| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Melissa Ingram, Emily A L Wozniak, Lisa Duvick, Rendong Yang, Paul Bergmann, Robert Carson, Brennon O'Callaghan, Huda Y Zoghbi, Christine Henzler, Harry T Or. Cerebellar Transcriptome Profiles of ATXN1 Transgenic Mice Reveal SCA1 Disease Progression and Protection Pathways. Neuron. vol 89. issue 6. 2016-08-02. PMID:26948890. |
the magenta module provides a signature of suppressed transcriptional programs reflecting disease progression in purkinje cells, while the lt yellow module reflects transcriptional programs activated in response to disease in purkinje cells as well as other cerebellar cell types. |
2016-08-02 |
2023-08-13 |
mouse |
| D Prastiwi, A Djunaidi, G Partadiredj. High dosage of monosodium glutamate causes deficits of the motor coordination and the number of cerebellar Purkinje cells of rats. Human & experimental toxicology. vol 34. issue 11. 2016-08-01. PMID:25697849. |
this study aimed at investigating the effects of different doses of msg on the motor coordination and the number of purkinje cells of the cerebellum of wistar rats. |
2016-08-01 |
2023-08-13 |
rat |
| Ryoichi Ichikawa, Kouichi Hashimoto, Taisuke Miyazaki, Motokazu Uchigashima, Miwako Yamasaki, Atsu Aiba, Masanobu Kano, Masahiko Watanab. Territories of heterologous inputs onto Purkinje cell dendrites are segregated by mGluR1-dependent parallel fiber synapse elimination. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 8. 2016-07-25. PMID:26858447. |
in purkinje cells (pcs) of the cerebellum, a single "winner" climbing fiber (cf) monopolizes proximal dendrites, whereas hundreds of thousands of parallel fibers (pfs) innervate distal dendrites, and both cf and pf inputs innervate a narrow intermediate domain. |
2016-07-25 |
2023-08-13 |
mouse |
| Tooka Aavani, Shadna A Rana, Richard Hawkes, Quentin J Pittma. Maternal immune activation produces cerebellar hyperplasia and alterations in motor and social behaviors in male and female mice. Cerebellum (London, England). vol 14. issue 5. 2016-07-22. PMID:25863812. |
when sagittal sections of the cerebellum were immunostained for calbindin and purkinje cell numbers were counted, we observed greater numbers of purkinje cells in poly(i:c) offspring at both p18 and ~ p120. |
2016-07-22 |
2023-08-13 |
mouse |
| Tooka Aavani, Shadna A Rana, Richard Hawkes, Quentin J Pittma. Maternal immune activation produces cerebellar hyperplasia and alterations in motor and social behaviors in male and female mice. Cerebellum (London, England). vol 14. issue 5. 2016-07-22. PMID:25863812. |
our results suggest that maternal immune exposure at a critical time of cerebellum development can enhance neuronal survival or impair normal programmed cell death of purkinje cells, with lasting consequences on cerebellar morphology and a variety of motor and non-motor behaviors. |
2016-07-22 |
2023-08-13 |
mouse |
| Kyla R Hamling, Zachary J C Tobias, Tamily A Weissma. Mapping the development of cerebellar Purkinje cells in zebrafish. Developmental neurobiology. vol 75. issue 11. 2016-07-12. PMID:25655100. |
the functioning of this circuit depends upon purkinje cells and other cerebellar neurons forming in the precise place and time during development. |
2016-07-12 |
2023-08-13 |
zebrafish |
| Kyla R Hamling, Zachary J C Tobias, Tamily A Weissma. Mapping the development of cerebellar Purkinje cells in zebrafish. Developmental neurobiology. vol 75. issue 11. 2016-07-12. PMID:25655100. |
to begin to quantitatively measure cerebellar development in zebrafish, we have characterized the spatial and temporal patterning of purkinje cells during the first 2 weeks of development. |
2016-07-12 |
2023-08-13 |
zebrafish |
| Mohini Sengupta, Vatsala Thirumala. AMPA receptor mediated synaptic excitation drives state-dependent bursting in Purkinje neurons of zebrafish larvae. eLife. vol 4. 2016-06-30. PMID:26416140. |
purkinje neurons are central to cerebellar function and show membrane bistability when recorded in vitro or in vivo under anesthesia. |
2016-06-30 |
2023-08-13 |
zebrafish |
| Isaac A Adedara, Olatunde Owoeye, Motunrayo A Aiyegbusi, Joshua O Dagunduro, Yetunde M Daramola, Ebenezer O Faromb. Kolaviron protects against benzo[a]pyrene-induced functional alterations along the brain-pituitary-gonadal axis in male rats. Environmental toxicology and pharmacology. vol 40. issue 2. 2016-06-29. PMID:26280929. |
light microscopy revealed severe necrosis of the purkinje cells in the cerebellum, neuronal degeneration of the cerebral cortex, neuronal necrosis of the hippocampus and testicular atrophy in b[a]p-treated rats. |
2016-06-29 |
2023-08-13 |
rat |
| Zhenyu Gao, Martina Proietti-Onori, Zhanmin Lin, Michiel M Ten Brinke, Henk-Jan Boele, Jan-Willem Potters, Tom J H Ruigrok, Freek E Hoebeek, Chris I De Zeeu. Excitatory Cerebellar Nucleocortical Circuit Provides Internal Amplification during Associative Conditioning. Neuron. vol 89. issue 3. 2016-06-28. PMID:26844836. |
we find that excitatory output neurons in the interposed nucleus provide efference-copy signals via mossy fibers to the cerebellar cortical zones that belong to the same module, triggering monosynaptic responses in granule and golgi cells and indirectly inhibiting purkinje cells. |
2016-06-28 |
2023-08-13 |
Not clear |
| Eyal Seroussi, Yuval Cinnamon, Sara Yosefi, Olga Genin, Julia Gage Smith, Nima Rafati, Susanne Bornelöv, Leif Andersson, Miriam Friedman-Eina. Identification of the Long-Sought Leptin in Chicken and Duck: Expression Pattern of the Highly GC-Rich Avian leptin Fits an Autocrine/Paracrine Rather Than Endocrine Function. Endocrinology. vol 157. issue 2. 2016-06-21. PMID:26587783. |
in situ hybridization demonstrated expression of lep mrna in granular and purkinje cells of the cerebellum, anterior pituitary, and in embryonic limb buds, somites, and branchial arches, suggesting roles in adult brain control of energy balance and during embryonic development. |
2016-06-21 |
2023-08-13 |
chicken |
| Weiping Zhang, Steffen Schmelzeisen, Daniel Parthier, Stephan Frings, Frank Möhrle. Anoctamin Calcium-Activated Chloride Channels May Modulate Inhibitory Transmission in the Cerebellar Cortex. PloS one. vol 10. issue 11. 2016-06-20. PMID:26558388. |
here we examined the recent finding that a calcium-dependent chloride conductance impacts on gabaergic synaptic inhibition in purkinje cells of the cerebellum. |
2016-06-20 |
2023-08-13 |
Not clear |
| Xinlu Li, Marie Ménade, Guennadi Kozlov, Zheping Hu, Zheng Dai, Peter S McPherson, Bernard Brais, Kalle Gehrin. High-Throughput Screening for Ligands of the HEPN Domain of Sacsin. PloS one. vol 10. issue 9. 2016-06-17. PMID:26366743. |
sacsin is a large protein implicated in the neurodevelopmental and neurodegenerative disease autosomal recessive spastic ataxia of charlevoix-saguenay (arsacs), which features the loss of purkinje neurons in the cerebellum. |
2016-06-17 |
2023-08-13 |
Not clear |
| Dolores Vazquez-Sanroman, Ketty Leto, Miguel Cerezo-Garcia, María Carbo-Gas, Carla Sanchis-Segura, Daniela Carulli, Ferdinando Rossi, Marta Mique. The cerebellum on cocaine: plasticity and metaplasticity. Addiction biology. vol 20. issue 5. 2016-06-01. PMID:25619460. |
in the present study, we investigated the effects of a chronic cocaine treatment on molecular and structural plasticity in the cerebellum, including bdnf, d3 dopamine receptors, Δfosb, the glu2 ampa receptor subunit, structural modifications in purkinje neurons and, finally, the evaluation of perineuronal nets (pnns) in the projection neurons of the medial nucleus, the output of the cerebellar vermis. |
2016-06-01 |
2023-08-13 |
mouse |
| Dolores Vazquez-Sanroman, Ketty Leto, Miguel Cerezo-Garcia, María Carbo-Gas, Carla Sanchis-Segura, Daniela Carulli, Ferdinando Rossi, Marta Mique. The cerebellum on cocaine: plasticity and metaplasticity. Addiction biology. vol 20. issue 5. 2016-06-01. PMID:25619460. |
in the current experimental conditions in which repeated cocaine treatment was followed by a 1-week withdrawal period and a new cocaine challenge, our results showed that cocaine induced a large increase in cerebellar probdnf levels and its expression in purkinje neurons, with the mature bdnf expression remaining unchanged. |
2016-06-01 |
2023-08-13 |
mouse |
| Dolores Vazquez-Sanroman, Ketty Leto, Miguel Cerezo-Garcia, María Carbo-Gas, Carla Sanchis-Segura, Daniela Carulli, Ferdinando Rossi, Marta Mique. The cerebellum on cocaine: plasticity and metaplasticity. Addiction biology. vol 20. issue 5. 2016-06-01. PMID:25619460. |
significant pruning in purkinje dendrite arborization and reduction in the size and density of purkinje boutons contacting deep cerebellar projection neurons accompanied cocaine-dependent increase in probdnf. |
2016-06-01 |
2023-08-13 |
mouse |
| Natsumi Ageta-Ishihara, Maya Yamazaki, Kohtarou Konno, Hisako Nakayama, Manabu Abe, Kenji Hashimoto, Tomoki Nishioka, Kozo Kaibuchi, Satoko Hattori, Tsuyoshi Miyakawa, Kohichi Tanaka, Fathul Huda, Hirokazu Hirai, Kouichi Hashimoto, Masahiko Watanabe, Kenji Sakimura, Makoto Kinoshit. A CDC42EP4/septin-based perisynaptic glial scaffold facilitates glutamate clearance. Nature communications. vol 6. 2016-05-31. PMID:26657011. |
here we show that, in the cerebellum, cdc42ep4 is exclusively expressed in bergmann glia and localizes beneath specific membrane domains enwrapping dendritic spines of purkinje cells. |
2016-05-31 |
2023-08-13 |
mouse |
| Chiara Magliaro, Alejandro L Callara, Giorgio Mattei, Marco Morcinelli, Cristina Viaggi, Francesca Vaglini, Arti Ahluwali. Clarifying CLARITY: Quantitative Optimization of the Diffusion Based Delipidation Protocol for Genetically Labeled Tissue. Frontiers in neuroscience. vol 10. 2016-05-20. PMID:27199642. |
here we describe the approach, illustrating an example of how it can be used to determine the optimum clearing time for 1 mm-thick cerebellar slice from transgenic l7gfp mice, in which purkinje neurons express the gfp (green fluorescent protein) tag. |
2016-05-20 |
2023-08-13 |
mouse |
| Daniela Biechl, Alessandro Dorigo, Reinhard W Köster, Benedikt Grothe, Mario F Wulliman. Eppur Si Muove: Evidence for an External Granular Layer and Possibly Transit Amplification in the Teleostean Cerebellum. Frontiers in neuroanatomy. vol 10. 2016-05-20. PMID:27199681. |
for example, shh expressing purkinje cells act in transit amplification of external granular layer (egl) cells of the developing cerebellum. |
2016-05-20 |
2023-08-13 |
zebrafish |
| Daniela Biechl, Alessandro Dorigo, Reinhard W Köster, Benedikt Grothe, Mario F Wulliman. Eppur Si Muove: Evidence for an External Granular Layer and Possibly Transit Amplification in the Teleostean Cerebellum. Frontiers in neuroanatomy. vol 10. 2016-05-20. PMID:27199681. |
analysis of critical cerebellar cell markers on this transgenic background and a ph3 assay for mitotic cells reveals that purkinje cells and eurydendroid cells are completely non-overlapping postmitotic cell populations. |
2016-05-20 |
2023-08-13 |
zebrafish |