Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Chang Li, Osama F Elabi, Tim Fieblinger, M Angela Cenc. Structural-functional properties of direct-pathway striatal neurons at early and chronic stages of dopamine denervation. The European journal of neuroscience. 2023-10-25. PMID:37876330. |
the dendritic arbour of striatal projection neurons (spns) is the primary anatomical site where dopamine and glutamate inputs to the basal ganglia functionally interact to control movement. |
2023-10-25 |
2023-11-08 |
mouse |
Shenyu Zhai, Qiaoling Cui, DeNard V Simmons, D James Surmeie. Distributed dopaminergic signaling in the basal ganglia and its relationship to motor disability in Parkinson's disease. Current opinion in neurobiology. vol 83. 2023-10-22. PMID:37866012. |
while our understanding of dopamine (da)'s role in modulating striatal circuitry has deepened in recent years, it also has become clear that it acts in other regions of the basal ganglia to influence movement. |
2023-10-22 |
2023-11-08 |
mouse |
Pol Bech, Sylvain Crochet, Robin Dard, Parviz Ghaderi, Yanqi Liu, Meriam Malekzadeh, Carl C H Petersen, Mauro Pulin, Anthony Renard, Christos Sourmpi. Striatal Dopamine Signals and Reward Learning. Function (Oxford, England). vol 4. issue 6. 2023-10-16. PMID:37841525. |
neuronal circuits of the basal ganglia have been strongly implicated in action selection, as well as the learning and execution of goal-directed behaviors, with accumulating evidence supporting the hypothesis that midbrain dopamine neurons might encode a reward signal useful for learning. |
2023-10-16 |
2023-11-08 |
Not clear |
Kelsey Barcomb, Christopher P For. Alterations in neurotransmitter co-release in Parkinson's disease. Experimental neurology. 2023-10-06. PMID:37802381. |
parkinson's disease is a neurological disorder characterized by degeneration of midbrain dopamine neurons, which results in numerous adaptations in basal ganglia circuits. |
2023-10-06 |
2023-10-15 |
Not clear |
Dimitri Ryczko, Réjean Dubu. Dopamine control of downstream motor centers. Current opinion in neurobiology. vol 83. 2023-09-29. PMID:37774481. |
the role of dopamine in the control of movement is traditionally associated with ascending projections to the basal ganglia. |
2023-09-29 |
2023-10-07 |
Not clear |
Victor Pando-Naude, Tomas Edward Matthews, Andreas Højlund, Sebastian Jakobsen, Karen Østergaard, Erik Johnsen, Eduardo A Garza-Villarreal, Maria A G Witek, Virginia Penhune, Peter Vuus. Dopamine dysregulation in Parkinson's disease flattens the pleasurable urge to move to musical rhythms. The European journal of neuroscience. 2023-09-19. PMID:37724707. |
dopamine in motor and limbic networks is implicated in beat-based timing and music-induced pleasure, suggesting a central role of basal ganglia (bg) dopaminergic systems in plumm. |
2023-09-19 |
2023-10-07 |
human |
Alain Rios, Satoshi Nonomura, Shigeki Kato, Junichi Yoshida, Natsuki Matsushita, Atsushi Nambu, Masahiko Takada, Riichiro Hira, Kazuto Kobayashi, Yutaka Sakai, Minoru Kimura, Yoshikazu Isomur. Reward expectation enhances action-related activity of nigral dopaminergic and two striatal output pathways. Communications biology. vol 6. issue 1. 2023-09-06. PMID:37673949. |
given the classical basal ganglia model wherein dopamine stimulates dspns and suppresses ispns through distinct dopamine receptors, dopamine might not be the primary driver of ispn activity increasing following higher reward expectation. |
2023-09-06 |
2023-10-07 |
rat |
Oleg Tolstenkov, Yana Mikhaleva, Joel C Glove. A miniaturized nigrostriatal-like circuit regulating locomotor performance in a protochordate. Current biology : CB. 2023-08-29. PMID:37643617. |
the circuit is reminiscent of the nigrostriatopallidal system in the vertebrate basal ganglia, in which disinhibitory circuits release specific movements under the modulatory control of dopamine. |
2023-08-29 |
2023-09-07 |
Not clear |
Véronique Coizet, Racha Al Tannir, Arnaud Pautrat, Paul G Overto. Separation of Channels Subserving Approach and Avoidance/Escape at the Level of the Basal Ganglia and Related Brainstem Structures. Current neuropharmacology. 2023-08-18. PMID:37594168. |
this function relies on afferents targeting the main input structures of the basal ganglia, entering bids for action selection at the level of the striatum or sig- nals for behavioral interruption at the level of the subthalamic nucleus, with behavioral reselection facilitated by dopamine signaling. |
2023-08-18 |
2023-09-07 |
Not clear |
Emil Wärnberg, Arvind Kuma. Feasibility of dopamine as a vector-valued feedback signal in the basal ganglia. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 32. 2023-08-01. PMID:37527344. |
feasibility of dopamine as a vector-valued feedback signal in the basal ganglia. |
2023-08-01 |
2023-08-14 |
Not clear |
Rupsha Mondal, Chayan Banerjee, Sumangal Nandy, Moumita Roy, Joy Chakrabort. Calcineurin inhibition protects against dopamine toxicity and attenuates behavioral decline in a Parkinson's disease model. Cell & bioscience. vol 13. issue 1. 2023-08-01. PMID:37528492. |
this leads to depleted dopamine (da) content at striatum, thus affecting the fine tuning of basal ganglia. |
2023-08-01 |
2023-08-14 |
Not clear |
Michael B Prit. Nuclei and tracts in the epithalamus of crocodiles. The Journal of comparative neurology. 2023-07-29. PMID:37507852. |
the medial component is related to the limbic system and serotonergic raphe, while the lateral nucleus is more interconnected with the basal ganglia and midbrain dopamine systems. |
2023-07-29 |
2023-08-14 |
Not clear |
Chayaporn Reakkamnuan, Dania Cheaha, Nifareeda Samerphop, Jakkrit Nukitram, Ekkasit Kumarnsi. Differential local field potential oscillations in the dorsal striatum and locomotor activity induced by morphine and haloperidol in mice. Acta neurobiologiae experimentalis. vol 83. issue 2. 2023-07-26. PMID:37493531. |
dopamine (da) depletion in the dorsal striatum underlies symptoms of basal ganglia pathologies, including parkinson's disease (pd). |
2023-07-26 |
2023-08-14 |
mouse |
Charles Ducrot, Gregory de Carvalho, Benoit Delignat-Lavaud, Constantin V L Delmas, Priyabrata Halder, Nicolas Giguère, Consiglia Pacelli, Sriparna Mukherjee, Marie-Josée Bourque, Martin Parent, LuLu Y Chen, Louis-Eric Trudea. Conditional deletion of neurexins dysregulates neurotransmission from dopamine neurons. eLife. vol 12. 2023-07-06. PMID:37409563. |
midbrain dopamine (da) neurons are key regulators of basal ganglia functions. |
2023-07-06 |
2023-08-14 |
mouse |
Ilene Trinh, Angeni Muralidhar, Justin Yang, Nicolás Phielip. Quantified Striatal Dopaminergic Denervation as Predictor for Motor Outcomes in Parkinson's Disease. Movement disorders clinical practice. vol 10. issue 6. 2023-06-19. PMID:37332639. |
a hallmark of parkinson's disease (pd) is progressive loss of dopamine terminals in the basal ganglia, with clinical symptoms including motor and non-motor manifestations such as bradykinesia, rigidity, and cognitive impairment. |
2023-06-19 |
2023-08-14 |
Not clear |
Cláudia Raquel Marques, Miguel de Almeida Fuzeta, Raquel Medina Dos Santos Cunha, Joana Pereira-Sousa, Deolinda Silva, Jonas Campos, Andreia Teixeira-Castro, Rui Amandi Sousa, Ana Fernandes-Platzgummer, Cláudia L da Silva, António José Salgad. Neurodifferentiation and Neuroprotection Potential of Mesenchymal Stromal Cell-Derived Secretome Produced in Different Dynamic Systems. Biomedicines. vol 11. issue 5. 2023-05-27. PMID:37238911. |
parkinson's disease (pd) is the second most common neurodegenerative disorder and is characterized by the degeneration of the dopamine (da) neurons in the substantia nigra pars compacta, leading to a loss of da in the basal ganglia. |
2023-05-27 |
2023-08-14 |
human |
M T Herrero, J E Yuste, L Cuenca-Bermejo, P Almela, L Arenas-Betancur, V De Pablos, A Gonzalez-Cuello, E Del Bel, J Navarro-Zaragoza, E Fernández-Villalb. 7-Nitroindazole reduces L-DOPA-induced dyskinesias in non-human Parkinsonian primate. Open biology. vol 13. issue 5. 2023-05-16. PMID:37192671. |
nitric oxide (no) plays a pivotal role in integrating dopamine transmission in the basal ganglia and has been implicated in the pathogenesis of parkinson disease (pd). |
2023-05-16 |
2023-08-14 |
monkey |
Julia Henkel, Christian Hartmann, Valentina Niccolai, Ruben van de Vijver, Alfons Schnitzler, Katja Biermann-Rube. Reduced syntactic recursion in spontaneous speech of Parkinson's disease patients. Acta psychologica. vol 236. 2023-05-06. PMID:37148642. |
our results suggest a contribution of the basal ganglia to language processing, such as syntactic composition, which, however, does not seem to be dopamine dependent. |
2023-05-06 |
2023-08-14 |
Not clear |
Andrea Ortone, Alberto Arturo Vergani, Mahboubeh Ahmadipour, Riccardo Mannella, Alberto Mazzon. Dopamine depletion leads to pathological synchronization of distinct basal ganglia loops in the beta band. PLoS computational biology. vol 19. issue 4. 2023-04-27. PMID:37104542. |
dopamine depletion leads to pathological synchronization of distinct basal ganglia loops in the beta band. |
2023-04-27 |
2023-08-14 |
human |
Andrea Ortone, Alberto Arturo Vergani, Mahboubeh Ahmadipour, Riccardo Mannella, Alberto Mazzon. Dopamine depletion leads to pathological synchronization of distinct basal ganglia loops in the beta band. PLoS computational biology. vol 19. issue 4. 2023-04-27. PMID:37104542. |
motor symptoms of parkinson's disease (pd) are associated with dopamine deficits and pathological oscillation of basal ganglia (bg) neurons in the β range ([12-30] hz). |
2023-04-27 |
2023-08-14 |
human |