| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L M Ambrose, E M Unterwald, E J Van Bockstael. Ultrastructural evidence for co-localization of dopamine D2 and micro-opioid receptors in the rat dorsolateral striatum. The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology. vol 279. issue 1. 2004-11-24. PMID:15224400. |
previous studies have shown significant changes in dopamine and opioid receptors in the basal ganglia following administration of cocaine. |
2004-11-24 |
2023-08-12 |
rat |
| Janice W Kansy, S Colette Daubner, Akinori Nishi, Naoki Sotogaku, Michael D Lloyd, Chan Nguyen, Lin Lu, John W Haycock, Bruce T Hope, Paul F Fitzpatrick, James A Bib. Identification of tyrosine hydroxylase as a physiological substrate for Cdk5. Journal of neurochemistry. vol 91. issue 2. 2004-11-15. PMID:15447670. |
within the reward/motor circuitry of the basal ganglia, cdk5 regulates dopamine neurotransmission via phosphorylation of the postsynaptic signal transduction pathway integrator, darpp-32 (dopamine- and cyclic amp-regulated phosphoprotein, m(r) 32,000). |
2004-11-15 |
2023-08-12 |
mouse |
| Masahiro Nomot. [The pharmacological and rational theory for the drug development of Parkinson's disease]. Nihon rinsho. Japanese journal of clinical medicine. vol 62. issue 9. 2004-11-06. PMID:15462380. |
the basal ganglia in the brain contains glutamate, dopamine, serotonin, noradrenaline, cck, adenosine, opioid, cannabinoid, etc. |
2004-11-06 |
2023-08-12 |
Not clear |
| Andrew H Evans, Andrew J Lee. Dopamine dysregulation syndrome in Parkinson's disease. Current opinion in neurology. vol 17. issue 4. 2004-11-01. PMID:15247533. |
this review examines the phenomenology of dopamine dysregulation syndrome in relation to the current understanding of basal ganglia function and its impact on long-term management. |
2004-11-01 |
2023-08-12 |
Not clear |
| J Srinivasan, Werner J Schmid. Treatment with alpha2-adrenoceptor antagonist, 2-methoxy idazoxan, protects 6-hydroxydopamine-induced Parkinsonian symptoms in rats: neurochemical and behavioral evidence. Behavioural brain research. vol 154. issue 2. 2004-11-01. PMID:15313023. |
the concentrations of dopamine, 5-hydroxytryptamine and its metabolites were analysed in the various regions of the basal ganglia. |
2004-11-01 |
2023-08-12 |
rat |
| J Srinivasan, Werner J Schmid. Treatment with alpha2-adrenoceptor antagonist, 2-methoxy idazoxan, protects 6-hydroxydopamine-induced Parkinsonian symptoms in rats: neurochemical and behavioral evidence. Behavioural brain research. vol 154. issue 2. 2004-11-01. PMID:15313023. |
the concentrations of noradrenaline and dopamine were measured in the regions innervated by locus coeruleus neurons and in the basal ganglia respectively, after 2-methoxy idazoxan treatment. |
2004-11-01 |
2023-08-12 |
rat |
| Ranjita Betarbet, J Timothy Greenamyr. Regulation of dopamine receptor and neuropeptide expression in the basal ganglia of monkeys treated with MPTP. Experimental neurology. vol 189. issue 2. 2004-10-28. PMID:15380489. |
in parkinson's disease (pd), striatal dopamine deficiency has been associated with complex changes in the functional and neurochemical anatomy of the basal ganglia. |
2004-10-28 |
2023-08-12 |
monkey |
| Ranjita Betarbet, J Timothy Greenamyr. Regulation of dopamine receptor and neuropeptide expression in the basal ganglia of monkeys treated with MPTP. Experimental neurology. vol 189. issue 2. 2004-10-28. PMID:15380489. |
in this study, we simultaneously analyzed the regulation of d1 and d2 dopamine receptors and levels of the neuropeptides, substance p, and enkephalin (enk) in various basal ganglia nuclei following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced dopaminergic denervation of striatum in nonhuman primates. |
2004-10-28 |
2023-08-12 |
monkey |
| N A Harrison, A Church, A Nisbet, P Rudge, G Giovannon. Late recurrences of Sydenham's chorea are not associated with anti-basal ganglia antibodies. Journal of neurology, neurosurgery, and psychiatry. vol 75. issue 10. 2004-10-19. PMID:15377702. |
we suggest the likely pathophysiology to be dopamine hypersensitivity of chronically damaged basal ganglia neurones possibly following induction of an autoimmune antibody response in childhood. |
2004-10-19 |
2023-08-12 |
Not clear |
| L-W Chen, H-J Hu, H-L Liu, K K L Yung, Y S Cha. Identification of brain-derived neurotrophic factor in nestin-expressing astroglial cells in the neostriatum of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice. Neuroscience. vol 126. issue 4. 2004-10-08. PMID:15207328. |
taken together with previous observations, this study suggests that nestin-expressing activated astroglial cells, possibly partially through synthesizing and releasing neurotrophic factors such as bdnf in the basal ganglia, may play important roles in protection of nigrostriatal dopamine neurons and in the pathogenesis of parkinson's disease in mammals. |
2004-10-08 |
2023-08-12 |
mouse |
| Chan-Hyung Kim, Min-Seong Koo, Keun-Ah Cheon, Young-Hoon Ryu, Jong-Doo Lee, Hong-Shick Le. Dopamine transporter density of basal ganglia assessed with [123I]IPT SPET in obsessive-compulsive disorder. European journal of nuclear medicine and molecular imaging. vol 30. issue 12. 2004-10-05. PMID:14513291. |
dopamine transporter density of basal ganglia assessed with [123i]ipt spet in obsessive-compulsive disorder. |
2004-10-05 |
2023-08-12 |
Not clear |
| Chan-Hyung Kim, Min-Seong Koo, Keun-Ah Cheon, Young-Hoon Ryu, Jong-Doo Lee, Hong-Shick Le. Dopamine transporter density of basal ganglia assessed with [123I]IPT SPET in obsessive-compulsive disorder. European journal of nuclear medicine and molecular imaging. vol 30. issue 12. 2004-10-05. PMID:14513291. |
in the present study, we investigated the dat density of the basal ganglia using iodine-123 labelled n-(3-iodopropen-2-yl)-2beta-carbomethoxy-3beta-(4-chlorophenyl) tropane ([123i]ipt) single-photon emission tomography (spet) and evaluated the activity of the presynaptic dopamine function in patients with ocd. |
2004-10-05 |
2023-08-12 |
Not clear |
| Chan-Hyung Kim, Min-Seong Koo, Keun-Ah Cheon, Young-Hoon Ryu, Jong-Doo Lee, Hong-Shick Le. Dopamine transporter density of basal ganglia assessed with [123I]IPT SPET in obsessive-compulsive disorder. European journal of nuclear medicine and molecular imaging. vol 30. issue 12. 2004-10-05. PMID:14513291. |
we performed brain spet 2 h after the intravenous administration of [123i]ipt and carried out both quantitative and qualitative analyses using the obtained spet data, which were reconstructed for the assessment of the specific/non-specific dopamine transporter (dat) binding ratio in the basal ganglia. |
2004-10-05 |
2023-08-12 |
Not clear |
| Beth E Fisher, Giselle M Petzinger, Kerry Nixon, Elizabeth Hogg, Samuel Bremmer, Charles K Meshul, Michael W Jakowe. Exercise-induced behavioral recovery and neuroplasticity in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mouse basal ganglia. Journal of neuroscience research. vol 77. issue 3. 2004-09-09. PMID:15248294. |
the expression of proteins and genes involved in basal ganglia function including the dopamine transporter (dat), tyrosine hydroxylase (th), and the dopamine d1 and d2 receptors, as well as alterations on glutamate immunolabeling were determined. |
2004-09-09 |
2023-08-12 |
mouse |
| Genela Morris, David Arkadir, Alon Nevet, Eilon Vaadia, Hagai Bergma. Coincident but distinct messages of midbrain dopamine and striatal tonically active neurons. Neuron. vol 43. issue 1. 2004-08-26. PMID:15233923. |
since striatal dopamine and acetylcholine affect plasticity of cortico-striatal transmission and are both crucial to learning, they may serve as teachers in the basal ganglia circuits. |
2004-08-26 |
2023-08-12 |
monkey |
| Genela Morris, Alon Nevet, Hagai Bergma. Anatomical funneling, sparse connectivity and redundancy reduction in the neural networks of the basal ganglia. Journal of physiology, Paris. vol 97. issue 4-6. 2004-08-24. PMID:15242667. |
the major anatomical characteristics of the main axis of the basal ganglia are: (1) numerical reduction in the number of neurons across layers of the feed-forward network, (2) lateral inhibitory connections within the layers, and (3) neuro-modulatory effects of dopamine and acetylcholine, both on the basal ganglia neurons and on the efficacy of information transmission along the basal ganglia axis. |
2004-08-24 |
2023-08-12 |
Not clear |
| Fadwa El-Banoua, Isabel Caraballo, Juan A Flores, Beatriz Galan-Rodriguez, Emilio Fernandez-Espej. Effects on turning of microinjections into basal ganglia of D(1) and D(2) dopamine receptors agonists and the cannabinoid CB(1) antagonist SR141716A in a rat Parkinson's model. Neurobiology of disease. vol 16. issue 2. 2004-08-13. PMID:15193294. |
brain cannabinoid cb(1) receptors are expressed in neural areas that contribute to movement such as basal ganglia, where they co-localize with dopamine d(1) and d(2) receptors. |
2004-08-13 |
2023-08-12 |
rat |
| Fadwa El-Banoua, Isabel Caraballo, Juan A Flores, Beatriz Galan-Rodriguez, Emilio Fernandez-Espej. Effects on turning of microinjections into basal ganglia of D(1) and D(2) dopamine receptors agonists and the cannabinoid CB(1) antagonist SR141716A in a rat Parkinson's model. Neurobiology of disease. vol 16. issue 2. 2004-08-13. PMID:15193294. |
the objective of the present study was to further study the functional role of cb(1) receptors along with d(1) and d(2) dopamine receptors of basal ganglia by local injections of sr141716a (cb(1) receptor antagonist), skf-38393 (d(1) agonist), and quinpirole (d(2) agonist), in a rat parkinson's model. |
2004-08-13 |
2023-08-12 |
rat |
| Hans Sjøholm, Trond Bratlid, Johan Sundsfjor. 123I-beta-CIT SPECT demonstrates increased presynaptic dopamine transporter binding sites in basal ganglia in vivo in schizophrenia. Psychopharmacology. vol 173. issue 1-2. 2004-08-06. PMID:14712338. |
123i-beta-cit spect demonstrates increased presynaptic dopamine transporter binding sites in basal ganglia in vivo in schizophrenia. |
2004-08-06 |
2023-08-12 |
Not clear |
| Hans Sjøholm, Trond Bratlid, Johan Sundsfjor. 123I-beta-CIT SPECT demonstrates increased presynaptic dopamine transporter binding sites in basal ganglia in vivo in schizophrenia. Psychopharmacology. vol 173. issue 1-2. 2004-08-06. PMID:14712338. |
the dopamine hypothesis for schizophrenia postulates overactivity of dopamine transmission in the basal ganglia. |
2004-08-06 |
2023-08-12 |
Not clear |