| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Rusiecki, B Lac. Lhermitte-Duclos disease with neurofibrillary tangles in heterotopic cerebral grey matter. Folia neuropathologica. vol 54. issue 2. 2017-04-13. PMID:27543776. |
lhermitte-duclos disease (ldd), a disorder first described by french physicians lhermitte and duclos in 1920 [25], is a benign, slow growing dysplastic gangliocytoma of the cerebellum, characterized by replacement of the granule cell layer by abnormal granule and purkinje like cells. |
2017-04-13 |
2023-08-13 |
Not clear |
| Miguel Perez-Pouchoulen, Marta Miquel, Paul Saft, Brenda Brug, Rebeca Toledo, Maria Elena Hernandez, Jorge Manz. Prenatal exposure to sodium valproate alters androgen receptor expression in the developing cerebellum in a region and age specific manner in male and female rats. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 53. 2017-03-27. PMID:27423376. |
particularly, vpa reduces the number of purkinje neurons in the rat cerebellum parallel to cerebellar abnormalities found in autism. |
2017-03-27 |
2023-08-13 |
rat |
| T Meraz Medina, Jacinto Bañuelos Pineda, Carmen Cecilia Gómez Rodiles, Salvador Jiménez Vallejo, Ricardo Solís Zamora, Pedro Macedonio García Lópe. Identification of brain areas sensitive to the toxic effects of sparteine. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 69. issue 1. 2017-03-14. PMID:27825754. |
the main brain structures sensitive to sparteine were the cerebral cortex (frontal, fronto-parietal and striate) olfactory and amygdaloid areas, the ventromedial hypothalamic nucleus, the purkinje cells in the cerebellum, and the ca1, ca3 and dentate gyrus regions of the hippocampus. |
2017-03-14 |
2023-08-13 |
rat |
| Erez Eitan, Carmel Braverman, Ailone Tichon, Daniel Gitler, Emmette R Hutchison, Mark P Mattson, Esther Prie. Excitotoxic and Radiation Stress Increase TERT Levels in the Mitochondria and Cytosol of Cerebellar Purkinje Neurons. Cerebellum (London, England). vol 15. issue 4. 2017-03-06. PMID:26374457. |
here, we demonstrate that tert is enriched in purkinje neurons, but not in the granule cells of the adult mouse cerebellum. |
2017-03-06 |
2023-08-13 |
mouse |
| Claudius Luziga, Bui Thi To Nga, Gabriel Mbassa, Yoshimi Yamamot. Cathepsin L coexists with Cytotoxic T-lymphocyte Antigen-2 alpha in distinct regions of the mouse brain. Acta histochemica. vol 118. issue 7. 2017-02-27. PMID:27586811. |
colocalization signals in the mesencephalon were strong in the hypothalamus within supramammillary nucleus and lateroanterior hypothalamic nucleus while in the cerebellum was in the deep white matter, granule cell layer and purkinje neurons but moderately in stellate, and basket cells of cerebellar cortex. |
2017-02-27 |
2023-08-13 |
mouse |
| Anju Shukla, Priyanka Upadhyai, Jhanvi Shah, K Neethukrishna, Stephanie Bielas, K M Girish. Autosomal recessive spinocerebellar ataxia 20: Report of a new patient and review of literature. European journal of medical genetics. vol 60. issue 2. 2017-02-10. PMID:27913285. |
autosomal recessive spinocerebellar ataxia 20 (scar20) is a recently described disorder characterized by intellectual disability, ataxia, coarse facial features, progressive loss of purkinje cells in the cerebellum and often hearing loss and skeletal abnormalities. |
2017-02-10 |
2023-08-13 |
Not clear |
| Chiara Magliaro, Carolina Cocito, Stefano Bagatella, Adalberto Merighi, Arti Ahluwalia, Laura Loss. The number of Purkinje neurons and their topology in the cerebellar vermis of normal and reln haplodeficient mouse. Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. vol 207. 2017-02-07. PMID:26996540. |
the number of purkinje neurons and their topology in the cerebellar vermis of normal and reln haplodeficient mouse. |
2017-02-07 |
2023-08-13 |
mouse |
| Chan Chung, Prasanth Puthanveetil, Daniel S Ory, Andrew P Lieberma. Genetic and pharmacological evidence implicates cathepsins in Niemann-Pick C cerebellar degeneration. Human molecular genetics. vol 25. issue 7. 2017-01-23. PMID:26908626. |
deletion of the encoding cstb gene in npc1-deficient mice resulted in striking deleterious effects, particularly within the cerebellum where diffuse loss of purkinje cells was observed in young mice. |
2017-01-23 |
2023-08-13 |
mouse |
| E Hudry, C Martin, S Gandhi, B György, D I Scheffer, D Mu, S F Merkel, F Mingozzi, Z Fitzpatrick, H Dimant, M Masek, T Ragan, S Tan, A R Brisson, S H Ramirez, B T Hyman, C A Maguir. Exosome-associated AAV vector as a robust and convenient neuroscience tool. Gene therapy. vol 23. issue 4. 2017-01-17. PMID:26836117. |
we demonstrated the utility and robustness of exo-aav-mediated gene delivery by detecting direct gfp fluorescence after systemic injection, allowing three-dimensional reconstruction of transduced purkinje cells in the cerebellum using ex vivo serial two-photon tomography. |
2017-01-17 |
2023-08-13 |
mouse |
| Guy Bouvier, David Higgins, Maria Spolidoro, Damien Carrel, Benjamin Mathieu, Clément Léna, Stéphane Dieudonné, Boris Barbour, Nicolas Brunel, Mariano Casad. Burst-Dependent Bidirectional Plasticity in the Cerebellum Is Driven by Presynaptic NMDA Receptors. Cell reports. vol 15. issue 1. 2016-12-20. PMID:27052175. |
numerous studies have shown that cerebellar function is related to the plasticity at the synapses between parallel fibers and purkinje cells. |
2016-12-20 |
2023-08-13 |
Not clear |
| Iraj Aghaei, Vahid Hajali, Ahmadreza Dehpour, Masoud Haghani, Vahid Sheibani, Mohammad Shaban. Alterations in the intrinsic electrophysiological properties of Purkinje neurons in a rat model of hepatic encephalopathy: Relative preventing effect of PPARγ agonist. Brain research bulletin. vol 121. 2016-12-13. PMID:26704786. |
the effects of pioglitazone on bdl-induced electrophysiological changes of the purkinje cerebellum neurons were evaluated by whole-cell patch clamp recordings. |
2016-12-13 |
2023-08-13 |
rat |
| Qi Tian, James L Smart, Joachim H Clement, Yingming Wang, Alex Derkatch, Harald Schubert, Michael V Danilchik, Daniel L Marks, Lev M Fedoro. RHEB1 expression in embryonic and postnatal mouse. Histochemistry and cell biology. vol 145. issue 5. 2016-12-13. PMID:26708151. |
postnatal mice have broad spatial rheb1 expression in different regions of the cerebral cortex, subcortical regions (including hippocampus), olfactory bulb, medulla oblongata, and cerebellum (particularly in purkinje cells). |
2016-12-13 |
2023-08-13 |
mouse |
| Yukun Yuan, William D Atchiso. Multiple Sources of Ca2+ Contribute to Methylmercury-Induced Increased Frequency of Spontaneous Inhibitory Synaptic Responses in Cerebellar Slices of Rat. Toxicological sciences : an official journal of the Society of Toxicology. vol 150. issue 1. 2016-12-13. PMID:26732885. |
we previously showed that elevated intracellular ca(2+) ([ca(2+)]i) in the molecular layer and granule cells in cerebellar slices is responsible for the initial increases in frequency of spontaneous or miniature inhibitory postsynaptic currents (sipscs or mipscs) of purkinje cells following methylmercury (mehg) treatment. |
2016-12-13 |
2023-08-13 |
rat |
| Yukun Yuan, William D Atchiso. Multiple Sources of Ca2+ Contribute to Methylmercury-Induced Increased Frequency of Spontaneous Inhibitory Synaptic Responses in Cerebellar Slices of Rat. Toxicological sciences : an official journal of the Society of Toxicology. vol 150. issue 1. 2016-12-13. PMID:26732885. |
to identify the contribution of different ca(2+) sources to mehg-induced stimulation of spontaneous gaba release, we examined sipsc or mipsc frequency of purkinje cells in acutely prepared cerebellar slices using whole-cell patch-clamp recording techniques under conditions of lowered [ca(2+)]o, pretreatment with caffeine, cyclopiazonic acid (cpa), thapsigargin or ruthenium red (rr) to deplete ryanodine-sensitive and insensitive intracellular ca(2+) stores or mitochondria, or a combination of lowering [ca(2+)]o and increased bapta buffering. |
2016-12-13 |
2023-08-13 |
rat |
| Miguel Perez-Pouchoulen, Rebeca Toledo, Luis I Garcia, Cesar A Perez-Estudillo, Genaro A Coria-Avila, Maria Elena Hernandez, Porfirio Carrillo, Jorge Manz. Androgen receptors in Purkinje neurons are modulated by systemic testosterone and sexual training in a region-specific manner in the male rat. Physiology & behavior. vol 156. 2016-12-13. PMID:26812590. |
we sought to determine the influence of peripheral hormones on the ar expression in purkinje neurons across cerebellar lobules in the vermis of male rats. |
2016-12-13 |
2023-08-13 |
rat |
| Miguel Perez-Pouchoulen, Rebeca Toledo, Luis I Garcia, Cesar A Perez-Estudillo, Genaro A Coria-Avila, Maria Elena Hernandez, Porfirio Carrillo, Jorge Manz. Androgen receptors in Purkinje neurons are modulated by systemic testosterone and sexual training in a region-specific manner in the male rat. Physiology & behavior. vol 156. 2016-12-13. PMID:26812590. |
first, we found a basal ar expression in purkinje neurons that was higher in the superficial region than the deep region only in cerebellar lobules 2, 4, 5, 7, 8 and 9. |
2016-12-13 |
2023-08-13 |
rat |
| Miguel Perez-Pouchoulen, Rebeca Toledo, Luis I Garcia, Cesar A Perez-Estudillo, Genaro A Coria-Avila, Maria Elena Hernandez, Porfirio Carrillo, Jorge Manz. Androgen receptors in Purkinje neurons are modulated by systemic testosterone and sexual training in a region-specific manner in the male rat. Physiology & behavior. vol 156. 2016-12-13. PMID:26812590. |
however, sexual training did not affect ar expression in purkinje neurons according to their location in any of the cerebellar lobules studied. |
2016-12-13 |
2023-08-13 |
rat |
| Miguel Perez-Pouchoulen, Rebeca Toledo, Luis I Garcia, Cesar A Perez-Estudillo, Genaro A Coria-Avila, Maria Elena Hernandez, Porfirio Carrillo, Jorge Manz. Androgen receptors in Purkinje neurons are modulated by systemic testosterone and sexual training in a region-specific manner in the male rat. Physiology & behavior. vol 156. 2016-12-13. PMID:26812590. |
altogether, our findings indicate that purkinje neurons in the vermis are influenced by systemic testosterone in a region-dependent manner highlighting a link between the cerebellum and gonads in the male rat. |
2016-12-13 |
2023-08-13 |
rat |
| Miguel Perez-Pouchoulen, Rebeca Toledo, Luis I Garcia, Cesar A Perez-Estudillo, Genaro A Coria-Avila, Maria Elena Hernandez, Porfirio Carrillo, Jorge Manz. Androgen receptors in Purkinje neurons are modulated by systemic testosterone and sexual training in a region-specific manner in the male rat. Physiology & behavior. vol 156. 2016-12-13. PMID:26812590. |
the ar function in purkinje neurons may be related to cerebellar plasticity since both estrogen and progesterone receptors, members of the nuclear receptor family, regulate plasticity processes in purkinje neurons. |
2016-12-13 |
2023-08-13 |
rat |
| Keiko Kiyonaga-Endou, Manabu Oshima, Kazuya Sugimoto, Mervyn Thomas, Shigeru Taketani, Masasuke Arak. Localization of Neurensin1 in cerebellar Purkinje cells of the developing chick and its possible function in dendrite formation. Brain research. vol 1635. 2016-12-13. PMID:26826586. |
in the cerebellum, purkinje cells are the only one type of neurons stained for nrsn1. |
2016-12-13 |
2023-08-13 |
mouse |