| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fernando Caravaggio, Shinichiro Nakajima, Eric Plitman, Philip Gerretsen, Jun Ku Chung, Yusuke Iwata, Ariel Graff-Guerrer. The effect of striatal dopamine depletion on striatal and cortical glutamate: A mini-review. Progress in neuro-psychopharmacology & biological psychiatry. vol 65. 2016-09-14. PMID:26334687. |
however, it is unclear a priori how alterations in striatal dopamine should modulate glutamate concentrations in the basal ganglia. |
2016-09-14 |
2023-08-13 |
human |
| Fernando Caravaggio, Shinichiro Nakajima, Eric Plitman, Philip Gerretsen, Jun Ku Chung, Yusuke Iwata, Ariel Graff-Guerrer. The effect of striatal dopamine depletion on striatal and cortical glutamate: A mini-review. Progress in neuro-psychopharmacology & biological psychiatry. vol 65. 2016-09-14. PMID:26334687. |
the review concludes that chronic dopamine depletion (>4months) produces decreases in striatal glutamate levels which are consistent with the classical model of the basal ganglia. |
2016-09-14 |
2023-08-13 |
human |
| Elena Brazhnik, Alex J McCoy, Nikolay Novikov, Christina E Hatch, Judith R Walter. Ventral Medial Thalamic Nucleus Promotes Synchronization of Increased High Beta Oscillatory Activity in the Basal Ganglia-Thalamocortical Network of the Hemiparkinsonian Rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 15. 2016-09-08. PMID:27076419. |
loss of dopamine is associated with increased synchronization and oscillatory activity in the subthalamic nucleus and basal ganglia (bg) output nuclei in both parkinson's disease (pd) patients and animal models of pd. |
2016-09-08 |
2023-08-13 |
rat |
| Kine S N Dervola, Espen B Johansen, S Ivar Walaas, Frode Fonnu. Gender-dependent and genotype-sensitive monoaminergic changes induced by polychlorinated biphenyl 153 in the rat brain. Neurotoxicology. vol 50. 2016-08-24. PMID:26215117. |
pcb 153 may therefore induce neostriatal toxicity through both presynaptic and postsynaptic mechanisms in both genotypes and genders, including effects on the aspiny interneurons, which employ the d5 receptor to mediate dopamine effects on interneurons in the basal ganglia. |
2016-08-24 |
2023-08-13 |
rat |
| Satomi Chiken, Asako Sato, Chikara Ohta, Makoto Kurokawa, Satoshi Arai, Jun Maeshima, Tomoko Sunayama-Morita, Toshikuni Sasaoka, Atsushi Namb. Dopamine D1 Receptor-Mediated Transmission Maintains Information Flow Through the Cortico-Striato-Entopeduncular Direct Pathway to Release Movements. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 12. 2016-08-18. PMID:26443442. |
in the basal ganglia (bg), dopamine plays a pivotal role in motor control, and dopamine deficiency results in severe motor dysfunctions as seen in parkinson's disease. |
2016-08-18 |
2023-08-13 |
mouse |
| WeiZhen Liu, Yanwei Li, Jaishree Jalewa, Taylor Saunders-Wood, Lin Li, Christian Hölsche. Neuroprotective effects of an oxyntomodulin analogue in the MPTP mouse model of Parkinson's disease. European journal of pharmacology. vol 765. 2016-08-12. PMID:26302060. |
oxy treatment prevented or reversed the mptp- induced motor impairment (rotarod, spontaneous locomotion, swim activity, muscle strength test), the mptp-induced reduction in tyrosine hydroxylase (th) levels (dopamine synthesis) in the substantia nigra and basal ganglia, the reduction of the synaptic marker synapstophysin, the inactivation of the growth factor kinase akt/pkb and of the anti-apoptotic signaling molecule bcl-2, and the increase of levels of the pro-inflammatory cytokine tnf-α. |
2016-08-12 |
2023-08-13 |
mouse |
| Satoshi Orim. [Dementia with Lewy bodies]. Nihon rinsho. Japanese journal of clinical medicine. vol 74. issue 3. 2016-07-25. PMID:27025091. |
in regard to imaging tools, dlb patients have milder atrophy of medial temporal lobe by brain mri, reduced occipital activity by spect or pet, reduced mibg uptake by mibg cardiac scintigraphy, and low dopamine transporter activity in the basal ganglia by spect or pet. |
2016-07-25 |
2023-08-13 |
Not clear |
| Mona Buhusi, Kaitlin Olsen, Benjamin Z Yang, Catalin V Buhus. Stress-Induced Executive Dysfunction in GDNF-Deficient Mice, A Mouse Model of Parkinsonism. Frontiers in behavioral neuroscience. vol 10. 2016-07-22. PMID:27445722. |
glial-derived neurotrophic factor (gdnf) is essential for regulating dopamine (da) release in the basal ganglia and for the survival of dopaminergic neurons; gdnf-deficient mice are considered an animal model for aging-related parkinsonism. |
2016-07-22 |
2023-08-13 |
mouse |
| Kendra D Bunner, George V Rebe. Corticostriatal Dysfunction in Huntington's Disease: The Basics. Frontiers in human neuroscience. vol 10. 2016-07-22. PMID:27445757. |
parallel but less-well characterized changes in dopamine (da), a key modulator of glu activation, ensure further deficits in neuronal communication throughout the basal ganglia. |
2016-07-22 |
2023-08-13 |
Not clear |
| Rafieh Alizadeh, Gholamreza Hassanzadeh, Mansoureh Soleimani, Mohammad Taghi Joghataei, Vahid Siavashi, Zhinoos Khorgami, Mahmoudreza Hadjighasse. Gender and age related changes in number of dopaminergic neurons in adult human olfactory bulb. Journal of chemical neuroanatomy. vol 69. 2016-07-20. PMID:26212581. |
dopamine is one of the major brain neurotransmitters, and the loss of dopaminergic neurons in basal ganglia cause motor deficits in parkinson's disease. |
2016-07-20 |
2023-08-13 |
human |
| Davide Ferrazzoli, Adrian Carter, Fatma S Ustun, Grazia Palamara, Paola Ortelli, Roberto Maestri, Murat Yücel, Giuseppe Frazzitt. Dopamine Replacement Therapy, Learning and Reward Prediction in Parkinson's Disease: Implications for Rehabilitation. Frontiers in behavioral neuroscience. vol 10. 2016-07-06. PMID:27378872. |
the principal feature of parkinson's disease (pd) is the impaired ability to acquire and express habitual-automatic actions due to the loss of dopamine in the dorsolateral striatum, the region of the basal ganglia associated with the control of habitual behavior. |
2016-07-06 |
2023-08-13 |
Not clear |
| Chiara Baston, Manuela Contin, Giovanna Calandra Buonaura, Pietro Cortelli, Mauro Ursin. A Mathematical Model of Levodopa Medication Effect on Basal Ganglia in Parkinson's Disease: An Application to the Alternate Finger Tapping Task. Frontiers in human neuroscience. vol 10. 2016-07-06. PMID:27378881. |
the model can be of value to gain a deeper understanding on the pharmacokinetics and pharmacodynamics of the medication, and on the way dopamine is exploited in the neural circuitry of the basal ganglia in patients at different stages of the disease progression. |
2016-07-06 |
2023-08-13 |
Not clear |
| Dardo Tomasi, Gene-Jack Wang, Yana Studentsova, Nora D Volko. Dissecting Neural Responses to Temporal Prediction, Attention, and Memory: Effects of Reward Learning and Interoception on Time Perception. Cerebral cortex (New York, N.Y. : 1991). vol 25. issue 10. 2016-07-01. PMID:25389123. |
our sense of time is modulated by emotional and interoceptive (corporal) states that are hypothesized to rely on a dopamine (da)-modulated "internal clock" in the basal ganglia. |
2016-07-01 |
2023-08-13 |
human |
| Eylem Oğuz, İbrahim Öztürk, Derya Özkan, Jülide Ergil, Gözde Bumin Aydı. Parkinson's Disease and Spinal Anaesthesia. Turkish journal of anaesthesiology and reanimation. vol 42. issue 5. 2016-07-01. PMID:27366437. |
parkinson's is a neurodegenerative disease characterized by increased activity of gaba in basal ganglia and the loss of dopamine in nigrostriatum, associated with rigidity, resting tremor, gait with accelerating steps, and fixed inexpressive face. |
2016-07-01 |
2023-08-13 |
Not clear |
| Philip R L Parker, Arnaud L Lalive, Anatol C Kreitze. Pathway-Specific Remodeling of Thalamostriatal Synapses in Parkinsonian Mice. Neuron. vol 89. issue 4. 2016-06-28. PMID:26833136. |
we found that dopamine depletion selectively decreased synaptic strength at thalamic inputs to dmsns, suggesting that thalamus drives asymmetric activation of basal ganglia circuitry underlying parkinsonian motor impairments. |
2016-06-28 |
2023-08-13 |
mouse |
| Viviane E Bernedo Paredes, Hans-Georg Buchholz, Martin Gartenschläger, Markus Breimhorst, Mathias Schreckenberger, Konrad J Werhah. Reduced D2/D3 Receptor Binding of Extrastriatal and Striatal Regions in Temporal Lobe Epilepsy. PloS one. vol 10. issue 11. 2016-06-14. PMID:26544593. |
dopamine is an endogenous neuromodulator in cortical circuits and the basal ganglia. |
2016-06-14 |
2023-08-13 |
Not clear |
| Jia Liu, Chun-li Duan, Hui Yan. [Research Progress of Pathogenesis and Treatment of Parkinsons Disease]. Sheng li ke xue jin zhan [Progress in physiology]. vol 46. issue 3. 2016-06-10. PMID:26521479. |
the most prominent symptom of pd is the impairment of motor behavior due to the loss of dopaminergic neurons and the consequent loss of the dopamine signaling in the basal ganglia. |
2016-06-10 |
2023-08-13 |
Not clear |
| Lixin Zhang, Chuncui Zhang, Feng He, Xin Zhao, Hongzhi Qi, Baikun Wan, Dong Min. [Research Progress on the Interaction Effects and Its Neural Mechanisms between Physical Fatigue and Mental Fatigue]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. vol 32. issue 5. 2016-06-10. PMID:26964325. |
revealing the basal ganglia function and dopamine release may be important to explore the neural mechanisms between physical fatigue and mental fatigue. |
2016-06-10 |
2023-08-13 |
Not clear |
| Arpiar Saunders, Ian A Oldenburg, Vladimir K Berezovskii, Caroline A Johnson, Nathan D Kingery, Hunter L Elliott, Tiao Xie, Charles R Gerfen, Bernardo L Sabatin. A direct GABAergic output from the basal ganglia to frontal cortex. Nature. vol 521. issue 7550. 2016-06-02. PMID:25739505. |
furthermore, ispn inhibition of gp-fc cells is sensitive to dopamine 2 receptor signalling, revealing a pathway by which drugs that target dopamine receptors for the treatment of neuropsychiatric disorders can act in the basal ganglia to modulate frontal cortices. |
2016-06-02 |
2023-08-13 |
Not clear |
| Tomás R Guilarte, Kalynda K Gonzale. Manganese-Induced Parkinsonism Is Not Idiopathic Parkinson's Disease: Environmental and Genetic Evidence. Toxicological sciences : an official journal of the Society of Toxicology. vol 146. issue 2. 2016-05-31. PMID:26220508. |
over the last decade, supporting evidence from human and nonhuman primates has emerged that mn-induced parkinsonism partially results from damage to basal ganglia nuclei of the striatal "direct pathway" (ie, the caudate/putamen, internal globus pallidus, and substantia nigra pars reticulata) and a marked inhibition of striatal dopamine release in the absence of nigrostriatal dopamine terminal degeneration. |
2016-05-31 |
2023-08-13 |
human |