| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Antonino Naro, Alessia Bramanti, Antonino Leo, Alfredo Manuli, Francesca Sciarrone, Margherita Russo, Placido Bramanti, Rocco Salvatore Calabr\\xc3\\xb. Effects of cerebellar transcranial alternating current stimulation on motor cortex excitability and motor function. Brain structure & function. vol 222. issue 6. 2018-01-30. PMID:28064346.' |
although the exact cerebellar structures and functions involved in such processes are partially known, purkinje cells (pc) and their surrounding interneuronal networks may play a pivotal role concerning cbi and msi. |
2018-01-30 |
2023-08-13 |
human |
| Etsuko Shimobayashi, Wolfgang Wagner, Josef P Kapfhamme. Carbonic Anhydrase 8 Expression in Purkinje Cells Is Controlled by PKCγ Activity and Regulates Purkinje Cell Dendritic Growth. Molecular neurobiology. vol 53. issue 8. 2018-01-22. PMID:26399641. |
because the transgene is exclusively present in purkinje cells, cerebellar tissue from these mice is an attractive starting material for searching genes which might be interacting with pkcγ in purkinje cells for inducing the stunted dendritic growth. |
2018-01-22 |
2023-08-13 |
mouse |
| M M Hamza, S A Rey, P Hilber, A Arabo, T Collin, D Vaudry, D Bure. Early Disruption of Extracellular Pleiotrophin Distribution Alters Cerebellar Neuronal Circuit Development and Function. Molecular neurobiology. vol 53. issue 8. 2018-01-22. PMID:26399645. |
the elementary circuit implicated in the control of locomotion involves purkinje cells, which receive excitatory inputs from parallel and climbing fibers, and are regulated by cerebellar interneurons. |
2018-01-22 |
2023-08-13 |
mouse |
| M M Hamza, S A Rey, P Hilber, A Arabo, T Collin, D Vaudry, D Bure. Early Disruption of Extracellular Pleiotrophin Distribution Alters Cerebellar Neuronal Circuit Development and Function. Molecular neurobiology. vol 53. issue 8. 2018-01-22. PMID:26399645. |
since purkinje cells are the unique output of the cerebellar cortex, we explored the consequences of their ptn-induced atrophy on the function of the cerebellar neuronal circuit in mice. |
2018-01-22 |
2023-08-13 |
mouse |
| Javad Hami, Saeed Vafaei-Nezhad, Kazem Ghaemi, Akram Sadeghi, Ghasem Ivar, Fatemeh Shojae, Mehran Hossein. Stereological study of the effects of maternal diabetes on cerebellar cortex development in rat. Metabolic brain disease. vol 31. issue 3. 2018-01-12. PMID:26842601. |
moreover, the number of granular and purkinje cells in the cerebellum of diabetic neonates was reduced in comparison with the control group at p7 and p14. |
2018-01-12 |
2023-08-13 |
rat |
| b' Ersan Odac\\xc4\\xb1, Hatice Hanc\\xc4\\xb1, Ay\\xc5\\x9fe \\xc4\\xb0kinci, Osman Fikret S\\xc3\\xb6nmez, Ali Aslan, Arzu \\xc5\\x9eahin, Haydar Kaya, Serdar \\xc3\\x87olako\\xc4\\x9flu, Orhan Ba\\xc5\\x9. Maternal exposure to a continuous 900-MHz electromagnetic field provokes neuronal loss and pathological changes in cerebellum of 32-day-old female rat offspring. Journal of chemical neuroanatomy. vol 75. issue Pt B. 2018-01-10. PMID:26391347.' |
the number of purkinje cells was estimated stereologically, and histopathological evaluations were also performed on cerebellar sections. |
2018-01-10 |
2023-08-13 |
rat |
| b' Ersan Odac\\xc4\\xb1, Hatice Hanc\\xc4\\xb1, Ay\\xc5\\x9fe \\xc4\\xb0kinci, Osman Fikret S\\xc3\\xb6nmez, Ali Aslan, Arzu \\xc5\\x9eahin, Haydar Kaya, Serdar \\xc3\\x87olako\\xc4\\x9flu, Orhan Ba\\xc5\\x9. Maternal exposure to a continuous 900-MHz electromagnetic field provokes neuronal loss and pathological changes in cerebellum of 32-day-old female rat offspring. Journal of chemical neuroanatomy. vol 75. issue Pt B. 2018-01-10. PMID:26391347.' |
in conclusion, our study results show that prenatal exposure to emf affects the development of purkinje cells in the female rat cerebellum and that the consequences of this pathological effect persist after the postnatal period. |
2018-01-10 |
2023-08-13 |
rat |
| Austin Ferro, Emily Carbone, Jenny Zhang, Evan Marzouk, Monica Villegas, Asher Siegel, Donna Nguyen, Thomas Possidente, Jessilyn Hartman, Kailen Polley, Melissa A Ingram, Georgia Berry, Thomas H Reynolds, Bernard Possidente, Kimberley Frederick, Stephen Ives, Sarita Lagalwa. Short-term succinic acid treatment mitigates cerebellar mitochondrial OXPHOS dysfunction, neurodegeneration and ataxia in a Purkinje-specific spinocerebellar ataxia type 1 (SCA1) mouse model. PloS one. vol 12. issue 12. 2017-12-29. PMID:29211771. |
in this study, we investigate the role of mitochondrial oxidative phosphorylation (oxphos) deficits in cerebellar tissue of a purkinje cell-driven spinocerebellar ataxia type 1 (sca1) mouse. |
2017-12-29 |
2023-08-13 |
mouse |
| Myeongjeong Choo, Taisuke Miyazaki, Maya Yamazaki, Meiko Kawamura, Takanobu Nakazawa, Jianling Zhang, Asami Tanimura, Naofumi Uesaka, Masahiko Watanabe, Kenji Sakimura, Masanobu Kan. Retrograde BDNF to TrkB signaling promotes synapse elimination in the developing cerebellum. Nature communications. vol 8. issue 1. 2017-12-12. PMID:28775326. |
purkinje cells (pcs) in the neonatal cerebellum are innervated by multiple climbing fibers (cfs). |
2017-12-12 |
2023-08-13 |
Not clear |
| Yu Miyazaki, Xiaofei Du, Shin-Ichi Muramatsu, Christopher M Gome. An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron. Science translational medicine. vol 8. issue 347. 2017-12-07. PMID:27412786. |
whereas sca6 allele knock-in mice show indistinguishable phenotypes from wild-type littermates, expression of sca6-associated α1act (α1actsca6) driven by a purkinje cell-specific promoter in mice produces slowly progressive ataxia and cerebellar atrophy. |
2017-12-07 |
2023-08-13 |
mouse |
| Marc Ingenwerth, Veronica Estrada, Anna Stahr, Hans Werner Müller, Charlotte von Gal. HSF1-deficiency affects gait coordination and cerebellar calbindin levels. Behavioural brain research. vol 310. 2017-12-01. PMID:27173427. |
immunohistochemical analyses of a cerebellum revealed co-localization of hsf1 and calbindin in purkinje cells. |
2017-12-01 |
2023-08-13 |
mouse |
| Chandreyee Sen, Ashwani Kumar Sharma, Charanjit Singh Randhawa, Kuldip Gupt. Cerebellar Cortical Abiotrophy in Young Labrador-Retrievers. Topics in companion animal medicine. vol 32. issue 1. 2017-12-01. PMID:28750785. |
on histopathologic examination of cerebellum, cerebellar cortical abiotrophy was confirmed with extensive loss of purkinje cells, diminution of granular layer, relative thickening and foliar gliosis in white matter. |
2017-12-01 |
2023-08-13 |
Not clear |
| Maria Christina Sergaki, Carlos F Ibáñe. GFRα1 Regulates Purkinje Cell Migration by Counteracting NCAM Function. Cell reports. vol 18. issue 2. 2017-11-21. PMID:28076782. |
during embryonic development of the cerebellum, purkinje cells (pcs) migrate away from the ventricular zone to form the pc plate. |
2017-11-21 |
2023-08-13 |
Not clear |
| Yoshihito Ishida, Hideshi Kawakami, Hiroyuki Kitajima, Ayaka Nishiyama, Yoshiki Sasai, Haruhisa Inoue, Keiko Mugurum. Vulnerability of Purkinje Cells Generated from Spinocerebellar Ataxia Type 6 Patient-Derived iPSCs. Cell reports. vol 17. issue 6. 2017-11-20. PMID:27806289. |
spinocerebellar ataxia type 6 (sca6) is a dominantly inherited neurodegenerative disease characterized by loss of purkinje cells in the cerebellum. |
2017-11-20 |
2023-08-13 |
Not clear |
| Bruno Benedetti, Ariane Benedetti, Bernhard E Fluche. Loss of the calcium channel β4 subunit impairs parallel fibre volley and Purkinje cell firing in cerebellum of adult ataxic mice. The European journal of neuroscience. vol 43. issue 11. 2017-11-13. PMID:27003325. |
we therefore studied the structure and function of purkinje cells in acute cerebellar slices of the β4 (-/-) ataxic (lethargic) mouse, finding that loss of β4 affected purkinje cell input, morphology and pacemaker activity. |
2017-11-13 |
2023-08-13 |
mouse |
| P E Dickson, J Cairns, D Goldowitz, G Mittlema. Cerebellar contribution to higher and lower order rule learning and cognitive flexibility in mice. Neuroscience. vol 345. 2017-11-09. PMID:27012612. |
we tested lurcher↔wildtype aggregation chimeras which lose 0-100% of cerebellar purkinje cells during development on a touchscreen-mediated attentional set-shifting task to assess the contribution of the cerebellum to higher and lower order rule learning and cognitive flexibility. |
2017-11-09 |
2023-08-13 |
mouse |
| Stacey L Main, Randy J Kulesz. Repeated prenatal exposure to valproic acid results in cerebellar hypoplasia and ataxia. Neuroscience. vol 340. 2017-11-06. PMID:27984183. |
we found that throughout all ten lobules of the cerebellar vermis, purkinje cells were significantly smaller and expression of the calcium binding protein calbindin (cb) was significantly reduced. |
2017-11-06 |
2023-08-13 |
rat |
| Huan Wang, Ruidong Zhang, Shengzhou Zhang, Yongkang Zhou, Xiaobing W. Immunohistochemical Localization of Somatostatin in the Brain of Chinese Alligator Alligator sinensis. Anatomical record (Hoboken, N.J. : 2007). vol 300. issue 3. 2017-11-03. PMID:27615412. |
additionally, they were also detected in purkinje's cellular layer of cerebellum, in the reticularis nucleus and raphe nucleus of medulla oblongata. |
2017-11-03 |
2023-08-13 |
Not clear |
| Anna-Kaisa Anttonen, Anni Laari, Maria Kousi, Yawei J Yang, Tiina Jääskeläinen, Mirja Somer, Eija Siintola, Eveliina Jakkula, Mikko Muona, Saara Tegelberg, Tuula Lönnqvist, Helena Pihko, Leena Valanne, Anders Paetau, Melody P Lun, Johanna Hästbacka, Outi Kopra, Tarja Joensuu, Nicholas Katsanis, Maria K Lehtinen, Jorma J Palvimo, Anna-Elina Lehesjok. ZNHIT3 is defective in PEHO syndrome, a severe encephalopathy with cerebellar granule neuron loss. Brain : a journal of neurology. vol 140. issue 5. 2017-10-30. PMID:28335020. |
immunohistochemical analysis of mouse cerebellar tissue demonstrated znhit3 to be expressed in proliferating granule cell precursors, in proliferating and post-mitotic granule cells, and in purkinje cells. |
2017-10-30 |
2023-08-13 |
mouse |
| Kota Nakamura, Mako Beppu, Kaori Sakai, Hayata Yagyu, Saori Matsumaru, Takao Kohno, Mitsuharu Hattor. The C-terminal region of Reelin is necessary for proper positioning of a subset of Purkinje cells in the postnatal cerebellum. Neuroscience. vol 336. 2017-10-12. PMID:27586054. |
the c-terminal region of reelin is necessary for proper positioning of a subset of purkinje cells in the postnatal cerebellum. |
2017-10-12 |
2023-08-13 |
mouse |