| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gerhard Magnus, Junling Xing, Yueping Zhang, Victor Z Ha. Diversity of cellular physiology and morphology of Purkinje cells in the adult zebrafish cerebellum. The Journal of comparative neurology. 2022-12-01. PMID:36453181. |
diversity of cellular physiology and morphology of purkinje cells in the adult zebrafish cerebellum. |
2022-12-01 |
2023-08-14 |
zebrafish |
| Gerhard Magnus, Junling Xing, Yueping Zhang, Victor Z Ha. Diversity of cellular physiology and morphology of Purkinje cells in the adult zebrafish cerebellum. The Journal of comparative neurology. 2022-12-01. PMID:36453181. |
this study was designed to explore the functional circuitry of the adult zebrafish cerebellum, focusing on its purkinje cells and using whole-cell patch recordings and single cell labeling in slice preparations. |
2022-12-01 |
2023-08-14 |
zebrafish |
| Gabriel G Cataldi, Setiembre D Elorza, Ana Toledano-Zaragoza, Soledad de Olmos, Andrea B Cragnolini, Mauricio G Martí. Cholesterol-24-hydroxylase (CYP46) in the old brain: Analysis of positive populations and factors triggering its expression in astrocytes. The Journal of comparative neurology. 2022-12-01. PMID:36453552. |
we found that cyp46 is localized in the same neuronal populations in young and old brains, mainly in the hippocampus, in cortical layers, and in purkinje neurons of the cerebellum. |
2022-12-01 |
2023-08-14 |
mouse |
| Teruyoshi Hirayama, Yuuki Kadooka, Etsuko Tarusawa, Sei Saitoh, Hisako Nakayama, Natsumi Hoshino, Soichiro Nakama, Takahiro Fukuishi, Yudai Kawanishi, Hiroki Umeshima, Koichi Tomita, Yumiko Yoshimura, Niels Galjart, Kouichi Hashimoto, Nobuhiko Ohno, Takeshi Yag. CTCF loss induces giant lamellar bodies in Purkinje cell dendrites. Acta neuropathologica communications. vol 10. issue 1. 2022-11-29. PMID:36447271. |
in the mature cerebellum, ctcf is highly expressed in purkinje cells (pcs) as compared with other cerebellar neurons. |
2022-11-29 |
2023-08-14 |
mouse |
| Sanni Hansen, Emil Olsen, Marie Raundal, Jørgen Steen Agerhol. Cerebellar abiotrophy in an Icelandic horse. Acta veterinaria Scandinavica. vol 64. issue 1. 2022-11-26. PMID:36435777. |
cerebellar abiotrophy (ca) is an uncommon hereditary neurodegenerative disorder affecting the cerebellar purkinje cells. |
2022-11-26 |
2023-08-14 |
Not clear |
| Jesse I Gilmer, Michael A Farries, Zachary Kilpatrick, Ioannis Delis, Jeremy D Cohen, Abigail L Perso. An emergent temporal basis set robustly supports cerebellar time-series learning. Journal of neurophysiology. 2022-11-23. PMID:36416445. |
theoretical work has proposed that the cerebellum's input recipient structure, the granule cell layer (gcl), performs pattern separation of inputs that facilitates learning in purkinje cells (p-cells). |
2022-11-23 |
2023-08-14 |
Not clear |
| Zhengcheng Huang, Shuai Wang, Yiyu Yang, Jianwei Lou, Zhaoxiong Liu, Zhidan Liu, Hui Yong, Shulin Shan, Fuyong Son. Mitochondrial dysfunction promotes the necroptosis of Purkinje cells in the cerebellum of acrylamide-exposed rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022-11-23. PMID:36417989. |
mitochondrial dysfunction promotes the necroptosis of purkinje cells in the cerebellum of acrylamide-exposed rats. |
2022-11-23 |
2023-08-14 |
human |
| Zhengcheng Huang, Shuai Wang, Yiyu Yang, Jianwei Lou, Zhaoxiong Liu, Zhidan Liu, Hui Yong, Shulin Shan, Fuyong Son. Mitochondrial dysfunction promotes the necroptosis of Purkinje cells in the cerebellum of acrylamide-exposed rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2022-11-23. PMID:36417989. |
purkinje cells are the only efferent source of cerebellum, and their output is responsible for coordinating motor activity. |
2022-11-23 |
2023-08-14 |
human |
| Vasiliki Tellios, Matthew J E Maksoud, Ravneet Nagra, Gurneet Jassal, Wei-Yang L. Neuronal Nitric Oxide Synthase Critically Regulates the Endocannabinoid Pathway in the Murine Cerebellum During Development. Cerebellum (London, England). 2022-11-19. PMID:36402869. |
the predominant ecb within the cerebellum, 2-arachidonoylglycerol (2-ag), is produced by a metabotropic glutamate receptor type 1 (mglur1)-initiated signaling cascade within purkinje neurons (pns). |
2022-11-19 |
2023-08-14 |
mouse |
| Chenfei Lyu, Chencen Yu, Guanglong Sun, Yue Zhao, Ruolan Cai, Hao Sun, Xintai Wang, Guoqiang Jia, Lingzhu Fan, Xi Chen, Lin Zhou, Ying Shen, Lixia Gao, Xinjian L. Deconstruction of Vermal Cerebellum in Ramp Locomotion in Mice. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2022-11-14. PMID:36373709. |
here, it has been imaged the neuronal activity of cerebellar molecular interneurons (mlis) and purkinje cells (pcs) using a miniaturized microscope while a mouse is walking on a slope. |
2022-11-14 |
2023-08-14 |
mouse |
| M J Ottenhoff, S Dijkhuizen, A C H Ypelaar, N L de Oude, S K E Koekkoek, S S-H Wang, C I De Zeeuw, Y Elgersma, H J Boel. Cerebellum-dependent associative learning is not impaired in a mouse model of neurofibromatosis type 1. Scientific reports. vol 12. issue 1. 2022-11-09. PMID:36351971. |
the cerebellum plays a pivotal role in motor functioning and the nf1 gene is highly expressed in cerebellar purkinje cells. |
2022-11-09 |
2023-08-14 |
mouse |
| Ri Wang, Chao Liu, Wenyan Guo, Lixuan Wang, Siruan Chen, Jiaojiao Zhao, Xia Qin, Wanjun Bai, Zuxiao Yang, Dezhi Kong, Zhanfeng Jia, Shufeng Liu, Wei Zhan. Movement disorder caused by FRRS1L deficiency may be associated with morphological and functional disorders in Purkinje cells. Brain research bulletin. vol 191. 2022-11-04. PMID:36330921. |
deletion also impairs purkinje cell dendritic spine formation and ampar expression in the cerebellum and damages the electrophysiological discharge rhythm of purkinje cells. |
2022-11-04 |
2023-08-14 |
mouse |
| Ayane Ninomiya, Izuki Amano, Michifumi Kokubo, Yusuke Takatsuru, Sumiyasu Ishii, Hirokazu Hirai, Nobutake Hosoi, Noriyuki Koibuch. Long-term depression-inductive stimulation causes long-term potentiation in mouse Purkinje cells with a mutant thyroid hormone receptor. Proceedings of the National Academy of Sciences of the United States of America. vol 119. issue 45. 2022-11-02. PMID:36322758. |
here, we report specific th effects on functional development of the cerebellum by using transgenic mice overexpressing a dominant-negative tr (mf-1) specifically in cerebellar purkinje cells (pcs). |
2022-11-02 |
2023-08-14 |
mouse |
| Lisa E L Romano, Wen Yih Aw, Kathryn M Hixson, Tatiana V Novoselova, Tammy M Havener, Stefanie Howell, Bonnie Taylor-Blake, Charlotte L Hall, Lei Xing, Josh Beri, Suran Nethisinghe, Laura Perna, Abubakar Hatimy, Ginevra Chioccioli Altadonna, Lee M Graves, Laura E Herring, Anthony J Hickey, Konstantinos Thalassinos, J Paul Chapple, Justin M Wolte. Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization. Cell reports. vol 41. issue 5. 2022-11-02. PMID:36323248. |
arsacs mice possess mislocalization of itga1 in purkinje neurons and synaptic disorganization in the deep cerebellar nucleus (dcn). |
2022-11-02 |
2023-08-14 |
mouse |
| Claire M Wade, Annie Y H Pan, Rosanne M Taylor, Peter Williamso. Cerebellar Abiotrophy in Australian Working Kelpies Is Associated with Two Major Risk Loci. Genes. vol 13. issue 10. 2022-10-27. PMID:36292596. |
an autosomal recessive form of inherited cerebellar abiotrophy (ca) that is characterized by a degeneration of purkinje and granule cells in the cerebellar cortex occurs in the australian working kelpie dog breed. |
2022-10-27 |
2023-08-14 |
dog |
| Amira I Shrief, Ahmed A M Abdel-Hamid, Am Moustafa, E El-Mohande. The possible protective role of pimpinella anisum oil versus selenium on aspartame induced changes in rat cerebellar cortex: histological, immunohistochemical and electron microscopic study. Ultrastructural pathology. 2022-10-23. PMID:36273246. |
the administration of asp for 2 months (group ii) resulted in cerebellar histopathological changes in the form of deformed purkinje and granule cells. |
2022-10-23 |
2023-08-14 |
rat |
| William Miller, Charles Lewis Humphrey Pruett, William Stone, Cindy Eide, Megan Riddle, Courtney Popp, Matthew Yousefzadeh, Christopher Lees, Davis Seelig, Elizabeth Thompson, Harry Orr, Laura Niedernhofer, Jakub Tola. Accumulation of senescence observed in spinocerebellar ataxia type 7 mouse model. PloS one. vol 17. issue 10. 2022-10-17. PMID:36251631. |
sca7 predominantly causes a loss of photoreceptors in the retina and purkinje cells of the cerebellum. |
2022-10-17 |
2023-08-14 |
mouse |
| Regina T Martuscello, Karthigayini Sivaprakasam, Whitney Hartstone, Sheng-Han Kuo, Genevieve Konopka, Elan D Louis, Phyllis L Faus. Gene Expression Analysis of Laser-Captured Purkinje Cells in the Essential Tremor Cerebellum. Cerebellum (London, England). 2022-10-15. PMID:36242761. |
gene expression analysis of laser-captured purkinje cells in the essential tremor cerebellum. |
2022-10-15 |
2023-08-14 |
Not clear |
| Regina T Martuscello, Karthigayini Sivaprakasam, Whitney Hartstone, Sheng-Han Kuo, Genevieve Konopka, Elan D Louis, Phyllis L Faus. Gene Expression Analysis of Laser-Captured Purkinje Cells in the Essential Tremor Cerebellum. Cerebellum (London, England). 2022-10-15. PMID:36242761. |
through comprehensive studies in postmortem brains, we identified major morphological changes in the et cerebellum that reflect cellular damage in purkinje cells (pcs), suggesting that pc damage is central to et pathogenesis. |
2022-10-15 |
2023-08-14 |
Not clear |
| Rosario Baltazar-Lara, Janeth Mora Zenil, Martha Carranza, José Ávila-Mendoza, Carlos G Martínez-Moreno, Carlos Arámburo, Maricela Lun. Growth Hormone (GH) Crosses the Blood-Brain Barrier (BBB) and Induces Neuroprotective Effects in the Embryonic Chicken Cerebellum after a Hypoxic Injury. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232848. |
in the cerebellum, cy3-gh and gh receptor (ghr) co-localized in the granular and purkinje layers and in deep cerebellar nuclei under hypoxic conditions, suggesting direct actions. |
2022-10-14 |
2023-08-14 |
chicken |