Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
C Warren Olanow, José A Obeso, Fabrizio Stocch. Drug insight: Continuous dopaminergic stimulation in the treatment of Parkinson's disease. Nature clinical practice. Neurology. vol 2. issue 7. 2006-09-15. PMID:16932589. |
dopaminergic neurons in the basal ganglia normally fire in a random but continuous manner, so that striatal dopamine concentrations are maintained at a relatively constant level. |
2006-09-15 |
2023-08-12 |
Not clear |
Gali Heimer, Michal Rivlin-Etzion, Izhar Bar-Gad, Joshua A Goldberg, Suzanne N Haber, Hagai Bergma. Dopamine replacement therapy does not restore the full spectrum of normal pallidal activity in the 1-methyl-4-phenyl-1,2,3,6-tetra-hydropyridine primate model of Parkinsonism. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 31. 2006-09-05. PMID:16885224. |
we therefore suggest that this imbalance reflects additional abnormal organization of the basal ganglia networks in response to dopamine replacement and may constitute the physiological substrate of the limitations and side effects of chronic drt. |
2006-09-05 |
2023-08-12 |
monkey |
C J Zeis. Neuroanatomical phenotyping in the mouse: the dopaminergic system. Veterinary pathology. vol 42. issue 6. 2006-08-01. PMID:16301571. |
one of these resides in the basal nuclei and their associated projections and utilizes dopamine as a neurotransmitter. |
2006-08-01 |
2023-08-12 |
mouse |
J L Short, C Ledent, E Borrelli, J Drago, A J Lawrenc. Genetic interdependence of adenosine and dopamine receptors: evidence from receptor knockout mice. Neuroscience. vol 139. issue 2. 2006-07-31. PMID:16476524. |
dopamine and adenosine receptors are known to share a considerable overlap in their regional distribution, being especially rich in the basal ganglia. |
2006-07-31 |
2023-08-12 |
mouse |
Aaron J Gruber, Peter Dayan, Boris S Gutkin, Sara A Soll. Dopamine modulation in the basal ganglia locks the gate to working memory. Journal of computational neuroscience. vol 20. issue 2. 2006-06-30. PMID:16699839. |
dopamine modulation in the basal ganglia locks the gate to working memory. |
2006-06-30 |
2023-08-12 |
human |
Aaron J Gruber, Peter Dayan, Boris S Gutkin, Sara A Soll. Dopamine modulation in the basal ganglia locks the gate to working memory. Journal of computational neuroscience. vol 20. issue 2. 2006-06-30. PMID:16699839. |
dopamine in the basal ganglia effectively locks this gate by influencing the stability of up and down states in the striatum. |
2006-06-30 |
2023-08-12 |
human |
R M Kostrzewa, P Nowak, J P Kostrzewa, R A Kostrzewa, R Bru. Peculiarities of L: -DOPA treatment of Parkinson's disease. Amino acids. vol 28. issue 2. 2006-05-24. PMID:15750845. |
l-dihydroxyphenylalanine (l: -dopa), the anti-parkinsonian drug affording the greatest symptomatic relief of parkinsonian symptoms, is still misunderstood in terms of its neurotoxic potential and the mechanism by which generated dopamine (da) is able to exert an effect despite the absence of da innervation of target sites in basal ganglia. |
2006-05-24 |
2023-08-12 |
rat |
Kendall H Lee, Charles D Blaha, Brent T Harris, Shannon Cooper, Frederick L Hitti, James C Leiter, David W Roberts, Uhnoh Ki. Dopamine efflux in the rat striatum evoked by electrical stimulation of the subthalamic nucleus: potential mechanism of action in Parkinson's disease. The European journal of neuroscience. vol 23. issue 4. 2006-05-09. PMID:16519665. |
taken together, these results suggest that enhanced dopamine release within the basal ganglia may be an important mechanism whereby high-frequency stimulation of the subthalamic nucleus improves motor symptoms of parkinson's disease. |
2006-05-09 |
2023-08-12 |
rat |
Jonathan W Min. Neurobiology of basal ganglia and Tourette syndrome: basal ganglia circuits and thalamocortical outputs. Advances in neurology. vol 99. 2006-05-09. PMID:16536354. |
in summary, the scheme of basal ganglia function presented here, in conjunction with known features of anatomical organization and dopamine neurotransmission provides a hypothesis for the pathophysiology of tics. |
2006-05-09 |
2023-08-12 |
Not clear |
Roger L Albi. Neurobiology of basal ganglia and Tourette syndrome: striatal and dopamine function. Advances in neurology. vol 99. 2006-05-09. PMID:16536355. |
neurobiology of basal ganglia and tourette syndrome: striatal and dopamine function. |
2006-05-09 |
2023-08-12 |
Not clear |
I G Sil'ki. [Role of the basal ganglia in the occurrence of paradoxical sleep dreams (hypothetical mechanism)]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 56. issue 1. 2006-05-03. PMID:16583673. |
this disinhibition is promoted by activation of dopaminergic cells by pedunculopontine neurons, subsequent rise in dopamine concentration in the input basal ganglia structure. |
2006-05-03 |
2023-08-12 |
Not clear |
I G Sil'ki. [Role of the basal ganglia in the occurrence of paradoxical sleep dreams (hypothetical mechanism)]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 56. issue 1. 2006-05-03. PMID:16583673. |
this selection is caused by modifiable action of dopamine on long-term changes in the efficacy of synaptic transmission during circulation of signals in closed interconnected loops, each of which includes one of the visual cortical areas (motor cortex), one of the thalamic nuclei, limbic and one of the visual areas (motor area) of the basal ganglia. |
2006-05-03 |
2023-08-12 |
Not clear |
Nicolas Mallet, Bérangère Ballion, Catherine Le Moine, François Gono. Cortical inputs and GABA interneurons imbalance projection neurons in the striatum of parkinsonian rats. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 14. 2006-04-26. PMID:16597742. |
therefore, dopamine degeneration induces a cascade of imbalances that spread out of the basal ganglia and affect the whole basal ganglia-thalamo-cortical circuits. |
2006-04-26 |
2023-08-12 |
rat |
Reidun Torp, Preet Bano Singh, Dag R Sørensen, Espen Dietrichs, Henry Hirschber. [Growth factors as neuroprotective treatment in Parkinson disease?]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke. vol 126. issue 7. 2006-04-11. PMID:16554879. |
the study reported here evaluates the ability of externally applied growth factors to protect the dopamine fibres in the basal ganglia in a toxin-induced animal model of the disease. |
2006-04-11 |
2023-08-12 |
Not clear |
S Body, K Asgari, J F Rickard, Z Zhang, K C F Fone, C M Bradshaw, E Szabad. Effects of quipazine and m-chlorophenylbiguanide (m-CPBG) on temporal differentiation: evidence for the involvement of 5-HT2A but not 5-HT3 receptors in interval timing behaviour. Psychopharmacology. vol 181. issue 2. 2006-04-10. PMID:15864559. |
there is evidence that 5-ht(3) receptors contribute to the regulation of dopamine release in the basal ganglia; however, it is not known whether 5-ht(3) receptor stimulation can influence temporal differentiation. |
2006-04-10 |
2023-08-12 |
Not clear |
G Benjelloun, L Jehel, G Abgrall, A Pelissolo, Jf Allilair. [Acute catatonic syndrome after neuroleptic malignant syndrome]. L'Encephale. vol 31. issue 6 Pt 1. 2006-03-10. PMID:16462690. |
neuroleptic malignant syndrome may be related to a dopamine deficiency, predominantly in the basal ganglia and antérior hypothalamus. |
2006-03-10 |
2023-08-12 |
Not clear |
J Baufreton, Z-T Zhu, M Garret, B Bioulac, S W Johnson, A I Taupigno. Dopamine receptors set the pattern of activity generated in subthalamic neurons. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 19. issue 13. 2006-03-07. PMID:16260646. |
using agonists of dopamine receptors in the d1 and d2 families on rat brain slices, we show that dopamine receptors in these two families govern the firing pattern of neurons in the subthalamic nucleus, a crucial part of the basal ganglia. |
2006-03-07 |
2023-08-12 |
rat |
Jeremy F Atherton, Mark D Beva. Ionic mechanisms underlying autonomous action potential generation in the somata and dendrites of GABAergic substantia nigra pars reticulata neurons in vitro. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 36. 2006-03-02. PMID:16148235. |
through their repetitive discharge, gabaergic neurons of the substantia nigra pars reticulata (snr) tonically inhibit the target nuclei of the basal ganglia and the dopamine neurons of the midbrain. |
2006-03-02 |
2023-08-12 |
rat |
Mikael Andersson, Anton Terasmaa, Kjell Fuxe, Ingrid Strömber. Subchronic haloperidol increases CB(1) receptor binding and G protein coupling in discrete regions of the basal ganglia. Journal of neuroscience research. vol 82. issue 2. 2006-02-24. PMID:16175569. |
the present study was designed to test whether chronic neuroleptic treatment, which is known to alter both expression and density of dopamine d(2) receptors in striatal regions, has effects upon function and binding level of the cannabinoid cb(1) receptor in the basal ganglia by using receptor autoradiography. |
2006-02-24 |
2023-08-12 |
Not clear |
C Daniel Salzman, Marina A Belova, Joseph J Pato. Beetles, boxes and brain cells: neural mechanisms underlying valuation and learning. Current opinion in neurobiology. vol 15. issue 6. 2006-01-20. PMID:16271457. |
neurons in the basal ganglia, in midbrain dopamine areas, in frontal and parietal cortices and in other brain areas, all modulate their activity in relation to aspects of learning. |
2006-01-20 |
2023-08-12 |
monkey |