Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Benjamin Gauter, Roman Rukwied, Christoph Konra. Cannabinoid agonists in the treatment of blepharospasm--a case report study. Neuro endocrinology letters. vol 25. issue 1-2. 2004-08-03. PMID:15159681. |
it has been suggested that blepharospasm is neurobiologically based on a dysfunction of the basal ganglia and an impairment of the dopamine neurotransmitter system. |
2004-08-03 |
2023-08-12 |
Not clear |
M Jenuwein, C Scheller, E Neuen-Jacob, S Sopper, T Tatschner, V ter Meulen, P Riederer, E Koutsilier. Dopamine deficits and regulation of the cAMP second messenger system in brains of simian immunodeficiency virus-infected rhesus monkeys. Journal of neurovirology. vol 10. issue 3. 2004-08-02. PMID:15204921. |
the basal ganglia, structures rich in the neurotransmitter dopamine, are primarily affected during human immunodeficiency virus (hiv) infection. |
2004-08-02 |
2023-08-12 |
human |
Troels W Kjaer, Camilla Bertelsen, Paola Piccini, David Brooks, Jørgen Alving, Hans C Lo. Increased dopamine tone during meditation-induced change of consciousness. Brain research. Cognitive brain research. vol 13. issue 2. 2004-07-22. PMID:11958969. |
the tracer competes with endogenous dopamine for access to dopamine d2 receptors predominantly found in the basal ganglia. |
2004-07-22 |
2023-08-12 |
human |
J Srinivasan, Werner J Schmid. Behavioral and neurochemical effects of noradrenergic depletions with N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine in 6-hydroxydopamine-induced rat model of Parkinson's disease. Behavioural brain research. vol 151. issue 1-2. 2004-07-19. PMID:15084435. |
6-ohda lesion depleted dopamine and its metabolites dopac, hva and 3-mt in the regions of basal ganglia and it was potentiated by additional locus coeruleus denervation. |
2004-07-19 |
2023-08-12 |
rat |
Tibor Wenger, Szuzsanna Fürs. [Role of endogenous cannabinoids in cerebral reward mechanisms]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. vol 6. issue 1. 2004-06-22. PMID:15125311. |
dopamine) within the basal ganglia. |
2004-06-22 |
2023-08-12 |
Not clear |
André Nieoullon, Antoine Coquere. Dopamine: a key regulator to adapt action, emotion, motivation and cognition. Current opinion in neurology. vol 16 Suppl 2. 2004-06-03. PMID:15129844. |
more generally, the contribution of dopamine will be to increase the processing of cortical information through basal ganglia, either during the course of evolution or development. |
2004-06-03 |
2023-08-12 |
rat |
Brian R Hoover, John F Marshal. Molecular, chemical, and anatomical characterization of globus pallidus dopamine D2 receptor mRNA-containing neurons. Synapse (New York, N.Y.). vol 52. issue 2. 2004-05-21. PMID:15034916. |
gp neurons of the rodent contain either the calcium-binding protein parvalbumin (pv) or preproenkephalin (ppe) mrna, differentially innervate several basal ganglia structures, and have distinct immediate early gene responses to dopamine agonists or antagonists. |
2004-05-21 |
2023-08-12 |
Not clear |
K Y Tseng, L A Riquelme, M G Mure. Impact of D1-class dopamine receptor on striatal processing of cortical input in experimental parkinsonism in vivo. Neuroscience. vol 123. issue 2. 2004-05-12. PMID:14698740. |
recent in vivo electrophysiological studies suggest that chronic dopamine depletion alters profoundly the firing pattern of basal ganglia neurons. |
2004-05-12 |
2023-08-12 |
Not clear |
Ranjita Betarbet, Olga Poisik, Todd B Sherer, J Timothy Greenamyr. Differential expression and ser897 phosphorylation of striatal N-methyl-d-aspartate receptor subunit NR1 in animal models of Parkinson's disease. Experimental neurology. vol 187. issue 1. 2004-05-10. PMID:15081590. |
parkinson's disease (pd) is associated with complex compensatory changes in the functional and neurochemical anatomy of the basal ganglia resulting from striatal dopamine deficiency. |
2004-05-10 |
2023-08-12 |
rat |
Keun-Ah Cheon, Young-Hoon Ryu, Kee Namkoong, Chan-Hyung Kim, Jae-Jin Kim, Jong Doo Le. Dopamine transporter density of the basal ganglia assessed with [123I]IPT SPECT in drug-naive children with Tourette's disorder. Psychiatry research. vol 130. issue 1. 2004-05-04. PMID:14972371. |
dopamine transporter density of the basal ganglia assessed with [123i]ipt spect in drug-naive children with tourette's disorder. |
2004-05-04 |
2023-08-12 |
Not clear |
J Srinivasan, W J Schmid. Functional recovery of locus coeruleus noradrenergic neurons after DSP-4 lesion: effects on dopamine levels and neuroleptic induced-parkinsonian symptoms in rats. Journal of neural transmission (Vienna, Austria : 1996). vol 111. issue 1. 2004-04-30. PMID:14714212. |
here the question is addressed, whether locus coeruleus lesion with dsp-4 in rats alters dopamine concentration of the basal ganglia and influences parkinsonian behavior in a long term (6 months). |
2004-04-30 |
2023-08-12 |
rat |
Shawn Hayley, Stephen J Crocker, Patrice D Smith, Tanaya Shree, Vernice Jackson-Lewis, Serge Przedborski, Matthew Mount, Ruth Slack, Hymie Anisman, David S Par. Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 8. 2004-04-30. PMID:14985447. |
despite the reduced terminals, dopamine levels were not further suppressed by mptp treatment in mutant mice, raising the possibility of a compensatory response in basal ganglia function in fas-deficient mice. |
2004-04-30 |
2023-08-12 |
mouse |
Vicky Marshall, Donald Grosse. Role of dopamine transporter imaging in routine clinical practice. Movement disorders : official journal of the Movement Disorder Society. vol 18. issue 12. 2004-04-28. PMID:14673877. |
dopamine loss is seen even in the earliest clinical presentations of true parkinsonism; a normal scan suggests an alternative diagnosis such as essential tremor, vascular parkinsonism (unless there is focal basal ganglia infarction), drug-induced parkinsonism, or psychogenic parkinsonism. |
2004-04-28 |
2023-08-12 |
Not clear |
Fabio Blandini, Roberto Fancellu, Francesco Orzi, Giuseppe Conti, Rosaria Greco, Cristina Tassorelli, Giuseppe Napp. Selective stimulation of striatal dopamine receptors of the D1- or D2-class causes opposite changes of fos expression in the rat cerebral cortex. The European journal of neuroscience. vol 17. issue 4. 2004-04-21. PMID:12603266. |
it has been suggested that activation of striatal neurons expressing d1 or d2 dopamine receptors elicits opposite changes in the net output of the basal ganglia circuitry and, consequently, in the functional interactions of the circuit with the cerebral cortex. |
2004-04-21 |
2023-08-12 |
rat |
Fabio Blandini, Roberto Fancellu, Francesco Orzi, Giuseppe Conti, Rosaria Greco, Cristina Tassorelli, Giuseppe Napp. Selective stimulation of striatal dopamine receptors of the D1- or D2-class causes opposite changes of fos expression in the rat cerebral cortex. The European journal of neuroscience. vol 17. issue 4. 2004-04-21. PMID:12603266. |
fos was not detected in any of the other basal ganglia nuclei, regardless of the dopamine agonists or antagonists used. |
2004-04-21 |
2023-08-12 |
rat |
Fabio Blandini, Roberto Fancellu, Francesco Orzi, Giuseppe Conti, Rosaria Greco, Cristina Tassorelli, Giuseppe Napp. Selective stimulation of striatal dopamine receptors of the D1- or D2-class causes opposite changes of fos expression in the rat cerebral cortex. The European journal of neuroscience. vol 17. issue 4. 2004-04-21. PMID:12603266. |
our results confirm that striatal d1 dopamine receptors play a central role in the modulation of cortical activity, thus providing additional information on the functional interaction between basal ganglia circuitry and cerebral cortex. |
2004-04-21 |
2023-08-12 |
rat |
Yoshiko Nomura, Hideki Fukuda, Yasuo Terao, Okihide Hikosaka, Masaya Segaw. Abnormalities of voluntary saccades in Gilles de la Tourette's syndrome: pathophysiological consideration. Brain & development. vol 25 Suppl 1. 2004-04-15. PMID:14980373. |
in reference to abnormal saccades in other basal ganglia disorders with dopamine deficiency and to animal experiments with mptp monkeys, these findings postulate primary hypodopaminergic state followed by upward regulation of dopamine receptors later in ts. |
2004-04-15 |
2023-08-12 |
monkey |
L W Chen, K K L Yung, Y S Cha. Neurokinin peptides and neurokinin receptors as potential therapeutic intervention targets of basal ganglia in the prevention and treatment of Parkinson's disease. Current drug targets. vol 5. issue 2. 2004-04-13. PMID:15011953. |
nks and nk receptors, therefore, might be important molecules that are associated with functions and survival of neurons in the basal ganglia, in particular the dopamine neurons. |
2004-04-13 |
2023-08-12 |
mouse |
Reiko Kawagoe, Yoriko Takikawa, Okihide Hikosak. Reward-predicting activity of dopamine and caudate neurons--a possible mechanism of motivational control of saccadic eye movement. Journal of neurophysiology. vol 91. issue 2. 2004-03-31. PMID:14523067. |
to study how motivational signals modulate motor signals in the basal ganglia, we examined activity of midbrain dopamine (da) neurons and caudate (cd) projection neurons while monkeys were performing a one-direction-rewarded version (1dr) of memory-guided saccade task. |
2004-03-31 |
2023-08-12 |
monkey |
Michael P Hill, Erwan Bezard, Steven G McGuire, Alan R Crossman, Jonathan M Brotchie, Ann Michel, Renee Grimée, Henrik Klitgaar. Novel antiepileptic drug levetiracetam decreases dyskinesia elicited by L-dopa and ropinirole in the MPTP-lesioned marmoset. Movement disorders : official journal of the Movement Disorder Society. vol 18. issue 11. 2004-03-25. PMID:14639671. |
thus, new nondopaminergic treatment strategies targeting normalization of abnormal firing patterns in basal ganglia structures may prove useful as an adjunct to reduce dyskinesia induced by dopamine replacement therapy without affecting its antiparkinsonian action. |
2004-03-25 |
2023-08-12 |
marmoset |