| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cristina Alcacer, Andreas Klaus, Marcelo Mendonça, Sara F Abalde, Maria Angela Cenci, Rui M Cost. Abnormal hyperactivity of specific striatal ensembles encodes distinct dyskinetic behaviors revealed by high-resolution clustering. bioRxiv : the preprint server for biology. 2024-09-24. PMID:39314449. |
l-dopa-induced dyskinesia (lid) is a debilitating complication of dopamine replacement therapy in parkinsońs disease and the most common hyperkinetic disorder of basal ganglia origin. |
2024-09-24 |
2024-09-26 |
mouse |
| Sarah Chevalier, Mélina Decourt, Maureen Francheteau, François Nicol, Anaïs Balbous, Pierre-Olivier Fernagut, Marianne Benoit-Maran. Alpha-synuclein-induced nigrostriatal degeneration and pramipexole treatment disrupt frontostriatal plasticity. NPJ Parkinson's disease. vol 10. issue 1. 2024-09-09. PMID:39251645. |
numerous cellular and molecular adaptations following neurodegeneration or dopamine replacement therapy (drt) have been described in motor networks but little is known regarding associative basal ganglia loops. |
2024-09-09 |
2024-09-13 |
human |
| Alessandro Orsini, Andrea Santangelo, Giorgio Costagliola, Massimo Scacciati, Francesco Massart, Francesca Felicia Operto, Sofia D'Elios, Rita Consolini, Fabrizio De Benedetti, Maria Cristina Maggio, Angela Miniaci, Alessandro Ferretti, Duccio Maria Cordelli, Roberta Battini, Alice Bonuccelli, Salvatore Savasta, Pasquale Parisi, Elisa Fazzi, Martino Ruggieri, Pasquale Striano, Diego Giampietro Peroni, Thomas Foiadell. Management, treatment, and clinical approach of Sydenham's chorea in children: Italian survey on expert-based experience. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society. vol 52. 2024-09-03. PMID:39226700. |
the autoimmune response affecting the basal ganglia, notably against dopamine, underlies the pathophysiology. |
2024-09-03 |
2024-09-06 |
Not clear |
| Christopher R Kelley, Jeffrey L Kauffma. Parkinsonian Tremor as Unstable Feedback in a Physiologically Consistent Control Framework. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. vol PP. 2024-07-17. PMID:39018214. |
parkinson's disease (pd) is characterized by decreased dopamine in the basal ganglia that causes excessive tonic inhibition of the thalamus. |
2024-07-17 |
2024-07-20 |
human |
| Baram Sosis, Jonathan E Rubi. Distinct dopaminergic spike-timing-dependent plasticity rules are suited to different functional roles. bioRxiv : the preprint server for biology. 2024-07-09. PMID:38979377. |
a subset of these models include a third factor, dopamine, which interacts with the timing of pre- and postsynaptic spiking to contribute to plasticity at specific synapses, notably those from cortex to striatum at the input layer of the basal ganglia. |
2024-07-09 |
2024-07-12 |
Not clear |
| Nobuhiko Ohno, Fuyuki Karube, Fumino Fujiyam. Volume Electron Microscopy for Genetically and Molecularly Defined Neural Circuits. Neuroscience research. 2024-06-24. PMID:38914208. |
such approaches advance our understanding of interactions between specific neurons and circuits and may help to elucidate novel aspects of the basal ganglia network involving dopamine neurons. |
2024-06-24 |
2024-06-27 |
Not clear |
| Benedetta Gambosi, Francesco Jamal Sheiban, Marco Biasizzo, Alberto Antonietti, Egidio D'angelo, Alberto Mazzoni, Alessandra Pedrocch. A Model with Dopamine Depletion in Basal Ganglia and Cerebellum Predicts Changes in Thalamocortical Beta Oscillations. International journal of neural systems. 2024-06-17. PMID:38886870. |
a model with dopamine depletion in basal ganglia and cerebellum predicts changes in thalamocortical beta oscillations. |
2024-06-17 |
2024-06-21 |
Not clear |
| Meghan Van Zandt, Christopher Pittenge. Sexual dimorphism in histamine regulation of striatal dopamine. bioRxiv : the preprint server for biology. 2024-06-03. PMID:38826392. |
dopamine modulation of the basal ganglia is implicated in numerous neuropsychiatric conditions, including ts. |
2024-06-03 |
2024-06-05 |
Not clear |
| Emily Hueske, Carrie Stine, Tomoko Yoshida, Jill R Crittenden, Akshay Gupta, Joseph C Johnson, Ananya S Achanta, Johnny Loftus, Ara Mahar, Dan Hul, Jesus Azocar, Ryan J Gray, Michael R Bruchas, Ann M Graybie. Developmental and adult striatal patterning of nociceptin ligand marks striosomal population with direct dopamine projections. bioRxiv : the preprint server for biology. 2024-05-27. PMID:38798373. |
recent developments in the study of neuropeptide systems have enabled high-resolution investigations of the intersection of neuromodulatory signals with basal ganglia circuitry, identifying the nociceptin/orphanin fq (n/ofq) endogenous opioid peptide system as a prospective regulator of striatal dopamine signaling. |
2024-05-27 |
2024-05-31 |
mouse |
| Yash Wardhan, Sukriti Vishwas, Arumugam Porselvi, Sachin Kumar Singh, Violina Kakot. Exploring the complex interplay between Parkinson's Disease and BAG proteins. Behavioural brain research. 2024-05-20. PMID:38768687. |
parkinsons disease (pd) is a chronic fast growing neurodegenerative disorder of central nervous system (cns) characterized by progressive loss of dopaminergic neurons in the substantia nigra pars compacta (snpc) and formation of lewy bodies (lbs) which causes dopamine deficiency within basal ganglia leading to motor and non-motor manifestation. |
2024-05-20 |
2024-05-27 |
Not clear |
| Maria Mancini, Alessandra Calculli, Deborah Di Martino, Antonio Pisan. Interplay between endocannabinoids and dopamine in the basal ganglia: implications for pain in Parkinson's disease. Journal of anesthesia, analgesia and critical care. vol 4. issue 1. 2024-05-17. PMID:38745258. |
interplay between endocannabinoids and dopamine in the basal ganglia: implications for pain in parkinson's disease. |
2024-05-17 |
2024-05-27 |
Not clear |
| Hyunchan Lee, Hyoung F Kim, Okihide Hikosak. Implication of regional selectivity of dopamine deficits in impaired suppressing of involuntary movements in Parkinson's disease. Neuroscience and biobehavioral reviews. vol 162. 2024-05-17. PMID:38759470. |
we previously found two parallel circuits within the basal ganglia, primarily divided into circuits mediated by the rostral medial part and caudal lateral part of the snc dopamine neurons. |
2024-05-17 |
2024-05-27 |
human |
| Hyunchan Lee, Hyoung F Kim, Okihide Hikosak. Implication of regional selectivity of dopamine deficits in impaired suppressing of involuntary movements in Parkinson's disease. Neuroscience and biobehavioral reviews. vol 162. 2024-05-17. PMID:38759470. |
we have further discovered that the indirect pathway in caudal basal ganglia circuits, facilitated by the caudal lateral part of the snc dopamine neurons, plays a critical role in suppressing unnecessary involuntary movements when animals perform voluntary goal-directed actions. |
2024-05-17 |
2024-05-27 |
human |
| Yilin Tang, Yuting Li, Peiyu Cao, Yingbo Dong, Guoxin Xu, Qi Si, Runda Li, Yuxiu Su. Striatum and globus pallidus structural abnormalities in schizophrenia: A retrospective study of the different stages of the disease. Progress in neuro-psychopharmacology & biological psychiatry. 2024-05-01. PMID:38692473. |
the basal ganglia are important structures for the release of dopamine in the limbic circuits of the midbrain, and the striatum and globus pallidus are the major nuclei of the basal ganglia, and the dysfunction of these regions has been the basis of many models that have attempted to explain the underlying mechanisms of schizophrenia symptoms. |
2024-05-01 |
2024-05-04 |
Not clear |
| Thorsten Rudrof. Decoding Post-Viral Fatigue: The Basal Ganglia's Complex Role in Long-COVID. Neurology international. vol 16. issue 2. 2024-04-26. PMID:38668125. |
mounting evidence from pet, mri, and functional connectivity data reveals basal ganglia disturbances in long-covid exhaustion, including inflammation, metabolic disruption, volume changes, and network alterations focused on striatal dopamine circuitry regulating motivation. |
2024-04-26 |
2024-04-28 |
Not clear |
| Yuhao Wang, Armin Lak, Sanjay G Manohar, Rafal Bogac. Dopamine encoding of novelty facilitates efficient uncertainty-driven exploration. PLoS computational biology. vol 20. issue 4. 2024-04-16. PMID:38626219. |
overall, our results suggest that transient dopamine levels in the basal ganglia that encode novelty could contribute to an uncertainty representation which efficiently drives exploration in reinforcement learning. |
2024-04-16 |
2024-04-19 |
Not clear |
| Maya Molinari, Ori J Lieberman, David Sulzer, Emanuela Santini, Anders Borgkvis. 5-HT1B receptors mediate dopaminergic inhibition of vesicular fusion and GABA release from striatonigral synapses. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38559006. |
the substantia nigra pars reticulata (snr), a crucial basal ganglia output nucleus, contains a dense expression of dopamine d1 receptors (d1rs), along with dendrites belonging to dopaminergic neurons of substantia nigra pars compacta. |
2024-04-01 |
2024-04-04 |
Not clear |
| Tony J Prescott, Fernando M Montes González, Kevin Gurney, Mark D Humphries, Peter Redgrav. Simulated Dopamine Modulation of a Neurorobotic Model of the Basal Ganglia. Biomimetics (Basel, Switzerland). vol 9. issue 3. 2024-03-27. PMID:38534824. |
simulated dopamine modulation of a neurorobotic model of the basal ganglia. |
2024-03-27 |
2024-03-29 |
Not clear |
| Tony J Prescott, Fernando M Montes González, Kevin Gurney, Mark D Humphries, Peter Redgrav. Simulated Dopamine Modulation of a Neurorobotic Model of the Basal Ganglia. Biomimetics (Basel, Switzerland). vol 9. issue 3. 2024-03-27. PMID:38534824. |
the effective operation of basal ganglia circuitry is also known to rely on appropriate levels of the neurotransmitter dopamine. |
2024-03-27 |
2024-03-29 |
Not clear |
| Tony J Prescott, Fernando M Montes González, Kevin Gurney, Mark D Humphries, Peter Redgrav. Simulated Dopamine Modulation of a Neurorobotic Model of the Basal Ganglia. Biomimetics (Basel, Switzerland). vol 9. issue 3. 2024-03-27. PMID:38534824. |
we investigated reducing or increasing the tonic level of simulated dopamine in a prior model of the basal ganglia integrated into a robot control architecture engaged in a foraging task inspired by animal behaviour. |
2024-03-27 |
2024-03-29 |
Not clear |