| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michele A Kliem, Jean-Francois Pare, Zafar U Khan, Thomas Wichmann, Yoland Smit. Comparative Ultrastructural Analysis of D1 and D5 Dopamine Receptor Distribution in the Substantia Nigra and Globus Pallidus of Monkeys. Advances in behavioral biology. vol 58. 2021-10-20. PMID:19750130. |
in order to further characterize the potential targets whereby dopamine could mediate its effects in basal ganglia output nuclei, we undertook a comparative electron microscopic analysis of d1 and d5 receptors immunoreactivity in the gpi and snr of rhesus monkeys. |
2021-10-20 |
2023-08-12 |
monkey |
| Michele A Kliem, Jean-Francois Pare, Zafar U Khan, Thomas Wichmann, Yoland Smit. Comparative Ultrastructural Analysis of D1 and D5 Dopamine Receptor Distribution in the Substantia Nigra and Globus Pallidus of Monkeys. Advances in behavioral biology. vol 58. 2021-10-20. PMID:19750130. |
these findings provide evidence for the existence of extrastriatal pre- and post-synaptic targets through which dopamine and drugs acting at d1-like receptors may regulate basal ganglia outflow and possibly exert some of their anti-parkinsonian effects. |
2021-10-20 |
2023-08-12 |
monkey |
| Reka Natarajan, Bryan K Yamamot. The Basal Ganglia as a Substrate for the Multiple Actions of Amphetamines. Basal ganglia. vol 1. issue 2. 2021-10-20. PMID:21804952. |
acute and chronic doses of amphetamines affect dopamine (da) neurotransmission in the basal ganglia. |
2021-10-20 |
2023-08-12 |
Not clear |
| Li-Xuan Li, Yu-Lan Li, Jin-Tao Wu, Ji-Zhou Song, Xiao-Ming L. Glutamatergic Neurons in the Caudal Zona Incerta Regulate Parkinsonian Motor Symptoms in Mice. Neuroscience bulletin. 2021-10-11. PMID:34633650. |
in recent years, it has been recognized that neurotransmitters other than dopamine and neuronal systems outside the basal ganglia are also related to pd pathogenesis. |
2021-10-11 |
2023-08-13 |
mouse |
| Jonathan Sackner-Bernstei. Estimates of Intracellular Dopamine in Parkinson's Disease: A Systematic Review and Meta-Analysis. Journal of Parkinson's disease. vol 11. issue 3. 2021-10-09. PMID:34024786. |
the hallmark of parkinson's disease is depletion of dopamine in the basal ganglia. |
2021-10-09 |
2023-08-13 |
Not clear |
| Lauren Malave, Dustin R Zuelke, Santiago Uribe-Cano, Lev Starikov, Heike Rebholz, Eitan Friedman, Chuan Qin, Qin Li, Erwan Bezard, Andreas H Kottman. Dopaminergic co-transmission with sonic hedgehog inhibits abnormal involuntary movements in models of Parkinson's disease and L-Dopa induced dyskinesia. Communications biology. vol 4. issue 1. 2021-10-09. PMID:34552196. |
here we report that diminished sonic hedgehog (shh) signaling in the basal ganglia caused by the degeneration of midbrain dopamine neurons facilitates the formation and expression of lid. |
2021-10-09 |
2023-08-13 |
mouse |
| Amber M Muehlmann, Sebastian Maletz, Michael A King, Mark H Lewi. Pharmacological targeting of striatal indirect pathway neurons improves subthalamic nucleus dysfunction and reduces repetitive behaviors in C58 mice. Behavioural brain research. vol 391. 2021-10-05. PMID:32461129. |
in the current study, we tested whether a drug cocktail (dopamine d2 receptor antagonist + adenosine a2a receptor agonist + glutamate mglu5 positive allosteric modulator) designed to activate the indirect basal ganglia pathway would reduce repetitive behavior in c58 mice after both acute and sub-chronic administration. |
2021-10-05 |
2023-08-13 |
mouse |
| Alexander Woolrych, Nicolas Vautrelle, John N J Reynolds, Louise C Parr-Brownli. Throwing open the doors of perception: The role of dopamine in visual processing. The European journal of neuroscience. vol 54. issue 6. 2021-09-24. PMID:34340265. |
however, such signals primarily originate in cortical and basal ganglia circuits, and evidence of direct signalling from midbrain dopamine neurons to superior colliculus is lacking. |
2021-09-24 |
2023-08-13 |
Not clear |
| Atul Goel, Ramkumar Sugumaran, Sunil K Naraya. Zonisamide in Parkinson's disease: a current update. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 42. issue 10. 2021-09-17. PMID:34448999. |
parkinson's disease (pd) is a progressive neurodegenerative disease due to the depletion of the neurotransmitter dopamine in basal ganglia. |
2021-09-17 |
2023-08-13 |
Not clear |
| Maria A Briscione, Ashok R Dinasarapu, Pritha Bagchi, Yuping Donsante, Kaitlyn M Roman, Anthony M Downs, Xueliang Fan, Jessica Hoehner, H A Jinnah, Ellen J Hes. Differential expression of striatal proteins in a mouse model of DOPA-responsive dystonia reveals shared mechanisms among dystonic disorders. Molecular genetics and metabolism. vol 133. issue 4. 2021-09-16. PMID:34092491. |
the inherited metabolic disorder dopa-responsive dystonia is considered a prototype for understanding basal ganglia dysfunction in dystonia because it is caused by mutations in genes necessary for the synthesis of the neurotransmitter dopamine, which mediates the activity of the basal ganglia. |
2021-09-16 |
2023-08-13 |
mouse |
| Shakya Bhattacharjee, Muhammad Noushad, Martin Sadle. Early Onset Degenerative Parkinsonism - Consider SPG7 Mutation. Neurology India. vol 69. issue 4. 2021-09-14. PMID:34507444. |
however, the dopamine transporter scan showed abnormal tracer uptake in both basal ganglia, suggestive of degenerative parkinsonism. |
2021-09-14 |
2023-08-13 |
Not clear |
| Peter A Kempster, Laura Perju-Dumbrav. The Thermodynamic Consequences of Parkinson's Disease. Frontiers in neurology. vol 12. 2021-09-14. PMID:34512508. |
that the dopaminergic deficit of pd creates a problem with energy efficiency highlights the role played by the basal ganglia, and by dopamine, in thermodynamic governance. |
2021-09-14 |
2023-08-13 |
Not clear |
| Bryant J Jongkee. Baseline-dependent effect of dopamine's precursor L-tyrosine on working memory gating but not updating. Cognitive, affective & behavioral neuroscience. vol 20. issue 3. 2021-08-30. PMID:32133585. |
this balance is controlled by an input-gating mechanism implemented by dopamine in the basal ganglia. |
2021-08-30 |
2023-08-13 |
human |
| Andrew Schneider, Adam T Sari, Hasan Alhaddad, Youssef Sar. Overview of Therapeutic Drugs and Methods for the Treatment of Parkinson's Disease. CNS & neurological disorders drug targets. vol 19. issue 3. 2021-08-30. PMID:32448109. |
over the past decades, most of the medications for the treatment of pd patients have been used to modulate dopamine concentrations in the basal ganglia. |
2021-08-30 |
2023-08-13 |
Not clear |
| Vishal Rawji, Lorenzo Rocchi, Tom Foltynie, John C Rothwell, Marjan Jahanshah. Ropinirole, a dopamine agonist with high D Neuropharmacology. vol 179. 2021-08-27. PMID:32827517. |
dopamine has been posed as a candidate mediator of response inhibition due to its role in functioning of the basal ganglia and the observation that patients with parkinson's disease on dopamine agonists develop impulse control disorders. |
2021-08-27 |
2023-08-13 |
human |
| Adjia Hamadjida, Stephen G Nuara, Imane Frouni, Cynthia Kwan, Dominique Bédard, Jim C Gourdon, Philippe Huo. Monoamine oxidase A inhibition as monotherapy reverses parkinsonism in the MPTP-lesioned marmoset. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 11. 2021-08-26. PMID:32601846. |
here, we explore the anti-parkinsonian effect of mao type a (mao-a) inhibition as monotherapy, as the enzyme mao-a is also encountered within the primate and human basal ganglia, where it metabolises dopamine, albeit to a lesser extent than mao-b. |
2021-08-26 |
2023-08-13 |
human |
| Yuksel Caki. Computational neuronal correlation with enhanced synchronized activity in the basal ganglia and the slowing of thalamic theta and alpha rhythms in Parkinson's disease. The European journal of neuroscience. vol 54. issue 3. 2021-08-23. PMID:34192822. |
the aim of this work is computationally to correlate the synchronized neuronal activity of basal ganglia and slowing in theta and alpha rhythms in electroencephalogram (eeg) signal in thalamic region in case of dopamine depletion and decrease of synaptic connections. |
2021-08-23 |
2023-08-13 |
Not clear |
| Yuksel Caki. Computational neuronal correlation with enhanced synchronized activity in the basal ganglia and the slowing of thalamic theta and alpha rhythms in Parkinson's disease. The European journal of neuroscience. vol 54. issue 3. 2021-08-23. PMID:34192822. |
depending on the decrease of synaptic connections and dopamine level, the synchronization among basal ganglia neuron populations is investigated. |
2021-08-23 |
2023-08-13 |
Not clear |
| Elisa Frisaldi, Aziz Shaibani, Fabrizio Benedett. Understanding the mechanisms of placebo and nocebo effects. Swiss medical weekly. vol 150. 2021-08-18. PMID:32920787. |
in these medical conditions the neural networks involved have indeed been identified: that is, opioid, cannabinoid, cholecystokinin, cyclooxygenase, and dopamine modulatory networks in pain; and part of the basal ganglia circuitry in parkinson’s disease. |
2021-08-18 |
2023-08-13 |
human |
| Florence Véronneau-Veilleux, Mauro Ursino, Philippe Robaey, Daniel Lévesque, Fahima Nekk. Nonlinear pharmacodynamics of levodopa through Parkinson's disease progression. Chaos (Woodbury, N.Y.). vol 30. issue 9. 2021-08-18. PMID:33003902. |
using a holistic approach, a pharmacokinetic model of levodopa was combined to a dopamine dynamics and a neurocomputational model of basal ganglia. |
2021-08-18 |
2023-08-13 |
Not clear |