| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daniel R Scoles, Pratap Meera, Matthew D Schneider, Sharan Paul, Warunee Dansithong, Karla P Figueroa, Gene Hung, Frank Rigo, C Frank Bennett, Thomas S Otis, Stefan M Puls. Antisense oligonucleotide therapy for spinocerebellar ataxia type 2. Nature. vol 544. issue 7650. 2017-08-22. PMID:28405024. |
after delivery by intracerebroventricular injection to atxn2-q127 mice, aso7 localized to purkinje cells, reduced cerebellar atxn2 expression below 75% for more than 10 weeks without microglial activation, and reduced the levels of cerebellar atxn2. |
2017-08-22 |
2023-08-13 |
mouse |
| Martha L Streng, Laurentiu S Popa, Timothy J Ebne. Climbing Fibers Control Purkinje Cell Representations of Behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 37. issue 8. 2017-08-18. PMID:28077726. |
a crucial issue in understanding cerebellar function is the interaction between simple spike (ss) and complex spike (cs) discharge, the two fundamentally different activity modalities of purkinje cells. |
2017-08-18 |
2023-08-13 |
monkey |
| Bo Zhang, Thomas C Südho. Neuroligins Are Selectively Essential for NMDAR Signaling in Cerebellar Stellate Interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 35. 2017-08-17. PMID:27581450. |
by crossing triple conditional knock-out (cko) mice targeting all three major neuroligins [neuroligin-1 to neuroligin-3 (nl123)] with parvalbumin-cre (pv-cre) transgenic mice, we deleted neuroligins from inhibitory cerebellar interneurons and purkinje cells, allowing us to study the effects of neuroligin deletions on cerebellar stellate cell synapses by electrophysiology in acute slices. |
2017-08-17 |
2023-08-13 |
mouse |
| Mark J Wagner, Tony Hyun Kim, Joan Savall, Mark J Schnitzer, Liqun Lu. Cerebellar granule cells encode the expectation of reward. Nature. vol 544. issue 7648. 2017-08-17. PMID:28321129. |
the discovery of predictive, non-sensorimotor encoding in granule cells is a major departure from the current understanding of these neurons and markedly enriches the contextual information available to postsynaptic purkinje cells, with important implications for cognitive processing in the cerebellum. |
2017-08-17 |
2023-08-13 |
mouse |
| Suma Priya Sudarsana Devi, James R Howe, Céline Auge. Train stimulation of parallel fibre to Purkinje cell inputs reveals two populations of synaptic responses with different receptor signatures. The Journal of physiology. vol 594. issue 13. 2017-08-14. PMID:27094216. |
purkinje cells of the cerebellum receive ∼180,000 parallel fibre synapses, which have often been viewed as a homogeneous synaptic population and studied using single action potentials. |
2017-08-14 |
2023-08-13 |
rat |
| Suma Priya Sudarsana Devi, James R Howe, Céline Auge. Train stimulation of parallel fibre to Purkinje cell inputs reveals two populations of synaptic responses with different receptor signatures. The Journal of physiology. vol 594. issue 13. 2017-08-14. PMID:27094216. |
here, we used trains of stimuli to study parallel fibre inputs to purkinje cells in rat cerebellar slices. |
2017-08-14 |
2023-08-13 |
rat |
| Pranita Nirgudkar, Devin H Taylor, Yuchio Yanagawa, C Fernando Valenzuel. Ethanol exposure during development reduces GABAergic/glycinergic neuron numbers and lobule volumes in the mouse cerebellar vermis. Neuroscience letters. vol 632. 2017-08-08. PMID:27565053. |
although the effect of developmental ethanol exposure on purkinje and granule cells has been previously characterized, its actions on other cerebellar neuronal populations are not fully understood. |
2017-08-08 |
2023-08-13 |
mouse |
| Pranita Nirgudkar, Devin H Taylor, Yuchio Yanagawa, C Fernando Valenzuel. Ethanol exposure during development reduces GABAergic/glycinergic neuron numbers and lobule volumes in the mouse cerebellar vermis. Neuroscience letters. vol 632. 2017-08-08. PMID:27565053. |
these findings indicate that second and third trimester-equivalent ethanol exposure has a greater impact on purkinje cells than interneurons in the developing cerebellar vermis. |
2017-08-08 |
2023-08-13 |
mouse |
| Nour S Ereka. Cerebellar Purkinje cells die by apoptosis in the shaker mutant rat. Brain research. vol 1657. 2017-08-07. PMID:28040459. |
purkinje neurons were the only cerebellar cells labeled for tunel and immunoreactive to active caspase-3 in the shaker mutant. |
2017-08-07 |
2023-08-13 |
rat |
| Yasmine El-Shamayleh, Yoshiko Kojima, Robijanto Soetedjo, Gregory D Horwit. Selective Optogenetic Control of Purkinje Cells in Monkey Cerebellum. Neuron. vol 95. issue 1. 2017-08-01. PMID:28648497. |
selective optogenetic control of purkinje cells in monkey cerebellum. |
2017-08-01 |
2023-08-13 |
monkey |
| Yasmine El-Shamayleh, Yoshiko Kojima, Robijanto Soetedjo, Gregory D Horwit. Selective Optogenetic Control of Purkinje Cells in Monkey Cerebellum. Neuron. vol 95. issue 1. 2017-08-01. PMID:28648497. |
purkinje cells of the primate cerebellum play critical but poorly understood roles in the execution of coordinated, accurate movements. |
2017-08-01 |
2023-08-13 |
monkey |
| Feng C Zhou, Marisol Resendiz, Chiao-Ling Lo, Yuanyuan Che. Cell-Wide DNA De-Methylation and Re-Methylation of Purkinje Neurons in the Developing Cerebellum. PloS one. vol 11. issue 9. 2017-07-31. PMID:27583369. |
cell-wide dna de-methylation and re-methylation of purkinje neurons in the developing cerebellum. |
2017-07-31 |
2023-08-13 |
Not clear |
| Tristan G Heintz, Richard Eva, James W Fawcet. Regional Regulation of Purkinje Cell Dendritic Spines by Integrins and Eph/Ephrins. PloS one. vol 11. issue 8. 2017-07-27. PMID:27518800. |
climbing fibres and parallel fibres compete for dendritic space on purkinje cells in the cerebellum. |
2017-07-27 |
2023-08-13 |
Not clear |
| Daisuke Hoshino, Susumu Setogawa, Yu Kitaoka, Hiroyuki Masuda, Yuki Tamura, Hideo Hatta, Dai Yanagihar. Exercise-induced expression of monocarboxylate transporter 2 in the cerebellum and its contribution to motor performance. Neuroscience letters. vol 633. 2017-07-27. PMID:27619538. |
purkinje cells in the cerebellum have been shown to have high levels of mct2, suggesting that this protein has a key function in energy metabolism and neuronal activities in these cells. |
2017-07-27 |
2023-08-13 |
mouse |
| Xinmin Liu, Nora Hernandez, Sergey Kisselev, Aris Floratos, Ashley Sawle, Iuliana Ionita-Laza, Ruth Ottman, Elan D Louis, Lorraine N Clar. Identification of candidate genes for familial early-onset essential tremor. European journal of human genetics : EJHG. vol 24. issue 7. 2017-07-26. PMID:26508575. |
these genes are highly expressed in the cerebellum and purkinje cells, and influence function of the gamma-amino butyric acid (gaba)-ergic system. |
2017-07-26 |
2023-08-13 |
Not clear |
| Xinmin Liu, Nora Hernandez, Sergey Kisselev, Aris Floratos, Ashley Sawle, Iuliana Ionita-Laza, Ruth Ottman, Elan D Louis, Lorraine N Clar. Identification of candidate genes for familial early-onset essential tremor. European journal of human genetics : EJHG. vol 24. issue 7. 2017-07-26. PMID:26508575. |
this is in concordance with recent evidence that the pathophysiological process in et involves cerebellar dysfunction and possibly cerebellar degeneration with a reduction in purkinje cells, and a decrease in gaba-ergic tone. |
2017-07-26 |
2023-08-13 |
Not clear |
| Douglas R Wylie, Daniel Hoops, Joel W Aspden, Andrew N Iwaniu. Zebrin II Is Expressed in Sagittal Stripes in the Cerebellum of Dragon Lizards (Ctenophorus sp.). Brain, behavior and evolution. vol 88. issue 3-4. 2017-07-19. PMID:28099952. |
aldolase c, also known as zebrin ii (zii), is a glycolytic enzyme that is expressed in cerebellar purkinje cells of the vertebrate cerebellum. |
2017-07-19 |
2023-08-13 |
Not clear |
| Douglas R Wylie, Daniel Hoops, Joel W Aspden, Andrew N Iwaniu. Zebrin II Is Expressed in Sagittal Stripes in the Cerebellum of Dragon Lizards (Ctenophorus sp.). Brain, behavior and evolution. vol 88. issue 3-4. 2017-07-19. PMID:28099952. |
in the posterior part of the cerebellum, on each side of the midline, there were 3 sagittal stripes consisting of purkinje cells with high zii expression (zii+) alternating with 2 sagittal stripes with weaker zii expression (ziiw). |
2017-07-19 |
2023-08-13 |
Not clear |
| Joaquín Martí, M C Santa-Cruz, Roger Serra, José P Hervá. Hydroxyurea Treatment and Development of the Rat Cerebellum: Effects on the Neurogenetic Profiles and Settled Patterns of Purkinje Cells and Deep Cerebellar Nuclei Neurons. Neurotoxicity research. vol 30. issue 4. 2017-07-18. PMID:27401826. |
hydroxyurea treatment and development of the rat cerebellum: effects on the neurogenetic profiles and settled patterns of purkinje cells and deep cerebellar nuclei neurons. |
2017-07-18 |
2023-08-13 |
rat |
| Valeria Pibiri, Clara Gerosa, Laura Vinci, Gavino Faa, Rossano Amb. Immunoreactivity pattern of calretinin in the developing human cerebellar cortex. Acta histochemica. vol 119. issue 3. 2017-07-13. PMID:28174028. |
our study evidenced a different immunoreactivity for calretinin in purkinje cells and in several cerebellar interneurons at different intrauterine developmental stages. |
2017-07-13 |
2023-08-13 |
human |