| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Richard Grondin, Wayne A Cass, Zhiming Zhang, John A Stanford, Don M Gash, Greg A Gerhard. Glial cell line-derived neurotrophic factor increases stimulus-evoked dopamine release and motor speed in aged rhesus monkeys. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 5. 2003-03-24. PMID:12629203. |
changes in the functional dynamics of dopamine release and regulation in the basal ganglia have been posited to contribute to age-related slowing of motor functions. |
2003-03-24 |
2023-08-12 |
monkey |
| Richard Grondin, Wayne A Cass, Zhiming Zhang, John A Stanford, Don M Gash, Greg A Gerhard. Glial cell line-derived neurotrophic factor increases stimulus-evoked dopamine release and motor speed in aged rhesus monkeys. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 5. 2003-03-24. PMID:12629203. |
the data suggest that the effects of gdnf on the release of dopamine in the basal ganglia may be responsible for the improvements in motor functions and support the hypothesis that functional changes in dopamine release may contribute to motor dysfunctions characterizing senescence. |
2003-03-24 |
2023-08-12 |
monkey |
| Analía Bortolozzi, Ricardo Duffard, Ana María Evangelista de Duffar. Asymmetrical development of the monoamine systems in 2,4-dichlorophenoxyacetic acid treated rats. Neurotoxicology. vol 24. issue 1. 2003-03-21. PMID:12564390. |
in addition, the increased 5-ht content detected in both the right and left striata observed in this study could be the answer to the behaviors observed and to the early alterations in dopamine in basal ganglia by 2,4-d in neonatal exposed rats, mediated by a serotonergic modulation on the dopaminergic system. |
2003-03-21 |
2023-08-12 |
rat |
| Jean A Saint-Cy. Frontal-striatal circuit functions: context, sequence, and consequence. Journal of the International Neuropsychological Society : JINS. vol 9. issue 1. 2003-03-21. PMID:12570364. |
parkinson's disease is considered to offer only a limited view of basal ganglia function due to partial striatal depletion of dopamine and the potential involvement of other structures and transmitters in its pathology. |
2003-03-21 |
2023-08-12 |
Not clear |
| Isabel Lastres-Becker, Rosario de Miguel, Luciano De Petrocellis, Alexandros Makriyannis, Vincenzo Di Marzo, Javier Fernández-Rui. Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's disease. Journal of neurochemistry. vol 84. issue 5. 2003-03-19. PMID:12603833. |
capsaicin exhibited a strong antihyperkinetic activity and, moreover, was able to attenuate the reductions in dopamine and gaba transmission provoked by the 3np lesion, whereas cp55,940 had also antihyperkinetic activity but was unable to cause recovery of either dopamine or gaba deficits in the basal ganglia. |
2003-03-19 |
2023-08-12 |
rat |
| Alan L Whone, Robert Y Moore, Paola P Piccini, David J Brook. Plasticity of the nigropallidal pathway in Parkinson's disease. Annals of neurology. vol 53. issue 2. 2003-02-28. PMID:12557287. |
in this (18)f-dopa positron emission tomography study, we demonstrate compensatory changes in pd in another midbrain dopamine projection to the basal ganglia, the nigropallidal projection to the internal segment of the globus pallidus (gpi). |
2003-02-28 |
2023-08-12 |
Not clear |
| Jérôme Baufreton, Maurice Garret, Alicia Rivera, Adélaïda de la Calle, François Gonon, Bernard Dufy, Bernard Bioulac, Anne Taupigno. D5 (not D1) dopamine receptors potentiate burst-firing in neurons of the subthalamic nucleus by modulating an L-type calcium conductance. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 3. 2003-02-21. PMID:12574410. |
dopamine is a crucial factor in basal ganglia functioning. |
2003-02-21 |
2023-08-12 |
mouse |
| Jérôme Baufreton, Maurice Garret, Alicia Rivera, Adélaïda de la Calle, François Gonon, Bernard Dufy, Bernard Bioulac, Anne Taupigno. D5 (not D1) dopamine receptors potentiate burst-firing in neurons of the subthalamic nucleus by modulating an L-type calcium conductance. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 3. 2003-02-21. PMID:12574410. |
in current models of basal ganglia, dopamine is postulated to act on striatal neurons. |
2003-02-21 |
2023-08-12 |
mouse |
| Daphna Joel, Yael Niv, Eytan Ruppi. Actor-critic models of the basal ganglia: new anatomical and computational perspectives. Neural networks : the official journal of the International Neural Network Society. vol 15. issue 4-6. 2003-02-11. PMID:12371510. |
prominent in these are actor-critic models of basal ganglia functioning, which build on the strong resemblance between dopamine neuron activity and the temporal difference prediction error signal in the critic, and between dopamine-dependent long-term synaptic plasticity in the striatum and learning guided by a prediction error signal in the actor. |
2003-02-11 |
2023-08-12 |
Not clear |
| Daphna Joel, Yael Niv, Eytan Ruppi. Actor-critic models of the basal ganglia: new anatomical and computational perspectives. Neural networks : the official journal of the International Neural Network Society. vol 15. issue 4-6. 2003-02-11. PMID:12371510. |
we selectively review several actor-critic models of the basal ganglia with an emphasis on two important aspects: the way in which models of the critic reproduce the temporal dynamics of dopamine firing, and the extent to which models of the actor take into account known basal ganglia anatomy and physiology. |
2003-02-11 |
2023-08-12 |
Not clear |
| Navin Maswood, Richard Grondin, Zhiming Zhang, John A Stanford, Stewart P Surgener, Don M Gash, Greg A Gerhard. Effects of chronic intraputamenal infusion of glial cell line-derived neurotrophic factor (GDNF) in aged Rhesus monkeys. Neurobiology of aging. vol 23. issue 5. 2003-01-10. PMID:12392792. |
after 8 weeks of drug administration, the animals were euthanized and tissue punches were taken from the basal ganglia for measures of dopamine (da) and da metabolite levels. |
2003-01-10 |
2023-08-12 |
monkey |
| N Pavón-Fuentes, R Macías-González, L Blanco-Lezcano, L Alvarez-González, L Martínez-Martí, L Castillo-Díaz, K De La Cuétara Bernal, C Díaz, L Lorigados-Pedre, Y Coro, A Y García-Varona, J C Rosillo, E Día. [Effects of simultaneous transplant of foetal mesencephalic cells in the striatum and the subthalamic nucleus of hemiparkinsonian rats]. Revista de neurologia. vol 34. issue 10. 2002-11-12. PMID:12134319. |
a series of data from pharmacological and physiological studies offer strong evidence that the dopamine released in these nuclei may play an important role in regulating the output nuclei of the basal ganglia. |
2002-11-12 |
2023-08-12 |
rat |
| J J Canales, C Capper-Loup, D Hu, E S Choe, U Upadhyay, A M Graybie. Shifts in striatal responsivity evoked by chronic stimulation of dopamine and glutamate systems. Brain : a journal of neurology. vol 125. issue Pt 10. 2002-10-29. PMID:12244091. |
to examine functional convergence of dopamine and glutamate neurotransmitter systems in the basal ganglia, we evaluated the long-term effects of chronic stimulation of each of these systems on striatal responses to stimulation of the other. |
2002-10-29 |
2023-08-12 |
rat |
| J J Canales, C Capper-Loup, D Hu, E S Choe, U Upadhyay, A M Graybie. Shifts in striatal responsivity evoked by chronic stimulation of dopamine and glutamate systems. Brain : a journal of neurology. vol 125. issue Pt 10. 2002-10-29. PMID:12244091. |
the model provides a framework for analysing the neurological alterations associated with disorders of the basal ganglia and their treatment with pharmacotherapies affecting dopamine and glutamate neurotransmitter systems. |
2002-10-29 |
2023-08-12 |
rat |
| Glen R Hanson, Lloyd Bush, Kristen A Keefe, Mario E Alburge. Distinct responses of basal ganglia substance P systems to low and high doses of methamphetamine. Journal of neurochemistry. vol 82. issue 5. 2002-10-18. PMID:12358764. |
this study demonstrated opposite responses of the basal ganglia sp system to low and high doses of methamphetamine and suggested that a combination of dopamine d1 and d2 receptor activity contributed to these effects. |
2002-10-18 |
2023-08-12 |
Not clear |
| L A Macki. Understanding Parkinson's disease: detection and early disease management. Lippincott's primary care practice. vol 4. issue 6. 2002-10-08. PMID:11933373. |
parkinson's disease (pd) is a common, debilitating, neurodegenerative disorder characterized by neuronal loss within the basal ganglia and insufficient levels of the neurotransmitter dopamine. |
2002-10-08 |
2023-08-12 |
Not clear |
| David N Ruskin, Debra A Bergstrom, Judith R Walter. Nigrostriatal lesion and dopamine agonists affect firing patterns of rodent entopeduncular nucleus neurons. Journal of neurophysiology. vol 88. issue 1. 2002-09-06. PMID:12091570. |
the results support the view that dysfunction in the basal ganglia after midbrain dopamine neuron loss relates more consistently to abnormal activity patterns than to net changes in firing rate in the basal ganglia output nuclei, while overall decreases in firing rate in these structures may play a more important role in adverse motor reactions to dopamine agonist treatments. |
2002-09-06 |
2023-08-12 |
rat |
| Jane E Magnusson, Roxanne V Marti. Additional evidence for the involvement of the basal ganglia in formalin-induced nociception: the role of the nucleus accumbens. Brain research. vol 942. issue 1-2. 2002-09-04. PMID:12031862. |
these results implicate the nucleus accumbens in the processing of pain and provide additional evidence for the involvement of the basal ganglia and possibly dopamine in pain. |
2002-09-04 |
2023-08-12 |
Not clear |
| I G Sil'ki. A possible mechanism for the dopamine-evoked synergistic disinhibition of thalamic neurons via the "direct" and "indirect" pathways in the basal ganglia. Neuroscience and behavioral physiology. vol 32. issue 3. 2002-08-19. PMID:12135331. |
the mechanism of synaptic plasticity which we have previously proposed for striatal spiny neurons, along with published data on the predominance of dopamine-sensitive d1/d2 receptors on strionigral/striopallidal neurons, was used as the basis to propose the hypothesis that the induction of long-term potentiation/depression of the efficiency of the cortical inputs to these cells may result from the excitatory/inhibitory actions of dopamine on the activity of the neurons originating the "direct" and "indirect" pathways through the basal ganglia. |
2002-08-19 |
2023-08-12 |
Not clear |
| David Williams, Marina Tijssen, Gerard Van Bruggen, Andries Bosch, Angelo Insola, Vincenzo Di Lazzaro, Paolo Mazzone, Antonio Oliviero, Angelo Quartarone, Hans Speelman, Peter Brow. Dopamine-dependent changes in the functional connectivity between basal ganglia and cerebral cortex in humans. Brain : a journal of neurology. vol 125. issue Pt 7. 2002-08-15. PMID:12077005. |
we test the hypothesis that interaction between the human basal ganglia and cerebral cortex involves activity in multiple functional circuits characterized by their frequency of oscillation, phase characteristics, dopamine dependency and topography. |
2002-08-15 |
2023-08-12 |
human |