 10. issue 1. 2024-11-20. PMID:39567536. |
specifically, increased gabaergic projection into the thalamus from basal ganglia worsens rigidity, while reduced gabaergic projection within the cortex exacerbates bradykinesia, suggesting that the dopamine deficiency induces the chain coupling variations to "push" the network to an abnormal state. |
2024-11-20 |
2024-11-23 |
Not clear |
| Beren Millidge, Yuhang Song, Armin Lak, Mark E Walton, Rafal Bogac. Reward Bases: A simple mechanism for adaptive acquisition of multiple reward types. PLoS computational biology. vol 20. issue 11. 2024-11-19. PMID:39561186. |
we also proposed a possible implementation of the model in the basal ganglia network, and demonstrated how the striatal system can learn values in multiple dimensions, even when dopamine neurons encode mixtures of prediction error from different dimensions. |
2024-11-19 |
2024-11-23 |
Not clear |
| Percy S Agogo-Mawuli, Joseph Mendez, Emily A Oestreich, Dustin E Bosch, David P Siderovsk. Molecular Modeling and In Vitro Functional Analysis of the RGS12 PDZ Domain Variant Associated with High-Penetrance Familial Bipolar Disorder. International journal of molecular sciences. vol 25. issue 21. 2024-11-09. PMID:39518985. |
we previously demonstrated that rgs12 loss removes negative regulation on the kappa opioid receptor, disrupting basal ganglia dopamine homeostasis and dampening responses to dopamine-eliciting psychostimulants. |
2024-11-09 |
2024-11-17 |
Not clear |
| Melissa Serranilla, Jessica C Pressey, Melanie A Woodi. Restoring Compromised Cl The Journal of neuroscience : the official journal of the Society for Neuroscience. 2024-11-05. PMID:39500579. |
early stages of the disease are characterized by the loss of dopamine 2 receptor-expressing msns (d2 msns) followed by degeneration of dopamine 1 receptor-expressing msns (d1 msns), leading to aberrant basal ganglia signaling. |
2024-11-05 |
2024-11-08 |
Not clear |
| Iakovos Lazaridis, Jill R Crittenden, Gun Ahn, Kojiro Hirokane, Ian R Wickersham, Tomoko Yoshida, Ara Mahar, Vasiliki Skara, Johnny H Loftus, Krishna Parvataneni, Konstantinos Meletis, Jonathan T Ting, Emily Hueske, Ayano Matsushima, Ann M Graybie. Striosomes control dopamine via dual pathways paralleling canonical basal ganglia circuits. Current biology : CB. 2024-10-24. PMID:39447573. |
striosomes control dopamine via dual pathways paralleling canonical basal ganglia circuits. |
2024-10-24 |
2024-10-28 |
Not clear |
| Manami Yamaoka, Shuichiro Neshige, Kenta Sasaki, Hirofumi Maruyam. Multiple System Atrophy Masquerading as Drug-Resistant Orthostatic Hypotension. Cureus. vol 16. issue 9. 2024-10-21. PMID:39429427. |
however, a brain magnetic resonance imaging (mri) scan revealed a possible "cross sign" in the pons. subsequent dopamine transporter single-photon emission computed tomography (dat-spect) showed reduced uptake in the basal ganglia. |
2024-10-21 |
2024-10-23 |
Not clear |
| Chelsea M Haakenson, Jacques Balthazart, Jonathan W VanRyzin, Ashley E Marquardt, Sydney E Ashton, Margaret M McCarthy, Gregory F Bal. Neurochemical Characterization of Dopaminoceptive Cells in Song Control Nuclei of Canaries and Their Activation During Song Production: A Multiplex Fluorescent In Situ Hybridization Study. The Journal of comparative neurology. vol 532. issue 10. 2024-10-10. PMID:39387367. |
highly sensitive in situ hybridization procedures (rnascope) were used to quantify the expression of three dopamine receptors (drd1, drd2, and drd3) in two song control nuclei (hvc and the area x of the basal ganglia) that are known to receive dopaminergic inputs and in the periaqueductal gray (pag) of male and female canaries. |
2024-10-10 |
2024-10-16 |
Not clear |
| Cristina Alcacer, Andreas Klaus, Marcelo Mendonça, Sara F Abalde, Maria Angela Cenci, Rui M Cost. Abnormal hyperactivity of specific striatal ensembles encodes distinct dyskinetic behaviors revealed by high-resolution clustering. bioRxiv : the preprint server for biology. 2024-09-24. PMID:39314449. |
l-dopa-induced dyskinesia (lid) is a debilitating complication of dopamine replacement therapy in parkinsońs disease and the most common hyperkinetic disorder of basal ganglia origin. |
2024-09-24 |
2024-09-26 |
mouse |
| Sarah Chevalier, Mélina Decourt, Maureen Francheteau, François Nicol, Anaïs Balbous, Pierre-Olivier Fernagut, Marianne Benoit-Maran. Alpha-synuclein-induced nigrostriatal degeneration and pramipexole treatment disrupt frontostriatal plasticity. NPJ Parkinson's disease. vol 10. issue 1. 2024-09-09. PMID:39251645. |
numerous cellular and molecular adaptations following neurodegeneration or dopamine replacement therapy (drt) have been described in motor networks but little is known regarding associative basal ganglia loops. |
2024-09-09 |
2024-09-13 |
human |
| Alessandro Orsini, Andrea Santangelo, Giorgio Costagliola, Massimo Scacciati, Francesco Massart, Francesca Felicia Operto, Sofia D'Elios, Rita Consolini, Fabrizio De Benedetti, Maria Cristina Maggio, Angela Miniaci, Alessandro Ferretti, Duccio Maria Cordelli, Roberta Battini, Alice Bonuccelli, Salvatore Savasta, Pasquale Parisi, Elisa Fazzi, Martino Ruggieri, Pasquale Striano, Diego Giampietro Peroni, Thomas Foiadell. Management, treatment, and clinical approach of Sydenham's chorea in children: Italian survey on expert-based experience. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society. vol 52. 2024-09-03. PMID:39226700. |
the autoimmune response affecting the basal ganglia, notably against dopamine, underlies the pathophysiology. |
2024-09-03 |
2024-09-06 |
Not clear |
| Christopher R Kelley, Jeffrey L Kauffma. Parkinsonian Tremor as Unstable Feedback in a Physiologically Consistent Control Framework. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. vol PP. 2024-07-17. PMID:39018214. |
parkinson's disease (pd) is characterized by decreased dopamine in the basal ganglia that causes excessive tonic inhibition of the thalamus. |
2024-07-17 |
2024-07-20 |
human |
| Baram Sosis, Jonathan E Rubi. Distinct dopaminergic spike-timing-dependent plasticity rules are suited to different functional roles. bioRxiv : the preprint server for biology. 2024-07-09. PMID:38979377. |
a subset of these models include a third factor, dopamine, which interacts with the timing of pre- and postsynaptic spiking to contribute to plasticity at specific synapses, notably those from cortex to striatum at the input layer of the basal ganglia. |
2024-07-09 |
2024-07-12 |
Not clear |
| Nobuhiko Ohno, Fuyuki Karube, Fumino Fujiyam. Volume Electron Microscopy for Genetically and Molecularly Defined Neural Circuits. Neuroscience research. 2024-06-24. PMID:38914208. |
such approaches advance our understanding of interactions between specific neurons and circuits and may help to elucidate novel aspects of the basal ganglia network involving dopamine neurons. |
2024-06-24 |
2024-06-27 |
Not clear |
| Benedetta Gambosi, Francesco Jamal Sheiban, Marco Biasizzo, Alberto Antonietti, Egidio D'angelo, Alberto Mazzoni, Alessandra Pedrocch. A Model with Dopamine Depletion in Basal Ganglia and Cerebellum Predicts Changes in Thalamocortical Beta Oscillations. International journal of neural systems. 2024-06-17. PMID:38886870. |
a model with dopamine depletion in basal ganglia and cerebellum predicts changes in thalamocortical beta oscillations. |
2024-06-17 |
2024-06-21 |
Not clear |