| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dmitrii I Todorov, Robert A Capps, William H Barnett, Elizaveta M Latash, Taegyo Kim, Khaldoun C Hamade, Sergey N Markin, Ilya A Rybak, Yaroslav I Molko. The interplay between cerebellum and basal ganglia in motor adaptation: A modeling study. PloS one. vol 14. issue 4. 2019-12-20. PMID:30978216. |
to do so, this circuit modulates learning rate in the cerebellum and dopamine release in basal ganglia depending on error-based learning efficiency. |
2019-12-20 |
2023-08-13 |
Not clear |
| M. Amalric, C. Baunez, A. Nieoullo. Does the blockade of excitatory amino acid transmission in the basal ganglia simply reverse reaction time deficits induced by dopamine inactivation? Behavioural pharmacology. vol 6. issue 5 And 6. 2019-11-20. PMID:11224358. |
does the blockade of excitatory amino acid transmission in the basal ganglia simply reverse reaction time deficits induced by dopamine inactivation? |
2019-11-20 |
2023-08-12 |
rat |
| M. Amalric, C. Baunez, A. Nieoullo. Does the blockade of excitatory amino acid transmission in the basal ganglia simply reverse reaction time deficits induced by dopamine inactivation? Behavioural pharmacology. vol 6. issue 5 And 6. 2019-11-20. PMID:11224358. |
it has recently been hypothesized that excessive excitatory amino acid (eaa) activity in the corticostriatal pathway and in the subthalamic nucleus could account for the expression of the motor deficits resulting from alteration in dopamine function in the basal ganglia. |
2019-11-20 |
2023-08-12 |
rat |
| Ph. Damie. [On-off fluctuations] Revue neurologique. vol 158. issue 122. 2019-11-20. PMID:12690318. |
a reduction in dopamine storage capacity) are clearly involved, there are also complex postsynaptic anomalies, affecting all the basal ganglia circuitry. |
2019-11-20 |
2023-08-12 |
Not clear |
| Arun Sing. Oscillatory activity in the cortico-basal ganglia-thalamic neural circuits in Parkinson's disease. The European journal of neuroscience. vol 48. issue 8. 2019-11-14. PMID:29381817. |
dopamine is an important neurotransmitter that maintains the balance within the basal ganglia between the direct pathway, which promotes movement, and the indirect pathway, which inhibits movement. |
2019-11-14 |
2023-08-13 |
Not clear |
| Véronique Sgambato, Léon Trembla. Pathophysiology of dyskinesia and behavioral disorders in non-human primates: the role of serotonergic fibers. Journal of neural transmission (Vienna, Austria : 1996). vol 125. issue 8. 2019-11-04. PMID:29502255. |
the same pathological mechanism, i.e., an imbalance between serotonin and dopamine terminals may, therefore, favor l-dopa-induced adverse effects according to the basal ganglia territory it inhabits. |
2019-11-04 |
2023-08-13 |
monkey |
| Nedjeljka Ivica, Ulrike Richter, Joel Sjöbom, Ivani Brys, Martin Tamtè, Per Petersso. Changes in neuronal activity of cortico-basal ganglia-thalamic networks induced by acute dopaminergic manipulations in rats. The European journal of neuroscience. vol 47. issue 3. 2019-10-22. PMID:29250896. |
the basal ganglia are thought to be particularly sensitive to changes in dopaminergic tone, and the realization that reduced dopaminergic signaling causes pronounced motor dysfunction is the rationale behind dopamine replacement therapy in parkinson's disease. |
2019-10-22 |
2023-08-13 |
rat |
| Jin-Zhong Huang, Yi Ren, Yuan Xu, Tao Chen, Terry C Xia, Zhuo-Ri Li, Jian-Nong Zhao, Fei Hua, Shi-Ying Sheng, Ying Xi. The delta-opioid receptor and Parkinson's disease. CNS neuroscience & therapeutics. vol 24. issue 12. 2019-10-14. PMID:30076686. |
although it is known that the major characteristics of pd pathophysiology are the dysfunction of basal ganglia due to injury/loss of dopaminergic neurons in the substantia nigra pars compacta dopaminergic and exhaustion of corpus striatum dopamine, therapeutic modalities for pd are limited in clinical settings up to date. |
2019-10-14 |
2023-08-13 |
Not clear |
| Mark D Humphries, Jose Angel Obeso, Jakob Kisbye Dreye. Insights into Parkinson's disease from computational models of the basal ganglia. Journal of neurology, neurosurgery, and psychiatry. vol 89. issue 11. 2019-10-03. PMID:29666208. |
for mechanisms, we review models that capture the effects of losing dopamine on basal ganglia function; for dynamics, we discuss models that have transformed our understanding of how beta-band (15-30 hz) oscillations arise in the parkinsonian basal ganglia. |
2019-10-03 |
2023-08-13 |
Not clear |
| Thomas Wichmann, Hagai Bergman, Mahlon R DeLon. Basal ganglia, movement disorders and deep brain stimulation: advances made through non-human primate research. Journal of neural transmission (Vienna, Austria : 1996). vol 125. issue 3. 2019-09-27. PMID:28601961. |
striatal dopamine release alters the activity of striatal projection neurons which, in turn, influences the (inhibitory) basal ganglia output. |
2019-09-27 |
2023-08-13 |
Not clear |
| Thomas Wichmann, Hagai Bergman, Mahlon R DeLon. Basal ganglia, movement disorders and deep brain stimulation: advances made through non-human primate research. Journal of neural transmission (Vienna, Austria : 1996). vol 125. issue 3. 2019-09-27. PMID:28601961. |
in parkinsonism, the loss of striatal dopamine results in the emergence of oscillatory burst patterns of firing of basal ganglia output neurons, increased synchrony of the discharge of neighboring basal ganglia neurons, and an overall increase in basal ganglia output. |
2019-09-27 |
2023-08-13 |
Not clear |
| Tiago V Maia, Vasco A Conceiçã. Dopaminergic Disturbances in Tourette Syndrome: An Integrative Account. Biological psychiatry. vol 84. issue 5. 2019-09-27. PMID:29656800. |
we have previously shown, using a computational model of the role of dopamine in basal ganglia, that increased tonic dopamine and increased phasic dopamine likely increase the propensities to express and learn tics, respectively. |
2019-09-27 |
2023-08-13 |
Not clear |
| Elijah A Petter, Samuel J Gershman, Warren H Mec. Integrating Models of Interval Timing and Reinforcement Learning. Trends in cognitive sciences. vol 22. issue 10. 2019-09-23. PMID:30266150. |
we describe how these systems are subserved by a computational division of labor between several brain regions, with a focus on the basal ganglia and the hippocampus, as well as how these regions are influenced by the neuromodulator dopamine. |
2019-09-23 |
2023-08-13 |
Not clear |
| Giada Spigolon, Anna Cavaccini, Massimo Trusel, Raffaella Tonini, Gilberto Fison. cJun N-terminal kinase (JNK) mediates cortico-striatal signaling in a model of Parkinson's disease. Neurobiology of disease. vol 110. 2019-09-06. PMID:29107639. |
this effect is secondary to dopamine depletion, and is restricted to the striatal projection neurons that innervate directly the output structures of the basal ganglia (dspn). |
2019-09-06 |
2023-08-13 |
mouse |
| Jan Aaseth, Petr Dusek, Per M Roo. Prevention of progression in Parkinson's disease. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine. vol 31. issue 5. 2019-08-19. PMID:30030679. |
such exposure together with mitochondrial dysfunction evokes a destructive cascade of biochemical events, including oxidative stress and degeneration of the sensitive dopamine (da) production system in the basal ganglia. |
2019-08-19 |
2023-08-13 |
Not clear |
| Daniela Mercatelli, Clarissa Anna Pisanò, Salvatore Novello, Michele Morar. NOP Receptor Ligands and Parkinson's Disease. Handbook of experimental pharmacology. vol 254. 2019-07-26. PMID:30689087. |
we will first discuss data showing that the central n/ofq-nop receptor system undergoes plastic changes in different basal ganglia nuclei following dopamine depletion. |
2019-07-26 |
2023-08-13 |
human |
| Mark S Moehle, Tristano Pancani, Nellie Byun, Samantha E Yohn, George H Wilson, Johnathan W Dickerson, Daniel H Remke, Zixiu Xiang, Colleen M Niswender, Jürgen Wess, Carrie K Jones, Craig W Lindsley, Jerri M Rook, P Jeffrey Con. Cholinergic Projections to the Substantia Nigra Pars Reticulata Inhibit Dopamine Modulation of Basal Ganglia through the M Neuron. vol 96. issue 6. 2019-07-05. PMID:29268098. |
cholinergic projections to the substantia nigra pars reticulata inhibit dopamine modulation of basal ganglia through the m cholinergic regulation of dopaminergic inputs into the striatum is critical for normal basal ganglia (bg) function. |
2019-07-05 |
2023-08-13 |
Not clear |
| Thomas R Barber, Ludovica Griffanti, Kinan Muhammed, Daniel S Drew, Kevin M Bradley, Daniel R McGowan, Marie Crabbe, Christine Lo, Clare E Mackay, Masud Husain, Michele T Hu, Johannes C Klei. Apathy in rapid eye movement sleep behaviour disorder is associated with serotonin depletion in the dorsal raphe nucleus. Brain : a journal of neurology. vol 141. issue 10. 2019-07-05. PMID:30212839. |
the integrity of the raphe serotonergic system can be assessed alongside dopaminergic basal ganglia imaging using the radioligand 123i-ioflupane, which binds both serotonin and dopamine transporters. |
2019-07-05 |
2023-08-13 |
Not clear |
| Konstantin Kaganovsky, Jun B Din. The Locomotion Tug-of-War: Cholinergic and Dopaminergic Interactions Outside the Striatum. Neuron. vol 96. issue 6. 2019-07-02. PMID:29268090. |
(2017) demonstrate that presynaptic muscarinic receptors counteract the effects of dopamine in an output nucleus of the basal ganglia. |
2019-07-02 |
2023-08-13 |
Not clear |
| Alessandra Perugini, Michele A Bass. Perceptual decisions based on previously learned information are independent of dopaminergic tone. Journal of neurophysiology. vol 119. issue 3. 2019-06-10. PMID:29167328. |
to rule out effects of long-term da treatment and dopaminergic neuronal loss such as occur in pd, we also tested a group of people with dopa-unresponsive focal dystonia, a disease that involves the basal ganglia, like pd, but has motor symptoms that are insensitive to dopamine treatment and is not thought to involve frontal cortical da circuits, unlike pd. |
2019-06-10 |
2023-08-13 |
Not clear |