| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yoichiro Shinohara, Toshinori Ohtani, Ayumu Konno, Hirokazu Hira. Viral Vector-Based Evaluation of Regulatory Regions in the Neuron-Specific Enolase (NSE) Promoter in Mouse Cerebellum In Vivo. Cerebellum (London, England). vol 16. issue 5-6. 2018-07-30. PMID:28508170. |
removing region a and/or region b abolished the gfp expression in purkinje cells in most cerebellar lobules, with the expression in interneurons almost unchanged. |
2018-07-30 |
2023-08-13 |
mouse |
| Hong Lin, Jordi Magrane, Elisia M Clark, Sarah M Halawani, Nathan Warren, Amy Rattelle, David R Lync. Early VGLUT1-specific parallel fiber synaptic deficits and dysregulated cerebellar circuit in the KIKO mouse model of Friedreich ataxia. Disease models & mechanisms. vol 10. issue 12. 2018-07-27. PMID:29259026. |
moreover, the parvalbumin levels in cerebellar homogenates and purkinje neurons are significantly reduced, but preserved in other interneurons of the cerebellar molecular layer, suggesting specific parvalbumin dysregulation in purkinje neurons of these mice. |
2018-07-27 |
2023-08-13 |
mouse |
| Shu Wang, Xiuqiang Chen, Weilin Wu, Zhida Chen, Huiping Du, Xingfu Wang, Yu Vincent Fu, Liwen Hu, Jianxin Che. Rapid, label-free identification of cerebellar structures using multiphoton microscopy. Journal of biophotonics. vol 10. issue 12. 2018-07-23. PMID:28464515. |
results show that mpm can reveal the cerebellar vermis, hemispheres, medulla, and ventricle, as well as axon bundles, purkinje cells, capillaries, and the pia mater of the cerebellum. |
2018-07-23 |
2023-08-13 |
rat |
| Jui-Yi Hsieh, Diane M Papazia. In Vivo Analysis of Potassium Channelopathies: Loose Patch Recording of Purkinje Cell Firing in Living, Awake Zebrafish. Methods in molecular biology (Clifton, N.J.). vol 1684. 2018-07-23. PMID:29058196. |
here, we describe a method for extracellular, loose patch electrophysiological recording of electrical activity in cerebellar purkinje cells in living, awake zebrafish, with the goal of investigating pathological mechanisms underlying channelopathies or other diseases that disrupt cerebellar function. |
2018-07-23 |
2023-08-13 |
zebrafish |
| Takayoshi Kobayashi, Durga Sundaram, Kazuaki Nakata, Hiromichi Tsuru. Gray-level co-occurrence matrix analysis of several cell types in mouse brain using resolution-enhanced photothermal microscopy. Journal of biomedical optics. vol 22. issue 3. 2018-07-20. PMID:28290595. |
based on the obtained results, we identified that the most suitable glcm parameter is idm for pyramidal neurons and bgi, granule cells in the dentate gyrus, purkinje cells and granule cells in the cerebellum. |
2018-07-20 |
2023-08-13 |
mouse |
| Jeanne Hsieh, Jen-Wei Liu, Horng-Jyh Harn, Kuo-Wei Hsueh, Karthyayani Rajamani, Yu-Chen Deng, Chih-Min Chia, Woei-Cheang Shyu, Shinn-Zong Lin, Tzyy-Wen Chio. Human Olfactory Ensheathing Cell Transplantation Improves Motor Function in a Mouse Model of Type 3 Spinocerebellar Ataxia. Cell transplantation. vol 26. issue 10. 2018-07-19. PMID:29251109. |
in addition, intracranial hoec transplantation alleviated cerebellar inflammation, prohibited purkinje cells from dying, and enhanced the neuroplasticity of cerebellar purkinje cells. |
2018-07-19 |
2023-08-13 |
mouse |
| Carmen Rubio, Artemio Rosiles-Abonce, Cristina Trejo-Solis, Moises Rubio-Osornio, Cesar Mendoza, Veronica Custodio, Juan C Martinez-Lazcano, Edith Gonzalez, Carlos Pa. Increase Signaling of Wnt/β-Catenin Pathway and Presence of Apoptosis in Cerebellum of Kindled Rats. CNS & neurological disorders drug targets. vol 16. issue 7. 2018-07-18. PMID:28124605. |
the purkinje cells (pc), whose axons target the dentate and interpositus nuclei, form the main cerebellar output to forebrain structures involved in epilepsy. |
2018-07-18 |
2023-08-13 |
human |
| E Y Scott, K D Woolard, C J Finno, M C T Penedo, J D Murra. Variation in MUTYH expression in Arabian horses with Cerebellar Abiotrophy. Brain research. vol 1678. 2018-07-16. PMID:29103988. |
cerebellar abiotrophy (ca) is a neurodegenerative disease in arabian horses affecting the cerebellum, more specifically the purkinje neurons. |
2018-07-16 |
2023-08-13 |
Not clear |
| E Y Scott, K D Woolard, C J Finno, M C T Penedo, J D Murra. Variation in MUTYH expression in Arabian horses with Cerebellar Abiotrophy. Brain research. vol 1678. 2018-07-16. PMID:29103988. |
in addition, ca-affected horses show differential expression of a specific isoform of mutyh as well as different localization in the purkinje and granular neurons of the cerebellum. |
2018-07-16 |
2023-08-13 |
Not clear |
| Judit M Pérez Ortiz, Harry T Or. Spinocerebellar Ataxia Type 1: Molecular Mechanisms of Neurodegeneration and Preclinical Studies. Advances in experimental medicine and biology. vol 1049. 2018-07-09. PMID:29427101. |
spinocerebellar ataxia type 1 (sca1) is an adult-onset, inherited disease that leads to degeneration of purkinje cells of the cerebellum and culminates in death 10-30 years after disease onset. |
2018-07-09 |
2023-08-13 |
mouse |
| Xiaofei Du, Christopher Manuel Gome. Spinocerebellar [corrected] Ataxia Type 6: Molecular Mechanisms and Calcium Channel Genetics. Advances in experimental medicine and biology. vol 1049. 2018-07-09. PMID:29427102. |
pathological findings of sca6 include a diffuse loss of purkinje cells, predominantly in the cerebellar vermis. |
2018-07-09 |
2023-08-13 |
Not clear |
| A Kolicheski, H L Barnes Heller, S Arnold, R D Schnabel, J F Taylor, C A Knox, T Mhlanga-Mutangadura, D P O'Brien, G S Johnson, J Dreyfus, M L Kat. Homozygous PPT1 Splice Donor Mutation in a Cane Corso Dog With Neuronal Ceroid Lipofuscinosis. Journal of veterinary internal medicine. vol 31. issue 1. 2018-07-05. PMID:28008682. |
cerebellar storage material was present in the purkinje cells, granular cell layer, and perinuclear regions of neurons in the deep nuclei. |
2018-07-05 |
2023-08-13 |
dog |
| Ákos Boros, Mihály Albert, Péter Pankovics, Hunor Bíró, Patricia A Pesavento, Tung Gia Phan, Eric Delwart, Gábor Reute. Outbreaks of Neuroinvasive Astrovirus Associated with Encephalomyelitis, Weakness, and Paralysis among Weaned Pigs, Hungary. Emerging infectious diseases. vol 23. issue 12. 2018-06-29. PMID:29148391. |
viral rna was predominantly restricted to neurons, particularly in the brain stem, cerebellum (purkinje cells), and cervical spinal cord. |
2018-06-29 |
2023-08-13 |
Not clear |
| Icilio Cavero, Jean-Michel Guillon, Henry H Holzgref. Reminiscing about Jan Evangelista Purkinje: a pioneer of modern experimental physiology. Advances in physiology education. vol 41. issue 4. 2018-06-26. PMID:29066603. |
purkinje's contributions to physiology were manifold: accurate descriptions of various visual phenomena (e.g., purkinje-sanson images, purkinje phenomenon), discovery of the terminal network of the cardiac conduction system (purkinje fibers), identification of cerebellar neuronal bodies (purkinje cells), formulation of the vertigo law (purkinje's law), discovery of criteria to classify human fingerprints, etc. |
2018-06-26 |
2023-08-13 |
human |
| Frances Y Cheng, Jonathan T Fleming, Chin Chian. Bergmann glial Sonic hedgehog signaling activity is required for proper cerebellar cortical expansion and architecture. Developmental biology. vol 440. issue 2. 2018-06-26. PMID:29792854. |
in the cerebellum, cerebellar granule neuron precursors (cgnps) proliferate in response to purkinje neuron-derived sonic hedgehog (shh) before ultimately exiting the cell cycle and migrating radially along bergmann glial fibers. |
2018-06-26 |
2023-08-13 |
Not clear |
| Encarnación De Miguel, Rosa Álvarez-Oter. Development of the cerebellum in turbot (Psetta maxima): Analysis of cell proliferation and distribution of calcium binding proteins. Journal of chemical neuroanatomy. vol 85. 2018-06-22. PMID:28712785. |
the cerebellum becomes fully differentiated during metamorphosis when parvalbumin and calretinin were detected in purkinje and eurydendroid cells. |
2018-06-22 |
2023-08-13 |
Not clear |
| Xiaojie Liu, Yao Chen, Casey R Vickstrom, Yan Li, Andreu Viader, Benjamin F Cravatt, Qing-Song Li. Coordinated regulation of endocannabinoid-mediated retrograde synaptic suppression in the cerebellum by neuronal and astrocytic monoacylglycerol lipase. Scientific reports. vol 6. 2018-06-21. PMID:27775008. |
using knockout mice in which magl is deleted globally or selectively in neurons or astrocytes, we investigated the relative contribution of neuronal and astrocytic magl to the termination of dse and dsi in purkinje cells (pcs) in cerebellar slices. |
2018-06-21 |
2023-08-13 |
mouse |
| Taisuke Miyazaki, Miwako Yamasaki, Kouichi Hashimoto, Kazuhisa Kohda, Michisuke Yuzaki, Keiko Shimamoto, Kohichi Tanaka, Masanobu Kano, Masahiko Watanab. Glutamate transporter GLAST controls synaptic wrapping by Bergmann glia and ensures proper wiring of Purkinje cells. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 28. 2018-06-13. PMID:28655840. |
here we report that bergmann glia (bg), specialized cerebellar astrocytes that thoroughly enwrap purkinje cells (pcs), are essential for synaptic organization in pcs through the action of the l-glutamate/l-aspartate transporter (glast). |
2018-06-13 |
2023-08-13 |
mouse |
| Jean-Jacques Soghomonian, Kunzhong Zhang, Sujithra Reprakash, Gene J Blat. Decreased parvalbumin mRNA levels in cerebellar Purkinje cells in autism. Autism research : official journal of the International Society for Autism Research. vol 10. issue 11. 2018-06-11. PMID:28707805. |
in view of the documented association between parvalbumin-expressing neurons and autism, the objective of the present study was to determine if parvalbumin gene expression is also altered in purkinje neurons of the cerebellum. |
2018-06-11 |
2023-08-13 |
human |
| Jean-Jacques Soghomonian, Kunzhong Zhang, Sujithra Reprakash, Gene J Blat. Decreased parvalbumin mRNA levels in cerebellar Purkinje cells in autism. Autism research : official journal of the International Society for Autism Research. vol 10. issue 11. 2018-06-11. PMID:28707805. |
radioisotopic in situ hybridization histochemistry was used on human tissue sections from control and asd brains in order to detect and measure parvalbumin mrna levels at the single cell level in purkinje cells of crus ii of the lateral cerebellar hemispheres. |
2018-06-11 |
2023-08-13 |
human |