| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vishal Rawji, Lorenzo Rocchi, Tom Foltynie, John C Rothwell, Marjan Jahanshah. Ropinirole, a dopamine agonist with high D Neuropharmacology. vol 179. 2021-08-27. PMID:32827517. |
dopamine has been posed as a candidate mediator of response inhibition due to its role in functioning of the basal ganglia and the observation that patients with parkinson's disease on dopamine agonists develop impulse control disorders. |
2021-08-27 |
2023-08-13 |
human |
| Adjia Hamadjida, Stephen G Nuara, Imane Frouni, Cynthia Kwan, Dominique Bédard, Jim C Gourdon, Philippe Huo. Monoamine oxidase A inhibition as monotherapy reverses parkinsonism in the MPTP-lesioned marmoset. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 11. 2021-08-26. PMID:32601846. |
here, we explore the anti-parkinsonian effect of mao type a (mao-a) inhibition as monotherapy, as the enzyme mao-a is also encountered within the primate and human basal ganglia, where it metabolises dopamine, albeit to a lesser extent than mao-b. |
2021-08-26 |
2023-08-13 |
human |
| Yuksel Caki. Computational neuronal correlation with enhanced synchronized activity in the basal ganglia and the slowing of thalamic theta and alpha rhythms in Parkinson's disease. The European journal of neuroscience. vol 54. issue 3. 2021-08-23. PMID:34192822. |
the aim of this work is computationally to correlate the synchronized neuronal activity of basal ganglia and slowing in theta and alpha rhythms in electroencephalogram (eeg) signal in thalamic region in case of dopamine depletion and decrease of synaptic connections. |
2021-08-23 |
2023-08-13 |
Not clear |
| Yuksel Caki. Computational neuronal correlation with enhanced synchronized activity in the basal ganglia and the slowing of thalamic theta and alpha rhythms in Parkinson's disease. The European journal of neuroscience. vol 54. issue 3. 2021-08-23. PMID:34192822. |
depending on the decrease of synaptic connections and dopamine level, the synchronization among basal ganglia neuron populations is investigated. |
2021-08-23 |
2023-08-13 |
Not clear |
| Elisa Frisaldi, Aziz Shaibani, Fabrizio Benedett. Understanding the mechanisms of placebo and nocebo effects. Swiss medical weekly. vol 150. 2021-08-18. PMID:32920787. |
in these medical conditions the neural networks involved have indeed been identified: that is, opioid, cannabinoid, cholecystokinin, cyclooxygenase, and dopamine modulatory networks in pain; and part of the basal ganglia circuitry in parkinson’s disease. |
2021-08-18 |
2023-08-13 |
human |
| Florence Véronneau-Veilleux, Mauro Ursino, Philippe Robaey, Daniel Lévesque, Fahima Nekk. Nonlinear pharmacodynamics of levodopa through Parkinson's disease progression. Chaos (Woodbury, N.Y.). vol 30. issue 9. 2021-08-18. PMID:33003902. |
using a holistic approach, a pharmacokinetic model of levodopa was combined to a dopamine dynamics and a neurocomputational model of basal ganglia. |
2021-08-18 |
2023-08-13 |
Not clear |
| A N Woo. New roles for dopamine in motor skill acquisition: lessons from primates, rodents, and songbirds. Journal of neurophysiology. vol 125. issue 6. 2021-08-17. PMID:33978497. |
mesencephalic dopamine structures are highly conserved among vertebrates, as are some of their primary targets within the basal ganglia, a subcortical circuit important for motor learning and motor control. |
2021-08-17 |
2023-08-13 |
human |
| A N Woo. New roles for dopamine in motor skill acquisition: lessons from primates, rodents, and songbirds. Journal of neurophysiology. vol 125. issue 6. 2021-08-17. PMID:33978497. |
the hypotheses that dopamine could drive motor learning either by functioning as a reward prediction error, through passive facilitating of normal basal ganglia activity, or through other mechanisms are examined in light of new studies using humans, rodents, and songbirds. |
2021-08-17 |
2023-08-13 |
human |
| Eva M Navarro-López, Utku Çelikok, Neslihan S Şengö. A dynamical model for the basal ganglia-thalamo-cortical oscillatory activity and its implications in Parkinson's disease. Cognitive neurodynamics. vol 15. issue 4. 2021-08-10. PMID:34367369. |
the model uniquely unifies the influence of dopamine in the regulation of the activity of all basal ganglia nuclei, the self-organised neuronal interdependent activity of basal ganglia-thalamo-cortical circuits and the generation of subcortical background oscillations. |
2021-08-10 |
2023-08-13 |
Not clear |
| Eva M Navarro-López, Utku Çelikok, Neslihan S Şengö. A dynamical model for the basal ganglia-thalamo-cortical oscillatory activity and its implications in Parkinson's disease. Cognitive neurodynamics. vol 15. issue 4. 2021-08-10. PMID:34367369. |
variations in the amount of dopamine produced in the neurons of the substantia nigra pars compacta are key both in the onset of parkinson's disease and in the basal ganglia action selection. |
2021-08-10 |
2023-08-13 |
Not clear |
| Eva M Navarro-López, Utku Çelikok, Neslihan S Şengö. A dynamical model for the basal ganglia-thalamo-cortical oscillatory activity and its implications in Parkinson's disease. Cognitive neurodynamics. vol 15. issue 4. 2021-08-10. PMID:34367369. |
these results are significant because: (1) the neural populations are built upon single-neuron models that have been robustly designed to have eletrophysiologically-realistic responses, and (2) our model distinctively links changes in the oscillatory activity in subcortical structures, dopamine levels in the basal ganglia and pathological synchronisation neuronal patterns compatible with parkinsonian states, this still remains an open problem and is crucial to better understand the progression of the disease. |
2021-08-10 |
2023-08-13 |
Not clear |
| Angel A Robles-Gómez, Ana V Vega, Benjamín Florán, Jaime Barra. Differential calcium channel-mediated dopaminergic modulation in the subthalamonigral synapse. Synapse (New York, N.Y.). vol 74. issue 7. 2021-08-09. PMID:31975491. |
dopamine (da) modulates basal ganglia (bg) activity for initiation and execution of goal-directed movements and habits. |
2021-08-09 |
2023-08-13 |
Not clear |
| Lilach Gorodetski, Yocheved Loewenstern, Anna Faynveitz, Izhar Bar-Gad, Kim T Blackwell, Alon Korngree. Endocannabinoids and Dopamine Balance Basal Ganglia Output. Frontiers in cellular neuroscience. vol 15. 2021-07-31. PMID:33815062. |
endocannabinoids and dopamine balance basal ganglia output. |
2021-07-31 |
2023-08-13 |
Not clear |
| Jie Dong, Sarah Hawes, Junbing Wu, Weidong Le, Huaibin Ca. Connectivity and Functionality of the Globus Pallidus Externa Under Normal Conditions and Parkinson's Disease. Frontiers in neural circuits. vol 15. 2021-07-16. PMID:33737869. |
impairments in dopamine transmission in the basal ganglia contribute to parkinson's disease (pd), the most common movement disorder that severely affects the patients' life quality. |
2021-07-16 |
2023-08-13 |
Not clear |
| Bruk Getachew, Antonei B Csoka, Amna Bhatti, Robert L Copeland, Yousef Tizab. Butyrate Protects Against Salsolinol-Induced Toxicity in SH-SY5Y Cells: Implication for Parkinson's Disease. Neurotoxicity research. vol 38. issue 3. 2021-07-09. PMID:32572814. |
parkinson's disease (pd), a progressive neurodegenerative disorder, is associated with the destruction of dopamine neurons in the substantia nigra (sn) and the formation of lewy bodies in basal ganglia. |
2021-07-09 |
2023-08-13 |
human |
| Yiqiu Liu, Junyu Deng, Ye Liu, Wei Li, Xuqiang Ni. FGF, Mechanism of Action, Role in Parkinson's Disease, and Therapeutics. Frontiers in pharmacology. vol 12. 2021-07-09. PMID:34234672. |
the death or dysfunction of dopaminergic neurons in the dense part of the substantia nigra leads to dopamine deficiency in the basal ganglia and motor dysfunction. |
2021-07-09 |
2023-08-13 |
Not clear |
| Giacomo Sitzia, Ioannis Mantas, Xiaoqun Zhang, Per Svenningsson, Karima Chergu. NMDA receptors are altered in the substantia nigra pars reticulata and their blockade ameliorates motor deficits in experimental parkinsonism. Neuropharmacology. vol 174. 2021-07-07. PMID:32474027. |
in parkinson's disease (pd) reduced levels of dopamine (da) in the striatum lead to an abnormal circuit activity of the basal ganglia and an increased output through the substantia nigra pars reticulata (snr) and the globus pallidus internal part. |
2021-07-07 |
2023-08-13 |
mouse |
| Tameem M Al-Ozzi, Luis F Botero-Posada, Adriana L Lopez Rios, William D Hutchiso. Single unit and beta oscillatory activities in subthalamic nucleus are modulated during visual choice preference. The European journal of neuroscience. vol 53. issue 7. 2021-06-29. PMID:32378745. |
parkinson's disease is a neurodegenerative disease affecting the supply of dopamine to basal ganglia nuclei, leading to pathological beta band (13-35 hz) oscillations in the subthalamic nucleus (stn). |
2021-06-29 |
2023-08-13 |
mouse |
| Robert Lindroos, Jeanette Hellgren Kotalesk. Predicting complex spikes in striatal projection neurons of the direct pathway following neuromodulation by acetylcholine and dopamine. The European journal of neuroscience. vol 53. issue 7. 2021-06-29. PMID:32609903. |
the input structure of the basal ganglia, striatum, receives dense neuromodulatory input in the form of dopamine and acetylcholine. |
2021-06-29 |
2023-08-13 |
Not clear |
| Tom Gilbertson, Douglas Steel. Tonic dopamine, uncertainty and basal ganglia action selection. Neuroscience. vol 466. 2021-06-22. PMID:34015370. |
tonic dopamine, uncertainty and basal ganglia action selection. |
2021-06-22 |
2023-08-13 |
Not clear |