| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jean-Jacques Bacci, Philippe Kachidian, Lydia Kerkerian-Le Goff, Pascal Sali. Intralaminar thalamic nuclei lesions: widespread impact on dopamine denervation-mediated cellular defects in the rat basal ganglia. Journal of neuropathology and experimental neurology. vol 63. issue 1. 2004-03-10. PMID:14748558. |
altogether, these data reveal a major antagonistic influence of thalamic and dopaminergic afferents onto the basal ganglia and suggest that degeneration of thalamic neurons in parkinson disease may represent an important factor counteracting expression of the defects associated with the dopamine denervation. |
2004-03-10 |
2023-08-12 |
rat |
| J Srinivasan, Werner J Schmid. Intensification of cataleptic response in 6-hydroxydopamine-induced neurodegeneration of substantia nigra is not dependent on the degree of dopamine depletion. Synapse (New York, N.Y.). vol 51. issue 3. 2004-02-23. PMID:14666519. |
here, the question is addressed whether the rate of development of intensification of catalepsy upon repeated testing in the same context is dependent on dopamine level in the basal ganglia. |
2004-02-23 |
2023-08-12 |
human |
| J Srinivasan, Werner J Schmid. Intensification of cataleptic response in 6-hydroxydopamine-induced neurodegeneration of substantia nigra is not dependent on the degree of dopamine depletion. Synapse (New York, N.Y.). vol 51. issue 3. 2004-02-23. PMID:14666519. |
after the completion of the behavioral experiments, various regions of basal ganglia were analyzed for dopamine and its metabolites 3,4-dihydroxyphenylacetic acid, 3-methyl tyronine, and homovanillic acid. |
2004-02-23 |
2023-08-12 |
human |
| Michael J Marino, Ornella Valenti, P Jeffrey Con. Glutamate receptors and Parkinson's disease: opportunities for intervention. Drugs & aging. vol 20. issue 5. 2004-02-19. PMID:12696997. |
glutamate plays a central role in the disruption of normal basal ganglia function, and it has been hypothesised that agents acting to restore normal glutamatergic function may provide therapeutic interventions that bypass the severe motor side effects associated with current dopamine replacement strategies. |
2004-02-19 |
2023-08-12 |
Not clear |
| Mirosław Zabek, Michał Sobstyl, Henryk Koziar. [Bilateral deep brain stimulation of subthalamic nucleus STN in the surgical treatment of Parkinson's disease]. Neurologia i neurochirurgia polska. vol 37. issue 2. 2004-02-17. PMID:14558491. |
dopamine deficiency in the nigrostriatal system leads to a series of changes in the basal ganglia, resulting in an increased neuronal activity of the subthalamic nucleus (stn). |
2004-02-17 |
2023-08-12 |
monkey |
| J A Obeso, M Rodriguez-Oroz, C Marin, F Alonso, I Zamarbide, J L Lanciego, M Rodriguez-Dia. The origin of motor fluctuations in Parkinson's disease: importance of dopaminergic innervation and basal ganglia circuits. Neurology. vol 62. issue 1 Suppl 1. 2004-02-04. PMID:14718677. |
the severity of dopamine depletion and the consequent pathophysiologic changes that occur in basal ganglia circuits determine the severity of parkinsonian signs. |
2004-02-04 |
2023-08-12 |
Not clear |
| Asunción Avila, Xavier Cardona, Montserrat Martin-Baranera, Plácida Maho, Francesc Sastre, Juan Bell. Does nefazodone improve both depression and Parkinson disease? A pilot randomized trial. Journal of clinical psychopharmacology. vol 23. issue 5. 2004-01-30. PMID:14520130. |
some of the selective serotonin reuptake inhibitors (ssri)-induced motor side effects are mediated by stimulating 5-ht2 receptors in the basal ganglia, probably because serotonin inhibits the subsequent neuronal dopamine release. |
2004-01-30 |
2023-08-12 |
Not clear |
| Richard Courtemanche, Naotaka Fujii, Ann M Graybie. Synchronous, focally modulated beta-band oscillations characterize local field potential activity in the striatum of awake behaving monkeys. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 37. 2004-01-16. PMID:14684876. |
instead, they become a dominant feature of neural activity in the basal ganglia in parkinson's disease and in parkinsonian states induced by dopamine depletion in experimental animals. |
2004-01-16 |
2023-08-12 |
human |
| Yossi Gilgun-Sherki, Eldad Melamed, Raphael Mechoulam, Daniel Offe. The CB1 cannabinoid receptor agonist, HU-210, reduces levodopa-induced rotations in 6-hydroxydopamine-lesioned rats. Pharmacology & toxicology. vol 93. issue 2. 2004-01-06. PMID:12899667. |
the co-expression of cannabinoid and dopamine receptors in the basal ganglia suggests a potential role for endocannabinoids in the control of voluntary movement in parkinson's disease. |
2004-01-06 |
2023-08-12 |
rat |
| Yuen-Sum Lau, Elizabeth Petroske, Gloria E Meredith, John Q Wan. Elevated neuronal nitric oxide synthase expression in chronic haloperidol-treated rats. Neuropharmacology. vol 45. issue 7. 2003-12-29. PMID:14573391. |
long-term administration of neuroleptic drugs, such as haloperidol, in the management of psychiatric disorders may adversely cause an irreversible neurological syndrome of tardive dyskinesia, which is associated with dopamine (da(2)) receptor supersensitivity in the basal ganglia. |
2003-12-29 |
2023-08-12 |
rat |
| Belen Ferrer, Nick Asbrock, Satish Kathuria, Daniele Piomelli, Andrea Giuffrid. Effects of levodopa on endocannabinoid levels in rat basal ganglia: implications for the treatment of levodopa-induced dyskinesias. The European journal of neuroscience. vol 18. issue 6. 2003-12-05. PMID:14511339. |
in intact animals, systemic administration of levodopa increased anandamide concentrations throughout the basal ganglia via activation of dopamine d1/d2 receptors. |
2003-12-05 |
2023-08-12 |
rat |
| Hiromi Sano, Yasunobu Yasoshima, Natsuki Matsushita, Takeshi Kaneko, Kenji Kohno, Ira Pastan, Kazuto Kobayash. Conditional ablation of striatal neuronal types containing dopamine D2 receptor disturbs coordination of basal ganglia function. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 27. 2003-11-04. PMID:14534241. |
conditional ablation of striatal neuronal types containing dopamine d2 receptor disturbs coordination of basal ganglia function. |
2003-11-04 |
2023-08-12 |
mouse |
| Hiromi Sano, Yasunobu Yasoshima, Natsuki Matsushita, Takeshi Kaneko, Kenji Kohno, Ira Pastan, Kazuto Kobayash. Conditional ablation of striatal neuronal types containing dopamine D2 receptor disturbs coordination of basal ganglia function. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 27. 2003-11-04. PMID:14534241. |
dopamine (da) exerts synaptic organization of basal ganglia circuitry through a variety of neuronal populations in the striatum. |
2003-11-04 |
2023-08-12 |
mouse |
| Ph Damie. [Fluctuations]. Revue neurologique. vol 158 Spec no 1. 2003-10-30. PMID:12690667. |
a reduction in dopamine storage capacity) are clearly involved, there are also complex postsynaptic anomalies, affecting all the basal ganglia circuity. |
2003-10-30 |
2023-08-12 |
Not clear |
| Nathalie Breysse, Marianne Amalric, Pascal Sali. Metabotropic glutamate 5 receptor blockade alleviates akinesia by normalizing activity of selective basal-ganglia structures in parkinsonian rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 23. 2003-10-08. PMID:12967992. |
here, we report that rats with partial bilateral dopamine lesions exhibit akinetic deficits associated with dramatically increased neuronal metabolic activity in selective structures of the basal ganglia such as the subthalamic nucleus and the substantia nigra pars reticulata, but not in the entopeduncular nucleus. |
2003-10-08 |
2023-08-12 |
rat |
| Keun-Ah Cheon, Young Hoon Ryu, Young-Kee Kim, Kee Namkoong, Chan-Hyung Kim, Jong Doo Le. Dopamine transporter density in the basal ganglia assessed with [123I]IPT SPET in children with attention deficit hyperactivity disorder. European journal of nuclear medicine and molecular imaging. vol 30. issue 2. 2003-09-26. PMID:12552351. |
dopamine transporter density in the basal ganglia assessed with [123i]ipt spet in children with attention deficit hyperactivity disorder. |
2003-09-26 |
2023-08-12 |
Not clear |
| Keun-Ah Cheon, Young Hoon Ryu, Young-Kee Kim, Kee Namkoong, Chan-Hyung Kim, Jong Doo Le. Dopamine transporter density in the basal ganglia assessed with [123I]IPT SPET in children with attention deficit hyperactivity disorder. European journal of nuclear medicine and molecular imaging. vol 30. issue 2. 2003-09-26. PMID:12552351. |
in this study, we investigated dopamine transporter (dat) density in children with adhd using iodine-123 labelled n-(3-iodopropen-2-yl)-2beta-carbomethoxy-3beta-(4-chlorophenyl) tropane ([(123)i]ipt) single-photon emission tomography (spet) and postulated that an alteration in dat density in the basal ganglia is responsible for dopaminergic dysfunction in children with adhd. |
2003-09-26 |
2023-08-12 |
Not clear |
| M Correa, S Mingote, A Betz, A Wisniecki, J D Salamon. Substantia nigra pars reticulata GABA is involved in the regulation of operant lever pressing: pharmacological and microdialysis studies. Neuroscience. vol 119. issue 3. 2003-09-12. PMID:12809696. |
although a large number of studies have focused upon the behavioral functions of basal ganglia dopamine, much less is known about the behavioral functions of snr gaba. |
2003-09-12 |
2023-08-12 |
Not clear |
| Paul Cumming, Pedro Rosa-Neto, Hideaki Watanabe, Donald Smith, Dirk Bender, Paul B S Clarke, Albert Gjedd. Effects of acute nicotine on hemodynamics and binding of [11C]raclopride to dopamine D2,3 receptors in pig brain. NeuroImage. vol 19. issue 3. 2003-09-09. PMID:12880838. |
positive reinforcing properties of nicotine and the psychostimulants have been attributed to elevated dopamine release in the basal ganglia. |
2003-09-09 |
2023-08-12 |
Not clear |
| Ali Saffet Gonul, Mustafa Kula, Seher Sofuoglu, Ahmet Tutus, Ertugrul Ese. Tc-99 HMPAO SPECT study of regional cerebral blood flow in olanzapine-treated schizophrenic patients. European archives of psychiatry and clinical neuroscience. vol 253. issue 1. 2003-08-25. PMID:12664310. |
dopamine d(2) blocking typical antipsychotic drugs are known to change the cerebral perfusion patterns of schizophrenic patients, especially in the frontal cortex and basal ganglia. |
2003-08-25 |
2023-08-12 |
human |