| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kota Nakamura, Mako Beppu, Kaori Sakai, Hayata Yagyu, Saori Matsumaru, Takao Kohno, Mitsuharu Hattor. The C-terminal region of Reelin is necessary for proper positioning of a subset of Purkinje cells in the postnatal cerebellum. Neuroscience. vol 336. 2017-10-12. PMID:27586054. |
in the normal cerebellum, purkinje cells (pcs) are generated in a zone along the ventricular surface, migrate radially, and align to form a single-cell layer. |
2017-10-12 |
2023-08-13 |
mouse |
| L J Schep, R J Slaughter, S Galea, D Newcomb. Ibogaine for treating drug dependence. What is a safe dose? Drug and alcohol dependence. vol 166. 2017-10-11. PMID:27426011. |
high doses of ibogaine act on several classes of neurological receptors and transporters to achieve pharmacological responses associated with drug aversion; limited toxicology research suggests that intraperitoneal doses used to successfully treat rodents, for example, have also been shown to cause neuronal injury (purkinje cells) in the rat cerebellum. |
2017-10-11 |
2023-08-13 |
rat |
| Carmen Rubio-Osornio, Aldo Eguiluz-Meléndez, Cristina Trejo-Solís, Veronica Custodio, Moises Rubio-Osornio, Artemio Rosiles-Abonce, Juan C Martínez-Lazcano, Edith González, Carlos Pa. Decreased Expression of Sox-1 in Cerebellum of Rat with Generalized Seizures Induced by Kindling Model. CNS & neurological disorders drug targets. vol 15. issue 6. 2017-10-03. PMID:26996170. |
particularly in cerebellum, sox-1 plays a key role in the bergmann´s glia (bg) function, which allows the correct function of the purkinje cells (pc). |
2017-10-03 |
2023-08-13 |
mouse |
| Ludovic Telley, Christelle Cadilhac, Jean-Michel Cioni, Veronique Saywell, Céline Jahannault-Talignani, Rosa E Huettl, Catherine Sarrailh-Faivre, Alexandre Dayer, Andrea B Huber, Fabrice Ang. Dual Function of NRP1 in Axon Guidance and Subcellular Target Recognition in Cerebellum. Neuron. vol 91. issue 6. 2017-10-03. PMID:27618676. |
in cerebellum, basket cells (bcs) innervate the soma and axon initial segment (ais) of purkinje cells (pcs) to form the pinceau synapse, but the underlying mechanisms remain incompletely understood. |
2017-10-03 |
2023-08-13 |
Not clear |
| Kelly Barford, Chan Choo Yap, Noelle D Dwyer, Bettina Winckle. The related neuronal endosomal proteins NEEP21 (Nsg1) and P19 (Nsg2) have divergent expression profiles in vivo. The Journal of comparative neurology. vol 525. issue 8. 2017-09-29. PMID:28299779. |
in the cerebellum, neep21/nsg1 expression becomes largely restricted to purkinje neurons in adulthood whereas p19/nsg2 expression strikingly disappears from the cerebellum with age. |
2017-09-29 |
2023-08-13 |
mouse |
| James Cairns, Doug Swanson, Joanna Yeung, Anna Sinova, Ronny Chan, Praneetha Potluri, Price Dickson, Guy Mittleman, Dan Goldowit. Abnormalities in the Structure and Function of Cerebellar Neurons and Neuroglia in the Lc/+ Chimeric Mouse Model of Variable Developmental Purkinje Cell Loss. Cerebellum (London, England). vol 16. issue 1. 2017-09-26. PMID:26837618. |
common cerebellar pathology observed in autistic individuals includes variable loss of cerebellar purkinje cells (pcs) and increased numbers of reactive neuroglia in the cerebellum and cortical brain regions. |
2017-09-26 |
2023-08-13 |
mouse |
| Anna Sługocka, Jan Wiaderkiewicz, Jaroslaw J Barsk. Genetic Targeting in Cerebellar Purkinje Cells: an Update. Cerebellum (London, England). vol 16. issue 1. 2017-09-26. PMID:26969183. |
since the last review paper published in cerebellum in 2002 [1], there has been a substantial increase in the number of experiments utilizing transgenic manipulations in murine cerebellar purkinje cells. |
2017-09-26 |
2023-08-13 |
mouse |
| Jeanelle Ariza, Hailee Rogers, Angela Monterrubio, Adriana Reyes-Miranda, Paul J Hagerman, Verónica Martínez-Cerdeñ. A Majority of FXTAS Cases Present with Intranuclear Inclusions Within Purkinje Cells. Cerebellum (London, England). vol 15. issue 5. 2017-09-25. PMID:27108270. |
inclusions are present in neurons throughout the brain but are widely believed not to be present in the purkinje cells (pcs) of the cerebellum. |
2017-09-25 |
2023-08-13 |
Not clear |
| Amelia Burroughs, Andrew K Wise, Jianqiang Xiao, Conor Houghton, Tianyu Tang, Colleen Y Suh, Eric J Lang, Richard Apps, Nadia L Cerminar. The dynamic relationship between cerebellar Purkinje cell simple spikes and the spikelet number of complex spikes. The Journal of physiology. vol 595. issue 1. 2017-09-25. PMID:27265808. |
this dynamic interaction has important implications for cerebellar information processing, and suggests that complex spike spikelet number may maintain purkinje cells within their operational range. |
2017-09-25 |
2023-08-13 |
Not clear |
| Qian Liu, Mei Jiang, Yi Kuang, Xiaoqiong Shu, Jun Li, Matthew W Li, Hedong L. Dicer1 Ablation Impairs Responsiveness of Cerebellar Granule Neuron Precursors to Sonic Hedgehog and Disrupts Expression of Distinct Cell Cycle Regulator Genes. Cerebellum (London, England). vol 16. issue 2. 2017-09-22. PMID:27600805. |
granule neuron precursors (gnps) proliferate under the influence of sonic hedgehog (shh) that is secreted by purkinje neurons during early postnatal cerebellar development. |
2017-09-22 |
2023-08-13 |
human |
| E Y Scott, M C T Penedo, J D Murray, C J Finn. Defining Trends in Global Gene Expression in Arabian Horses with Cerebellar Abiotrophy. Cerebellum (London, England). vol 16. issue 2. 2017-09-22. PMID:27709457. |
equine cerebellar abiotrophy (ca) is a hereditary neurodegenerative disease that affects the purkinje neurons of the cerebellum and causes ataxia in arabian foals. |
2017-09-22 |
2023-08-13 |
Not clear |
| Jurairat Khongrum, Jintanaporn Wattanathor. Laser Acupuncture at HT7 Improves the Cerebellar Disorders in Valproic Acid-Rat Model of Autism. Journal of acupuncture and meridian studies. vol 10. issue 4. 2017-09-21. PMID:28889839. |
the results showed that laser acupuncture ht7 decreased oxidative stress, il-6 expression, and gaba-t activity but increased the expressions of gad 65 kda together with the density of purkinje cells in the cerebellum. |
2017-09-21 |
2023-08-13 |
rat |
| Samantha B Amat, Matthew J M Rowan, Michael A Gaffield, Audrey Bonnan, Chikako Kikuchi, Hiroki Taniguchi, Jason M Christi. Using c-kit to genetically target cerebellar molecular layer interneurons in adult mice. PloS one. vol 12. issue 6. 2017-09-20. PMID:28658323. |
purkinje cells (pcs) provide the sole output of the cerebellar cortex, therefore, any cerebellar involvement in motor activity must be driven by changes in pc firing rates. |
2017-09-20 |
2023-08-13 |
mouse |
| Miki Takeuchi, Shingo Yamaguchi, Yoshimasa Sakakibara, Takuto Hayashi, Koji Matsuda, Yuichiro Hara, Chiharu Tanegashima, Takashi Shimizu, Shigehiro Kuraku, Masahiko Hib. Gene expression profiling of granule cells and Purkinje cells in the zebrafish cerebellum. The Journal of comparative neurology. vol 525. issue 7. 2017-09-15. PMID:27615194. |
gene expression profiling of granule cells and purkinje cells in the zebrafish cerebellum. |
2017-09-15 |
2023-08-13 |
zebrafish |
| Miki Takeuchi, Shingo Yamaguchi, Yoshimasa Sakakibara, Takuto Hayashi, Koji Matsuda, Yuichiro Hara, Chiharu Tanegashima, Takashi Shimizu, Shigehiro Kuraku, Masahiko Hib. Gene expression profiling of granule cells and Purkinje cells in the zebrafish cerebellum. The Journal of comparative neurology. vol 525. issue 7. 2017-09-15. PMID:27615194. |
this study uses zebrafish transgenic larvae expressing fluorescent proteins in granule cells, purkinje cells, or other cerebellar neurons and glial cells to isolate each type of cerebellar cells by fluorescence-activated cell sorting and to profile their gene expressions by rna sequencing and in situ hybridization. |
2017-09-15 |
2023-08-13 |
zebrafish |
| Stella M K Glasauer, Robert Wäger, Matthias Gesemann, Stephan C F Neuhaus. mglur6b:EGFP Transgenic zebrafish suggest novel functions of metabotropic glutamate signaling in retina and other brain regions. The Journal of comparative neurology. vol 524. issue 12. 2017-09-13. PMID:27121676. |
apart from the retina, we found transgene expression in subsets of periventricular neurons of the hypothalamus, purkinje cells of the cerebellum, various cell types of the optic tectum, and mitral/ruffed cells of the olfactory bulb. |
2017-09-13 |
2023-08-13 |
zebrafish |
| Joe Fenn, Mike Boursnell, Rebekkah J Hitti, Christopher A Jenkins, Rebecca L Terry, Simon L Priestnall, Patrick J Kenny, Cathryn S Mellersh, Oliver P Forma. Genome sequencing reveals a splice donor site mutation in the SNX14 gene associated with a novel cerebellar cortical degeneration in the Hungarian Vizsla dog breed. BMC genetics. vol 17. issue 1. 2017-09-13. PMID:27566131. |
cerebellar histopathological findings typically consist of primary purkinje neuronal degeneration and loss, with variable secondary depletion of the granular and molecular cell layers. |
2017-09-13 |
2023-08-13 |
dog |
| Nidia Quillinan, Guiying Deng, Kaori Shimizu, Ivelisse Cruz-Torres, Christian Schroeder, Richard J Traystman, Paco S Herso. Long-term depression in Purkinje neurons is persistently impaired following cardiac arrest and cardiopulmonary resuscitation in mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 37. issue 8. 2017-09-11. PMID:28168893. |
to determine the effects of ca/cpr on plasticity in the cerebellum, we used whole cell recordings from purkinje neurons to examine long-term depression (ltd) at parallel fiber (pf) synapses. |
2017-09-11 |
2023-08-13 |
mouse |
| Yalan Zhang, Leonard K Kaczmare. Kv3.3 potassium channels and spinocerebellar ataxia. The Journal of physiology. vol 594. issue 16. 2017-08-29. PMID:26442672. |
in the cerebellum, it helps to shape the very characteristic complex spike of purkinje cells. |
2017-08-29 |
2023-08-13 |
human |
| Zhen Yang, Fidel Santamari. Purkinje cell intrinsic excitability increases after synaptic long term depression. Journal of neurophysiology. vol 116. issue 3. 2017-08-28. PMID:27306677. |
we performed whole cell patch-clamp recordings of purkinje cells in sagittal cerebellar slices in mice. |
2017-08-28 |
2023-08-13 |
mouse |