| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei-Wei Bao, Wei Xu, Gao-Jie Pan, Tian-Xiao Wang, Yuan Han, Wei-Min Qu, Wen-Xian Li, Zhi-Li Huan. Nucleus accumbens neurons expressing dopamine D1 receptors modulate states of consciousness in sevoflurane anesthesia. Current biology : CB. vol 31. issue 9. 2021-11-04. PMID:33705720. |
here, we found that population activities of neurons expressing dopamine d1 receptor (d1r) in the nucleus accumbens (nac), a critical interface between the basal ganglia and limbic system, began to decrease before sevoflurane-induced loc and gradually returned after recovery of consciousness (roc). |
2021-11-04 |
2023-08-13 |
Not clear |
| Stephen E Nadea. Basal Ganglia and Thalamic Contributions to Language Function: Insights from A Parallel Distributed Processing Perspective. Neuropsychology review. vol 31. issue 3. 2021-10-28. PMID:33512608. |
the pdp lens and an understanding of the attractor trench dynamics of the basal ganglia provide a natural explanation for the peculiar dysfunctions of parkinson's disease and the mechanisms by which dopamine deficiency is causal. |
2021-10-28 |
2023-08-13 |
Not clear |
| Alicia M P Warnecke, Moon S Kang, Michael W Jakowec, Daryl L Davie. The macrocyclic lactones ivermectin and moxidectin show differential effects on rotational behavior in the 6-hydroxydopamine mouse model of Parkinson's disease. Behavioural brain research. vol 393. 2021-10-25. PMID:32668263. |
parkinson's disease (pd) is a common neurodegenerative disease characterized by motor and cognitive deficits, the result of dopamine (da)-depletion within the basal ganglia. |
2021-10-25 |
2023-08-13 |
mouse |
| Seth Herd, Kai Krueger, Ananta Nair, Jessica Mollick, Randall O'Reill. Neural Mechanisms of Human Decision-Making. Cognitive, affective & behavioral neuroscience. vol 21. issue 1. 2021-10-25. PMID:33409958. |
the reward-prediction system acts as a critic​ to determine the value of the outcome relative to expectations and produce dopamine as a training signal for cortex and basal ganglia. |
2021-10-25 |
2023-08-13 |
human |
| Ariana Z Turk, Mahsa Lotfi Marchoubeh, Ingrid Fritsch, Gerald A Maguire, Shahriar SheikhBahae. Dopamine, vocalization, and astrocytes. Brain and language. vol 219. 2021-10-25. PMID:34098250. |
dopamine, the main catecholamine neurotransmitter in the brain, is predominately produced in the basal ganglia and released to various brain regions including the frontal cortex, midbrain and brainstem. |
2021-10-25 |
2023-08-13 |
Not clear |
| Jonathan W Dickerson, P Jeffrey Con. Therapeutic potential of targeting metabotropic glutamate receptors for Parkinson's disease. Neurodegenerative disease management. vol 2. issue 2. 2021-10-21. PMID:23526920. |
recent breakthroughs are providing the first major advances in the development of fundamentally new pharmacological strategies for the treatment of pd that do not rely on dopamine replacement strategies, but rather aim to reduce the overactive indirect pathway within the basal ganglia. |
2021-10-21 |
2023-08-12 |
Not clear |
| Michele A Kliem, Jean-Francois Pare, Zafar U Khan, Thomas Wichmann, Yoland Smit. Comparative Ultrastructural Analysis of D1 and D5 Dopamine Receptor Distribution in the Substantia Nigra and Globus Pallidus of Monkeys. Advances in behavioral biology. vol 58. 2021-10-20. PMID:19750130. |
in order to further characterize the potential targets whereby dopamine could mediate its effects in basal ganglia output nuclei, we undertook a comparative electron microscopic analysis of d1 and d5 receptors immunoreactivity in the gpi and snr of rhesus monkeys. |
2021-10-20 |
2023-08-12 |
monkey |
| Michele A Kliem, Jean-Francois Pare, Zafar U Khan, Thomas Wichmann, Yoland Smit. Comparative Ultrastructural Analysis of D1 and D5 Dopamine Receptor Distribution in the Substantia Nigra and Globus Pallidus of Monkeys. Advances in behavioral biology. vol 58. 2021-10-20. PMID:19750130. |
these findings provide evidence for the existence of extrastriatal pre- and post-synaptic targets through which dopamine and drugs acting at d1-like receptors may regulate basal ganglia outflow and possibly exert some of their anti-parkinsonian effects. |
2021-10-20 |
2023-08-12 |
monkey |
| Reka Natarajan, Bryan K Yamamot. The Basal Ganglia as a Substrate for the Multiple Actions of Amphetamines. Basal ganglia. vol 1. issue 2. 2021-10-20. PMID:21804952. |
acute and chronic doses of amphetamines affect dopamine (da) neurotransmission in the basal ganglia. |
2021-10-20 |
2023-08-12 |
Not clear |
| Li-Xuan Li, Yu-Lan Li, Jin-Tao Wu, Ji-Zhou Song, Xiao-Ming L. Glutamatergic Neurons in the Caudal Zona Incerta Regulate Parkinsonian Motor Symptoms in Mice. Neuroscience bulletin. 2021-10-11. PMID:34633650. |
in recent years, it has been recognized that neurotransmitters other than dopamine and neuronal systems outside the basal ganglia are also related to pd pathogenesis. |
2021-10-11 |
2023-08-13 |
mouse |
| Jonathan Sackner-Bernstei. Estimates of Intracellular Dopamine in Parkinson's Disease: A Systematic Review and Meta-Analysis. Journal of Parkinson's disease. vol 11. issue 3. 2021-10-09. PMID:34024786. |
the hallmark of parkinson's disease is depletion of dopamine in the basal ganglia. |
2021-10-09 |
2023-08-13 |
Not clear |
| Lauren Malave, Dustin R Zuelke, Santiago Uribe-Cano, Lev Starikov, Heike Rebholz, Eitan Friedman, Chuan Qin, Qin Li, Erwan Bezard, Andreas H Kottman. Dopaminergic co-transmission with sonic hedgehog inhibits abnormal involuntary movements in models of Parkinson's disease and L-Dopa induced dyskinesia. Communications biology. vol 4. issue 1. 2021-10-09. PMID:34552196. |
here we report that diminished sonic hedgehog (shh) signaling in the basal ganglia caused by the degeneration of midbrain dopamine neurons facilitates the formation and expression of lid. |
2021-10-09 |
2023-08-13 |
mouse |
| Amber M Muehlmann, Sebastian Maletz, Michael A King, Mark H Lewi. Pharmacological targeting of striatal indirect pathway neurons improves subthalamic nucleus dysfunction and reduces repetitive behaviors in C58 mice. Behavioural brain research. vol 391. 2021-10-05. PMID:32461129. |
in the current study, we tested whether a drug cocktail (dopamine d2 receptor antagonist + adenosine a2a receptor agonist + glutamate mglu5 positive allosteric modulator) designed to activate the indirect basal ganglia pathway would reduce repetitive behavior in c58 mice after both acute and sub-chronic administration. |
2021-10-05 |
2023-08-13 |
mouse |
| Alexander Woolrych, Nicolas Vautrelle, John N J Reynolds, Louise C Parr-Brownli. Throwing open the doors of perception: The role of dopamine in visual processing. The European journal of neuroscience. vol 54. issue 6. 2021-09-24. PMID:34340265. |
however, such signals primarily originate in cortical and basal ganglia circuits, and evidence of direct signalling from midbrain dopamine neurons to superior colliculus is lacking. |
2021-09-24 |
2023-08-13 |
Not clear |
| Atul Goel, Ramkumar Sugumaran, Sunil K Naraya. Zonisamide in Parkinson's disease: a current update. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 42. issue 10. 2021-09-17. PMID:34448999. |
parkinson's disease (pd) is a progressive neurodegenerative disease due to the depletion of the neurotransmitter dopamine in basal ganglia. |
2021-09-17 |
2023-08-13 |
Not clear |
| Maria A Briscione, Ashok R Dinasarapu, Pritha Bagchi, Yuping Donsante, Kaitlyn M Roman, Anthony M Downs, Xueliang Fan, Jessica Hoehner, H A Jinnah, Ellen J Hes. Differential expression of striatal proteins in a mouse model of DOPA-responsive dystonia reveals shared mechanisms among dystonic disorders. Molecular genetics and metabolism. vol 133. issue 4. 2021-09-16. PMID:34092491. |
the inherited metabolic disorder dopa-responsive dystonia is considered a prototype for understanding basal ganglia dysfunction in dystonia because it is caused by mutations in genes necessary for the synthesis of the neurotransmitter dopamine, which mediates the activity of the basal ganglia. |
2021-09-16 |
2023-08-13 |
mouse |
| Shakya Bhattacharjee, Muhammad Noushad, Martin Sadle. Early Onset Degenerative Parkinsonism - Consider SPG7 Mutation. Neurology India. vol 69. issue 4. 2021-09-14. PMID:34507444. |
however, the dopamine transporter scan showed abnormal tracer uptake in both basal ganglia, suggestive of degenerative parkinsonism. |
2021-09-14 |
2023-08-13 |
Not clear |
| Peter A Kempster, Laura Perju-Dumbrav. The Thermodynamic Consequences of Parkinson's Disease. Frontiers in neurology. vol 12. 2021-09-14. PMID:34512508. |
that the dopaminergic deficit of pd creates a problem with energy efficiency highlights the role played by the basal ganglia, and by dopamine, in thermodynamic governance. |
2021-09-14 |
2023-08-13 |
Not clear |
| Bryant J Jongkee. Baseline-dependent effect of dopamine's precursor L-tyrosine on working memory gating but not updating. Cognitive, affective & behavioral neuroscience. vol 20. issue 3. 2021-08-30. PMID:32133585. |
this balance is controlled by an input-gating mechanism implemented by dopamine in the basal ganglia. |
2021-08-30 |
2023-08-13 |
human |
| Andrew Schneider, Adam T Sari, Hasan Alhaddad, Youssef Sar. Overview of Therapeutic Drugs and Methods for the Treatment of Parkinson's Disease. CNS & neurological disorders drug targets. vol 19. issue 3. 2021-08-30. PMID:32448109. |
over the past decades, most of the medications for the treatment of pd patients have been used to modulate dopamine concentrations in the basal ganglia. |
2021-08-30 |
2023-08-13 |
Not clear |