| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Deransart, G B Landwehrmeyer, T J Feuerstein, C H Lückin. Up-regulation of D3 dopaminergic receptor mRNA in the core of the nucleus accumbens accompanies the development of seizures in a genetic model of absence-epilepsy in the rat. Brain research. Molecular brain research. vol 94. issue 1-2. 2002-01-03. PMID:11597777. |
the basal ganglia system is thought to play a key role in the control of absence-seizures and there is ample evidence that epileptic seizures modify brain dopamine function. |
2002-01-03 |
2023-08-12 |
rat |
| Z Zhang, A Andersen, R Grondin, T Barber, R Avison, G Gerhardt, D Gas. Pharmacological MRI mapping of age-associated changes in basal ganglia circuitry of awake rhesus monkeys. NeuroImage. vol 14. issue 5. 2002-01-02. PMID:11697947. |
while the pathophysiological changes induced by the loss of dopamine innervation in the basal ganglia by parkinson's disease (pd) are well studied, little is known about functional changes in the neural circuitry of this area during normal aging. |
2002-01-02 |
2023-08-12 |
monkey |
| J C Villares, J N Staval. Age-related changes in the N-methyl-D-aspartate receptor binding sites within the human basal ganglia. Experimental neurology. vol 171. issue 2. 2001-12-05. PMID:11573991. |
these results demonstrate that the basal ganglia have age-associated reductions in dopamine transporter uptake and nmda receptors. |
2001-12-05 |
2023-08-12 |
human |
| J C Villares, J N Staval. Age-related changes in the N-methyl-D-aspartate receptor binding sites within the human basal ganglia. Experimental neurology. vol 171. issue 2. 2001-12-05. PMID:11573991. |
the dopamine transporter uptake and nmda receptors appear to be vulnerable to the aging process in the basal ganglia. |
2001-12-05 |
2023-08-12 |
human |
| G Conti, F Blandini, C Tassorelli, F Giubilei, F Fornai, A Zocchi, F Orz. Intrastriatal injection of D1 or D2 dopamine agonists affects glucose utilization in both the direct and indirect pathways of the rat basal ganglia. Neuroscience letters. vol 309. issue 3. 2001-12-04. PMID:11514066. |
intrastriatal injection of d1 or d2 dopamine agonists affects glucose utilization in both the direct and indirect pathways of the rat basal ganglia. |
2001-12-04 |
2023-08-12 |
rat |
| G Conti, F Blandini, C Tassorelli, F Giubilei, F Fornai, A Zocchi, F Orz. Intrastriatal injection of D1 or D2 dopamine agonists affects glucose utilization in both the direct and indirect pathways of the rat basal ganglia. Neuroscience letters. vol 309. issue 3. 2001-12-04. PMID:11514066. |
two distinct pathways are thought to connect the striatum to the basal ganglia output nuclei: a direct pathway, originating from neurons bearing dopamine, d(1) receptors and an indirect pathway, originating from neurons expressing d(2) receptors. |
2001-12-04 |
2023-08-12 |
rat |
| R R Gainetdinov, A R Mohn, L M Bohn, M G Caro. Glutamatergic modulation of hyperactivity in mice lacking the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 20. 2001-12-04. PMID:11572967. |
these findings support the concept of a reciprocal functional interaction between dopamine and glutamate in the basal ganglia and suggest that agents modulating glutamatergic transmission may represent an approach to manage conditions associated with dopaminergic dysfunction. |
2001-12-04 |
2023-08-12 |
mouse |
| J W Min. Basal ganglia dysfunction in Tourette's syndrome: a new hypothesis. Pediatric neurology. vol 25. issue 3. 2001-12-04. PMID:11587872. |
the functional anatomy of basal ganglia circuits and new information on dopamine modulation of those circuits provide the basis for hypotheses of basal ganglia dysfunction in tourette's syndrome. |
2001-12-04 |
2023-08-12 |
Not clear |
| C C Chiue. Iron overload, oxidative stress, and axonal dystrophy in brain disorders. Pediatric neurology. vol 25. issue 2. 2001-10-25. PMID:11551744. |
an increase of oxidative stress in the basal ganglia because of redox cycling of iron complexes leads to dopamine overflow and psychomotor dysfunction. |
2001-10-25 |
2023-08-12 |
Not clear |
| A Gjedd. [Receptor mapping in living human beings by means of positron emission tomography]. Ugeskrift for laeger. vol 163. issue 38. 2001-10-25. PMID:11577527. |
dopamine tracers are used in diseases of the basal ganglia, whereas serotonin, benzodiazepine, and opiate tracers are used in lesions of the cerebral cortex. |
2001-10-25 |
2023-08-12 |
human |
| Z Ni, D Gao, R Bouali-Benazzouz, A L Benabid, A Benazzou. Effect of microiontophoretic application of dopamine on subthalamic nucleus neuronal activity in normal rats and in rats with unilateral lesion of the nigrostriatal pathway. The European journal of neuroscience. vol 14. issue 2. 2001-10-11. PMID:11553287. |
these results show that dopamine exerts an excitatory influence on stn neurons, suggesting that the inhibitory effect induced by the systemic injection of apomorphine is due to the gabaergic inputs from the globus pallidus as predicted by the current model of basal ganglia organization. |
2001-10-11 |
2023-08-12 |
rat |
| M Quik, Y Polonskaya, J M Kulak, J M McIntos. Vulnerability of 125I-alpha-conotoxin MII binding sites to nigrostriatal damage in monkey. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 15. 2001-08-16. PMID:11466420. |
autoradiographic analysis showed that (125)i-alpha-ctxmii sites were selectively reduced (>/=99%) in the basal ganglia and that the lesion-induced decreases correlated well with declines in the dopamine transporter, a marker of dopaminergic neuron integrity. |
2001-08-16 |
2023-08-12 |
monkey |
| E C Clark, L R Baxter, L S Dure, R F Ackermann, G F Kemp, S E Bachu. Mammal-like striatal functions in Anolis. II. Distribution of dopamine D(1) and D(2) receptors, and a laminar pattern of basal ganglia sub-systems. Brain, behavior and evolution. vol 56. issue 5. 2001-07-05. PMID:11251317. |
distribution of dopamine d(1) and d(2) receptors, and a laminar pattern of basal ganglia sub-systems. |
2001-07-05 |
2023-08-12 |
Not clear |
| M J Hurley, D C Mash, P Jenne. Dopamine D(1) receptor expression in human basal ganglia and changes in Parkinson's disease. Brain research. Molecular brain research. vol 87. issue 2. 2001-06-28. PMID:11245931. |
dopamine d(1) receptor expression in human basal ganglia and changes in parkinson's disease. |
2001-06-28 |
2023-08-12 |
human |
| M I López-Ibor Alcocer, T Ortiz Alonso, M Encinas Mejías, A Fernández, F Maestú, J J López-Ibor Aliñ. [New advances in neuroimaging in the diagnosis of obsessive-compulsive disorder]. Actas espanolas de psiquiatria. vol 28. issue 5. 2001-06-07. PMID:11269909. |
given the basal ganglia receive such rich innervation from both 5-th and dopamine neurones, it has been postulated that ocd is subserved by a neuronal dysfunction in the basal ganglia and orbitofrontal cortex circuit. |
2001-06-07 |
2023-08-12 |
human |
| I Silki. The cortico-basal ganglia-thalamocortical circuit with synaptic plasticity. II. Mechanism of synergistic modulation of thalamic activity via the direct and indirect pathways through the basal ganglia. Bio Systems. vol 59. issue 1. 2001-05-24. PMID:11226622. |
a possible mechanism underlying the modulatory role of dopamine, adenosine and acetylcholine in the modification of corticostriatal synapses, subsequent changes in signal transduction through the "direct" and "indirect" pathways in the basal ganglia and variations in thalamic and neocortical cell activity is proposed. |
2001-05-24 |
2023-08-12 |
Not clear |
| E Bezard, A R Crossman, C E Gross, J M Brotchi. Structures outside the basal ganglia may compensate for dopamine loss in the presymptomatic stages of Parkinson's disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 15. issue 6. 2001-05-10. PMID:11292678. |
structures outside the basal ganglia may compensate for dopamine loss in the presymptomatic stages of parkinson's disease. |
2001-05-10 |
2023-08-12 |
Not clear |
| K Tang, M J Low, D K Grandy, D M Lovinge. Dopamine-dependent synaptic plasticity in striatum during in vivo development. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 3. 2001-04-12. PMID:11158626. |
the neurotransmitters dopamine (da) and glutamate in the striatum play key roles in movement and cognition, and they are implicated in disorders of the basal ganglia such as parkinson's disease. |
2001-04-12 |
2023-08-12 |
Not clear |
| T Boraud, E Bezard, B Bioulac, C E Gros. Dopamine agonist-induced dyskinesias are correlated to both firing pattern and frequency alterations of pallidal neurones in the MPTP-treated monkey. Brain : a journal of neurology. vol 124. issue Pt 3. 2001-04-05. PMID:11222455. |
in this study, electrophysiological single-unit recordings of the neuronal activity of the globus pallidus internalis (gpi), the main basal ganglia output structure, and the globus pallidus externalis (gpe) were recorded continuously in both normal and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treated subhuman primates before and after the administration of three dopamine agonists--apomorphine (a dopaminergic mixed agonist), skf-38393 (a d1 partial agonist) and piribedil (a d2/d3 agonist)--at doses known to induce dyskinesias in the parkinsonian monkey. |
2001-04-05 |
2023-08-12 |
monkey |
| b' J C Corvol, J M Studler, J S Schonn, J A Girault, D Herv\\xc3\\xa. Galpha(olf) is necessary for coupling D1 and A2a receptors to adenylyl cyclase in the striatum. Journal of neurochemistry. vol 76. issue 5. 2001-04-05. PMID:11238742.' |
together, these results identify galpha(olf) as a critical parameter in the responses to dopamine and adenosine in the basal ganglia. |
2001-04-05 |
2023-08-12 |
mouse |