| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A N Woo. New roles for dopamine in motor skill acquisition: lessons from primates, rodents, and songbirds. Journal of neurophysiology. vol 125. issue 6. 2021-08-17. PMID:33978497. |
mesencephalic dopamine structures are highly conserved among vertebrates, as are some of their primary targets within the basal ganglia, a subcortical circuit important for motor learning and motor control. |
2021-08-17 |
2023-08-13 |
human |
| A N Woo. New roles for dopamine in motor skill acquisition: lessons from primates, rodents, and songbirds. Journal of neurophysiology. vol 125. issue 6. 2021-08-17. PMID:33978497. |
the hypotheses that dopamine could drive motor learning either by functioning as a reward prediction error, through passive facilitating of normal basal ganglia activity, or through other mechanisms are examined in light of new studies using humans, rodents, and songbirds. |
2021-08-17 |
2023-08-13 |
human |
| Eva M Navarro-López, Utku Çelikok, Neslihan S Şengö. A dynamical model for the basal ganglia-thalamo-cortical oscillatory activity and its implications in Parkinson's disease. Cognitive neurodynamics. vol 15. issue 4. 2021-08-10. PMID:34367369. |
the model uniquely unifies the influence of dopamine in the regulation of the activity of all basal ganglia nuclei, the self-organised neuronal interdependent activity of basal ganglia-thalamo-cortical circuits and the generation of subcortical background oscillations. |
2021-08-10 |
2023-08-13 |
Not clear |
| Eva M Navarro-López, Utku Çelikok, Neslihan S Şengö. A dynamical model for the basal ganglia-thalamo-cortical oscillatory activity and its implications in Parkinson's disease. Cognitive neurodynamics. vol 15. issue 4. 2021-08-10. PMID:34367369. |
variations in the amount of dopamine produced in the neurons of the substantia nigra pars compacta are key both in the onset of parkinson's disease and in the basal ganglia action selection. |
2021-08-10 |
2023-08-13 |
Not clear |
| Eva M Navarro-López, Utku Çelikok, Neslihan S Şengö. A dynamical model for the basal ganglia-thalamo-cortical oscillatory activity and its implications in Parkinson's disease. Cognitive neurodynamics. vol 15. issue 4. 2021-08-10. PMID:34367369. |
these results are significant because: (1) the neural populations are built upon single-neuron models that have been robustly designed to have eletrophysiologically-realistic responses, and (2) our model distinctively links changes in the oscillatory activity in subcortical structures, dopamine levels in the basal ganglia and pathological synchronisation neuronal patterns compatible with parkinsonian states, this still remains an open problem and is crucial to better understand the progression of the disease. |
2021-08-10 |
2023-08-13 |
Not clear |
| Angel A Robles-Gómez, Ana V Vega, Benjamín Florán, Jaime Barra. Differential calcium channel-mediated dopaminergic modulation in the subthalamonigral synapse. Synapse (New York, N.Y.). vol 74. issue 7. 2021-08-09. PMID:31975491. |
dopamine (da) modulates basal ganglia (bg) activity for initiation and execution of goal-directed movements and habits. |
2021-08-09 |
2023-08-13 |
Not clear |
| Lilach Gorodetski, Yocheved Loewenstern, Anna Faynveitz, Izhar Bar-Gad, Kim T Blackwell, Alon Korngree. Endocannabinoids and Dopamine Balance Basal Ganglia Output. Frontiers in cellular neuroscience. vol 15. 2021-07-31. PMID:33815062. |
endocannabinoids and dopamine balance basal ganglia output. |
2021-07-31 |
2023-08-13 |
Not clear |
| Jie Dong, Sarah Hawes, Junbing Wu, Weidong Le, Huaibin Ca. Connectivity and Functionality of the Globus Pallidus Externa Under Normal Conditions and Parkinson's Disease. Frontiers in neural circuits. vol 15. 2021-07-16. PMID:33737869. |
impairments in dopamine transmission in the basal ganglia contribute to parkinson's disease (pd), the most common movement disorder that severely affects the patients' life quality. |
2021-07-16 |
2023-08-13 |
Not clear |
| Bruk Getachew, Antonei B Csoka, Amna Bhatti, Robert L Copeland, Yousef Tizab. Butyrate Protects Against Salsolinol-Induced Toxicity in SH-SY5Y Cells: Implication for Parkinson's Disease. Neurotoxicity research. vol 38. issue 3. 2021-07-09. PMID:32572814. |
parkinson's disease (pd), a progressive neurodegenerative disorder, is associated with the destruction of dopamine neurons in the substantia nigra (sn) and the formation of lewy bodies in basal ganglia. |
2021-07-09 |
2023-08-13 |
human |
| Yiqiu Liu, Junyu Deng, Ye Liu, Wei Li, Xuqiang Ni. FGF, Mechanism of Action, Role in Parkinson's Disease, and Therapeutics. Frontiers in pharmacology. vol 12. 2021-07-09. PMID:34234672. |
the death or dysfunction of dopaminergic neurons in the dense part of the substantia nigra leads to dopamine deficiency in the basal ganglia and motor dysfunction. |
2021-07-09 |
2023-08-13 |
Not clear |
| Giacomo Sitzia, Ioannis Mantas, Xiaoqun Zhang, Per Svenningsson, Karima Chergu. NMDA receptors are altered in the substantia nigra pars reticulata and their blockade ameliorates motor deficits in experimental parkinsonism. Neuropharmacology. vol 174. 2021-07-07. PMID:32474027. |
in parkinson's disease (pd) reduced levels of dopamine (da) in the striatum lead to an abnormal circuit activity of the basal ganglia and an increased output through the substantia nigra pars reticulata (snr) and the globus pallidus internal part. |
2021-07-07 |
2023-08-13 |
mouse |
| Tameem M Al-Ozzi, Luis F Botero-Posada, Adriana L Lopez Rios, William D Hutchiso. Single unit and beta oscillatory activities in subthalamic nucleus are modulated during visual choice preference. The European journal of neuroscience. vol 53. issue 7. 2021-06-29. PMID:32378745. |
parkinson's disease is a neurodegenerative disease affecting the supply of dopamine to basal ganglia nuclei, leading to pathological beta band (13-35 hz) oscillations in the subthalamic nucleus (stn). |
2021-06-29 |
2023-08-13 |
mouse |
| Robert Lindroos, Jeanette Hellgren Kotalesk. Predicting complex spikes in striatal projection neurons of the direct pathway following neuromodulation by acetylcholine and dopamine. The European journal of neuroscience. vol 53. issue 7. 2021-06-29. PMID:32609903. |
the input structure of the basal ganglia, striatum, receives dense neuromodulatory input in the form of dopamine and acetylcholine. |
2021-06-29 |
2023-08-13 |
Not clear |
| Tom Gilbertson, Douglas Steel. Tonic dopamine, uncertainty and basal ganglia action selection. Neuroscience. vol 466. 2021-06-22. PMID:34015370. |
tonic dopamine, uncertainty and basal ganglia action selection. |
2021-06-22 |
2023-08-13 |
Not clear |
| Tom Gilbertson, Douglas Steel. Tonic dopamine, uncertainty and basal ganglia action selection. Neuroscience. vol 466. 2021-06-22. PMID:34015370. |
using a computational model of the basal ganglia, we propose that switches between exploratory and exploitative decisions are mediated by the interaction between tonic dopamine and cortical input to the basal ganglia. |
2021-06-22 |
2023-08-13 |
Not clear |
| Sara M Green, Sanya Nathani, Joseph Zimmerman, David Fireman, Nikhil M Ur. Retrograde Labeling Illuminates Distinct Topographical Organization of D1 and D2 Receptor-Positive Pyramidal Neurons in the Prefrontal Cortex of Mice. eNeuro. vol 7. issue 5. 2021-06-18. PMID:33037031. |
thus, our data are the first to highlight a unique dopamine receptor-specific topographical pattern in the pfc, which could have profound implications for corticostriatal signaling in the basal ganglia. |
2021-06-18 |
2023-08-13 |
mouse |
| Aristide Merola, Amber Van Laar, Russell Lonser, Krzysztof Bankiewic. Gene therapy for Parkinson's disease: contemporary practice and emerging concepts. Expert review of neurotherapeutics. vol 20. issue 6. 2021-05-17. PMID:32425079. |
several gene therapy clinical trials have been conducted in parkinson's disease (pd) by exploring strategies to either restore dopamine synthesis, enhance the production of trophic factors, enhance lysosomal function, or modify the interaction between different functional nodes of the basal ganglia. |
2021-05-17 |
2023-08-13 |
Not clear |
| Toru Nakamura, Luis Carl Rios, Takeshi Yagi, Toshikuni Sasaoka, Takashi Kitsukaw. Dopamine D1 and muscarinic acetylcholine receptors in dorsal striatum are required for high speed running. Neuroscience research. vol 156. 2021-05-14. PMID:31812651. |
dopamine (da) signaling in the basal ganglia plays important roles in motor control. |
2021-05-14 |
2023-08-13 |
mouse |
| Farhan Augustine, Shreenath Rajendran, Harvey S Singe. Cortical endogenous opioids and their role in facilitating repetitive behaviors in deer mice. Behavioural brain research. vol 379. 2021-04-30. PMID:31676208. |
in this study, we pursue the mechanism of repetitive behaviors by performing stereological analyses and liquid chromatography/ mass spectrometry (lc-ms/ms) measurements of glutamate (glut), gaba, 3,4-dihydroxyphenylacetic acid (dopac), dopamine (da), leu-enkephalin (leu-enk), and dynorphin-a (dyn-a) in frontal cortex (fc), prefrontal cortex (pfc), and basal ganglia. |
2021-04-30 |
2023-08-13 |
mouse |
| Zahra Jafari, Bryan E Kolb, Majid H Mohajeran. Auditory Dysfunction in Parkinson's Disease. Movement disorders : official journal of the Movement Disorder Society. vol 35. issue 4. 2021-04-27. PMID:32052894. |
improvement in auditory responses following dopaminergic therapies also indicates the presence of similar neurotransmitters (i.e., glutamate and dopamine) in the auditory system and basal ganglia. |
2021-04-27 |
2023-08-13 |
Not clear |