| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Silvia R Delgado, Leticia Tornes, Janice Maldonado, Jeffrey Hernandez, Yesica Campos, Kottil Rammoha. Neuroleptic Malignant Syndrome Associated with Refractory Acute Disseminated Encephalomyelitis. Case reports in neurology. vol 8. issue 1. 2016-05-30. PMID:27239186. |
in our patient, acute demyelination with severe bilateral inflammation of the basal ganglia could have caused a state of central dopamine depletion, creating proper conditions for the development of nms. |
2016-05-30 |
2023-08-13 |
Not clear |
| Marc Deffains, Hagai Bergma. Striatal cholinergic interneurons and cortico-striatal synaptic plasticity in health and disease. Movement disorders : official journal of the Movement Disorder Society. vol 30. issue 8. 2016-05-06. PMID:26095280. |
basal ganglia disorders such as parkinson's disease, dystonia, and huntington's disease are characterized by a dysregulation of the basal ganglia neuromodulators (dopamine, acetylcholine, and others), which impacts cortico-striatal transmission. |
2016-05-06 |
2023-08-13 |
Not clear |
| Kenji Morita, Yasuo Kawaguch. Computing reward-prediction error: an integrated account of cortical timing and basal-ganglia pathways for appetitive and aversive learning. The European journal of neuroscience. vol 42. issue 4. 2016-05-06. PMID:26095906. |
there are two prevailing notions regarding the involvement of the corticobasal ganglia system in value-based learning: (i) the direct and indirect pathways of the basal ganglia are crucial for appetitive and aversive learning, respectively, and (ii) the activity of midbrain dopamine neurons represents reward-prediction error. |
2016-05-06 |
2023-08-13 |
human |
| W Liu, J Jalewa, M Sharma, G Li, L Li, C Hölsche. Neuroprotective effects of lixisenatide and liraglutide in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. Neuroscience. vol 303. 2016-05-06. PMID:26141845. |
both liraglutide and lixisenatide showed effects in preventing the mptp-induced motor impairment (rotarod, open-field locomotion, catalepsy test), reduction in tyrosine hydroxylase (th) levels (dopamine synthesis) in the substantia nigra and basal ganglia, a reduction of the pro-apoptotic signaling molecule bax and an increase in the anti-apoptotic signaling molecule b-cell lymphoma-2. |
2016-05-06 |
2023-08-13 |
mouse |
| Satoshi Ikemoto, Chen Yang, Aaron Ta. Basal ganglia circuit loops, dopamine and motivation: A review and enquiry. Behavioural brain research. vol 290. 2016-04-04. PMID:25907747. |
basal ganglia circuit loops, dopamine and motivation: a review and enquiry. |
2016-04-04 |
2023-08-13 |
Not clear |
| Maxime Cazorla, Un Jung Kang, Christoph Kellendon. Balancing the basal ganglia circuitry: a possible new role for dopamine D2 receptors in health and disease. Movement disorders : official journal of the Movement Disorder Society. vol 30. issue 7. 2016-04-04. PMID:26018615. |
balancing the basal ganglia circuitry: a possible new role for dopamine d2 receptors in health and disease. |
2016-04-04 |
2023-08-13 |
Not clear |
| Maxime Cazorla, Un Jung Kang, Christoph Kellendon. Balancing the basal ganglia circuitry: a possible new role for dopamine D2 receptors in health and disease. Movement disorders : official journal of the Movement Disorder Society. vol 30. issue 7. 2016-04-04. PMID:26018615. |
because dopamine d2 receptors and striatal neuron excitability have been found to regulate the density of bridging collaterals, we propose that targeting these projections downstream of d2 receptors could be a possible strategy for the treatment of basal ganglia disorders. |
2016-04-04 |
2023-08-13 |
Not clear |
| Agnieszka Ciesielska, Nitasha Sharma, Janine Beyer, John Forsayeth, Krystof Bankiewic. Carbidopa-based modulation of the functional effect of the AAV2-hAADC gene therapy in 6-OHDA lesioned rats. PloS one. vol 10. issue 4. 2016-03-31. PMID:25860990. |
this phenomenon is likely due to progressive loss of one of the key enzymes involved in the biosynthetic pathway for dopamine in the basal ganglia: aromatic l-amino acid decarboxylase (aadc). |
2016-03-31 |
2023-08-13 |
human |
| Osvaldo Ibáñez-Sandoval, Harry S Xenias, James M Tepper, Tibor Koó. Dopaminergic and cholinergic modulation of striatal tyrosine hydroxylase interneurons. Neuropharmacology. vol 95. 2016-03-24. PMID:25908399. |
powerful modulation of the nonlinear integrative properties of thins by dopamine and the direct depolarization of these neurons by acetylcholine may play important roles in mediating the effects of these neuromodulators in the neostriatum with potentially important implications for understanding the mechanisms of neuropsychiatric disorders affecting the basal ganglia. |
2016-03-24 |
2023-08-13 |
Not clear |
| Christopher B Divito, Kathy Steece-Collier, Daniel T Case, Sean-Paul G Williams, Jennifer A Stancati, Lianteng Zhi, Maria E Rubio, Caryl E Sortwell, Timothy J Collier, David Sulzer, Robert H Edwards, Hui Zhang, Rebecca P Sea. Loss of VGLUT3 Produces Circadian-Dependent Hyperdopaminergia and Ameliorates Motor Dysfunction and l-Dopa-Mediated Dyskinesias in a Model of Parkinson's Disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 45. 2016-02-22. PMID:26558771. |
the vesicular glutamate transporter 3 (vglut3) is expressed by striatal cholinergic interneurons (cins) and is thus well positioned to regulate dopamine (da) signaling and locomotor activity, a canonical measure of basal ganglia output. |
2016-02-22 |
2023-08-13 |
mouse |
| Daniel Lopatin, Nicole Caputo, Chelsey Damphousse, Siyaram Pandey, Jerome Cohe. Rats anticipate damaged rungs on the elevated ladder: Applications for rodent models of Parkinson's disease. Journal of integrative neuroscience. vol 14. issue 1. 2016-01-19. PMID:25747570. |
we discussed how traditional associative and cognitive theories of aversive conditioning account for these findings and their relationship to normal changes in dopamine production and possible effects of reduced production from the substantia nigra pars compacta (snpc) in the basal ganglia in rodent models of parkinson's disease. |
2016-01-19 |
2023-08-13 |
rat |
| Javier Baladron, Fred H Hamke. A spiking neural network based on the basal ganglia functional anatomy. Neural networks : the official journal of the International Neural Network Society. vol 67. 2015-12-18. PMID:25863288. |
we model learning in the three major basal ganglia pathways, direct, indirect and hyperdirect, by spike time dependent learning and considering the amount of dopamine available (reward). |
2015-12-18 |
2023-08-13 |
Not clear |
| Arun Singh, Li Liang, Yoshiki Kaneoke, Xuebing Cao, Stella M Pap. Dopamine regulates distinctively the activity patterns of striatal output neurons in advanced parkinsonian primates. Journal of neurophysiology. vol 113. issue 5. 2015-12-01. PMID:25505120. |
nigrostriatal dopamine denervation plays a major role in basal ganglia circuitry disarray and motor abnormalities of parkinson's disease (pd). |
2015-12-01 |
2023-08-13 |
monkey |
| I G Silki. [A Role of the Basal Ganglia in Processing of Complex Sounds and Auditory Attention]. Uspekhi fiziologicheskikh nauk. vol 46. issue 3. 2015-11-30. PMID:26506644. |
release of dopamine in the striatum promotes bidirectional modulation of strong and weak inputs from the neocortex to striatal neurons giving rise to direct and indirect pathways through the basal ganglia. |
2015-11-30 |
2023-08-13 |
Not clear |
| I G Silki. [A Role of the Basal Ganglia in Processing of Complex Sounds and Auditory Attention]. Uspekhi fiziologicheskikh nauk. vol 46. issue 3. 2015-11-30. PMID:26506644. |
it follows from this mechanism that involuntary attention to sound tone can enhance an early component of the responses of neurons in the primary auditory cortical area (50 msec) in the absence of dopamine due to a disinhibition of thalamic neurons via the direct pathway through the basal ganglia, whereas voluntary attention to complex sounds can enhance only those components of responses of neurones in secondary auditory cortical areas which latencies exceeds latencies of dopaminergic cells (i.e. |
2015-11-30 |
2023-08-13 |
Not clear |
| Julie E Miller, George W Hafzalla, Zachary D Burkett, Cynthia M Fox, Stephanie A Whit. Reduced vocal variability in a zebra finch model of dopamine depletion: implications for Parkinson disease. Physiological reports. vol 3. issue 11. 2015-11-13. PMID:26564062. |
midbrain dopamine (da) modulates the activity of basal ganglia circuitry important for motor control in a variety of species. |
2015-11-13 |
2023-08-13 |
Not clear |
| Anthony Bosson, Sylvie Boisseau, Alain Buisson, Marc Savasta, Mireille Albrieu. Disruption of dopaminergic transmission remodels tripartite synapse morphology and astrocytic calcium activity within substantia nigra pars reticulata. Glia. vol 63. issue 4. 2015-10-29. PMID:25511180. |
the substantia nigra pars reticulata (snr) is a major output nucleus of the basal ganglia circuitry particularly sensitive to pathological dopamine depletion. |
2015-10-29 |
2023-08-13 |
rat |
| Jae-Ick Kim, Subhashree Ganesan, Sarah X Luo, Yu-Wei Wu, Esther Park, Eric J Huang, Lu Chen, Jun B Din. Aldehyde dehydrogenase 1a1 mediates a GABA synthesis pathway in midbrain dopaminergic neurons. Science (New York, N.Y.). vol 350. issue 6256. 2015-10-28. PMID:26430123. |
midbrain dopamine neurons are an essential component of the basal ganglia circuitry, playing key roles in the control of fine movement and reward. |
2015-10-28 |
2023-08-13 |
Not clear |
| Gregory P Strauss, James A Waltz, James M Gol. A review of reward processing and motivational impairment in schizophrenia. Schizophrenia bulletin. vol 40 Suppl 2. 2015-10-23. PMID:24375459. |
aberrant cortical-striatal interactions may be involved with multiple reward processing abnormalities, including: (1) dopamine-mediated basal ganglia systems that support reinforcement learning and the ability to predict cues that lead to rewarding outcomes; (2) orbitofrontal cortex-driven deficits in generating, updating, and maintaining value representations; (3) aberrant effort-value computations, which may be mediated by disrupted anterior cingulate cortex and midbrain dopamine functioning; and (4) altered activation of the prefrontal cortex, which is important for generating exploratory behaviors in environments where reward outcomes are uncertain. |
2015-10-23 |
2023-08-12 |
Not clear |
| Henning Schroll, Christian Beste, Fred H Hamke. Combined lesions of direct and indirect basal ganglia pathways but not changes in dopamine levels explain learning deficits in patients with Huntington's disease. The European journal of neuroscience. vol 41. issue 9. 2015-10-12. PMID:25778633. |
combined lesions of direct and indirect basal ganglia pathways but not changes in dopamine levels explain learning deficits in patients with huntington's disease. |
2015-10-12 |
2023-08-13 |
human |