| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stefanie Besser, Marit Sicker, Grit Marx, Ulrike Winkler, Volker Eulenburg, Swen Hülsmann, Johannes Hirrlinge. A Transgenic Mouse Line Expressing the Red Fluorescent Protein tdTomato in GABAergic Neurons. PloS one. vol 10. issue 6. 2016-04-19. PMID:26076353. |
robust expression was also observed in cortical and hippocampal neurons, purkinje cells in the cerebellum, amacrine cells in the retina as well as in cells migrating along the rostral migratory stream. |
2016-04-19 |
2023-08-13 |
mouse |
| Marilyn McKasson, Stacey L Clardy, Susan A Clawson, Kenneth E Hill, Blair Wood, Noel Carlson, Mark Bromberg, John E Greenle. Voltage-gated calcium channel autoimmune cerebellar degeneration: Case and study of cytotoxicity. Neurology(R) neuroimmunology & neuroinflammation. vol 3. issue 3. 2016-04-18. PMID:27088118. |
to describe response to treatment in a patient with autoantibodies against voltage-gated calcium channels (vgccs) who presented with autoimmune cerebellar degeneration and subsequently developed lambert-eaton myasthenic syndrome (lems), and to study the effect of the patient's autoantibodies on purkinje cells in rat cerebellar slice cultures. |
2016-04-18 |
2023-08-13 |
rat |
| Kate Powell, Alexandre Mathy, Ian Duguid, Michael Häusse. Synaptic representation of locomotion in single cerebellar granule cells. eLife. vol 4. 2016-04-14. PMID:26083712. |
surprisingly, the entire step sequence can be predicted from input epscs and output spikes of a single granule cell, suggesting that a robust gait code is present already at the cerebellar input layer and transmitted via the granule cell pathway to downstream purkinje cells. |
2016-04-14 |
2023-08-13 |
Not clear |
| Xuejing Wang, Mingming Ma, Junfang Teng, Jiewen Zhang, Shuang Zhou, Ying Zhang, Erxi Wu, Xuebing Din. Chronic exposure to cerebrospinal fluid of multiple system atrophy in neuroblastoma and glioblastoma cells induces cytotoxicity via ER stress and autophagy activation. Oncotarget. vol 6. issue 15. 2016-04-07. PMID:25965819. |
specifically, dopamine neurons in substantia nigra and purkinje cells in cerebellum cortex were degenerated in msa-csf-injected mice. |
2016-04-07 |
2023-08-13 |
mouse |
| Shyam Kumar Sudhakar, Benjamin Torben-Nielsen, Erik De Schutte. Cerebellar Nuclear Neurons Use Time and Rate Coding to Transmit Purkinje Neuron Pauses. PLoS computational biology. vol 11. issue 12. 2016-04-06. PMID:26630202. |
within the cerebellum their direct upstream connections originate from inhibitory purkinje neurons. |
2016-04-06 |
2023-08-13 |
Not clear |
| Christian Rössert, Paul Dean, John Porril. At the Edge of Chaos: How Cerebellar Granular Layer Network Dynamics Can Provide the Basis for Temporal Filters. PLoS computational biology. vol 11. issue 10. 2016-03-30. PMID:26484859. |
models of the cerebellar microcircuit often assume that input signals from the mossy-fibers are expanded and recoded to provide a foundation from which the purkinje cells can synthesize output filters to implement specific input-signal transformations. |
2016-03-30 |
2023-08-13 |
Not clear |
| Kenji Ishibashi, Yoshiharu Miura, Kinya Ishikawa, Kenji Ishii, Kiichi Ishiwat. Decreased metabotropic glutamate receptor type 1 availability in a patient with spinocerebellar ataxia type 6: A (11)C-ITMM PET study. Journal of the neurological sciences. vol 355. issue 1-2. 2016-03-28. PMID:26055313. |
imaging of metabotropic glutamate receptor type 1 (mglur1), localized exclusively in the cerebellar purkinje cells and related to cerebellar function, has recently become possible using positron emission tomography (pet). |
2016-03-28 |
2023-08-13 |
Not clear |
| Marianna E Jun. Alcohol Withdrawal and Cerebellar Mitochondria. Cerebellum (London, England). vol 14. issue 4. 2016-03-24. PMID:25195804. |
this is particularly relevant to the cerebellar neuronal network as glutamate signals are projected to purkinje neurons through granular cells that are the most populated neuronal type in cns. |
2016-03-24 |
2023-08-13 |
human |
| Tomohiko Irie, Ruri Kikura-Hanajiri, Makoto Usami, Nahoko Uchiyama, Yukihiro Goda, Yuko Sekin. MAM-2201, a synthetic cannabinoid drug of abuse, suppresses the synaptic input to cerebellar Purkinje cells via activation of presynaptic CB1 receptors. Neuropharmacology. vol 95. 2016-03-24. PMID:25747605. |
in whole-cell patch-clamp recordings made from purkinje cells (pcs) in slice preparations of the mouse cerebellum, we also found that mam-2201 inhibited glutamate release at parallel fiber-pc synapses via activation of presynaptic cb1rs. |
2016-03-24 |
2023-08-13 |
mouse |
| Pablo M Blazquez, Tatyana A Yakushev. GABA-A Inhibition Shapes the Spatial and Temporal Response Properties of Purkinje Cells in the Macaque Cerebellum. Cell reports. vol 11. issue 7. 2016-03-22. PMID:25959822. |
gaba-a inhibition shapes the spatial and temporal response properties of purkinje cells in the macaque cerebellum. |
2016-03-22 |
2023-08-13 |
monkey |
| Jinkyung Kim, Tae-Ju Park, Namseop Kwon, Dongmyeong Lee, Seunghwan Kim, Yoshiki Kohmura, Tetsuya Ishikawa, Kyong-Tai Kim, Tom Curran, Jung Ho J. Dendritic planarity of Purkinje cells is independent of Reelin signaling. Brain structure & function. vol 220. issue 4. 2016-03-18. PMID:24828132. |
the dendritic planarity of purkinje cells is critical for cerebellar circuit formation. |
2016-03-18 |
2023-08-13 |
Not clear |
| Jinkyung Kim, Tae-Ju Park, Namseop Kwon, Dongmyeong Lee, Seunghwan Kim, Yoshiki Kohmura, Tetsuya Ishikawa, Kyong-Tai Kim, Tom Curran, Jung Ho J. Dendritic planarity of Purkinje cells is independent of Reelin signaling. Brain structure & function. vol 220. issue 4. 2016-03-18. PMID:24828132. |
these results indicate that, during cerebellar formation, purkinje cells migrate into an environment that supports development of dendritic planarity and spine formation. |
2016-03-18 |
2023-08-13 |
Not clear |
| Andreia Barateiro, Shujuan Chen, Mei-Fei Yueh, Adelaide Fernandes, Helena Sofia Domingues, João Relvas, Olivier Barbier, Nghia Nguyen, Robert H Tukey, Dora Brite. Reduced Myelination and Increased Glia Reactivity Resulting from Severe Neonatal Hyperbilirubinemia. Molecular pharmacology. vol 89. issue 1. 2016-03-14. PMID:26480925. |
interestingly, cerebellum was the area most affected, with greater myelination impairment and glia burden, and showing a marked loss of purkinje cells and reduced arborization of the remaining ones. |
2016-03-14 |
2023-08-13 |
mouse |
| Shogo Ohmae, Javier F Medin. Climbing fibers encode a temporal-difference prediction error during cerebellar learning in mice. Nature neuroscience. vol 18. issue 12. 2016-03-14. PMID:26551541. |
climbing fiber inputs to purkinje cells are thought to be involved in generating the instructive signals that drive cerebellar learning. |
2016-03-14 |
2023-08-13 |
mouse |
| Niceto R Luque, Jesús A Garrido, Francisco Naveros, Richard R Carrillo, Egidio D'Angelo, Eduardo Ro. Distributed Cerebellar Motor Learning: A Spike-Timing-Dependent Plasticity Model. Frontiers in computational neuroscience. vol 10. 2016-03-14. PMID:26973504. |
we show that distributed spike-timing-dependent plasticity mechanisms (stdp) located at different cerebellar sites (parallel fibers to purkinje cells, mossy fibers to deep cerebellar nucleus cells, and purkinje cells to deep cerebellar nucleus cells) in close-loop simulations provide an explanation for the complex learning properties of the cerebellum in motor learning. |
2016-03-14 |
2023-08-13 |
Not clear |
| Niceto R Luque, Jesús A Garrido, Francisco Naveros, Richard R Carrillo, Egidio D'Angelo, Eduardo Ro. Distributed Cerebellar Motor Learning: A Spike-Timing-Dependent Plasticity Model. Frontiers in computational neuroscience. vol 10. 2016-03-14. PMID:26973504. |
equipping the cerebellum with excitatory (e-stdp) and inhibitory (i-stdp) mechanisms at deep cerebellar nuclei afferents allows the accommodation of synaptic memories that were formed at parallel fibers to purkinje cells synapses and then transferred to mossy fibers to deep cerebellar nucleus synapses. |
2016-03-14 |
2023-08-13 |
Not clear |
| Fanny Jaudon, Fabrice Raynaud, Rosine Wehrlé, Jean-Michel Bellanger, Mohamed Doulazmi, Guilan Vodjdani, Stéphane Gasman, Laurent Fagni, Isabelle Dusart, Anne Debant, Susanne Schmid. The RhoGEF DOCK10 is essential for dendritic spine morphogenesis. Molecular biology of the cell. vol 26. issue 11. 2016-03-08. PMID:25851601. |
purkinje cells (pcs) of the cerebellum, by developing spectacular dendrites covered with spines, represent an attractive model system in which to decipher the molecular signaling underlying these processes. |
2016-03-08 |
2023-08-13 |
mouse |
| Dongwon Lee, Yukio Yamamoto, Eunjoon Kim, Keiko Tanaka-Yamamot. Functional and Physical Interaction of Diacylglycerol Kinase ζ with Protein Kinase Cα Is Required for Cerebellar Long-Term Depression. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 46. 2016-02-29. PMID:26586831. |
protein kinase cα (pkcα) is a major mediator that triggers long-term depression (ltd) at synapses between parallel fibers and purkinje cells in the cerebellum. |
2016-02-29 |
2023-08-13 |
mouse |
| Eiji Mizutani, Mami Oikawa, Hidetoshi Kassai, Kimiko Inoue, Hirosuke Shiura, Ryutaro Hirasawa, Satoshi Kamimura, Shogo Matoba, Narumi Ogonuki, Hiroaki Nagatomo, Kuniya Abe, Teruhiko Wakayama, Atsu Aiba, Atsuo Ogur. Generation of cloned mice from adult neurons by direct nuclear transfer. Biology of reproduction. vol 92. issue 3. 2016-02-22. PMID:25653280. |
first, we used a specific antibody to discover cell types with reduced amounts of a repressive histone mark-dimethylated histone h3 lysine 9 (h3k9me2)-and identified ca1 pyramidal cells in the hippocampus and purkinje cells in the cerebellum as candidates. |
2016-02-22 |
2023-08-13 |
mouse |
| Hiroaki Miyahara, Tomoyo Itonaga, Tomoki Maeda, Tatsuro Izumi, Kenji Ihar. Overexpression of p53 but not Rb in the cytoplasm of neurons and small vessels in an autopsy of a patient with Cockayne syndrome. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 35. issue 3. 2016-02-19. PMID:25495205. |
neuropathological findings in this case revealed basal ganglia calcification, tigroid leukodystrophy, bizarre reactive astrocytes, severe cerebellar atrophy with loss of purkinje cells, and arteriolar/neuronal calcifications in the hypothalamus. |
2016-02-19 |
2023-08-13 |
Not clear |