| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Martínez-García, B García-Iglesias, J A Terró. Effect of central serotonin depletion on 5-HT receptor-mediated vasomotor responses in the middle meningeal artery of anaesthetized rats. Autonomic & autacoid pharmacology. vol 29. issue 1-2. 2009-06-08. PMID:19302555. |
this study analysed the effect of chemical lesion of the 5-ht system in the brain with 5,7-dihydroxytryptamine (5,7-dht) on 5-ht receptor-mediated dilator responses to 5-carboxamidotryptamine (5-ct) in the middle meningeal artery of anaesthetized rats. |
2009-06-08 |
2023-08-12 |
rat |
| Stella Manta, Jianming Dong, Guy Debonnel, Pierre Blie. Optimization of vagus nerve stimulation parameters using the firing activity of serotonin neurons in the rat dorsal raphe. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 19. issue 4. 2009-05-20. PMID:19150228. |
various stimulation parameters were thus tested on their capacity to enhance 5-ht neuronal firing because of the delayed action of vns on the 5-ht system and its important role in the antidepressant response. |
2009-05-20 |
2023-08-12 |
rat |
| Heidi M Rivera, Denesa R Oberbeck, Bumsup Kwon, Thomas A Houpt, Lisa A Ecke. Estradiol increases Pet-1 and serotonin transporter mRNA in the midbrain raphe nuclei of ovariectomized rats. Brain research. vol 1259. 2009-04-21. PMID:19168037. |
to examine further the putative relationship between estradiol and 5-ht, we investigated whether estradiol increases the expression of pet-1 and the 5-ht transporter (5-htt), two genes implicated in the development and regulation of the 5-ht system. |
2009-04-21 |
2023-08-12 |
rat |
| Dennis L Murphy, Meredith A Fox, Kiara R Timpano, Pablo R Moya, Renee Ren-Patterson, Anne M Andrews, Andrew Holmes, Klaus-Peter Lesch, Jens R Wendlan. How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, which functions to influence all cellular serotonin systems. Neuropharmacology. vol 55. issue 6. 2009-04-14. PMID:18824000. |
the serotonin transporter (sert) has been the most comprehensively studied of the serotonin system molecular components, and will be the primary focus of this review. |
2009-04-14 |
2023-08-12 |
mouse |
| Nasser Haddjeri, Pierre Blie. Neurokinin-1 receptor antagonists modulate brain noradrenaline and serotonin interactions. European journal of pharmacology. vol 600. issue 1-3. 2009-03-27. PMID:18930727. |
attenuated the responsiveness of dorsal raphe 5-ht(1a) autoreceptors, lesioning noradrenaline neurons with the neurotoxin n-(2-chloroethyl)-n-ethyl-2-bromobenzylamine (dsp-4) prevented the enhancing action of a 2-day treatment with cp-96,345 on 5-ht neuronal firing, suggesting that tachykinin nk1 receptor antagonists influence 5-ht system via noradrenaline neurons independently of their firing rate. |
2009-03-27 |
2023-08-12 |
rat |
| Daniela Eser, Gregor Leicht, Thomas Baghai, Oliver Pogarell, Cornelius Schüle, Susanne Karch, Caroline Nothdurfter, Rainer Rupprecht, Christoph Muler. Impact of loudness dependency of auditory evoked potentials on the panic response to CCK-4. Journal of psychiatric research. vol 43. issue 4. 2009-03-18. PMID:18534623. |
in line with the serotonin (5-ht)-hypothesis of panic disorder it has been suggested that the panicogenic effects of cck-4 are mediated in part through the 5-ht system. |
2009-03-18 |
2023-08-12 |
Not clear |
| G M Orabona, K Griesi-Oliveira, E Vadasz, V L S Bulcão, V N V O Takahashi, E S Moreira, M Furia-Silva, A M S Ros-Melo, F Dourado, S R Matioli, R Matioli, P Otto, M R Passos-Buen. HTR1B and HTR2C in autism spectrum disorders in Brazilian families. Brain research. vol 1250. 2009-02-27. PMID:19038234. |
several studies suggest the involvement of the serotonin system in the development of asd, but only few have investigated serotonin receptors. |
2009-02-27 |
2023-08-12 |
Not clear |
| Jhodie R Duncan, David S Paterson, Hannah C Kinne. The development of nicotinic receptors in the human medulla oblongata: inter-relationship with the serotonergic system. Autonomic neuroscience : basic & clinical. vol 144. issue 1-2. 2009-02-20. PMID:18986852. |
in this study we analyzed the inter-relationship between nicotinic receptors (nachrs), to which nicotine in cigarette smoke bind, and the medullary 5-ht system in the human fetus and infant as a step towards determining the mechanisms whereby smoking increases sids risk in infants with 5-ht defects. |
2009-02-20 |
2023-08-12 |
human |
| Anu Koskela, Tomi Kauppinen, Anna Keski-Rahkonen, Elina Sihvola, Jaakko Kaprio, Aila Rissanen, Aapo Ahone. Brain serotonin transporter binding of [123I]ADAM: within-subject variation between summer and winter data. Chronobiology international. vol 25. issue 5. 2009-01-14. PMID:18780196. |
the neurotransmitter serotonin (5-ht) controls several physiological functions, and a disturbance of the 5-ht system is implicated in many psychiatric conditions. |
2009-01-14 |
2023-08-12 |
Not clear |
| Jacqueline Bor. Molecular imaging of the 5-HT(1A) receptor in relation to human cognition. Behavioural brain research. vol 195. issue 1. 2009-01-12. PMID:18606193. |
pharmacological challenge studies using 5-ht(1a) agonism and antagonism to manipulate the serotonin system support involvement of the 5-ht(1a) receptor in human cognition, mainly in verbal memory functioning. |
2009-01-12 |
2023-08-12 |
human |
| William H J Norton, Anja Folchert, Laure Bally-Cui. Comparative analysis of serotonin receptor (HTR1A/HTR1B families) and transporter (slc6a4a/b) gene expression in the zebrafish brain. The Journal of comparative neurology. vol 511. issue 4. 2008-12-30. PMID:18839395. |
our analysis of serotonin transporter (sert)-encoding genes also identifies parallel genetic pathways used to build the 5-ht system in zebrafish. |
2008-12-30 |
2023-08-12 |
zebrafish |
| Hélène Bras, Susana P Gaytán, Paule Portalier, Sébastien Zanella, Rosario Pásaro, Patrice Coulon, Gérard Hilair. Prenatal activation of 5-HT2A receptor induces expression of 5-HT1B receptor in phrenic motoneurons and alters the organization of their premotor network in newborn mice. The European journal of neuroscience. vol 28. issue 6. 2008-12-15. PMID:18783379. |
in newborn mice of the control [c3h/hej (c3h)] and monoamine oxidase a-deficient (tg8) strains, in which levels of endogenous serotonin (5-ht) were drastically increased, we investigated how 5-ht system dysregulation affected the maturation of phrenic motoneurons (phmns), which innervate the diaphragm. |
2008-12-15 |
2023-08-12 |
mouse |
| N K Popov. From gene to aggressive behavior: the role of brain serotonin. Neuroscience and behavioral physiology. vol 38. issue 5. 2008-12-09. PMID:18607754. |
the role of protein elements of the brain serotonin system (key enzymes in serotonin metabolism and serotonin 5-ht(1a) receptors), which are subject to the direct influence of genes, in the genetic predisposition to aggressive behavior is discussed. |
2008-12-09 |
2023-08-12 |
mouse |
| Y Dempsie, M R MacLea. Pulmonary hypertension: therapeutic targets within the serotonin system. British journal of pharmacology. vol 155. issue 4. 2008-11-25. PMID:18536742. |
this review will discuss our current understanding of 'the serotonin hypothesis' of pah and highlight possible therapeutic targets within the serotonin system. |
2008-11-25 |
2023-08-12 |
Not clear |
| Laurence Lanfumey, Raymond Mongeau, Charles Cohen-Salmon, Michel Hamo. Corticosteroid-serotonin interactions in the neurobiological mechanisms of stress-related disorders. Neuroscience and biobehavioral reviews. vol 32. issue 6. 2008-11-05. PMID:18534678. |
the review provides an overview of the hpa axis and the 5-ht system organization, focusing on the 5-ht(1a) receptors, which play a pivotal role in the 5-ht system regulation and its response to stress. |
2008-11-05 |
2023-08-12 |
Not clear |
| Ai-Ming Y. Indolealkylamines: biotransformations and potential drug-drug interactions. The AAPS journal. vol 10. issue 2. 2008-11-03. PMID:18454322. |
indolealkylamine (iaa) drugs are 5-hydroxytryptamine (5-ht or serotonin) analogs that mainly act on the serotonin system. |
2008-11-03 |
2023-08-12 |
Not clear |
| Yasuharu Kimura, Yuki Naitou, Fumikazu Wanibuchi, Tokio Yamaguch. 5-HT(2C) receptor activation is a common mechanism on proerectile effects of apomorphine, oxytocin and melanotan-II in rats. European journal of pharmacology. vol 589. issue 1-3. 2008-10-24. PMID:18582863. |
in addition, in order to clarify further the suggestion that the 5-ht pathway projecting from medulla oblongata to lumbosacral spinal site and lumbosacral 5-ht(2c) receptor are involved in the induction of penile erection, we also examined the proerectile effect of ym348 in spinal and a 5-ht depletor, p-chlorophenyl alanine (pcpa)-treated rats. |
2008-10-24 |
2023-08-12 |
rat |
| Yasuharu Kimura, Yuki Naitou, Fumikazu Wanibuchi, Tokio Yamaguch. 5-HT(2C) receptor activation is a common mechanism on proerectile effects of apomorphine, oxytocin and melanotan-II in rats. European journal of pharmacology. vol 589. issue 1-3. 2008-10-24. PMID:18582863. |
these results suggest that 5-ht(2c) receptor in lumbosacral spinal sites mediates not only dopamine-oxytocin-5-ht action but melanocortin action on penile erections, and that the 5-ht pathway is located downstream from melanocortin pathway as well as the dopamine-oxytocin pathway. |
2008-10-24 |
2023-08-12 |
rat |
| Jorge Mendoza, Daniel Clesse, Paul Pévet, Etienne Challe. Serotonergic potentiation of dark pulse-induced phase-shifting effects at midday in hamsters. Journal of neurochemistry. vol 106. issue 3. 2008-09-15. PMID:18498439. |
because behavioral resetting may be mediated in part by 5-ht inputs to the scn, here we determined whether 5-ht system can modulate dark-induced phase-shifts in syrian hamsters housed in ll. |
2008-09-15 |
2023-08-12 |
Not clear |
| Yael Dvir, Patrick Smallwoo. Serotonin syndrome: a complex but easily avoidable condition. General hospital psychiatry. vol 30. issue 3. 2008-08-11. PMID:18433663. |
the etiology is often the result of therapeutic drug use, intentional overdosing of serotonergic agents or complex interactions between drugs that directly or indirectly modulate the serotonin system (boyer ew, shannon m. the serotonin syndrome. |
2008-08-11 |
2023-08-12 |
Not clear |