| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fernando Cardozo-Pelaez, David P Cox, Celeste Boli. Lack of the DNA repair enzyme OGG1 sensitizes dopamine neurons to manganese toxicity during development. Gene expression. vol 12. issue 4-6. 2006-01-20. PMID:16358418. |
epidemiological studies have demonstrated that exposure to elevated levels of manganese produces neuropathological changes localized to the basal ganglia, including neuronal loss and depletions in striatal dopamine content. |
2006-01-20 |
2023-08-12 |
mouse |
| Kuei Y Tseng, Lucila Kargieman, Sebastian Gacio, Luis A Riquelme, M Gustavo Mure. Consequences of partial and severe dopaminergic lesion on basal ganglia oscillatory activity and akinesia. The European journal of neuroscience. vol 22. issue 10. 2006-01-17. PMID:16307600. |
severe chronic dopamine (da) depletion increases the proportion of neurons in the basal ganglia that fire rhythmic bursts of action potential (lfo units) synchronously with the cortical oscillations. |
2006-01-17 |
2023-08-12 |
rat |
| Liang-Wei Chen, Kin-Lam Yung, Ying-Shing Cha. Reactive astrocytes as potential manipulation targets in novel cell replacement therapy of Parkinson's disease. Current drug targets. vol 6. issue 7. 2005-12-15. PMID:16305461. |
future approaches deserve to target on neurotrophic functions of reactive astrocytes in the basal ganglia and interventions to facilitate survival and axonal regeneration of dopamine neurons or differentiation of dopamine progenitor cells. |
2005-12-15 |
2023-08-12 |
Not clear |
| Luigi Francesco Agnati, Sergi Ferre, Raffaella Burioni, Amina Woods, Susanna Genedani, Rafael Franco, Kjell Fux. Existence and theoretical aspects of homomeric and heteromeric dopamine receptor complexes and their relevance for neurological diseases. Neuromolecular medicine. vol 7. issue 1-2. 2005-12-08. PMID:16052039. |
dopamine (da) and other receptors physically interact in the plasma membrane of basal ganglia neurons forming receptor mosaics (rms). |
2005-12-08 |
2023-08-12 |
Not clear |
| Jordi Bové, Jordi Serrats, Guadalupe Mengod, Roser Cortés, Eduardo Tolosa, Concepció Mari. Neuroprotection induced by the adenosine A2A antagonist CSC in the 6-OHDA rat model of parkinsonism: effect on the activity of striatal output pathways. Experimental brain research. vol 165. issue 3. 2005-12-01. PMID:15968457. |
in parkinson's disease (pd), the striatal dopamine depletion and the following overactivation of the indirect pathway of the basal ganglia leads to very early disinhibition of the subthalamic nucleus (stn) that may contribute to the progression of pd by glutamatergic overstimulation of the dopaminergic neurons in the substantia nigra. |
2005-12-01 |
2023-08-12 |
rat |
| Yuting Tang, Keith T Demares. Distinctive and synergistic signaling of human adenosine A2a and dopamine D2L receptors in CHO cells. Journal of receptor and signal transduction research. vol 25. issue 3. 2005-11-22. PMID:16194932. |
adenosine a(2a) receptor (a(2a)r) colocalizes with dopamine d(2) receptor (d(2)r) in the basal ganglia and modulates d(2)r-mediated dopaminergic activities. |
2005-11-22 |
2023-08-12 |
mouse |
| Cécile Lavoute, Michel Weiss, Jean-Claude Rostai. Effects of repeated hyperbaric nitrogen-oxygen exposures on the striatal dopamine release and on motor disturbances in rats. Brain research. vol 1056. issue 1. 2005-11-21. PMID:16112095. |
repetitive exposures to 1 mpa of nitrogen induced a reversal effect on the dopamine release which suggests a neurochemical change at the level of the neurotransmitter regulation processes of the basal ganglia. |
2005-11-21 |
2023-08-12 |
rat |
| Holger Fuchs, Jens Nagel, Wolfgang Haube. Effects of physiological and pharmacological stimuli on dopamine release in the rat globus pallidus. Neurochemistry international. vol 47. issue 7. 2005-11-15. PMID:16122838. |
a major aspect of understanding functions of the globus pallidus (gp) within the basal ganglia is the significance of its dopamine innervation. |
2005-11-15 |
2023-08-12 |
rat |
| A N Talaenko, G K Krivobok, D V Pankrat'ev, N V Goncharenk. [Neurochemical mechanisms of dorsal pallidum in antiadverse effects of anxiolytics of different models of anxiety]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 91. issue 7. 2005-11-15. PMID:16206621. |
dopamine, apomorphine, gaba, chlordiazepoxide, phenibut and indoter injected locally into this formation of basal ganglia do not affect the mechanisms of the involuntary movement, but counteract the conditions of anxiety in both models of behaviour. |
2005-11-15 |
2023-08-12 |
rat |
| Pershia Samadi, Laurent Grégoire, Arash Rassoulpour, Paolo Guidetti, Emanuela Izzo, Robert Schwarcz, Paul J Bédar. Effect of kynurenine 3-hydroxylase inhibition on the dyskinetic and antiparkinsonian responses to levodopa in Parkinsonian monkeys. Movement disorders : official journal of the Movement Disorder Society. vol 20. issue 7. 2005-11-14. PMID:15954116. |
homeostatic interactions between dopamine and glutamate are central to the normal physiology of the basal ganglia. |
2005-11-14 |
2023-08-12 |
monkey |
| I G Sil'ki. [Possible mechanisms of involvement of the subthalamic nucleus and structures interconnected with this nucleus in movement disorders evoked by dopamine depletion]. Uspekhi fiziologicheskikh nauk. vol 36. issue 2. 2005-11-01. PMID:15909665. |
it is assumed that high-frequency stimulation of the stn can reduce or eliminate parkinsonian symptoms not only owing to inhibition of activity of gabaergic neurons in the output basal ganglia nuclei, projected into the thalamus or pedunculopontine nucleus, but also due to excitation of glutamatergic or cholinergic neurons in the output nuclei, and due to potentiation of excitatory inputs to preserved dopaminergic neurons and subsequent rise in dopamine concentration. |
2005-11-01 |
2023-08-12 |
Not clear |
| A J Lawrence, C L Parish, F Chen, D J Lodge, E V Krstew, K Card, D I Finkelstein, M K Horn. Chronic corticotropin-releasing factor type 1 receptor antagonism with antalarmin regulates the dopaminergic system of Fawn-Hooded rats. Journal of neurochemistry. vol 94. issue 6. 2005-10-27. PMID:16000149. |
following chronic antalarmin the density of dopaminergic terminals within the basal ganglia and amygdaloid complex were reduced, as was dopamine transporter binding within the striatum. |
2005-10-27 |
2023-08-12 |
rat |
| Jan Lewerenz, Bartosz Zurowski, Lars Jenicke, Tobias Bäumer, Andrew J Lees, Alexander Müncha. Lesion of the dorsorostral midbrain sparing the nigrostriatal tract mimics axial rigidity seen in progressive supranuclear palsy. Movement disorders : official journal of the Movement Disorder Society. vol 20. issue 8. 2005-10-19. PMID:15838851. |
we suggest that dorsorostral midbrain pathology rather than dopamine deficiency due to degeneration of nigrostriatal dopaminergic neurons or basal ganglia nuclei might be responsible for axial rigidity in extension. |
2005-10-19 |
2023-08-12 |
Not clear |
| Peter Salmi, Karima Chergui, Bertil B Fredhol. Adenosine-dopamine interactions revealed in knockout mice. Journal of molecular neuroscience : MN. vol 26. issue 2-3. 2005-10-14. PMID:16012197. |
neurochemical and pharmacological evidence obtained over the past 30 yr has indicated that adenosine and dopamine interact functionally in the basal ganglia and that such interactions have pathophysiological and therapeutic implications. |
2005-10-14 |
2023-08-12 |
mouse |
| R D S Prediger, C Da Cunha, R N Takahash. Antagonistic interaction between adenosine A2A and dopamine D2 receptors modulates the social recognition memory in reserpine-treated rats. Behavioural pharmacology. vol 16. issue 4. 2005-10-13. PMID:15961960. |
increasing evidence suggests that antagonistic interactions between specific subtypes of adenosine and dopamine receptors in the basal ganglia are involved in the control of motor activity. |
2005-10-13 |
2023-08-12 |
rat |
| Mathias Pessiglione, Dominique Guehl, Anne-Sophie Rolland, Chantal François, Etienne C Hirsch, Jean Féger, Léon Trembla. Thalamic neuronal activity in dopamine-depleted primates: evidence for a loss of functional segregation within basal ganglia circuits. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 6. 2005-09-26. PMID:15703406. |
the first is based on the higher firing rate and bursty firing pattern, and assumes that dopamine depletion results in a hyperactivity of basal ganglia (bg) output structures. |
2005-09-26 |
2023-08-12 |
monkey |
| Marcelo Betti Mascaro, Jackson Cioni Bittencourt, Cláudio Aparecido Casatti, Carol Fuzeti Elia. Alternative pathways for catecholamine action in oral motor control. Neuroscience letters. vol 386. issue 1. 2005-09-16. PMID:15978723. |
dopamine is of special interest since its imbalance may produce changes in basal ganglia activity, which generates abnormal movements, including jaw motor dysfunction, as in oral dyskinesia and possibly in bruxism. |
2005-09-16 |
2023-08-12 |
Not clear |
| Takashi Ohru. Preventive strategies for aspiration pneumonia in elderly disabled persons. The Tohoku journal of experimental medicine. vol 207. issue 1. 2005-09-14. PMID:16082150. |
similarly, since the production of substance p is regulated by dopaminergic neurons in the cerebral basal ganglia, treatment with dopamine analogs or potentiating drugs such as amantadine can reduce the incidence of pneumonia. |
2005-09-14 |
2023-08-12 |
human |
| b' Birim G\\xc3\\xbcnay Kili\\xc3\\xa. [Neuropsychology of attention deficit hyperactivity disorder: relevant theories and empirical studies]. Turk psikiyatri dergisi = Turkish journal of psychiatry. vol 16. issue 2. 2005-07-25. PMID:15981150.' |
dopamine and epinephrine as neurochemical factors and the frontal lobe and basal ganglia as anatomical factors have been found to be especially responsible. |
2005-07-25 |
2023-08-12 |
human |
| S M Brown, P D Kieffaber, C A Carroll, J L Vohs, J A Tracy, A Shekhar, B F O'Donnell, J E Steinmetz, W P Hetric. Eyeblink conditioning deficits indicate timing and cerebellar abnormalities in schizophrenia. Brain and cognition. vol 58. issue 1. 2005-07-21. PMID:15878730. |
accumulating evidence indicates that individuals with schizophrenia manifest abnormalities in structures (cerebellum and basal ganglia) and neurotransmitter systems (dopamine) linked to internal-timing processes. |
2005-07-21 |
2023-08-12 |
Not clear |