| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Isao T Tokuda, Huu Hoang, Mitsuo Kawat. New insights into olivo-cerebellar circuits for learning from a small training sample. Current opinion in neurobiology. vol 46. 2018-06-11. PMID:28841437. |
we hypothesize that a unique closed-loop neural circuit formed by the purkinje cells, the cerebellar deep nucleus and the inferior olive in and around the cerebellum and the highest density of gap junctions, which regulate synchronous activities of the inferior olive nucleus, are computational machinery for learning from a small sample. |
2018-06-11 |
2023-08-13 |
Not clear |
| Masahiko Tanaka, Tomomi Senda, Naohide Hirashim. Expression of the GluA2 subunit of glutamate receptors is required for the normal dendritic differentiation of cerebellar Purkinje cells. Neuroscience letters. vol 657. 2018-05-28. PMID:28774570. |
cerebellar purkinje cells differentiate the most elaborate dendritic trees among neurons in the brain and constitute the principal part of cerebellar neuronal circuitry. |
2018-05-28 |
2023-08-13 |
Not clear |
| Martha L Streng, Laurentiu S Popa, Timothy J Ebne. Climbing fibers predict movement kinematics and performance errors. Journal of neurophysiology. vol 118. issue 3. 2018-05-11. PMID:28701537. |
requisite for understanding cerebellar function is a complete characterization of the signals provided by complex spike (cs) discharge of purkinje cells, the output neurons of the cerebellar cortex. |
2018-05-11 |
2023-08-13 |
monkey |
| Takeyuki Sugawara, Chihiro Hisatsune, Hiroyuki Miyamoto, Naoko Ogawa, Katsuhiko Mikoshib. Regulation of spinogenesis in mature Purkinje cells via mGluR/PKC-mediated phosphorylation of CaMKIIβ. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 26. 2018-05-09. PMID:28607044. |
dendritic spines of purkinje cells form excitatory synapses with parallel fiber terminals, which are the primary sites for cerebellar synaptic plasticity. |
2018-05-09 |
2023-08-13 |
Not clear |
| Jun Ju, Qian Liu, Yang Zhang, Yuanxiu Liu, Mei Jiang, Liguo Zhang, Xuelian He, Chenchen Peng, Tao Zheng, Q Richard Lu, Hedong L. Olig2 regulates Purkinje cell generation in the early developing mouse cerebellum. Scientific reports. vol 6. 2018-04-30. PMID:27469598. |
in the cerebellum, deletion of both olig2 and olig1 results in impaired genesis of purkinje cells (pcs) and pax2(+) interneurons. |
2018-04-30 |
2023-08-13 |
mouse |
| Ramanujan T Raghavan, Stephen G Lisberge. Responses of Purkinje cells in the oculomotor vermis of monkeys during smooth pursuit eye movements and saccades: comparison with floccular complex. Journal of neurophysiology. vol 118. issue 2. 2018-04-24. PMID:28515286. |
our goal was to characterize the responses in the vermis using approaches that would allow direct comparisons with responses of purkinje cells in another cerebellar area for pursuit, the floccular complex. |
2018-04-24 |
2023-08-13 |
monkey |
| V V Yasnetsov, S K Karsanova, Vik V Yasnetsov, Yu V Ivanov, V G Motin, N A Chelnay. ACTION OF NEW 3-HYDROXYPYRIDINE DERIVATIVES WITH ANTI-NAUPATHIA PROPERTIES ON CENTRAL NEURONS. Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine. vol 50. issue 6. 2018-04-23. PMID:29553607. |
investigations of rat's cerebellum sections evidenced that 5 mm of ibkhf-27 inhibited population responses of purkinje cells 95 1 3 %. |
2018-04-23 |
2023-08-13 |
rat |
| V V Yasnetsov, S K Karsanova, Vik V Yasnetsov, Yu V Ivanov, V G Motin, N A Chelnay. ACTION OF NEW 3-HYDROXYPYRIDINE DERIVATIVES WITH ANTI-NAUPATHIA PROPERTIES ON CENTRAL NEURONS. Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine. vol 50. issue 6. 2018-04-23. PMID:29553607. |
it follows that ibkhf-27 nearly entirely inhibits synaptic transmission from cerebellar parallel fibers to purkinje cells, while mk-801 has a similarly strong anti-depression effect that testifies the involvement of the nmda-receptor complex predominantly. |
2018-04-23 |
2023-08-13 |
rat |
| Yeechan Wu, Indira M Rama. Facilitation of mossy fibre-driven spiking in the cerebellar nuclei by the synchrony of inhibition. The Journal of physiology. vol 595. issue 15. 2018-04-19. PMID:28513836. |
large premotor neurons of the cerebellar nuclei (cbn cells) integrate synaptic inhibition from purkinje neurons and synaptic excitation from mossy fibres to generate cerebellar output. |
2018-04-19 |
2023-08-13 |
Not clear |
| James Fraser, Alexandra Essebier, Richard M Gronostajski, Mikael Boden, Brandon J Wainwright, Tracey J Harvey, Michael Pipe. Cell-type-specific expression of NFIX in the developing and adult cerebellum. Brain structure & function. vol 222. issue 5. 2018-04-17. PMID:27878595. |
within the adult cerebellum, nfix displayed a broad expression profile, and was evident within granule cells, bergmann glia, and interneurons, but not within purkinje neurons. |
2018-04-17 |
2023-08-13 |
mouse |
| Masahiko Hibi, Koji Matsuda, Miki Takeuchi, Takashi Shimizu, Yasunori Murakam. Evolutionary mechanisms that generate morphology and neural-circuit diversity of the cerebellum. Development, growth & differentiation. vol 59. issue 4. 2018-04-02. PMID:28470724. |
the vertebrate cerebellum contains glutamatergic granule cells (gcs) and gamma-aminobutyric acid (gaba)ergic purkinje cells (pcs). |
2018-04-02 |
2023-08-13 |
zebrafish |
| František Vože. Cerebellum-from J. E. Purkyně up to Contemporary Research. Cerebellum (London, England). vol 16. issue 3. 2018-03-20. PMID:27858255. |
through experiments by purkinje and his followers, the function of the cerebellum was properly attributed to the precision of motor movements and skills. |
2018-03-20 |
2023-08-13 |
Not clear |
| Yuri Kanamaru, Jianxue Li, Natalie Stewart, Richard L Sidman, Emi Takahash. Cerebellar Pathways in Mouse Model of Purkinje Cell Degeneration Detected by High-Angular Resolution Diffusion Imaging Tractography. Cerebellum (London, England). vol 16. issue 3. 2018-03-20. PMID:28102462. |
in this mr study, we imaged with high-angular resolution diffusion imaging (hardi) abnormal cerebellar cortical structure (gray matter) and myelinated axonal pathways (white matter) of a mouse spontaneous mutation, purkinje cell degeneration (pcd), in which almost all purkinje neurons degenerate, mainly between postnatal days 20 and 35. |
2018-03-20 |
2023-08-13 |
mouse |
| Emma M Perkins, Daumante Suminaite, Yvonne L Clarkson, Sin Kwan Lee, Alastair R Lyndon, Jeffrey D Rothstein, David J A Wyllie, Kohichi Tanaka, Mandy Jackso. Posterior cerebellar Purkinje cells in an SCA5/SPARCA1 mouse model are especially vulnerable to the synergistic effect of loss of β-III spectrin and GLAST. Human molecular genetics. vol 25. issue 20. 2018-02-26. PMID:28173092. |
finally, our results demonstrate that purkinje cells in the posterior cerebellum of β-iii-/- mice are most susceptible to the combined loss of eaat4 and glast, with degeneration of proximal dendrites, the site of climbing fibre innervation, most pronounced. |
2018-02-26 |
2023-08-13 |
mouse |
| Aggeliki Giannakopoulo. Neuronal vacuolation and spinocerebellar degeneration associated with altered neurotransmission. Folia neuropathologica. vol 55. issue 2. 2018-02-23. PMID:28677370. |
in the cerebellum, severe vacuolation of cerebellar nuclei neurons, atrophy of purkinje cells, and diminishing of gabaergic and glutamatergic fibres constitute the most striking lesions. |
2018-02-23 |
2023-08-13 |
human |
| Yasukazu Hozumi, Hiroki Fujiwara, Kenya Kaneko, Satoshi Fujii, Matthew K Topham, Masahiko Watanabe, Kaoru Got. Diacylglycerol kinase ε localizes to subsurface cisterns of cerebellar Purkinje cells. Cell and tissue research. vol 368. issue 3. 2018-02-14. PMID:28191598. |
dgkε was richly expressed in principal neurons of higher brain regions, including pyramidal cells in the hippocampus and neocortex, medium spiny neurons in the striatum and purkinje cells in the cerebellum. |
2018-02-14 |
2023-08-13 |
mouse |
| b' A Aslan, A \\xc4\\xb0kinci, O Ba\\xc5\\x9f, O F S\\xc3\\xb6nmez, H Kaya, E Odac\\xc4\\xb. Long-term exposure to a continuous 900 MHz electromagnetic field disrupts cerebellar morphology in young adult male rats. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 92. issue 5. 2018-02-14. PMID:28506085.' |
we found that exposure to continuous 900 mhz emf for 1 h/day during adolescence can disrupt cerebellar morphology and reduce the number of purkinje cells in adolescent rats. |
2018-02-14 |
2023-08-13 |
rat |
| Rachel Fremont, Ambika Tewari, Chantal Angueyra, Kamran Khodakha. A role for cerebellum in the hereditary dystonia DYT1. eLife. vol 6. 2018-02-12. PMID:28198698. |
abnormal motor symptoms in knockdown animals were associated with irregular cerebellar output caused by changes in the intrinsic activity of both purkinje cells and neurons of the deep cerebellar nuclei. |
2018-02-12 |
2023-08-13 |
mouse |
| Pratap Meera, Stefan Pulst, Thomas Oti. A positive feedback loop linking enhanced mGluR function and basal calcium in spinocerebellar ataxia type 2. eLife. vol 6. 2018-02-12. PMID:28518055. |
metabotropic glutamate receptor 1 (mglur1) function in purkinje neurons (pns) is essential for cerebellar development and for motor learning and altered mglur1 signaling causes ataxia. |
2018-02-12 |
2023-08-13 |
mouse |
| Thomas C Harmon, Uri Magaram, David L McLean, Indira M Rama. Distinct responses of Purkinje neurons and roles of simple spikes during associative motor learning in larval zebrafish. eLife. vol 6. 2018-02-12. PMID:28541889. |
to study cerebellar activity during learning, we made whole-cell recordings from larval zebrafish purkinje cells while monitoring fictive swimming during associative conditioning. |
2018-02-12 |
2023-08-13 |
zebrafish |