| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zia Rahman, Johannes Schwarz, Stephen J Gold, Venetia Zachariou, Marc N Wein, Kwang Ho Choi, Abraham Kovoor, Ching Kang Chen, Ralph J DiLeone, Sigrid C Schwarz, Dana E Selley, Laura J Sim-Selley, Michel Barrot, Robert R Luedtke, David Self, Rachael L Neve, Henry A Lester, Melvin I Simon, Eric J Nestle. RGS9 modulates dopamine signaling in the basal ganglia. Neuron. vol 38. issue 6. 2003-08-15. PMID:12818179. |
rgs9 modulates dopamine signaling in the basal ganglia. |
2003-08-15 |
2023-08-12 |
mouse |
| M D Julian, A B Martin, B Cuellar, F Rodriguez De Fonseca, M Navarro, R Moratalla, L M Garcia-Segur. Neuroanatomical relationship between type 1 cannabinoid receptors and dopaminergic systems in the rat basal ganglia. Neuroscience. vol 119. issue 1. 2003-07-28. PMID:12763090. |
dopamine and endocannabinoids are neurotransmitters known to play a role in the activity of the basal ganglia motor circuit. |
2003-07-28 |
2023-08-12 |
rat |
| Barbara Cacciari, Giorgia Pastorin, Giampiero Spallut. Medicinal chemistry of A2A adenosine receptor antagonists. Current topics in medicinal chemistry. vol 3. issue 4. 2003-07-11. PMID:12570758. |
due to the clearly demonstrated receptor-receptor interaction between adenosine a(2a) and dopamine d(2) receptors in the basal ganglia, the discovery and development of potent and selective a(2a)adenosine receptor antagonists became, in the last ten years, an attractive field of research to discovery new drugs for the treatment of neurodegenerative disorders, such as parkinsons disease. |
2003-07-11 |
2023-08-12 |
Not clear |
| A Tofighy, A Abbott, D Centonze, A J Cooper, E Noor, S M Pearce, M Puntis, I M Stanford, M A Wigmore, M G Lace. Excitation by dopamine of rat subthalamic nucleus neurones in vitro-a direct action with unconventional pharmacology. Neuroscience. vol 116. issue 1. 2003-06-24. PMID:12535949. |
this nucleus has a pivotal role in basal ganglia function and voluntary movement control and the possibility that dopamine, and dopaminergic medication used in parkinson's disease, might directly influence its activity is of considerable interest. |
2003-06-24 |
2023-08-12 |
rat |
| Lauren M Billings, John F Marshal. D2 antagonist-induced c-fos in an identified subpopulation of globus pallidus neurons by a direct intrapallidal action. Brain research. vol 964. issue 2. 2003-06-18. PMID:12576184. |
much research now supports the view that the dopaminergic innervation of the globus pallidus external segment (gp) influences basal ganglia information processing via pallidal dopamine (da) d2, d3, and possibly d1 receptors. |
2003-06-18 |
2023-08-12 |
rat |
| Krystyna Ossowsk. Neuronal basis of neuroleptic-induced extrapyramidal side effects. Polish journal of pharmacology. vol 54. issue 4. 2003-06-03. PMID:12523484. |
primary and secondary changes in the function of dopamine receptors lead to partially opposite, pathological changes in the activity of neuronal pathways connecting the basal ganglia. |
2003-06-03 |
2023-08-12 |
Not clear |
| Wilhelmus J A J Smeets, Jesus M Lopez, Agustín Gonzále. Immunohistochemical localization of DARPP-32 in the brain of the turtle, Pseudemys scripta elegans: further assessment of its relationship with dopaminergic systems in reptiles. Journal of chemical neuroanatomy. vol 25. issue 2. 2003-05-30. PMID:12663057. |
a previous study in the lizard gekko gecko has revealed that the distribution of darpp-32 (a phosphoprotein related to the dopamine d(1)-receptor) largely resembles the pattern observed in birds and mammals, at least as far as basal ganglia structures are concerned. |
2003-05-30 |
2023-08-12 |
Not clear |
| N D Volkow, J S Fowler, G Wang, Y Ding, S J Gatle. Mechanism of action of methylphenidate: insights from PET imaging studies. Journal of attention disorders. vol 6 Suppl 1. 2003-05-22. PMID:12685517. |
we have also shown that therapeutic doses of mph significantly enhance extracellular dopamine (da) in the basal ganglia, which is an effect that appears to be modulated by the rate of da release and that is affected by age (older subjects show less effect). |
2003-05-22 |
2023-08-12 |
human |
| D N Ruskin, D A Bergstrom, P L Tierney, J R Walter. Correlated multisecond oscillations in firing rate in the basal ganglia: modulation by dopamine and the subthalamic nucleus. Neuroscience. vol 117. issue 2. 2003-05-21. PMID:12614683. |
correlated multisecond oscillations in firing rate in the basal ganglia: modulation by dopamine and the subthalamic nucleus. |
2003-05-21 |
2023-08-12 |
rat |
| R A Rendon, L Shuster, N H Dodma. The effect of the NMDA receptor blocker, dextromethorphan, on cribbing in horses. Pharmacology, biochemistry, and behavior. vol 68. issue 1. 2003-05-20. PMID:11274707. |
dopamine in turn activates basal ganglia motor programs, reinforcing behavior via a reward mechanism. |
2003-05-20 |
2023-08-12 |
Not clear |
| Peter Jenne. The contribution of the MPTP-treated primate model to the development of new treatment strategies for Parkinson's disease. Parkinsonism & related disorders. vol 9. issue 3. 2003-04-29. PMID:12573867. |
there is now accumulating evidence that the pulsatile manner in which short-acting agents stimulate striatal dopamine receptors is a key contributing factor to the priming of the basal ganglia for dyskinesia induction. |
2003-04-29 |
2023-08-12 |
Not clear |
| Amanpreet Singh, S K Kulkarn. Role of adenosine in drug-induced catatonia in mice. Indian journal of experimental biology. vol 40. issue 8. 2003-04-10. PMID:12597016. |
apart from dopamine, acetylcholine and glutamate, adenosinc has also been identified in the basal ganglia. |
2003-04-10 |
2023-08-12 |
mouse |
| François Cassim, Etienne Labyt, David Devos, Luc Defebvre, Alain Destée, Philippe Derambur. Relationship between oscillations in the basal ganglia and synchronization of cortical activity. Epileptic disorders : international epilepsy journal with videotape. vol 4 Suppl 3. 2003-04-09. PMID:12495873. |
dopamine depletion results in a global increase of oscillations within the whole basal ganglia system, particularly in the gp-nst network. |
2003-04-09 |
2023-08-12 |
human |
| Alicia Rivera, Israel Alberti, Ana B Martín, José A Narváez, Adelaida de la Calle, Rosario Moratall. Molecular phenotype of rat striatal neurons expressing the dopamine D5 receptor subtype. The European journal of neuroscience. vol 16. issue 11. 2003-03-25. PMID:12473072. |
dopamine is one of the principal neurotransmitters in the basal ganglia, where it plays a critical role in motor control and cognitive function through its interactions with the specific dopamine receptors d1 to d5. |
2003-03-25 |
2023-08-12 |
rat |
| Richard Grondin, Wayne A Cass, Zhiming Zhang, John A Stanford, Don M Gash, Greg A Gerhard. Glial cell line-derived neurotrophic factor increases stimulus-evoked dopamine release and motor speed in aged rhesus monkeys. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 5. 2003-03-24. PMID:12629203. |
changes in the functional dynamics of dopamine release and regulation in the basal ganglia have been posited to contribute to age-related slowing of motor functions. |
2003-03-24 |
2023-08-12 |
monkey |
| Richard Grondin, Wayne A Cass, Zhiming Zhang, John A Stanford, Don M Gash, Greg A Gerhard. Glial cell line-derived neurotrophic factor increases stimulus-evoked dopamine release and motor speed in aged rhesus monkeys. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 5. 2003-03-24. PMID:12629203. |
the data suggest that the effects of gdnf on the release of dopamine in the basal ganglia may be responsible for the improvements in motor functions and support the hypothesis that functional changes in dopamine release may contribute to motor dysfunctions characterizing senescence. |
2003-03-24 |
2023-08-12 |
monkey |
| Analía Bortolozzi, Ricardo Duffard, Ana María Evangelista de Duffar. Asymmetrical development of the monoamine systems in 2,4-dichlorophenoxyacetic acid treated rats. Neurotoxicology. vol 24. issue 1. 2003-03-21. PMID:12564390. |
in addition, the increased 5-ht content detected in both the right and left striata observed in this study could be the answer to the behaviors observed and to the early alterations in dopamine in basal ganglia by 2,4-d in neonatal exposed rats, mediated by a serotonergic modulation on the dopaminergic system. |
2003-03-21 |
2023-08-12 |
rat |
| Jean A Saint-Cy. Frontal-striatal circuit functions: context, sequence, and consequence. Journal of the International Neuropsychological Society : JINS. vol 9. issue 1. 2003-03-21. PMID:12570364. |
parkinson's disease is considered to offer only a limited view of basal ganglia function due to partial striatal depletion of dopamine and the potential involvement of other structures and transmitters in its pathology. |
2003-03-21 |
2023-08-12 |
Not clear |
| Isabel Lastres-Becker, Rosario de Miguel, Luciano De Petrocellis, Alexandros Makriyannis, Vincenzo Di Marzo, Javier Fernández-Rui. Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's disease. Journal of neurochemistry. vol 84. issue 5. 2003-03-19. PMID:12603833. |
capsaicin exhibited a strong antihyperkinetic activity and, moreover, was able to attenuate the reductions in dopamine and gaba transmission provoked by the 3np lesion, whereas cp55,940 had also antihyperkinetic activity but was unable to cause recovery of either dopamine or gaba deficits in the basal ganglia. |
2003-03-19 |
2023-08-12 |
rat |
| Alan L Whone, Robert Y Moore, Paola P Piccini, David J Brook. Plasticity of the nigropallidal pathway in Parkinson's disease. Annals of neurology. vol 53. issue 2. 2003-02-28. PMID:12557287. |
in this (18)f-dopa positron emission tomography study, we demonstrate compensatory changes in pd in another midbrain dopamine projection to the basal ganglia, the nigropallidal projection to the internal segment of the globus pallidus (gpi). |
2003-02-28 |
2023-08-12 |
Not clear |