| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I. Torres-Aleman, S. Pons, F. F. Santos-Benit. Survival of Purkinje Cells in Cerebellar Cultures is Increased by Insulin-like Growth Factor I. The European journal of neuroscience. vol 4. issue 9. 2019-11-20. PMID:12106309. |
addition of igf-i to rat cerebellar cultures produced a 7-fold increase in the number of purkinje cells (calbindin-positive) together with an increase in the calbindin content of the cultures. |
2019-11-20 |
2023-08-12 |
rat |
| J. A. Armengol, A. López-Romá. Left Unilateral Inferior Pedunculotomy Prevents Neuronal Death During Postnatal Development of the Remaining Left Inferior Olivary Complex in the Rat. The European journal of neuroscience. vol 4. issue 7. 2019-11-20. PMID:12106327. |
purkinje cells) that is theoretically provided by sectioning one inferior cerebellar peduncle to the developing climbing fibres of the remaining ioc could prevent the loss of inferior olivary neurons taking place during the first 2 weeks of postnatal life in the rat. |
2019-11-20 |
2023-08-12 |
rat |
| Ferdinando Rossi, Tiziana Borsello, Piergiorgio Strat. Embryonic Purkinje Cells Grafted on the Surface of the Cerebellar Cortex Integrate in the Adult Unlesioned Cerebellum. The European journal of neuroscience. vol 4. issue 6. 2019-11-20. PMID:12106344. |
embryonic purkinje cells grafted on the surface of the cerebellar cortex integrate in the adult unlesioned cerebellum. |
2019-11-20 |
2023-08-12 |
rat |
| Ferdinando Rossi, Tiziana Borsello, Piergiorgio Strat. Embryonic Purkinje Cells Grafted on the Surface of the Cerebellar Cortex Integrate in the Adult Unlesioned Cerebellum. The European journal of neuroscience. vol 4. issue 6. 2019-11-20. PMID:12106344. |
in the present study we have placed solid grafts of cerebellar anlage in the fourth ventricle of adult rats, in close contact with the host cerebellar cortex, to assess the capacity of embryonic purkinje cells to interact with adult neurons and integrate in the unlesioned cerebellar cortex. |
2019-11-20 |
2023-08-12 |
rat |
| Ferdinando Rossi, Tiziana Borsello, Piergiorgio Strat. Embryonic Purkinje Cells Grafted on the Surface of the Cerebellar Cortex Integrate in the Adult Unlesioned Cerebellum. The European journal of neuroscience. vol 4. issue 6. 2019-11-20. PMID:12106344. |
climbing fibre collateral branches also penetrate the implant to innervate purkinje cells which have not migrated in the host cerebellum. |
2019-11-20 |
2023-08-12 |
rat |
| F. Frederic, F. Hainaut, M. Thomasset, J. L. Guenet, N. Delhaye-Bouchaud, J. Marian. Cell Counts of Purkinje and Inferior Olivary Neurons in the 'Hyperspiny Purkinje Cells' Mutant Mouse. The European journal of neuroscience. vol 4. issue 2. 2019-11-20. PMID:12106375. |
the mutant mouse 'hyperspiny purkinje cells' (hpc) has morphologically abnormal purkinje cells and below normal intracerebellar calbindin-d28k, a calcium-binding protein that, in the cerebellum, is found only in the purkinje cells. |
2019-11-20 |
2023-08-12 |
mouse |
| F. Frederic, F. Hainaut, M. Thomasset, J. L. Guenet, N. Delhaye-Bouchaud, J. Marian. Cell Counts of Purkinje and Inferior Olivary Neurons in the 'Hyperspiny Purkinje Cells' Mutant Mouse. The European journal of neuroscience. vol 4. issue 2. 2019-11-20. PMID:12106375. |
we counted the purkinje cells on serial sections stained with thionin or labelled with anti-calbindin-d28k antibodies to investigate whether the depletion of the cerebellar content of calbindin-d28k was correlated with a reduced number of purkinje cells. |
2019-11-20 |
2023-08-12 |
mouse |
| F. Frederic, F. Hainaut, M. Thomasset, J. L. Guenet, N. Delhaye-Bouchaud, J. Marian. Cell Counts of Purkinje and Inferior Olivary Neurons in the 'Hyperspiny Purkinje Cells' Mutant Mouse. The European journal of neuroscience. vol 4. issue 2. 2019-11-20. PMID:12106375. |
these data suggest that the depleted cerebellar calbindin-d28k content could be explained both by the loss of some purkinje cells and the reduced size of the remaining ones. |
2019-11-20 |
2023-08-12 |
mouse |
| Andrew M. Batchelor, John Garthwait. GABAB Receptors in the Parallel Fibre Pathway of Rat Cerebellum. The European journal of neuroscience. vol 4. issue 11. 2019-11-20. PMID:12106411. |
in order to elucidate the function of these receptors we have recorded from purkinje cells in biplanar slices of immature (14-day-old) and adult rat cerebellum using a low-noise, non-invasive, gap technique. |
2019-11-20 |
2023-08-12 |
rat |
| Alain Chedotal, Constantino Sotel. Early Development of Olivocerebellar Projections in the Fetal Rat Using CGRP Immunocytochemistry. The European journal of neuroscience. vol 4. issue 11. 2019-11-20. PMID:12106421. |
(ii) in the presence of a large spectrum of choices at the surface of the rostral half of the cerebellar plate the labelled olivary axons begin to enter the cerebellum at a precise medial point to abut a region composed solely of migrating purkinje cells, and establish contacts with their targets before these neurons reach their final cortical location. |
2019-11-20 |
2023-08-12 |
rat |
| Alain Chedotal, Constantino Sotel. Early Development of Olivocerebellar Projections in the Fetal Rat Using CGRP Immunocytochemistry. The European journal of neuroscience. vol 4. issue 11. 2019-11-20. PMID:12106421. |
(iv) both the early and the late appearing labelled stripes remain confined from the time of their formation in precise cerebellar territories, indicating that only some clusters of purkinje cells are contacted by the cgrp fibres. |
2019-11-20 |
2023-08-12 |
rat |
| Alain Chedotal, Constantino Sotel. Early Development of Olivocerebellar Projections in the Fetal Rat Using CGRP Immunocytochemistry. The European journal of neuroscience. vol 4. issue 11. 2019-11-20. PMID:12106421. |
this absence of chaotic cerebellar invasion, and the high selectivity of the entry points, suggest that the orientation of cgrp-positive olivocerebellar fibres towards their targets is regulated by positional information shared between subsets of olivary neurons and clusters of purkinje cells. |
2019-11-20 |
2023-08-12 |
rat |
| Brigitte Hamon, Françoise Condé, Danielle Jaillard, Monique Thomasset, Francis Crépe. In Vitro Development of Rat Cerebellar Neurons of Early Embryonic Origin. An Anatomical and Electrophysiological Study. The European journal of neuroscience. vol 3. issue 9. 2019-11-20. PMID:12106452. |
the development of the major morphological and electrophysiological properties of presumptive purkinje cells (pcs) was studied in primary cultures of rat cerebellum dissociated on the 14th embryonic day, when pcs are minimally differentiated and migrate in vivo. |
2019-11-20 |
2023-08-12 |
rat |
| Giti Garthwaite, John Garthwait. AMPA Neurotoxicity in Rat Cerebellar and Hippocampal Slices: Histological Evidence for Three Mechanisms. The European journal of neuroscience. vol 3. issue 8. 2019-11-20. PMID:12106458. |
in cerebellar slices, ampa induced the degeneration of most purkinje cells together with a population of golgi cells; in hippocampal slices the neurons were affected in the order ca3 > ca1 > dentate granule cells. |
2019-11-20 |
2023-08-12 |
rat |
| Esther Krook-Magnuson, Gergely G Szabo, Caren Armstrong, Mikko Oijala, Ivan Soltes. Cerebellar Directed Optogenetic Intervention Inhibits Spontaneous Hippocampal Seizures in a Mouse Model of Temporal Lobe Epilepsy. eNeuro. vol 1. issue 1. 2019-11-20. PMID:25599088. |
specifically, on-demand optogenetic excitation or inhibition of parvalbumin-expressing neurons, including purkinje cells, in the lateral or midline cerebellum results in a decrease in seizure duration. |
2019-11-20 |
2023-08-13 |
mouse |
| Matthieu M Vermeren, Qifeng Zhang, Elizabeth Smethurst, Anne Segonds-Pichon, Heinrich Schrewe, Michael J O Wakela. The Phospholipase D2 Knock Out Mouse Has Ectopic Purkinje Cells and Suffers from Early Adult-Onset Anosmia. PloS one. vol 11. issue 9. 2019-11-20. PMID:27658289. |
the expression pattern lead us to specifically examine the mitral cells of olfactory bulbs, the cornus amonis (ca) regions of the hippocampus and the purkinje cells of the cerebellum. |
2019-11-20 |
2023-08-13 |
mouse |
| Matthieu M Vermeren, Qifeng Zhang, Elizabeth Smethurst, Anne Segonds-Pichon, Heinrich Schrewe, Michael J O Wakela. The Phospholipase D2 Knock Out Mouse Has Ectopic Purkinje Cells and Suffers from Early Adult-Onset Anosmia. PloS one. vol 11. issue 9. 2019-11-20. PMID:27658289. |
we find that the change to longer pa species correlates with subtle architectural defect in the cerebellum, exemplified by ectopic purkinje cells and an adult-onset deficit of olfaction. |
2019-11-20 |
2023-08-13 |
mouse |
| Masanobu Kano, Takaki Watanab. Type-1 metabotropic glutamate receptor signaling in cerebellar Purkinje cells in health and disease. F1000Research. vol 6. 2019-11-20. PMID:28435670. |
purkinje cells are the sole output neurons from the cerebellar cortex and therefore play crucial roles in the overall function of the cerebellum. |
2019-11-20 |
2023-08-13 |
mouse |
| Masanobu Kano, Takaki Watanab. Type-1 metabotropic glutamate receptor signaling in cerebellar Purkinje cells in health and disease. F1000Research. vol 6. 2019-11-20. PMID:28435670. |
we also describe emerging evidence that altered mglur1 signaling in purkinje cells underlies cerebellar dysfunctions in several clinically relevant mouse models of human ataxias. |
2019-11-20 |
2023-08-13 |
mouse |
| Sandra A Acosta, Sherwin Mashkouri, Diana Nwokoye, Jea Y Lee, Cesar V Borlonga. Chronic inflammation and apoptosis propagate in ischemic cerebellum and heart of non-human primates. Oncotarget. vol 8. issue 61. 2019-11-20. PMID:29262526. |
unbiased stereological analyses of immunostained tissues showed significant purkinje cells loss in lobule iii and lobule ix of the tgi cerebellum relative to sham cerebellum, with corresponding upregulation of inflammatory and apoptotic cells. |
2019-11-20 |
2023-08-13 |
Not clear |