| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Björn Falkenburger, Theodoros Kalliakoudas, Heinz Reichman. Adaptive changes in striatal projection neurons explain the long duration response and the emergence of dyskinesias in patients with Parkinson's disease. Journal of neural transmission (Vienna, Austria : 1996). 2022-05-10. PMID:35538324. |
we hypothesize that these clinical observations can be explained by homeostatic plasticity in the basal ganglia, suggesting that plastic changes in response to chronic dopamine depletion and substitution need to be incorporated into models of basal ganglia function. |
2022-05-10 |
2023-08-13 |
Not clear |
| Md Mominur Rahman, Sadia Afsana Mim, Md Rezaul Islam, Nasrin Sultana, Muniruddin Ahmed, Mohammad Amjad Kama. Role of G-proteins and GPCR-Mediated Signalling in Neuropathophysiology. CNS & neurological disorders drug targets. 2022-05-04. PMID:35507780. |
gpr52, gpr6, and gpr8 are recognised as orphan gpcrs, co-exist either with both the dopamine d2 and d1 receptors in neurons of the basal ganglia or with the dopamine d2 receptor alone, and recommend that between these orphan receptors, gpr52 has the maximum potential of being a therapeutic psychiatric receptor. |
2022-05-04 |
2023-08-13 |
Not clear |
| Isabelle Waku, Adriano E Reimer, Amanda R de Oliveir. Effects of Immediate Aversive Stimulation on Haloperidol-Induced Catalepsy in Rats. Frontiers in behavioral neuroscience. vol 16. 2022-04-28. PMID:35481243. |
in pd, the motor impairments are due to difficulties in selecting and executing motor actions, associated with dopamine loss in basal ganglia and cortical targets. |
2022-04-28 |
2023-08-13 |
rat |
| Sajeda G Matar, Zeinab S El-Nahas, Hala Aladwan, Menna Hasanin, Sarah M Elsayed, Anas Z Nourelden, Amira Y Benmelouka, Khaled M Raga. Restless Leg Syndrome in Hemodialysis Patients: A Narrative Review. The neurologist. 2022-04-20. PMID:35442939. |
furthermore, both pharmacological and neuroimaging studies demonstrated dopamine deficiency and dopamine receptors decrease in basal ganglia during rls. |
2022-04-20 |
2023-08-13 |
Not clear |
| Radwa Khalil, Ahmed A Moustaf. A neurocomputational model of creative processes. Neuroscience and biobehavioral reviews. 2022-04-17. PMID:35430189. |
our neurocomputational perspective is based on three creative processes based on novelty seeking, subserved by the prefrontal cortex, hippocampus, cerebellum, basal ganglia, and dopamine. |
2022-04-17 |
2023-08-13 |
Not clear |
| Xiaodong Wang, Yinhao Wang, Jian Chen, Juan Li, Yang Liu, Wei Che. Aerobic exercise improves motor function and striatal MSNs-Erk/MAPK signaling in mice with 6-OHDA-induced Parkinson's disease. Experimental brain research. 2022-04-06. PMID:35384454. |
in parkinson's disease (pd) state, with progressive loss of dopaminergic neurons in the substantia nigra, the striatal dopamine (da) and glutamate (glu) levels change, resulting in dysfunction of basal ganglia motor regulation. |
2022-04-06 |
2023-08-13 |
mouse |
| Ashley C Parr, Finnegan Calabro, Brenden Tervo-Clemmens, Bart Larsen, Will Foran, Beatriz Lun. Contributions of dopamine-related basal ganglia neurophysiology to the developmental effects of incentives on inhibitory control. Developmental cognitive neuroscience. vol 54. 2022-03-28. PMID:35344773. |
our results provide novel evidence that basal ganglia neurophysiology supports developmental effects of rewards on cognition, which can inform neurodevelopmental models of the role of dopamine in reward processing during adolescence. |
2022-03-28 |
2023-08-13 |
Not clear |
| John G Mikhael, HyungGoo R Kim, Naoshige Uchida, Samuel J Gershma. The role of state uncertainty in the dynamics of dopamine. Current biology : CB. 2022-02-03. PMID:35114098. |
reinforcement learning models of the basal ganglia map the phasic dopamine signal to reward prediction errors (rpes). |
2022-02-03 |
2023-08-13 |
mouse |
| Fernando Caravaggio, Alexander J Barnett, Shinichiro Nakajima, Yusuke Iwata, Julia Kim, Carol Borlido, Wanna Mar, Philip Gerretsen, Gary Remington, Ariel Graff-Guerrer. The effects of acute dopamine depletion on resting-state functional connectivity in healthy humans. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 57. 2022-01-29. PMID:35091322. |
we examined how ampt-induced dopamine depletion alters resting-state functional connectivity of the basal ganglia, and canonical resting-state networks, in healthy humans. |
2022-01-29 |
2023-08-13 |
human |
| Fernando Caravaggio, Alexander J Barnett, Shinichiro Nakajima, Yusuke Iwata, Julia Kim, Carol Borlido, Wanna Mar, Philip Gerretsen, Gary Remington, Ariel Graff-Guerrer. The effects of acute dopamine depletion on resting-state functional connectivity in healthy humans. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 57. 2022-01-29. PMID:35091322. |
these findings help us to better understand the role of dopamine in basal ganglia function and may help us better understand neuropsychiatric diseases where abnormal dopamine levels are observed. |
2022-01-29 |
2023-08-13 |
human |
| Sandeep Sathyanandan Nair, Vignayanandam Ravindernath Muddapu, V Srinivasa Chakravarth. A Multiscale, Systems-Level, Neuropharmacological Model of Cortico-Basal Ganglia System for Arm Reaching Under Normal, Parkinsonian, and Levodopa Medication Conditions. Frontiers in computational neuroscience. vol 15. 2022-01-20. PMID:35046787. |
there is a modelling tradition that links dopamine to reward and uses reinforcement learning (rl) concepts to model the basal ganglia. |
2022-01-20 |
2023-08-13 |
Not clear |
| Molly Brady, Anna Beltramini, Gavin Vaughan, Allison R Bechar. Benefits of a ketogenic diet on repetitive motor behavior in mice. Behavioural brain research. 2022-01-17. PMID:35038463. |
future research will explore the relationship between kd and dopamine within basal ganglia nuclei that may be influencing the benefits of kd on repetitive behavior. |
2022-01-17 |
2023-08-13 |
mouse |
| Per A Al. The Dopamine System and Automatization of Movement Sequences: A Review With Relevance for Speech and Stuttering. Frontiers in human neuroscience. vol 15. 2021-12-20. PMID:34924974. |
one of the core functions of dopamine involves the basal ganglia and the learning and execution of automatized sequences of movements. |
2021-12-20 |
2023-08-13 |
human |
| Per A Al. The Dopamine System and Automatization of Movement Sequences: A Review With Relevance for Speech and Stuttering. Frontiers in human neuroscience. vol 15. 2021-12-20. PMID:34924974. |
speech is one of the most complex and highly automatized sequential motor behaviors, though the exact roles that the basal ganglia and dopamine play in speech have been difficult to determine. |
2021-12-20 |
2023-08-13 |
human |
| Per A Al. The Dopamine System and Automatization of Movement Sequences: A Review With Relevance for Speech and Stuttering. Frontiers in human neuroscience. vol 15. 2021-12-20. PMID:34924974. |
stuttering is a speech disorder that has been hypothesized to be related to the functions of the basal ganglia and dopamine. |
2021-12-20 |
2023-08-13 |
human |
| Hernán Cortés, Octavio D Reyes-Hernández, Maykel Gonzalez-Torres, Pablo A Vizcaino-Dorado, Maria Luisa Del Prado-Audelo, Sergio Alcalá-Alcalá, Javad Sharifi-Rad, Gabriela Figueroa-González, Manuel González-Del Carmen, Benjamí N Florán, Gerardo Leyva-Góme. Curcumin for parkinson´s disease: potential therapeutic effects, molecular mechanisms, and nanoformulations to enhance its efficacy. Cellular and molecular biology (Noisy-le-Grand, France). vol 67. issue 1. 2021-11-25. PMID:34817361. |
this neuronal loss causes the dopamine deficiency that leads to a series of functional changes within the basal ganglia, producing motor control abnormalities. |
2021-11-25 |
2023-08-13 |
Not clear |
| Laura Colautti, Paola Iannello, Maria Caterina Silveri, Alessandro Antoniett. Decision making in Parkinson's disease: An analysis of the studies using the Iowa Gambling Task. The European journal of neuroscience. vol 54. issue 10. 2021-11-24. PMID:34655122. |
the possible role played by dopamine medications in decision making under uncertain conditions, affecting basal ganglia and structures involved in the limbic loop, was discussed. |
2021-11-24 |
2023-08-13 |
Not clear |
| Eleanor Porter, Andreas-Antonios Roussakis, Nicholas P Lao-Kaim, Paola Piccin. Multimodal dopamine transporter (DAT) imaging and magnetic resonance imaging (MRI) to characterise early Parkinson's disease. Parkinsonism & related disorders. vol 79. 2021-11-15. PMID:32861103. |
currently, in early idiopathic pd, dopamine transporter (dat)-specific imaging assesses the extent of striatal dopaminergic deficits, and conventional magnetic resonance imaging (mri) of the brain excludes the presence of significant ischaemic load in the basal ganglia as well as signs indicative of other forms of parkinsonism. |
2021-11-15 |
2023-08-13 |
Not clear |
| Florence Véronneau-Veilleux, Philippe Robaey, Mauro Ursino, Fahima Nekk. An integrative model of Parkinson's disease treatment including levodopa pharmacokinetics, dopamine kinetics, basal ganglia neurotransmission and motor action throughout disease progression. Journal of pharmacokinetics and pharmacodynamics. vol 48. issue 1. 2021-11-08. PMID:33084988. |
an integrative model of parkinson's disease treatment including levodopa pharmacokinetics, dopamine kinetics, basal ganglia neurotransmission and motor action throughout disease progression. |
2021-11-08 |
2023-08-13 |
human |
| Florence Véronneau-Veilleux, Philippe Robaey, Mauro Ursino, Fahima Nekk. An integrative model of Parkinson's disease treatment including levodopa pharmacokinetics, dopamine kinetics, basal ganglia neurotransmission and motor action throughout disease progression. Journal of pharmacokinetics and pharmacodynamics. vol 48. issue 1. 2021-11-08. PMID:33084988. |
we combined a pharmacokinetic model of levodopa to a model of dopamine's kinetics and a neurocomputational model of basal ganglia. |
2021-11-08 |
2023-08-13 |
human |