| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D J Brook. Functional imaging studies on dopamine and motor control. Journal of neural transmission (Vienna, Austria : 1996). vol 108. issue 11. 2002-05-27. PMID:11768627. |
it is argued that during unrewarded familiar actions tonic dopamine release in the basal ganglia acts to focus and filter cortical output so optimising the running of motor programmes. |
2002-05-27 |
2023-08-12 |
human |
| R Mailman, X Huang, D E Nichol. Parkinson's disease and D1 dopamine receptors. Current opinion in investigational drugs (London, England : 2000). vol 2. issue 11. 2002-05-07. PMID:11763161. |
this article reviews the role of the d1-like dopamine receptors in parkinson's disease (pd), an idea supported by the location of d1 receptors in key aspects of basal ganglia circuitry. |
2002-05-07 |
2023-08-12 |
Not clear |
| Isabel Lastres-Becker, Henrik H Hansen, Fernando Berrendero, Rosario De Miguel, Alberto Pérez-Rosado, Jorge Manzanares, José A Ramos, Javier Fernández-Rui. Alleviation of motor hyperactivity and neurochemical deficits by endocannabinoid uptake inhibition in a rat model of Huntington's disease. Synapse (New York, N.Y.). vol 44. issue 1. 2002-05-03. PMID:11842443. |
analysis of gaba, dopamine, and their related enzymes, glutamic acid decarboxylase and tyrosine hydroxylase, in the basal ganglia proved marked decreases compatible with the motor hyperkinesia. |
2002-05-03 |
2023-08-12 |
mouse |
| Isabel Lastres-Becker, Henrik H Hansen, Fernando Berrendero, Rosario De Miguel, Alberto Pérez-Rosado, Jorge Manzanares, José A Ramos, Javier Fernández-Rui. Alleviation of motor hyperactivity and neurochemical deficits by endocannabinoid uptake inhibition in a rat model of Huntington's disease. Synapse (New York, N.Y.). vol 44. issue 1. 2002-05-03. PMID:11842443. |
administration of am404 also tended to induce recovery from the neurochemical deficits caused by the toxin in gaba and dopamine indices in the basal ganglia. |
2002-05-03 |
2023-08-12 |
mouse |
| Per Svenningsson, Catherine Le Moin. Dopamine D1/5 receptor stimulation induces c-fos expression in the subthalamic nucleus: possible involvement of local D5 receptors. The European journal of neuroscience. vol 15. issue 1. 2002-04-25. PMID:11860513. |
taken together, these data suggest that dopamine d1/5 receptors are more important for the action of dopamine in the so-called indirect pathway of the basal ganglia circuitry than what is recognized in current models of basal ganglia organization. |
2002-04-25 |
2023-08-12 |
rat |
| Barbara L Waszczak, Lynn P Martin, Heather E Finlay, Natalie Zahr, James R Stella. Effects of individual and concurrent stimulation of striatal D1 and D2 dopamine receptors on electrophysiological and behavioral output from rat basal ganglia. The Journal of pharmacology and experimental therapeutics. vol 300. issue 3. 2002-03-28. PMID:11861790. |
effects of individual and concurrent stimulation of striatal d1 and d2 dopamine receptors on electrophysiological and behavioral output from rat basal ganglia. |
2002-03-28 |
2023-08-12 |
rat |
| Thomas Wichmann, Michele A Kliem, Jesus Soare. Slow oscillatory discharge in the primate basal ganglia. Journal of neurophysiology. vol 87. issue 2. 2002-03-26. PMID:11826081. |
oscillations with periods in the multisecond range have previously been recorded in basal ganglia neurons of awake paralyzed rats, and in these animals were shown to be increased by systemic dopaminergic stimulation, but not altered by depletion of the nigrostriatal dopamine supply. |
2002-03-26 |
2023-08-12 |
rat |
| O Faroon, D Jones, C de Ros. Effects of polychlorinated biphenyls on the nervous system. Toxicology and industrial health. vol 16. issue 7-8. 2002-03-08. PMID:11693948. |
of all the observed changes, the most consistent has been a decrease in dopamine content in basal ganglia and prefrontal cortex, but further research is needed before specific neurobehavioral deficits can be correlated with pcb-induced changes in specific neurotransmitters in specific brain areas. |
2002-03-08 |
2023-08-12 |
mouse |
| William S Cobb, Elizabeth D Abercrombi. Distinct roles for nigral GABA and glutamate receptors in the regulation of dendritic dopamine release under normal conditions and in response to systemic haloperidol. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 4. 2002-02-26. PMID:11850467. |
the present studies used in vivo microdialysis to determine the potential roles of nigral gaba and glutamate receptors in the regulation of dendritic dopamine release under normal conditions and when dopamine signaling in the basal ganglia is compromised after systemic haloperidol administration. |
2002-02-26 |
2023-08-12 |
Not clear |
| William S Cobb, Elizabeth D Abercrombi. Distinct roles for nigral GABA and glutamate receptors in the regulation of dendritic dopamine release under normal conditions and in response to systemic haloperidol. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 4. 2002-02-26. PMID:11850467. |
circuit-level changes in the basal ganglia involving an increased glutamatergic drive to the sn appear to underlie the increase in dendritic dopamine release that occurs in response to systemic haloperidol administration. |
2002-02-26 |
2023-08-12 |
Not clear |
| D K Ingram, S Chefer, J Matochik, T D Moscrip, J Weed, G S Roth, E D London, M A Lan. Aging and caloric restriction in nonhuman primates: behavioral and in vivo brain imaging studies. Annals of the New York Academy of Sciences. vol 928. 2002-02-22. PMID:11795523. |
although additional longitudinal analysis is needed to confirm the present results, it would appear that locomotor activity, volume of the basal ganglia, as well as dopamine d2 receptor binding potential provide reliable, noninvasive biomarkers of aging in rhesus monkeys. |
2002-02-22 |
2023-08-12 |
monkey |
| S V Argyropoulos, C J Bell, D J Nut. Brain function in social anxiety disorder. The Psychiatric clinics of North America. vol 24. issue 4. 2002-02-20. PMID:11723629. |
the best evidence for neurotransmitter abnormality so far is for altered dopamine function at the level of the basal ganglia, either pre- or postsynaptic, which may result in reduced basal ganglia function so that the normal fluidity of social motor functions (e.g., smiling, eye movements, and speech) are impaired, thus leading to the cognitive symptoms of social anxiety and the subsequent generation of avoidance behavior. |
2002-02-20 |
2023-08-12 |
Not clear |
| I G Sil'ki. [A possible mechanism of dopamine-induced synergistic disinhibition of thalamic cells via "direct" and "indirect" pathways in basal ganglia]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 51. issue 3. 2002-02-19. PMID:11550635. |
on the basis of the mechanism of synaptic plasticity that we have earlier suggested for striatal spiny neurons and with regard to the known data about the predominance of dopamine-sensitive d1/d2 receptors on the striatonigral/striatopallidal cells it is hypothesized that the induction of the long-term potentiation/depression of the efficacy of excitatory cortical inputs to these cells can underlie the excitatory/inhibitory effect of dopamine on the activity of neurons that originate the "direct"/"indirect" pathways through the basal ganglia. |
2002-02-19 |
2023-08-12 |
Not clear |
| B L Waszczak, L Martin, N Boucher, N Zahr, R W Sikes, J R Stella. Electrophysiological and behavioral output of the rat basal ganglia after intrastriatal infusion of d-amphetamine: lack of support for the basal ganglia model. Brain research. vol 920. issue 1-2. 2002-02-07. PMID:11716823. |
these results show that (i) bilateral but not unilateral activation of striatal dopamine receptors is needed to elicit behavioral and electrophysiological output from the basal ganglia, and (ii) motor activation is apparently not signaled by a generalized inhibition of snpr firing, as is predicted by the basal ganglia model. |
2002-02-07 |
2023-08-12 |
rat |
| C Deransart, G B Landwehrmeyer, T J Feuerstein, C H Lückin. Up-regulation of D3 dopaminergic receptor mRNA in the core of the nucleus accumbens accompanies the development of seizures in a genetic model of absence-epilepsy in the rat. Brain research. Molecular brain research. vol 94. issue 1-2. 2002-01-03. PMID:11597777. |
the basal ganglia system is thought to play a key role in the control of absence-seizures and there is ample evidence that epileptic seizures modify brain dopamine function. |
2002-01-03 |
2023-08-12 |
rat |
| Z Zhang, A Andersen, R Grondin, T Barber, R Avison, G Gerhardt, D Gas. Pharmacological MRI mapping of age-associated changes in basal ganglia circuitry of awake rhesus monkeys. NeuroImage. vol 14. issue 5. 2002-01-02. PMID:11697947. |
while the pathophysiological changes induced by the loss of dopamine innervation in the basal ganglia by parkinson's disease (pd) are well studied, little is known about functional changes in the neural circuitry of this area during normal aging. |
2002-01-02 |
2023-08-12 |
monkey |
| J C Villares, J N Staval. Age-related changes in the N-methyl-D-aspartate receptor binding sites within the human basal ganglia. Experimental neurology. vol 171. issue 2. 2001-12-05. PMID:11573991. |
these results demonstrate that the basal ganglia have age-associated reductions in dopamine transporter uptake and nmda receptors. |
2001-12-05 |
2023-08-12 |
human |
| J C Villares, J N Staval. Age-related changes in the N-methyl-D-aspartate receptor binding sites within the human basal ganglia. Experimental neurology. vol 171. issue 2. 2001-12-05. PMID:11573991. |
the dopamine transporter uptake and nmda receptors appear to be vulnerable to the aging process in the basal ganglia. |
2001-12-05 |
2023-08-12 |
human |
| G Conti, F Blandini, C Tassorelli, F Giubilei, F Fornai, A Zocchi, F Orz. Intrastriatal injection of D1 or D2 dopamine agonists affects glucose utilization in both the direct and indirect pathways of the rat basal ganglia. Neuroscience letters. vol 309. issue 3. 2001-12-04. PMID:11514066. |
intrastriatal injection of d1 or d2 dopamine agonists affects glucose utilization in both the direct and indirect pathways of the rat basal ganglia. |
2001-12-04 |
2023-08-12 |
rat |
| G Conti, F Blandini, C Tassorelli, F Giubilei, F Fornai, A Zocchi, F Orz. Intrastriatal injection of D1 or D2 dopamine agonists affects glucose utilization in both the direct and indirect pathways of the rat basal ganglia. Neuroscience letters. vol 309. issue 3. 2001-12-04. PMID:11514066. |
two distinct pathways are thought to connect the striatum to the basal ganglia output nuclei: a direct pathway, originating from neurons bearing dopamine, d(1) receptors and an indirect pathway, originating from neurons expressing d(2) receptors. |
2001-12-04 |
2023-08-12 |
rat |