Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Sten Grillner, Arndt von Twickel, Brita Robertso. The blueprint of the vertebrate forebrain - With special reference to the habenulae. Seminars in cell & developmental biology. vol 78. 2018-12-11. PMID:29107476. |
the medial and lateral habenulae are conserved throughout vertebrate evolution, and form an integrated part in the forebrain control of behavior together with the basal ganglia, the dopamine and serotonin systems and cortex. |
2018-12-11 |
2023-08-13 |
Not clear |
Salvatore Galati, Wei Song, Gergely Orban, Andreas R Luft, Alain Kaelin-Lan. Cortical slow wave activity correlates with striatal synaptic strength in normal but not in Parkinsonian rats. Experimental neurology. vol 301. issue Pt A. 2018-10-24. PMID:29248630. |
urethane-induced cortical slow wave activity (swa) spreads into the basal ganglia in dopamine (da)-depleted rat models of parkinson's disease (pd). |
2018-10-24 |
2023-08-13 |
rat |
Naveed Malek, Ravi Jampana, Donald G Grosse. Rare case of atypical parkinsonism: why family history is important. Scottish medical journal. vol 62. issue 4. 2018-10-22. PMID:29192564. |
magnetic resonance imaging scan of the brain was normal and a dat spect scan showed reduced dopamine uptake in the basal ganglia. |
2018-10-22 |
2023-08-13 |
Not clear |
Jones G Parker, Jesse D Marshall, Biafra Ahanonu, Yu-Wei Wu, Tony Hyun Kim, Benjamin F Grewe, Yanping Zhang, Jin Zhong Li, Jun B Ding, Michael D Ehlers, Mark J Schnitze. Diametric neural ensemble dynamics in parkinsonian and dyskinetic states. Nature. vol 557. issue 7704. 2018-10-15. PMID:29720658. |
loss of dopamine in parkinson's disease is hypothesized to impede movement by inducing hypo- and hyperactivity in striatal spiny projection neurons (spns) of the direct (dspns) and indirect (ispns) pathways in the basal ganglia, respectively. |
2018-10-15 |
2023-08-13 |
mouse |
Giorgio Rizzi, Kelly R Ta. Dopamine and Acetylcholine, a Circuit Point of View in Parkinson's Disease. Frontiers in neural circuits. vol 11. 2018-09-27. PMID:29311846. |
this review covers some of the recent developments in the field of basal ganglia (bg) function in physiology and pathology, with a particular focus on the two main neuromodulatory systems known to be severely affected in pd, highlighting some of the remaining open question from three main stand points: - heterogeneity of midbrain dopamine neurons. |
2018-09-27 |
2023-08-13 |
Not clear |
Bhagwant R Mittal, Apurva Sood, Jaya Shukla, Rakhee Vatsa, Priya Bhusari, Ritu Shree, Sahil Mehta, Manoj Goyal, Manish Mod. 99mTc-TRODAT-1 SPECT/CT imaging as a complementary biomarker in the diagnosis of parkinsonian syndromes. Nuclear medicine communications. vol 39. issue 4. 2018-08-24. PMID:29381583. |
parkinson's disease (pd) and parkinson plus syndromes (pps) are neurodegenerative movement disorders caused by loss of dopamine in the basal ganglia. |
2018-08-24 |
2023-08-13 |
Not clear |
Luigi Trojano, Costanza Papagn. Cognitive and behavioral disorders in Parkinson's disease: an update. II: behavioral disorders. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 39. issue 1. 2018-08-15. PMID:29038946. |
symptoms can be present since early stages of the disease, sometimes even before the appearance of classical motor symptoms, likely in relation to dopamine depletion in basal ganglia and/or to dysfunctions of other neurotrasmitter systems, and others can develop later, in some cases in relation to dopaminergic treatment. |
2018-08-15 |
2023-08-13 |
Not clear |
Jeongjin Kim, Daesoo Ki. Rebound excitability mediates motor abnormalities in Parkinson's disease. BMB reports. vol 51. issue 1. 2018-08-15. PMID:29335072. |
in dopamine deficient state, the basal ganglia increases inhibitory synaptic outputs to the thalamus. |
2018-08-15 |
2023-08-13 |
mouse |
Mechelle M Lewis, Nicholas W Sterling, Guangwei Du, Eun-Young Lee, Grace Shyu, Michael Goldenberg, Thomas Allen, Christy Stetter, Lan Kong, Shedra Amy Snipes, Byron C Jones, Honglei Chen, Richard B Mailman, Xuemei Huan. Lateralized Basal Ganglia Vulnerability to Pesticide Exposure in Asymptomatic Agricultural Workers. Toxicological sciences : an official journal of the Society of Toxicology. vol 159. issue 1. 2018-06-19. PMID:28633499. |
pesticide exposure is linked to parkinson's disease, a neurodegenerative disorder marked by dopamine cell loss in the substantia nigra of the basal ganglia (bg) that often presents asymmetrically. |
2018-06-19 |
2023-08-13 |
Not clear |
Victor Mathis, Lucas Lecourtie. Role of the lateral habenula in memory through online processing of information. Pharmacology, biochemistry, and behavior. vol 162. 2018-06-18. PMID:28709783. |
animal research has recently attracted attention on the lateral habenula which, as shown in rodents and non-human primates, seems to process information stemming in the main regions involved in memory processing, e.g., the medial prefrontal cortex, the hippocampus, the amygdala, the septal region, the basal ganglia, and participates in the control of key memory-related neurotransmitters systems, i.e., dopamine, serotonin, acetylcholine. |
2018-06-18 |
2023-08-13 |
Not clear |
Brian Lau, Tiago Monteiro, Joseph J Pato. The many worlds hypothesis of dopamine prediction error: implications of a parallel circuit architecture in the basal ganglia. Current opinion in neurobiology. vol 46. 2018-06-11. PMID:28985550. |
the many worlds hypothesis of dopamine prediction error: implications of a parallel circuit architecture in the basal ganglia. |
2018-06-11 |
2023-08-13 |
Not clear |
Brian Lau, Tiago Monteiro, Joseph J Pato. The many worlds hypothesis of dopamine prediction error: implications of a parallel circuit architecture in the basal ganglia. Current opinion in neurobiology. vol 46. 2018-06-11. PMID:28985550. |
we focus on one important component of basal ganglia circuitry, midbrain dopamine neurons, drawing attention to data that has been cast as supporting or departing from the rl framework that has inspired experiments in basal ganglia research over the past two decades. |
2018-06-11 |
2023-08-13 |
Not clear |
Masahiko Tomiyam. [Symptoms and Pathophysiology of Dyskinesias]. Brain and nerve = Shinkei kenkyu no shinpo. vol 69. issue 12. 2018-06-08. PMID:29282344. |
the priming process involved in peak-dose dyskinesia is as follows: (1) marked fluctuation of dopamine concentration occurs in the synaptic clefts of striatal neurons after each levodopa dose, (2) cortico-striatal synapses of the striatal spiny neurons of the direct pathway become supersensitive, (3) there is increased production of gaba in the spiny neurons and excessive storage of gaba in their axon terminals, (4) following this, each dose of levodopa causes excessive release of gaba into the output nuclei of the basal ganglia, resulting in abnormal firing of the neurons in these nuclei. |
2018-06-08 |
2023-08-13 |
Not clear |
Regina Rumpel, Mesbah Alam, Lisa M Schwarz, Andreas Ratzka, Xingxing Jin, Joachim K Krauss, Claudia Grothe, Kerstin Schwab. Neuronal firing activity in the basal ganglia after striatal transplantation of dopamine neurons in hemiparkinsonian rats. Neuroscience. vol 360. 2018-06-05. PMID:28790019. |
neuronal firing activity in the basal ganglia after striatal transplantation of dopamine neurons in hemiparkinsonian rats. |
2018-06-05 |
2023-08-13 |
human |
Regina Rumpel, Mesbah Alam, Lisa M Schwarz, Andreas Ratzka, Xingxing Jin, Joachim K Krauss, Claudia Grothe, Kerstin Schwab. Neuronal firing activity in the basal ganglia after striatal transplantation of dopamine neurons in hemiparkinsonian rats. Neuroscience. vol 360. 2018-06-05. PMID:28790019. |
the loss of nigral dopaminergic neurons and the resulting dopamine (da) depletion in the striatum (str) lead to altered neuronal activity and enhanced beta activity in various regions of the basal ganglia (bg) motor loop in patients with parkinson's disease and in rodents in the 6-hydroxydopamine (6-ohda)-lesioned rat model. |
2018-06-05 |
2023-08-13 |
human |
Witold J Lipski, Sofia M Dibble, Linda Rinaman, Anthony A Grac. Psychogenic Stress Activates C-Fos in Nucleus Accumbens-Projecting Neurons of the Hippocampal Ventral Subiculum. The international journal of neuropsychopharmacology. vol 20. issue 10. 2018-06-05. PMID:28977522. |
artificial activation of the ventral subiculum can excite medium spiny neurons of the nucleus accumbens and can increase the excitability of mesolimbic dopamine neurons via a polysynaptic pathway through the basal ganglia. |
2018-06-05 |
2023-08-13 |
Not clear |
Maribel Pérez-Rodríguez, Esperanza García-Mendoza, Eunice D Farfán-García, Bhaskar C Das, Fabiola J Ciprés-Flores, José G Trujillo-Ferrara, Feliciano Tamay-Cach, Marvin A Soriano-Ursú. Not all boronic acids with a five-membered cycle induce tremor, neuronal damage and decreased dopamine. Neurotoxicology. vol 62. 2018-05-30. PMID:28595910. |
the various manifestations generated by these compounds can be linked, in part, to different levels of dopamine (measured by hplc) and degrees of neuronal damage in the basal ganglia and cerebellum. |
2018-05-30 |
2023-08-13 |
mouse |
Agata Budzillo, Alison Duffy, Kimberly E Miller, Adrienne L Fairhall, David J Perke. Dopaminergic modulation of basal ganglia output through coupled excitation-inhibition. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 22. 2018-05-15. PMID:28507134. |
dopamine in the basal ganglia reduces trial-to-trial neural variability when the bird engages in courtship song. |
2018-05-15 |
2023-08-13 |
Not clear |
Ivan Carrera, Lucia Fernandez-Novoa, Carolina Sampedro, Ramon Cacabelo. Neuroprotective Effect of Atremorine in an Experimental Model of Parkinson's Disease. Current pharmaceutical design. vol 23. issue 18. 2018-05-09. PMID:28190394. |
data demonstrated that atremorine promotes neuroprotection and behavior recovery in the injured mtpt-mouse brain by modulating the expression levels of tyrosine hydroxylase, glial proteins, apoptosis and endogenous dopamine and neuromelanin concentrations, probably the key to recover the basal ganglia function. |
2018-05-09 |
2023-08-13 |
mouse |
Jaishree Jalewa, Mohit Kumar Sharma, Simon Gengler, Christian Hölsche. A novel GLP-1/GIP dual receptor agonist protects from 6-OHDA lesion in a rat model of Parkinson's disease. Neuropharmacology. vol 117. 2018-05-03. PMID:28223210. |
dopamine levels in the basal ganglia were reduced by 6-ohda lesion and increased by da-jc1. |
2018-05-03 |
2023-08-13 |
mouse |