| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michinori Koebisu, Takayuki Ishid. [Safinamide Mesilate (Equfina Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 155. issue 4. 2020-11-02. PMID:32612042. |
dopamine deficiency is thought to disrupt motor control of the basal ganglia and cause characteristic motor symptoms in parkinson's disease such as bradykinesia, akinesia, and tremor. |
2020-11-02 |
2023-08-13 |
rat |
| Matthijs C Dorst, Anna Tokarska, Ming Zhou, Kwang Lee, Stefanos Stagkourakis, Christian Broberger, Sotiris Masmanidis, Gilad Silberber. Polysynaptic inhibition between striatal cholinergic interneurons shapes their network activity patterns in a dopamine-dependent manner. Nature communications. vol 11. issue 1. 2020-11-02. PMID:33037215. |
striatal activity is dynamically modulated by acetylcholine and dopamine, both of which are essential for basal ganglia function. |
2020-11-02 |
2023-08-13 |
Not clear |
| Tuğba Cengiz, Saadet Türkboyları, Onur Serdar Gençler, Ömer Anla. The roles of galectin-3 and galectin-4 in the idiopatic Parkinson disease and its progression. Clinical neurology and neurosurgery. vol 184. 2020-10-23. PMID:31147178. |
idiopathic parkinson's disease is a neurodegenerative disease caused by the loss of cells that secrete dopamine in the basal ganglia. |
2020-10-23 |
2023-08-13 |
Not clear |
| Seo Young Kang, Ji Young Yun, Hye Ok Kim, Byung Seok Moon, Hai-Jeon Yoon, Bom Sahn Ki. The Correlation of Salivary Gland Uptake Between 18F-FP-CIT PET/CT and Salivary Scan. Clinical nuclear medicine. vol 45. issue 8. 2020-10-15. PMID:32520511. |
the uptake of dopamine transporter in the bilateral basal ganglia was well preserved, but reduced uptake in the left parotid gland was incidentally detected. |
2020-10-15 |
2023-08-13 |
Not clear |
| Siegfried Muhlack, Patricia Müsch, Sandra Konietzka, Dirk Woitalla, Horst Przuntek, Thomas Mülle. Impact of Oral Fast Release Amantadine on Movement Performance in Patients with Parkinson's Disease. Pharmaceutics. vol 2. issue 3. 2020-10-01. PMID:27721359. |
therefore, performance of complex motion series improved, whereas carrying-out of simple repetitive movements is more associated to the striatal dopamine dependent basal ganglia function. |
2020-10-01 |
2023-08-13 |
Not clear |
| Pamela Valdés, Bernard L Schneide. Gene Therapy: A Promising Approach for Neuroprotection in Parkinson's Disease? Frontiers in neuroanatomy. vol 10. 2020-10-01. PMID:28066194. |
gene therapies that are the most advanced in the clinic have been designed to more effectively compensate for the lack of dopamine signaling in the basal ganglia and rescue the cardinal motor symptoms of pd. |
2020-10-01 |
2023-08-13 |
Not clear |
| Lina M Cómbita, Pascale Voelker, Alicia Abundis-Gutiérrez, Joan P Pozuelos, M Rosario Rued. Influence of the SLC6A3-DAT1 Gene on Multifaceted Measures of Self-regulation in Preschool Children. Frontiers in psychology. vol 8. 2020-10-01. PMID:28154545. |
regulation of dopamine levels within the ean, particularly in the basal ganglia is carried out by the action of dopamine transporters. |
2020-10-01 |
2023-08-13 |
Not clear |
| Dimitri Ryczko, Réjean Dubu. Dopamine and the Brainstem Locomotor Networks: From Lamprey to Human. Frontiers in neuroscience. vol 11. 2020-10-01. PMID:28603482. |
in vertebrates, dopamine neurons are classically known to modulate locomotion via their ascending projections to the basal ganglia that project to brainstem locomotor networks. |
2020-10-01 |
2023-08-13 |
human |
| Dimitri Ryczko, Réjean Dubu. Dopamine and the Brainstem Locomotor Networks: From Lamprey to Human. Frontiers in neuroscience. vol 11. 2020-10-01. PMID:28603482. |
in pathological conditions where dopamine cells are lost, such as in parkinson's disease, locomotor deficits are traditionally associated with the reduced ascending dopaminergic input to the basal ganglia. |
2020-10-01 |
2023-08-13 |
human |
| Sudhakar R Subramaniam, Howard J Federof. Targeting Microglial Activation States as a Therapeutic Avenue in Parkinson's Disease. Frontiers in aging neuroscience. vol 9. 2020-10-01. PMID:28642697. |
the consequent reduction of dopamine in the basal ganglia results in the classical parkinsonian motor phenotype. |
2020-10-01 |
2023-08-13 |
Not clear |
| Yehuda Ben-Shaha. The Impact of Environmental Mn Exposure on Insect Biology. Frontiers in genetics. vol 9. 2020-10-01. PMID:29545824. |
however, chronic environmental exposure to high levels of mn is a well-established risk factor for the etiology of severe, atypical parkinsonian syndrome (manganism) via its accumulation in the basal ganglia, pallidum, and striatum brain regions, which is often associated with abnormal dopamine, gaba, and glutamate neural signaling. |
2020-10-01 |
2023-08-13 |
human |
| Anca-Adriana Arbune, Manuela Arbune, Victorita Stefanesc. Parkinsonian Syndrome and Toxoplasmic Encephalitis. Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures). vol 2. issue 2. 2020-10-01. PMID:29967844. |
associated parkinsonian syndrome in hiv patients is a rare condition, explained by the location of the brain and basal ganglia lesions, and by the observed effect of toxoplasma gondii which increases dopamine metabolism in neural cells. |
2020-10-01 |
2023-08-13 |
human |
| S Creagh, D Warden, M A Latif, A Payda. The New Classes of Synthetic Illicit Drugs Can Significantly Harm the Brain: A Neuro Imaging Perspective with Full Review of MRI Findings. Clinical radiology & imaging journal. vol 2. issue 1. 2020-10-01. PMID:30027157. |
these drugs have detrimental (and often irreversible) effects on the brain and primarily affect the central nervous system by two mechanisms: 1) neural hyper stimulation via increasing activation of certain neurotransmitters (norepinephrine, dopamine, and serotonin), 2) cause significant reduction in cns neural connectivity affecting various brain regions such as the basal ganglia, hippocampus, cerebellum, parietal lobe, and globus pallidus. |
2020-10-01 |
2023-08-13 |
human |
| Yuko Koshimori, Antonio P Strafella, Mikaeel Valli, Vivek Sharma, Sang-Soo Cho, Sylvain Houle, Michael H Thau. Motor Synchronization to Rhythmic Auditory Stimulation (RAS) Attenuates Dopaminergic Responses in Ventral Striatum in Young Healthy Adults: [ Frontiers in neuroscience. vol 13. 2020-10-01. PMID:30837831. |
the current study aimed to investigate ras-induced dopamine (da) responses in basal ganglia (bg) during finger tapping tasks combined with [ |
2020-10-01 |
2023-08-13 |
Not clear |
| Sandeep Kumar, Alok Nath Mohapatra, Hanuman Prasad Sharma, Utkarsha A Singh, Niranjan Ashok Kambi, Thirumurthy Velpandian, Raghav Rajan, Soumya Iyenga. Altering Opioid Neuromodulation in the Songbird Basal Ganglia Modulates Vocalizations. Frontiers in neuroscience. vol 13. 2020-10-01. PMID:31333400. |
although the interplay between endogenous opioids and dopamine (da) in the basal ganglia (bg) is known to underlie diverse motor functions, few studies exist on their role in modulating speech and vocalization. |
2020-10-01 |
2023-08-13 |
Not clear |
| G M Petzinger, D P Holschneider, B E Fisher, S McEwen, N Kintz, M Halliday, W Toy, J W Walsh, J Beeler, M W Jakowe. The Effects of Exercise on Dopamine Neurotransmission in Parkinson's Disease: Targeting Neuroplasticity to Modulate Basal Ganglia Circuitry. Brain plasticity (Amsterdam, Netherlands). vol 1. issue 1. 2020-09-30. PMID:26512345. |
the effects of exercise on dopamine neurotransmission in parkinson's disease: targeting neuroplasticity to modulate basal ganglia circuitry. |
2020-09-30 |
2023-08-13 |
Not clear |
| Katsuhiro Nagatomo, Sechiko Suga, Masato Saitoh, Masahito Kogawa, Kazuto Kobayashi, Yoshio Yamamoto, Katsuya Yamad. Dopamine D1 Receptor Immunoreactivity on Fine Processes of GFAP-Positive Astrocytes in the Substantia Nigra Pars Reticulata of Adult Mouse. Frontiers in neuroanatomy. vol 11. 2020-09-30. PMID:28203148. |
substantia nigra pars reticulata (snr), the major output nucleus of the basal ganglia, receives dopamine from dendrites extending from dopaminergic neurons of the adjacent nucleus pars compacta (snc), which is known for its selective degeneration in parkinson's disease. |
2020-09-30 |
2023-08-13 |
mouse |
| Osamu Shouno, Yoshihisa Tachibana, Atsushi Nambu, Kenji Doy. Computational Model of Recurrent Subthalamo-Pallidal Circuit for Generation of Parkinsonian Oscillations. Frontiers in neuroanatomy. vol 11. 2020-09-30. PMID:28377699. |
parkinson's disease is a movement disorder caused by dopamine depletion in the basal ganglia. |
2020-09-30 |
2023-08-13 |
human |
| Lan-Xiang Liu, Dan Du, Tao Zheng, Yuan Fang, Yan-Sheng Chen, Hui-Ling Yi, Qing-Yuan He, Da-Wei Gao, Qing-Lei Sh. Detecting dopaminergic neuronal degeneration using diffusion tensor imaging in a rotenone-induced rat model of Parkinson's disease: fractional anisotropy and mean diffusivity values. Neural regeneration research. vol 12. issue 9. 2020-09-30. PMID:29089995. |
dopamine content in the basal ganglia is strongly associated with the degree of dopaminergic neuron loss in the substantia nigra pars compacta. |
2020-09-30 |
2023-08-13 |
rat |
| Lan-Xiang Liu, Dan Du, Tao Zheng, Yuan Fang, Yan-Sheng Chen, Hui-Ling Yi, Qing-Yuan He, Da-Wei Gao, Qing-Lei Sh. Detecting dopaminergic neuronal degeneration using diffusion tensor imaging in a rotenone-induced rat model of Parkinson's disease: fractional anisotropy and mean diffusivity values. Neural regeneration research. vol 12. issue 9. 2020-09-30. PMID:29089995. |
symptoms of parkinson's disease might not arise until more than 50% of the substantia nigra pars compacta is lost and the dopamine content in the basal ganglia is reduced by more than 80%. |
2020-09-30 |
2023-08-13 |
rat |