| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Philip Win. How best to consider the structure and function of the pedunculopontine tegmental nucleus: evidence from animal studies. Journal of the neurological sciences. vol 248. issue 1-2. 2007-01-23. PMID:16765383. |
the former contains dopamine neurons that project widely within the basal ganglia while the latter is in receipt of corticostriatal output. |
2007-01-23 |
2023-08-12 |
Not clear |
| George W Hubert, Michael J Kuha. Colocalization of CART peptide with prodynorphin and dopamine D1 receptors in the rat nucleus accumbens. Neuropeptides. vol 40. issue 6. 2007-01-18. PMID:17064765. |
because cart has been shown to colocalize with substance p, a marker of the basal ganglia direct pathway, we now test for colocalization with other markers of the direct pathway to determine if cart colocalizes with dynorphin and dopamine d1 receptors. |
2007-01-18 |
2023-08-12 |
rat |
| Dorothée Domenger, Rainer K W Schwartin. The serial reaction time task in the rat: effects of D1 and D2 dopamine-receptor antagonists. Behavioural brain research. vol 175. issue 2. 2007-01-11. PMID:17011054. |
work with such tasks has shown that sequential behaviour seems to be mediated by specific brain systems, including the basal ganglia and the neurotransmitter dopamine. |
2007-01-11 |
2023-08-12 |
human |
| Wayne A Cass, Richard Grondin, Anders H Andersen, Zhiming Zhang, Peter A Hardy, Lindsay K Hussey-Andersen, William S Rayens, Greg A Gerhardt, Don M Gas. Iron accumulation in the striatum predicts aging-related decline in motor function in rhesus monkeys. Neurobiology of aging. vol 28. issue 2. 2007-01-09. PMID:16442671. |
these perturbations include alterations in dopamine (da) release, regulation and transport in the striatum and substantia nigra, striatal atrophy and elevated iron levels in the basal ganglia. |
2007-01-09 |
2023-08-12 |
monkey |
| Pershia Samadi, Paul J Bédard, Claude Rouillar. Opioids and motor complications in Parkinson's disease. Trends in pharmacological sciences. vol 27. issue 10. 2006-12-13. PMID:16908075. |
in animal models of parkinson's disease, dopamine denervation and repeated l-dopa administration are associated with an enhancement of opioid transmission in the basal ganglia. |
2006-12-13 |
2023-08-12 |
Not clear |
| George V Rebe. Behavioral electrophysiology of psychostimulants. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 11. 2006-12-12. PMID:16855534. |
the motor-activating effects of amphetamine and other psychostimulants such as cocaine depend on an increase in dopamine (da) transmission in the striatum, a key component of the basal ganglia and the forebrain motive circuit. |
2006-12-12 |
2023-08-12 |
Not clear |
| Brian S McKay, Brooke Goodman, Torsten Falk, Scott J Sherma. Retinal pigment epithelial cell transplantation could provide trophic support in Parkinson's disease: results from an in vitro model system. Experimental neurology. vol 201. issue 1. 2006-11-14. PMID:16764861. |
transplantation of retinal pigment epithelial (rpe) cells in the basal ganglia could provide a novel cell-based therapy for parkinson's disease by providing a constant source of dopamine replacement via the melanin synthetic pathway enzyme tyrosinase. |
2006-11-14 |
2023-08-12 |
human |
| Brian S McKay, Brooke Goodman, Torsten Falk, Scott J Sherma. Retinal pigment epithelial cell transplantation could provide trophic support in Parkinson's disease: results from an in vitro model system. Experimental neurology. vol 201. issue 1. 2006-11-14. PMID:16764861. |
these results indicate that transplantation rpe cells could potentially provide a dual benefit in parkinson's disease producing both dopamine and neurotrophic support of the basal ganglia. |
2006-11-14 |
2023-08-12 |
human |
| David J Scott, Mary M Heitzeg, Robert A Koeppe, Christian S Stohler, Jon-Kar Zubiet. Variations in the human pain stress experience mediated by ventral and dorsal basal ganglia dopamine activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 42. 2006-11-14. PMID:17050717. |
variations in the human pain stress experience mediated by ventral and dorsal basal ganglia dopamine activity. |
2006-11-14 |
2023-08-12 |
human |
| David J Scott, Mary M Heitzeg, Robert A Koeppe, Christian S Stohler, Jon-Kar Zubiet. Variations in the human pain stress experience mediated by ventral and dorsal basal ganglia dopamine activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 42. 2006-11-14. PMID:17050717. |
basal ganglia dopamine (da) neurotransmission may then respond to environmental events depending on their saliency, orienting the subsequent responses of the organism to both positive and negative stimuli. |
2006-11-14 |
2023-08-12 |
human |
| David J Scott, Mary M Heitzeg, Robert A Koeppe, Christian S Stohler, Jon-Kar Zubiet. Variations in the human pain stress experience mediated by ventral and dorsal basal ganglia dopamine activity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 42. 2006-11-14. PMID:17050717. |
these data demonstrate that basal ganglia dopamine d2 receptor-mediated neurotransmission is involved in responses to pain and that it contributes to individual variations in the pain experience at the levels of physical and emotional elements, albeit with different neuroanatomical substrates. |
2006-11-14 |
2023-08-12 |
human |
| Naila Ismayilova, Alexei Verkhratsky, Michael J Dascomb. Changes in mGlu5 receptor expression in the basal ganglia of reserpinised rats. European journal of pharmacology. vol 545. issue 2-3. 2006-11-13. PMID:16890937. |
dopamine depletion in parkinson's disease results in a series of pathophysiological changes in the basal ganglia circuitry. |
2006-11-13 |
2023-08-12 |
rat |
| A N Talalaenko, G K Krivobok, D V Pankrat'ev, N V Goncharenk. Neurochemical mechanisms of the dorsal pallidum in the antiaversive effects of anxiolytics in various models of anxiety. Neuroscience and behavioral physiology. vol 36. issue 7. 2006-10-31. PMID:16841156. |
dopamine, apomorphine, gaba, chlordiazepoxide, phenibut, and indoter injected locally into this formation of the basal ganglia had no effect on the mechanisms of voluntary movement but counteracted anxiety states in both behavioral models. |
2006-10-31 |
2023-08-12 |
rat |
| Ubaldo Bonuccelli, Paolo Del Dott. New pharmacologic horizons in the treatment of Parkinson disease. Neurology. vol 67. issue 7 Suppl 2. 2006-10-30. PMID:17030738. |
the nonphysiologic pulsatile stimulation of striatal dopamine receptors, produced by the currently available dopaminergic drugs, may trigger a dysregulation of many neurotransmitter systems within the basal ganglia, mainly localized on medium spiny striatal neurons. |
2006-10-30 |
2023-08-12 |
Not clear |
| G Heimer, M Rivlin, Z Israel, H Bergma. Synchronizing activity of basal ganglia and pathophysiology of Parkinson's disease. Journal of neural transmission. Supplementum. issue 70. 2006-10-24. PMID:17017503. |
we conclude that the normal fluctuation of basal ganglia dopamine levels combined with local cortico-striatal learning rules lead to noncorrelated activity in the pallidum. |
2006-10-24 |
2023-08-12 |
human |
| J V Jacobs, F B Hora. Abnormal proprioceptive-motor integration contributes to hypometric postural responses of subjects with Parkinson's disease. Neuroscience. vol 141. issue 2. 2006-10-04. PMID:16713110. |
medication did not consistently improve the length and accuracy of the parkinson's disease subjects' compensatory steps, suggesting that degeneration of dopamine circuits within the basal ganglia is not responsible for the proprioceptive-motor deficit that degrades compensatory steps in parkinson's disease subjects. |
2006-10-04 |
2023-08-12 |
human |
| Agnes Nadjar, Jonathan M Brotchie, Celine Guigoni, Qin Li, Shao-Bo Zhou, Gui-Jie Wang, Paula Ravenscroft, François Georges, Alan R Crossman, Erwan Bezar. Phenotype of striatofugal medium spiny neurons in parkinsonian and dyskinetic nonhuman primates: a call for a reappraisal of the functional organization of the basal ganglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 34. 2006-09-28. PMID:16928853. |
the classic view of anatomofunctional organization of the basal ganglia is that striatopallidal neurons of the "indirect" pathway express d2 dopamine receptors and corelease enkephalin with gaba, whereas striatopallidal neurons of the "direct" pathway bear d1 dopamine receptors and corelease dynorphin and substance p with gaba. |
2006-09-28 |
2023-08-12 |
Not clear |
| Agnes Nadjar, Jonathan M Brotchie, Celine Guigoni, Qin Li, Shao-Bo Zhou, Gui-Jie Wang, Paula Ravenscroft, François Georges, Alan R Crossman, Erwan Bezar. Phenotype of striatofugal medium spiny neurons in parkinsonian and dyskinetic nonhuman primates: a call for a reappraisal of the functional organization of the basal ganglia. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 34. 2006-09-28. PMID:16928853. |
although many studies have investigated the pathophysiology of the basal ganglia after dopamine denervation and subsequent chronic levodopa (l-dopa) treatment, none has ever considered the possibility of plastic changes leading to profound reorganization and/or biochemical phenotype modifications of medium spiny neurons. |
2006-09-28 |
2023-08-12 |
Not clear |
| Genela Morris, Alon Nevet, David Arkadir, Eilon Vaadia, Hagai Bergma. Midbrain dopamine neurons encode decisions for future action. Nature neuroscience. vol 9. issue 8. 2006-09-27. PMID:16862149. |
current models of the basal ganglia and dopamine neurons emphasize their role in reinforcement learning. |
2006-09-27 |
2023-08-12 |
monkey |
| Genela Morris, Alon Nevet, David Arkadir, Eilon Vaadia, Hagai Bergma. Midbrain dopamine neurons encode decisions for future action. Nature neuroscience. vol 9. issue 8. 2006-09-27. PMID:16862149. |
because dopamine neurons do not have spatial or motor properties, we conclude that immediate decisions are likely to be generated elsewhere and conveyed to the dopamine neurons, which play a role in shaping long-term decision policy through dynamic modulation of the efficacy of basal ganglia synapses. |
2006-09-27 |
2023-08-12 |
monkey |