| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Regina Rumpel, Mesbah Alam, Lisa M Schwarz, Andreas Ratzka, Xingxing Jin, Joachim K Krauss, Claudia Grothe, Kerstin Schwab. Neuronal firing activity in the basal ganglia after striatal transplantation of dopamine neurons in hemiparkinsonian rats. Neuroscience. vol 360. 2018-06-05. PMID:28790019. |
the loss of nigral dopaminergic neurons and the resulting dopamine (da) depletion in the striatum (str) lead to altered neuronal activity and enhanced beta activity in various regions of the basal ganglia (bg) motor loop in patients with parkinson's disease and in rodents in the 6-hydroxydopamine (6-ohda)-lesioned rat model. |
2018-06-05 |
2023-08-13 |
human |
| Witold J Lipski, Sofia M Dibble, Linda Rinaman, Anthony A Grac. Psychogenic Stress Activates C-Fos in Nucleus Accumbens-Projecting Neurons of the Hippocampal Ventral Subiculum. The international journal of neuropsychopharmacology. vol 20. issue 10. 2018-06-05. PMID:28977522. |
artificial activation of the ventral subiculum can excite medium spiny neurons of the nucleus accumbens and can increase the excitability of mesolimbic dopamine neurons via a polysynaptic pathway through the basal ganglia. |
2018-06-05 |
2023-08-13 |
Not clear |
| Maribel Pérez-Rodríguez, Esperanza García-Mendoza, Eunice D Farfán-García, Bhaskar C Das, Fabiola J Ciprés-Flores, José G Trujillo-Ferrara, Feliciano Tamay-Cach, Marvin A Soriano-Ursú. Not all boronic acids with a five-membered cycle induce tremor, neuronal damage and decreased dopamine. Neurotoxicology. vol 62. 2018-05-30. PMID:28595910. |
the various manifestations generated by these compounds can be linked, in part, to different levels of dopamine (measured by hplc) and degrees of neuronal damage in the basal ganglia and cerebellum. |
2018-05-30 |
2023-08-13 |
mouse |
| Agata Budzillo, Alison Duffy, Kimberly E Miller, Adrienne L Fairhall, David J Perke. Dopaminergic modulation of basal ganglia output through coupled excitation-inhibition. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 22. 2018-05-15. PMID:28507134. |
dopamine in the basal ganglia reduces trial-to-trial neural variability when the bird engages in courtship song. |
2018-05-15 |
2023-08-13 |
Not clear |
| Ivan Carrera, Lucia Fernandez-Novoa, Carolina Sampedro, Ramon Cacabelo. Neuroprotective Effect of Atremorine in an Experimental Model of Parkinson's Disease. Current pharmaceutical design. vol 23. issue 18. 2018-05-09. PMID:28190394. |
data demonstrated that atremorine promotes neuroprotection and behavior recovery in the injured mtpt-mouse brain by modulating the expression levels of tyrosine hydroxylase, glial proteins, apoptosis and endogenous dopamine and neuromelanin concentrations, probably the key to recover the basal ganglia function. |
2018-05-09 |
2023-08-13 |
mouse |
| Jaishree Jalewa, Mohit Kumar Sharma, Simon Gengler, Christian Hölsche. A novel GLP-1/GIP dual receptor agonist protects from 6-OHDA lesion in a rat model of Parkinson's disease. Neuropharmacology. vol 117. 2018-05-03. PMID:28223210. |
dopamine levels in the basal ganglia were reduced by 6-ohda lesion and increased by da-jc1. |
2018-05-03 |
2023-08-13 |
mouse |
| Amy R Dunn, Kristen A Stout, Minagi Ozawa, Kelly M Lohr, Carlie A Hoffman, Alison I Bernstein, Yingjie Li, Minzheng Wang, Carmelo Sgobio, Namratha Sastry, Huaibin Cai, W Michael Caudle, Gary W Mille. Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 11. 2018-04-23. PMID:28246328. |
here we identify sv2c as a mediator of dopamine homeostasis and report that disrupted expression of sv2c within the basal ganglia is a pathological feature of pd. |
2018-04-23 |
2023-08-13 |
mouse |
| Sebastian Markett, Marcel A de Reus, Martin Reuter, Christian Montag, Bernd Weber, Jan-Christoph Schoene-Bake, Martijn P van den Heuve. Variation on the dopamine D2 receptor gene (DRD2) is associated with basal ganglia-to-frontal structural connectivity. NeuroImage. vol 155. 2018-04-20. PMID:28392487. |
carriers of the cc genotype who are characterized by elevated striatal dopamine turnaround showed higher integrity in terms of fractional anisotropy on fiber tracts between the basal ganglia and frontal regions compared to carriers of the ct and tt variant. |
2018-04-20 |
2023-08-13 |
human |
| Janet Charoensook, Gerald A Maguir. A case series on the effectiveness of lurasidone in patients with stuttering. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. vol 29. issue 3. 2018-04-17. PMID:28738099. |
the dopamine hypothesis of stuttering explains that abnormally increased cerebral dopamine affects the balanced levels that maintain the basal ganglia circuits, which helps with timing cues in initiating speech. |
2018-04-17 |
2023-08-13 |
Not clear |
| Harith Akram, Chengyuan Wu, Jonathan Hyam, Thomas Foltynie, Patricia Limousin, Enrico De Vita, Tarek Yousry, Marjan Jahanshahi, Marwan Hariz, Timothy Behrens, John Ashburner, Ludvic Zrinz. l-Dopa responsiveness is associated with distinctive connectivity patterns in advanced Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 32. issue 6. 2018-03-30. PMID:28597560. |
neuronal loss and dopamine depletion alter motor signal processing between cortical motor areas, basal ganglia, and the thalamus, resulting in the motor manifestations of parkinson's disease. |
2018-03-30 |
2023-08-13 |
Not clear |
| Patrik Fazio, Martin Schain, Ladislav Mrzljak, Nahid Amini, Sangram Nag, Nabil Al-Tawil, Cheryl J Fitzer-Attas, Juliana Bronzova, Bernhard Landwehrmeyer, Cristina Sampaio, Christer Halldin, Andrea Varron. Patterns of age related changes for phosphodiesterase type-10A in comparison with dopamine D NeuroImage. vol 152. 2018-03-09. PMID:28254508. |
pde10a is expressed on striatal neurones in basal ganglia where other known molecular targets are enriched such as dopamine d |
2018-03-09 |
2023-08-13 |
Not clear |
| R Abboud, C Noronha, V A Diwadka. Motor system dysfunction in the schizophrenia diathesis: Neural systems to neurotransmitters. European psychiatry : the journal of the Association of European Psychiatrists. vol 44. 2018-03-07. PMID:28641214. |
at the molecular scale, both dopamine and γ-aminobutyric acid (gaba) abnormalities have been associated with working memory dysfunction, but particularly relating to the basal ganglia and the prefrontal cortex respectively. |
2018-03-07 |
2023-08-13 |
human |
| M J Sanchez-Catalan, J Kaufling, F Georges, P Veinante, M Barro. The antero-posterior heterogeneity of the ventral tegmental area. Neuroscience. vol 282. 2018-01-26. PMID:25241061. |
it controls vta and substantia nigra dopamine cells, thus exerting a major influence on basal ganglia functions. |
2018-01-26 |
2023-08-13 |
Not clear |
| Arun Singh, Klaus Mewes, Robert E Gross, Mahlon R DeLong, José A Obeso, Stella M Pap. Human striatal recordings reveal abnormal discharge of projection neurons in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 34. 2018-01-26. PMID:27503874. |
circuitry models of parkinson's disease (pd) are based on striatal dopamine loss and aberrant striatal inputs into the basal ganglia network. |
2018-01-26 |
2023-08-13 |
human |
| Katsuya Yamada, Susumu Takahashi, Fuyuki Karube, Fumino Fujiyama, Kazuto Kobayashi, Akinori Nishi, Toshihiko Momiyam. Neuronal circuits and physiological roles of the basal ganglia in terms of transmitters, receptors and related disorders. The journal of physiological sciences : JPS. vol 66. issue 6. 2018-01-25. PMID:26979514. |
based on their expertise in their respective fields, as denoted in the text, the authors discuss five distinct research topics, as follows: (1) area-specific dopamine receptor expression of astrocytes in basal ganglia, (2) the role of physiologically released dopamine in the striatum, (3) control of behavioral flexibility by striatal cholinergic interneurons, (4) regulation of phosphorylation states of darpp-32 by protein phosphatases and (5) physiological perspective on deep brain stimulation with optogenetics and closed-loop control for ameliorating parkinsonism. |
2018-01-25 |
2023-08-13 |
Not clear |
| Wolfram Schult. Reward functions of the basal ganglia. Journal of neural transmission (Vienna, Austria : 1996). vol 123. issue 7. 2018-01-23. PMID:26838982. |
this review describes the reward functions of three brain structures that are major components of the basal ganglia or are closely associated with the basal ganglia, namely midbrain dopamine neurons, pedunculopontine nucleus, and striatum (caudate nucleus, putamen, nucleus accumbens). |
2018-01-23 |
2023-08-13 |
Not clear |
| Marta Celorrio, Diana Fernández-Suárez, Estefanía Rojo-Bustamante, Víctor Echeverry-Alzate, María J Ramírez, Cecilia J Hillard, José A López-Moreno, Rafael Maldonado, Julen Oyarzábal, Rafael Franco, María S Aymeric. Fatty acid amide hydrolase inhibition for the symptomatic relief of Parkinson's disease. Brain, behavior, and immunity. vol 57. 2018-01-11. PMID:27318096. |
elements of the endocannabinoid system are strongly expressed in the basal ganglia where they suffer profound rearrangements after dopamine depletion. |
2018-01-11 |
2023-08-13 |
mouse |
| Jacob J Crouse, Joseph R Phillips, Marjan Jahanshahi, Ahmed A Moustaf. Postural instability and falls in Parkinson's disease. Reviews in the neurosciences. vol 27. issue 5. 2018-01-02. PMID:26966928. |
the delayed effect of dopaminergic medication combined with the success of extrastriatal deep brain stimulation suggests that pi involves neurotransmitter systems other than dopamine and brain regions extending beyond the basal ganglia, further challenging the traditional view of pd as a predominantly single-system neurodegenerative disease. |
2018-01-02 |
2023-08-13 |
Not clear |
| W Michael Caudl. Occupational Metal Exposure and Parkinsonism. Advances in neurobiology. vol 18. 2017-12-28. PMID:28889266. |
of these, metals have received significant attention given their propensity to accumulate in the basal ganglia and participate in neurotoxic cascades, through the generation of reactive oxygen species as well as their pathogenic interaction with intracellular targets in the dopamine neuron. |
2017-12-28 |
2023-08-13 |
Not clear |
| Sten Grillner, Brita Robertso. The Basal Ganglia Over 500 Million Years. Current biology : CB. vol 26. issue 20. 2017-12-26. PMID:27780050. |
the 'indirect pathway' with dopamine d2 receptor-expressing spns and intrinsic basal ganglia nuclei is also conserved. |
2017-12-26 |
2023-08-13 |
Not clear |