| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R R Gainetdinov, A R Mohn, L M Bohn, M G Caro. Glutamatergic modulation of hyperactivity in mice lacking the dopamine transporter. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 20. 2001-12-04. PMID:11572967. |
these findings support the concept of a reciprocal functional interaction between dopamine and glutamate in the basal ganglia and suggest that agents modulating glutamatergic transmission may represent an approach to manage conditions associated with dopaminergic dysfunction. |
2001-12-04 |
2023-08-12 |
mouse |
| J W Min. Basal ganglia dysfunction in Tourette's syndrome: a new hypothesis. Pediatric neurology. vol 25. issue 3. 2001-12-04. PMID:11587872. |
the functional anatomy of basal ganglia circuits and new information on dopamine modulation of those circuits provide the basis for hypotheses of basal ganglia dysfunction in tourette's syndrome. |
2001-12-04 |
2023-08-12 |
Not clear |
| C C Chiue. Iron overload, oxidative stress, and axonal dystrophy in brain disorders. Pediatric neurology. vol 25. issue 2. 2001-10-25. PMID:11551744. |
an increase of oxidative stress in the basal ganglia because of redox cycling of iron complexes leads to dopamine overflow and psychomotor dysfunction. |
2001-10-25 |
2023-08-12 |
Not clear |
| A Gjedd. [Receptor mapping in living human beings by means of positron emission tomography]. Ugeskrift for laeger. vol 163. issue 38. 2001-10-25. PMID:11577527. |
dopamine tracers are used in diseases of the basal ganglia, whereas serotonin, benzodiazepine, and opiate tracers are used in lesions of the cerebral cortex. |
2001-10-25 |
2023-08-12 |
human |
| Z Ni, D Gao, R Bouali-Benazzouz, A L Benabid, A Benazzou. Effect of microiontophoretic application of dopamine on subthalamic nucleus neuronal activity in normal rats and in rats with unilateral lesion of the nigrostriatal pathway. The European journal of neuroscience. vol 14. issue 2. 2001-10-11. PMID:11553287. |
these results show that dopamine exerts an excitatory influence on stn neurons, suggesting that the inhibitory effect induced by the systemic injection of apomorphine is due to the gabaergic inputs from the globus pallidus as predicted by the current model of basal ganglia organization. |
2001-10-11 |
2023-08-12 |
rat |
| M Quik, Y Polonskaya, J M Kulak, J M McIntos. Vulnerability of 125I-alpha-conotoxin MII binding sites to nigrostriatal damage in monkey. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 15. 2001-08-16. PMID:11466420. |
autoradiographic analysis showed that (125)i-alpha-ctxmii sites were selectively reduced (>/=99%) in the basal ganglia and that the lesion-induced decreases correlated well with declines in the dopamine transporter, a marker of dopaminergic neuron integrity. |
2001-08-16 |
2023-08-12 |
monkey |
| E C Clark, L R Baxter, L S Dure, R F Ackermann, G F Kemp, S E Bachu. Mammal-like striatal functions in Anolis. II. Distribution of dopamine D(1) and D(2) receptors, and a laminar pattern of basal ganglia sub-systems. Brain, behavior and evolution. vol 56. issue 5. 2001-07-05. PMID:11251317. |
distribution of dopamine d(1) and d(2) receptors, and a laminar pattern of basal ganglia sub-systems. |
2001-07-05 |
2023-08-12 |
Not clear |
| M J Hurley, D C Mash, P Jenne. Dopamine D(1) receptor expression in human basal ganglia and changes in Parkinson's disease. Brain research. Molecular brain research. vol 87. issue 2. 2001-06-28. PMID:11245931. |
dopamine d(1) receptor expression in human basal ganglia and changes in parkinson's disease. |
2001-06-28 |
2023-08-12 |
human |
| M I López-Ibor Alcocer, T Ortiz Alonso, M Encinas Mejías, A Fernández, F Maestú, J J López-Ibor Aliñ. [New advances in neuroimaging in the diagnosis of obsessive-compulsive disorder]. Actas espanolas de psiquiatria. vol 28. issue 5. 2001-06-07. PMID:11269909. |
given the basal ganglia receive such rich innervation from both 5-th and dopamine neurones, it has been postulated that ocd is subserved by a neuronal dysfunction in the basal ganglia and orbitofrontal cortex circuit. |
2001-06-07 |
2023-08-12 |
human |
| I Silki. The cortico-basal ganglia-thalamocortical circuit with synaptic plasticity. II. Mechanism of synergistic modulation of thalamic activity via the direct and indirect pathways through the basal ganglia. Bio Systems. vol 59. issue 1. 2001-05-24. PMID:11226622. |
a possible mechanism underlying the modulatory role of dopamine, adenosine and acetylcholine in the modification of corticostriatal synapses, subsequent changes in signal transduction through the "direct" and "indirect" pathways in the basal ganglia and variations in thalamic and neocortical cell activity is proposed. |
2001-05-24 |
2023-08-12 |
Not clear |
| E Bezard, A R Crossman, C E Gross, J M Brotchi. Structures outside the basal ganglia may compensate for dopamine loss in the presymptomatic stages of Parkinson's disease. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 15. issue 6. 2001-05-10. PMID:11292678. |
structures outside the basal ganglia may compensate for dopamine loss in the presymptomatic stages of parkinson's disease. |
2001-05-10 |
2023-08-12 |
Not clear |
| K Tang, M J Low, D K Grandy, D M Lovinge. Dopamine-dependent synaptic plasticity in striatum during in vivo development. Proceedings of the National Academy of Sciences of the United States of America. vol 98. issue 3. 2001-04-12. PMID:11158626. |
the neurotransmitters dopamine (da) and glutamate in the striatum play key roles in movement and cognition, and they are implicated in disorders of the basal ganglia such as parkinson's disease. |
2001-04-12 |
2023-08-12 |
Not clear |
| T Boraud, E Bezard, B Bioulac, C E Gros. Dopamine agonist-induced dyskinesias are correlated to both firing pattern and frequency alterations of pallidal neurones in the MPTP-treated monkey. Brain : a journal of neurology. vol 124. issue Pt 3. 2001-04-05. PMID:11222455. |
in this study, electrophysiological single-unit recordings of the neuronal activity of the globus pallidus internalis (gpi), the main basal ganglia output structure, and the globus pallidus externalis (gpe) were recorded continuously in both normal and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine treated subhuman primates before and after the administration of three dopamine agonists--apomorphine (a dopaminergic mixed agonist), skf-38393 (a d1 partial agonist) and piribedil (a d2/d3 agonist)--at doses known to induce dyskinesias in the parkinsonian monkey. |
2001-04-05 |
2023-08-12 |
monkey |
| b' J C Corvol, J M Studler, J S Schonn, J A Girault, D Herv\\xc3\\xa. Galpha(olf) is necessary for coupling D1 and A2a receptors to adenylyl cyclase in the striatum. Journal of neurochemistry. vol 76. issue 5. 2001-04-05. PMID:11238742.' |
together, these results identify galpha(olf) as a critical parameter in the responses to dopamine and adenosine in the basal ganglia. |
2001-04-05 |
2023-08-12 |
mouse |
| G Glavan, R Zorec, K Babic, D Sket, M Zivi. Dopaminergic regulation of synaptotagmin I and IV mRNAs in hemiparkinsonian rats. Neuroreport. vol 11. issue 18. 2001-03-29. PMID:11192626. |
we conclude that chronic lack of dopamine and treatment with dopamine d1 receptor agonists alter the synaptic plasticity in dopamine depleted basal ganglia. |
2001-03-29 |
2023-08-12 |
rat |
| M Yamaya, M Yanai, T Ohrui, H Arai, H Sasak. Interventions to prevent pneumonia among older adults. Journal of the American Geriatrics Society. vol 49. issue 1. 2001-03-22. PMID:11207848. |
similarly, since the production of substance p is regulated by dopaminergic neurons in the cerebral basal ganglia, treatment with dopamine analogs or potentiating drugs such as amantadine (and, of course, prevention of cerebral vascular disease, which can result in basal ganglia strokes) should affect the incidence of pneumonia. |
2001-03-22 |
2023-08-12 |
Not clear |
| T Hayakawa, M C Chang, S I Rapoport, N M Appe. Selective dopamine receptor stimulation differentially affects [3H]arachidonic acid incorporation, a surrogate marker for phospholipase A2-mediated neurotransmitter signal transduction, in a rodent model of Parkinson's disease. The Journal of pharmacology and experimental therapeutics. vol 296. issue 3. 2001-03-15. PMID:11181943. |
the data suggest up-regulation in basal ganglia and cortical dopamine circuits mediated by phospholipase a(2) ipsilateral to the substantia nigra lesion. |
2001-03-15 |
2023-08-12 |
rat |
| T González-Hernández, P Barroso-Chinea, A Acevedo, E Salido, M Rodrígue. Colocalization of tyrosine hydroxylase and GAD65 mRNA in mesostriatal neurons. The European journal of neuroscience. vol 13. issue 1. 2001-03-01. PMID:11135004. |
contrasting with the idea that in the basal ganglia, dopamine and gaba are released from different cell populations, the results suggest a more complex dopamine/gaba interaction than previously assumed, probably including cotransmission. |
2001-03-01 |
2023-08-12 |
rat |
| R Zanardi, F Artigas, R Moresco, C Colombo, C Messa, C Gobbo, E Smeraldi, F Fazi. Increased 5-hydroxytryptamine-2 receptor binding in the frontal cortex of depressed patients responding to paroxetine treatment: a positron emission tomography scan study. Journal of clinical psychopharmacology. vol 21. issue 1. 2001-03-01. PMID:11199948. |
[18f]fluoro-ethyl-spiperone labels 5-ht2a receptors in the cortex and dopamine d2 receptors in the basal ganglia. |
2001-03-01 |
2023-08-12 |
human |
| A Kaelin-Lang, P Liniger, A Probst, T Lauterburg, J M Burgunde. Adenosine A2A receptor gene expression in the normal striatum and after 6-OH-dopamine lesion. Journal of neural transmission (Vienna, Austria : 1996). vol 107. issue 8-9. 2001-02-15. PMID:11041267. |
the maintained inhibitory function of a2a r on motor activity in spite of dopamine depletion could be partly responsible for the depression of locomotor activity observed in basal ganglia disorders such as parkinson's disease. |
2001-02-15 |
2023-08-12 |
mouse |