| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Suteera Vibulyaseck, Yuanjun Luo, Hirofumi Fujita, Arata Oh-Nishi, Hiroko Ohki-Hamazaki, Izumi Sugihar. Compartmentalization of the chick cerebellar cortex based on the link between the striped expression pattern of aldolase C and the topographic olivocerebellar projection. The Journal of comparative neurology. vol 523. issue 13. 2016-05-18. PMID:25732420. |
the avian cerebellum is organized into multiple longitudinal stripes defined by expression profiles of aldolase c (zebrin ii) in purkinje cells. |
2016-05-18 |
2023-08-13 |
chicken |
| Yoshiaki Kita, Kazuto Tanaka, Fujio Murakam. Specific labeling of climbing fibers shows early synaptic interactions with immature Purkinje cells in the prenatal cerebellum. Developmental neurobiology. vol 75. issue 9. 2016-05-17. PMID:25529108. |
specific labeling of climbing fibers shows early synaptic interactions with immature purkinje cells in the prenatal cerebellum. |
2016-05-17 |
2023-08-13 |
mouse |
| Yoshiaki Kita, Kazuto Tanaka, Fujio Murakam. Specific labeling of climbing fibers shows early synaptic interactions with immature Purkinje cells in the prenatal cerebellum. Developmental neurobiology. vol 75. issue 9. 2016-05-17. PMID:25529108. |
however, in the cerebellum climbing fibers (cfs), major afferent axons, arrive near their target neurons, purkinje cells, when the neurons are still actively migrating. |
2016-05-17 |
2023-08-13 |
mouse |
| Yoshiaki Kita, Kazuto Tanaka, Fujio Murakam. Specific labeling of climbing fibers shows early synaptic interactions with immature Purkinje cells in the prenatal cerebellum. Developmental neurobiology. vol 75. issue 9. 2016-05-17. PMID:25529108. |
these observations suggest that cfs form synapses with purkinje cells as soon as the fibers enter the cerebellum. |
2016-05-17 |
2023-08-13 |
mouse |
| Yoonhee Kim, Taegon Kim, Jun Kyu Rhee, Dongwon Lee, Keiko Tanaka-Yamamoto, Yukio Yamamot. Selective transgene expression in cerebellar Purkinje cells and granule cells using adeno-associated viruses together with specific promoters. Brain research. vol 1620. 2016-05-16. PMID:25988836. |
whereas aav with ubiquitous promoters, the cytomegalovirus early enhancer/chicken β-actin promoter, and a small fragment of the synapsin-1 gene promoter caused ubiquitous expression in all cerebellar neurons tested, aav with the camkiiα promoter injected into 10-day-old mice enabled selective expression in purkinje cells. |
2016-05-16 |
2023-08-13 |
mouse |
| Takashi Matsuwaki, Akira Kobayashi, Kanade Mase, Katsuyuki Nakamura, Shin-Ichi Nakano, Takahiro Miyoshi, Keitaro Yamanouchi, Masugi Nishihar. Possible involvement of the cerebellum in motor-function impairment in progranulin-deficient mice. Neuroreport. vol 26. issue 14. 2016-05-16. PMID:26302163. |
previously, we showed that pgrn was expressed broadly in the brain and the purkinje cells in the cerebellum were one of the regions with the highest expression level of pgrn. |
2016-05-16 |
2023-08-13 |
mouse |
| Takashi Matsuwaki, Akira Kobayashi, Kanade Mase, Katsuyuki Nakamura, Shin-Ichi Nakano, Takahiro Miyoshi, Keitaro Yamanouchi, Masugi Nishihar. Possible involvement of the cerebellum in motor-function impairment in progranulin-deficient mice. Neuroreport. vol 26. issue 14. 2016-05-16. PMID:26302163. |
thus, in the present study, we investigated the possible roles of pgrn in the cerebellum by comparing wild-type (wt) and pgrn-deficient (ko) mice with immunohistochemical staining for calbindin, a marker of purkinje cells. |
2016-05-16 |
2023-08-13 |
mouse |
| Takashi Matsuwaki, Akira Kobayashi, Kanade Mase, Katsuyuki Nakamura, Shin-Ichi Nakano, Takahiro Miyoshi, Keitaro Yamanouchi, Masugi Nishihar. Possible involvement of the cerebellum in motor-function impairment in progranulin-deficient mice. Neuroreport. vol 26. issue 14. 2016-05-16. PMID:26302163. |
these results suggest that pgrn is involved in the development and/or maturation of neuronal networks comprising purkinje cells in the cerebellum, which may be a prerequisite to normal motor function. |
2016-05-16 |
2023-08-13 |
mouse |
| Anders S Kristensen, Kasper B Hansen, Peter Naur, Lars Olsen, Natalie L Kurtkaya, Shashank M Dravid, Trine Kvist, Feng Yi, Jacob Pøhlsgaard, Rasmus P Clausen, Michael Gajhede, Jette S Kastrup, Stephen F Trayneli. Pharmacology and Structural Analysis of Ligand Binding to the Orthosteric Site of Glutamate-Like GluD2 Receptors. Molecular pharmacology. vol 89. issue 2. 2016-05-13. PMID:26661043. |
the glud2 receptor is a fundamental component of postsynaptic sites in purkinje neurons, and is required for normal cerebellar function. |
2016-05-13 |
2023-08-13 |
Not clear |
| Liang Zhou, Dong Yang, De-Juan Wang, Ya-Jun Xie, Jia-Huan Zhou, Lin Zhou, Hao Huang, Shuo Han, Chong-Yu Shao, Hua-Shun Li, J Julius Zhu, Meng-Sheng Qiu, Chris I De Zeeuw, Ying She. Numb deficiency in cerebellar Purkinje cells impairs synaptic expression of metabotropic glutamate receptor and motor coordination. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 50. 2016-05-09. PMID:26621723. |
here we show that cerebellar purkinje cells (pcs) express high levels of numb during adulthood and that conditional deletion of numb in pcs is sufficient to impair motor coordination despite maintenance of a normal cerebellar cyto-architecture. |
2016-05-09 |
2023-08-13 |
mouse |
| Sreenivasa R Sankavaram, Mikael A Svensson, Tomas Olsson, Lou Brundin, Clas B Johansso. Cell Fusion along the Anterior-Posterior Neuroaxis in Mice with Experimental Autoimmune Encephalomyelitis. PloS one. vol 10. issue 7. 2016-05-05. PMID:26207625. |
inflammation leads to robust fusion of bone marrow-derived cells with purkinje cells and the formation of binucleate heterokaryons in the cerebellum. |
2016-05-05 |
2023-08-13 |
mouse |
| Dewei Jiang, Ying Zhang, Ronald P Hart, Jianmin Chen, Karl Herrup, Jiali L. Alteration in 5-hydroxymethylcytosine-mediated epigenetic regulation leads to Purkinje cell vulnerability in ATM deficiency. Brain : a journal of neurology. vol 138. issue Pt 12. 2016-05-04. PMID:26510954. |
a long-standing mystery surrounding ataxia-telangiectasia is why it is mainly cerebellar neurons, purkinje cells in particular, that appear vulnerable to atm deficiency. |
2016-05-04 |
2023-08-13 |
mouse |
| Païkan Marcagg. Cerebellar endocannabinoids: retrograde signaling from purkinje cells. Cerebellum (London, England). vol 14. issue 3. 2016-05-02. PMID:25520276. |
cerebellar endocannabinoids: retrograde signaling from purkinje cells. |
2016-05-02 |
2023-08-13 |
Not clear |
| Miki Takeuchi, Shingo Yamaguchi, Shigenobu Yonemura, Kisa Kakiguchi, Yoshikatsu Sato, Tetsuya Higashiyama, Takashi Shimizu, Masahiko Hib. Type IV Collagen Controls the Axogenesis of Cerebellar Granule Cells by Regulating Basement Membrane Integrity in Zebrafish. PLoS genetics. vol 11. issue 10. 2016-04-29. PMID:26451951. |
the axons of the gcs in the caudolateral lobes terminate on crest cells in the dorsal hindbrain, as well as forming en passant synapses with purkinje cells in the cerebellum. |
2016-04-29 |
2023-08-13 |
zebrafish |
| Anna Dulneva, Sheena Lee, Peter L Oliver, Katalin Di Gleria, Benedikt M Kessler, Kay E Davies, Esther B E Becke. The mutant Moonwalker TRPC3 channel links calcium signaling to lipid metabolism in the developing cerebellum. Human molecular genetics. vol 24. issue 14. 2016-04-28. PMID:25908616. |
consistently, lipid homeostasis in the mwk cerebellum was found to be disturbed, and treatment of organotypic cerebellar slices with ceramide significantly improved dendritic outgrowth of mwk purkinje cells. |
2016-04-28 |
2023-08-13 |
mouse |
| David J Herzfeld, Yoshiko Kojima, Robijanto Soetedjo, Reza Shadmeh. Encoding of action by the Purkinje cells of the cerebellum. Nature. vol 526. issue 7573. 2016-04-28. PMID:26469054. |
encoding of action by the purkinje cells of the cerebellum. |
2016-04-28 |
2023-08-13 |
monkey |
| David J Herzfeld, Yoshiko Kojima, Robijanto Soetedjo, Reza Shadmeh. Encoding of action by the Purkinje cells of the cerebellum. Nature. vol 526. issue 7573. 2016-04-28. PMID:26469054. |
execution of accurate eye movements depends critically on the cerebellum, suggesting that the major output neurons of the cerebellum, purkinje cells, may predict motion of the eye. |
2016-04-28 |
2023-08-13 |
monkey |
| David J Herzfeld, Yoshiko Kojima, Robijanto Soetedjo, Reza Shadmeh. Encoding of action by the Purkinje cells of the cerebellum. Nature. vol 526. issue 7573. 2016-04-28. PMID:26469054. |
this suggests that the cerebellum predicts the real-time motion of the eye during saccades via the combined inputs of purkinje cells onto individual nucleus neurons. |
2016-04-28 |
2023-08-13 |
monkey |
| N Grintsova, L Vasko, L Kiptenko, A Gortinsky, N Murenet. [MORPHOFUNCTIONAL ADJUSTMENT VASCULAR AND CELLULAR COMPONENTS OF THE CEREBELLAR CORTEX IN EXPOSURE TO BODY SULFATES OF COPPER, ZINC AND IRON]. Georgian medical news. issue 246. 2016-04-22. PMID:26355321. |
it was found that the combined effect on the body of sulphates of copper and zinc, and iron in the cerebellum has enough expressive toxicity, which affects the condition of the vascular bed, and purkinje cells. |
2016-04-22 |
2023-08-13 |
rat |
| Jing-Ya Wang, I-Shing Yu, Chien-Chi Huang, Chia-Yen Chen, Wan-Ping Wang, Shu-Wha Lin, Kuan-Teh Jeang, Ya-Hui Ch. Sun1 deficiency leads to cerebellar ataxia in mice. Disease models & mechanisms. vol 8. issue 8. 2016-04-19. PMID:26035387. |
our findings reveal a cell-type-specific role for sun1 and sun2 in nucleokinesis during cerebellar development, and we propose the use of sun-deficient mice as a model for studying cerebellar ataxia that is associated with mutation of human syne genes or loss of purkinje cells. |
2016-04-19 |
2023-08-13 |
mouse |