| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Anzilotti, M Tornincasa, R Gerlini, A Conte, P Brancaccio, O Cuomo, G Bianco, A Fusco, L Annunziato, G Pignataro, G M Pieranton. Genetic ablation of homeodomain-interacting protein kinase 2 selectively induces apoptosis of cerebellar Purkinje cells during adulthood and generates an ataxic-like phenotype. Cell death & disease. vol 6. 2016-09-28. PMID:26633710. |
taken together, these results indicate that hipk2 exerts a relevant role in the survival of cerebellar purkinje cells and that hipk2 genetic ablation generates cerebellar dysfunction compatible with an ataxic-like phenotype. |
2016-09-28 |
2023-08-13 |
mouse |
| L An, J Liu, W W Li, Y J Shi, X H Lin, D M Yu, J B Deng, X Q Re. Distribution of LIM domain kinase 1 in the olfactory bulb, cerebral cortex, hippocampus, and cerebellum of the App/PS+/- mice. Genetics and molecular research : GMR. vol 14. issue 4. 2016-09-15. PMID:26681218. |
our results showed that limk1 was present in the nerve fiber layer and external plexiform layer of the olfactory bulb, as well as in the mitral cells and purkinje cells of the cerebellum in app and ps deficient mice. |
2016-09-15 |
2023-08-13 |
mouse |
| Abd El-Fattah B M El-Beltagy, Amoura M Abou-El-Naga, Dalia M Sabr. Neurotoxicological effects of nicotine on the embryonic development of cerebellar cortex of chick embryo during various stages of incubation. Tissue & cell. vol 47. issue 5. 2016-09-13. PMID:26235253. |
furthermore, at 12th day of incubation, the cerebellar foliation was irregular and the purkinje cells not recognized. |
2016-09-13 |
2023-08-13 |
chicken |
| Abd El-Fattah B M El-Beltagy, Amoura M Abou-El-Naga, Dalia M Sabr. Neurotoxicological effects of nicotine on the embryonic development of cerebellar cortex of chick embryo during various stages of incubation. Tissue & cell. vol 47. issue 5. 2016-09-13. PMID:26235253. |
by 16th day of incubation, the cerebellar foliations were irregular with interrupted cerebellar cortex and irregular arrangement of purkinje cells. |
2016-09-13 |
2023-08-13 |
chicken |
| Y B Kabak, M Sozmen, M Yarim, T Guvenc, M O Karayigit, M Y Gulbaha. Immunohistochemical detection of autophagy-related microtubule-associated protein 1 light chain 3 (LC3) in the cerebellums of dogs naturally infected with canine distemper virus. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 90. issue 8. 2016-09-12. PMID:26179070. |
the cytoplasm of purkinje cells, granular layer cells, motor neurons in large cerebellar ganglia and some neurons in white matter were positive for the lc3 antibody in both the control and cdv-infected dogs. |
2016-09-12 |
2023-08-13 |
Not clear |
| Rosanna Beraldi, Chun-Hung Chan, Christopher S Rogers, Attila D Kovács, David K Meyerholz, Constantin Trantzas, Allyn M Lambertz, Benjamin W Darbro, Krystal L Weber, Katherine A M White, Richard V Rheeden, Michael C Kruer, Brian A Dacken, Xiao-Jun Wang, Bryan T Davis, Judy A Rohret, Jason T Struzynski, Frank A Rohret, Jill M Weimer, David A Pearc. A novel porcine model of ataxia telangiectasia reproduces neurological features and motor deficits of human disease. Human molecular genetics. vol 24. issue 22. 2016-09-12. PMID:26374845. |
the initial characterization of at pigs revealed early cerebellar lesions including loss of purkinje cells (pcs) and altered cytoarchitecture suggesting a developmental etiology for at and could advocate for early therapies for at patients. |
2016-09-12 |
2023-08-13 |
human |
| Winda Ariyani, Toshiharu Iwasaki, Wataru Miyazaki, Erdene Khongorzul, Takahito Nakajima, Satomi Kameo, Hiroshi Koyama, Yoshito Tsushima, Noriyuki Koibuch. Effects of Gadolinium-Based Contrast Agents on Thyroid Hormone Receptor Action and Thyroid Hormone-Induced Cerebellar Purkinje Cell Morphogenesis. Frontiers in endocrinology. vol 7. 2016-09-12. PMID:27617003. |
in cerebellar cultures, the dendrite arborization of purkinje cells induced by 10(-9)m t4 was augmented by low-dose gd-dtpa-bma (10(-7)m) but was suppressed by higher dose (10(-5)m). |
2016-09-12 |
2023-08-13 |
Not clear |
| Jonathan Fleming, Chin Chian. The Purkinje neuron: A central orchestrator of cerebellar neurogenesis. Neurogenesis (Austin, Tex.). vol 2. issue 1. 2016-09-08. PMID:27604220. |
these recent findings advance our understanding of how purkinje neurons function dynamically to oversee completion of a balanced cerebellar circuit. |
2016-09-08 |
2023-08-13 |
Not clear |
| Chiara Cervetto, Daniela Frattaroli, Arianna Venturini, Mario Passalacqua, Mario Nobile, Susanna Alloisio, Carlo Tacchetti, Guido Maura, Luigi Francesco Agnati, Manuela Marcol. Calcium-permeable AMPA receptors trigger vesicular glutamate release from Bergmann gliosomes. Neuropharmacology. vol 99. 2016-08-30. PMID:26260232. |
the findings would add a new role for a well-known bergmann target for glutamate (the ca2+-permeable ampa receptors) and a new actor (the gliotransmitter glutamate) at the cerebellar excitatory synapses onto purkinje cells. |
2016-08-30 |
2023-08-13 |
rat |
| Aikaterini S Papadopoulou, Lutgarde Serneels, Tilmann Achsel, Wim Mandemakers, Zsuzsanna Callaerts-Vegh, James Dooley, Pierre Lau, Torik Ayoubi, Enrico Radaelli, Marco Spinazzi, Melanie Neumann, Sébastien S Hébert, Asli Silahtaroglu, Adrian Liston, Rudi D'Hooge, Markus Glatzel, Bart De Stroope. Deficiency of the miR-29a/b-1 cluster leads to ataxic features and cerebellar alterations in mice. Neurobiology of disease. vol 73. 2016-08-29. PMID:25315682. |
the different members of the mir-29 family are strongly expressed in neurons of the olfactory bulb, the hippocampus and in the purkinje cells of the cerebellum. |
2016-08-29 |
2023-08-13 |
mouse |
| Yi Bessie Liu, Ambika Tewari, Johnny Salameh, Elena Arystarkhova, Thomas G Hampton, Allison Brashear, Laurie J Ozelius, Kamran Khodakhah, Kathleen J Sweadne. A dystonia-like movement disorder with brain and spinal neuronal defects is caused by mutation of the mouse laminin β1 subunit, Lamb1. eLife. vol 4. 2016-08-22. PMID:26705335. |
in accordance, awake recording in the cerebellum detected abnormal output from a circuit of two lamb1-expressing neurons, purkinje cells and their deep cerebellar nucleus targets, during abnormal postures. |
2016-08-22 |
2023-08-13 |
mouse |
| Rachel Fremont, Ambika Tewari, Kamran Khodakha. Aberrant Purkinje cell activity is the cause of dystonia in a shRNA-based mouse model of Rapid Onset Dystonia-Parkinsonism. Neurobiology of disease. vol 82. 2016-08-19. PMID:26093171. |
moreover, while the pharmacologic model suggested that aberrant firing of purkinje cells was the main cause of abnormal cerebellar output, it did not allow the scrutiny of this hypothesis. |
2016-08-19 |
2023-08-13 |
mouse |
| Lena Robra, Vatsala Thirumala. The Intracellular Signaling Molecule Darpp-32 Is a Marker for Principal Neurons in the Cerebellum and Cerebellum-Like Circuits of Zebrafish. Frontiers in neuroanatomy. vol 10. 2016-08-19. PMID:27540357. |
these include purkinje neurons in the cerebellum, type-i neurons in the optic tectum, and crest cells in the medial octavolateralis nucleus (mon). |
2016-08-19 |
2023-08-13 |
zebrafish |
| S M Zimatkin, O A Karniushk. [EXPRESSION OF DOUBLECORTIN AND NeuN IN THE DEVELOPING CEREBELLAR NEURONS IN RAT]. Morfologiia (Saint Petersburg, Russia). vol 149. issue 1. 2016-08-18. PMID:27487661. |
dcx expression was not detected in purkinje cells and in the nucleus interpositus of the cerebellum. |
2016-08-18 |
2023-08-13 |
rat |
| Juliana Redondo, Kevin Kemp, Kelly Hares, Claire Rice, Neil Scolding, Alastair Wilkin. Purkinje Cell Pathology and Loss in Multiple Sclerosis Cerebellum. Brain pathology (Zurich, Switzerland). vol 25. issue 6. 2016-08-10. PMID:25411024. |
we studied pathologic changes occurring within purkinje cells of the cerebellum. |
2016-08-10 |
2023-08-13 |
Not clear |
| Elahe Mirarab Razi, Soraya Ghafari, Mohammad Jafar Golalipou. Effect of Gestational Diabetes on Purkinje and Granule Cells Distribution of the Rat Cerebellum in 21 and 28 days of Postnatal Life. Basic and clinical neuroscience. vol 6. issue 1. 2016-08-09. PMID:27504151. |
effect of gestational diabetes on purkinje and granule cells distribution of the rat cerebellum in 21 and 28 days of postnatal life. |
2016-08-09 |
2023-08-13 |
human |
| Elahe Mirarab Razi, Soraya Ghafari, Mohammad Jafar Golalipou. Effect of Gestational Diabetes on Purkinje and Granule Cells Distribution of the Rat Cerebellum in 21 and 28 days of Postnatal Life. Basic and clinical neuroscience. vol 6. issue 1. 2016-08-09. PMID:27504151. |
this study was done to determine the effect of gestational diabetes on the purkinje and granular cells in the cerebellum of rat offspring. |
2016-08-09 |
2023-08-13 |
human |
| Nico Angliker, Michael Burri, Mariana Zaichuk, Jean-Marc Fritschy, Markus A Rüeg. mTORC1 and mTORC2 have largely distinct functions in Purkinje cells. The European journal of neuroscience. vol 42. issue 8. 2016-08-03. PMID:26296489. |
here, we ablated either mtorc1 or mtorc2 conditionally in purkinje cells of the mouse cerebellum to dissect their role in the development, function and survival of these neurons. |
2016-08-03 |
2023-08-13 |
mouse |
| Yumie Ono, Fumihito Saitow, Shiro Konish. Differential Modulation of GABAA Receptors Underlies Postsynaptic Depolarization- and Purinoceptor-Mediated Enhancement of Cerebellar Inhibitory Transmission: A Non-Stationary Fluctuation Analysis Study. PloS one. vol 11. issue 3. 2016-08-02. PMID:26930485. |
cerebellar gabaergic inhibitory transmission between interneurons and purkinje cells (pcs) undergoes a long-lasting enhancement following different stimulations, such as brief depolarization or activation of purinergic receptors of postsynaptic pcs. |
2016-08-02 |
2023-08-13 |
rat |
| Melissa Ingram, Emily A L Wozniak, Lisa Duvick, Rendong Yang, Paul Bergmann, Robert Carson, Brennon O'Callaghan, Huda Y Zoghbi, Christine Henzler, Harry T Or. Cerebellar Transcriptome Profiles of ATXN1 Transgenic Mice Reveal SCA1 Disease Progression and Protection Pathways. Neuron. vol 89. issue 6. 2016-08-02. PMID:26948890. |
weighted gene coexpression network analysis of the cerebellar expression data revealed two gene networks that significantly correlated with disease and have an expression profile correlating with disease progression in atxn1[82q] purkinje cells. |
2016-08-02 |
2023-08-13 |
mouse |