| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Rodrigo Muñoz-Castañeda, David Díaz, Leticia Peris, Annie Andrieux, Christophe Bosc, José M Muñoz-Castañeda, Carsten Janke, José R Alonso, Marie-Jo Moutin, Eduardo Weruag. Cytoskeleton stability is essential for the integrity of the cerebellum and its motor- and affective-related behaviors. Scientific reports. vol 8. issue 1. 2019-08-12. PMID:29449678. |
we demonstrate that the lack of ccp1 affects microtubule dynamics and flexibility, defects that contribute to the morphological alterations of the purkinje cells (pcs), and to progressive cerebellar breakdown. |
2019-08-12 |
2023-08-13 |
mouse |
| Neil P M Todd, Sendhil Govender, James G Colebatc. Vestibular cerebellar evoked potentials in humans and their modulation during optokinetic stimulation. Journal of neurophysiology. vol 120. issue 6. 2019-08-02. PMID:30332322. |
we suggest that the eps measured over the posterior fossa are a manifestation of climbing fiber responses of cerebellar cortical purkinje cells, i.e., a form of vestibular cerebellar ep (vscep). |
2019-08-02 |
2023-08-13 |
human |
| Spencer T Brown, Indira M Rama. Sensorimotor Integration and Amplification of Reflexive Whisking by Well-Timed Spiking in the Cerebellar Corticonuclear Circuit. Neuron. vol 99. issue 3. 2019-08-01. PMID:30017394. |
to test how cerebellar crus i/ii purkinje cells and their targets in the lateral cerebellar nuclei (cbn) integrate sensory and motor-related inputs and contribute to reflexive movements, we recorded extracellularly in awake, head-fixed mice during non-contact whisking. |
2019-08-01 |
2023-08-13 |
mouse |
| Wataru Kakegawa, Akira Katoh, Sakae Narumi, Eriko Miura, Junko Motohashi, Akiyo Takahashi, Kazuhisa Kohda, Yugo Fukazawa, Michisuke Yuzaki, Shinji Matsud. Optogenetic Control of Synaptic AMPA Receptor Endocytosis Reveals Roles of LTD in Motor Learning. Neuron. vol 99. issue 5. 2019-08-01. PMID:30122381. |
we found that fiberoptic illumination to purkinje cells expressing photonsaber in vivo inhibited cerebellar motor learning during adaptation of the horizontal optokinetic response and vestibulo-ocular reflex, as well as synaptic ampa receptor decrease in the flocculus. |
2019-08-01 |
2023-08-13 |
Not clear |
| Muhammad Shahid, Fazal Subhan, Gowhar Ali, Ihsan Ullah, Javaid Alam, Sami Ullah, Khalid Rau. Neuroprotective effect of Bacopa monnieri against morphine-induced histopathological changes in the cerebellum of rats. Pakistan journal of pharmaceutical sciences. vol 30. issue 6. 2019-07-29. PMID:29175775. |
morphine produced vacuolization of basket and stellate cells and reduced the size of purkinje cells in the cerebellum after 14 days. |
2019-07-29 |
2023-08-13 |
rat |
| Yueping Zhang, Gerhard Magnus, Victor Z Ha. Cell type-specific plasticity at parallel fiber synapses onto Purkinje cells in the posterior caudal lobe of the mormyrid fish cerebellum. Journal of neurophysiology. vol 120. issue 2. 2019-07-29. PMID:29668384. |
cell type-specific plasticity at parallel fiber synapses onto purkinje cells in the posterior caudal lobe of the mormyrid fish cerebellum. |
2019-07-29 |
2023-08-13 |
Not clear |
| Yueping Zhang, Gerhard Magnus, Victor Z Ha. Cell type-specific plasticity at parallel fiber synapses onto Purkinje cells in the posterior caudal lobe of the mormyrid fish cerebellum. Journal of neurophysiology. vol 120. issue 2. 2019-07-29. PMID:29668384. |
it has been demonstrated that there are two morphological subtypes of purkinje cells (pcs)-fan-shaped purkinje cells (fpcs) and multipolar purkinje cells (mpcs)-in the posterior caudal lobe of the mormyrid fish cerebellum, but whether these cell types are also functionally distinct is unknown. |
2019-07-29 |
2023-08-13 |
Not clear |
| Sung Min Nam, Jin Seok Seo, Sang-Soep Nahm, Byung-Joon Chan. Effects of Ascorbic Acid on Osteopontin Expression and Axonal Myelination in the Developing Cerebellum of Lead-Exposed Rat Pups. International journal of environmental research and public health. vol 16. issue 6. 2019-07-24. PMID:30893812. |
ascorbic acid treatment mitigated pb exposure-induced reduction in the number of intact purkinje cells and opn immunoreactive purkinje cells in the cerebellum of pups. |
2019-07-24 |
2023-08-13 |
rat |
| Lauren M Watson, Maggie M K Wong, Jane Vowles, Sally A Cowley, Esther B E Becke. A Simplified Method for Generating Purkinje Cells from Human-Induced Pluripotent Stem Cells. Cerebellum (London, England). vol 17. issue 4. 2019-07-23. PMID:29397531. |
the establishment of a reliable model for the study of purkinje cells in vitro is of particular importance, given their central role in cerebellar function and pathology. |
2019-07-23 |
2023-08-13 |
mouse |
| Jan Cendelin, Zdenka Purkartova, Jakub Kubik, Erik Ulbricht, Filip Tichanek, Yaroslav Kolink. Long-Term Development of Embryonic Cerebellar Grafts in Two Strains of Lurcher Mice. Cerebellum (London, England). vol 17. issue 4. 2019-07-23. PMID:29450804. |
in both b6cba and c3h lurcher mice, most of the grafts were strictly delimited with no tendency to invade the host cerebellum, while in wild-type mice, graft-derived purkinje cells colonized the host's cerebellum. |
2019-07-23 |
2023-08-13 |
mouse |
| Rebecca M Long, Janelle M P Pakan, David J Graham, Peter L Hurd, Cristian Gutierrez-Ibañez, Douglas R Wyli. Modulation of complex spike activity differs between zebrin-positive and -negative Purkinje cells in the pigeon cerebellum. Journal of neurophysiology. vol 120. issue 1. 2019-07-16. PMID:29589816. |
modulation of complex spike activity differs between zebrin-positive and -negative purkinje cells in the pigeon cerebellum. |
2019-07-16 |
2023-08-13 |
pigeon |
| Rebecca M Long, Janelle M P Pakan, David J Graham, Peter L Hurd, Cristian Gutierrez-Ibañez, Douglas R Wyli. Modulation of complex spike activity differs between zebrin-positive and -negative Purkinje cells in the pigeon cerebellum. Journal of neurophysiology. vol 120. issue 1. 2019-07-16. PMID:29589816. |
new & noteworthy although the cerebellum appears to be a uniform structure, purkinje cells (pcs) are heterogeneous and can be categorized on the basis of the expression of molecular markers. |
2019-07-16 |
2023-08-13 |
pigeon |
| Efrat Tal, Marina Alfo, Shan Zha, Ari Barzilai, Chris I De Zeeuw, Yael Ziv, Yosef Shilo. Inactive Atm abrogates DSB repair in mouse cerebellum more than does Atm loss, without causing a neurological phenotype. DNA repair. vol 72. 2019-07-16. PMID:30348496. |
the major clinical feature of a-t is cerebellar atrophy, characterized by relentless loss of purkinje and granule cells. |
2019-07-16 |
2023-08-13 |
mouse |
| Naofumi Uesaka, Manabu Abe, Kohtarou Konno, Maya Yamazaki, Kazuto Sakoori, Takaki Watanabe, Tzu-Huei Kao, Takayasu Mikuni, Masahiko Watanabe, Kenji Sakimura, Masanobu Kan. Retrograde Signaling from Progranulin to Sort1 Counteracts Synapse Elimination in the Developing Cerebellum. Neuron. vol 97. issue 4. 2019-07-15. PMID:29398357. |
purkinje cells (pcs) in the neonatal cerebellum are innervated by multiple climbing fibers (cfs) with similar strengths. |
2019-07-15 |
2023-08-13 |
Not clear |
| Ioannis Mavroudi. Cerebellar pathology in Alzheimer's disease. Hellenic journal of nuclear medicine. vol 22 Suppl. 2019-07-12. PMID:30877735. |
although the cerebellum has not been extensively studied in ad, recent studies have revealed evidence of a unique pathological pattern of the cerebellar cortex, including loss of purkinje cells, synaptic alterations in the mossy fibres, granule cell dendrites, parallel fibres and purkinje cell dendrites with substantial loss of dendritic spines, and considerable alterations in ultrathin sections. |
2019-07-12 |
2023-08-13 |
monkey |
| Fitriani Agustina, Zaenal Muttaqien Sofro, Ginus Partadiredj. Subchronic Administration of High-Dose Sodium Fluoride Causes Deficits in Cerebellar Purkinje Cells But Not Motor Coordination of Rats. Biological trace element research. vol 188. issue 2. 2019-07-08. PMID:29951727. |
the damage of the purkinje cells of the cerebellum can lead to motor coordination disorders. |
2019-07-08 |
2023-08-13 |
rat |
| Fitriani Agustina, Zaenal Muttaqien Sofro, Ginus Partadiredj. Subchronic Administration of High-Dose Sodium Fluoride Causes Deficits in Cerebellar Purkinje Cells But Not Motor Coordination of Rats. Biological trace element research. vol 188. issue 2. 2019-07-08. PMID:29951727. |
the present study aimed at investigating the effects of sodium fluoride on the motor coordination and the number of purkinje cells of the cerebellum of rats. |
2019-07-08 |
2023-08-13 |
rat |
| Fitriani Agustina, Zaenal Muttaqien Sofro, Ginus Partadiredj. Subchronic Administration of High-Dose Sodium Fluoride Causes Deficits in Cerebellar Purkinje Cells But Not Motor Coordination of Rats. Biological trace element research. vol 188. issue 2. 2019-07-08. PMID:29951727. |
the administration of sodium fluoride at doses of 10 and 20 mg/kg bw caused a decrease in the number of purkinje cells of the cerebellum in rats. |
2019-07-08 |
2023-08-13 |
rat |
| Kevin C Kemp, Rimi Dey, Johan Verhagen, Neil J Scolding, Maria M Usowicz, Alastair Wilkin. Aberrant cerebellar Purkinje cell function repaired in vivo by fusion with infiltrating bone marrow-derived cells. Acta neuropathologica. vol 135. issue 6. 2019-07-01. PMID:29541917. |
extracellular recording of spontaneous firing ex vivo revealed a shift in the predominant mode of firing of non-fused purkinje cells in the context of cerebellar inflammation. |
2019-07-01 |
2023-08-13 |
mouse |
| Kevin C Kemp, Rimi Dey, Johan Verhagen, Neil J Scolding, Maria M Usowicz, Alastair Wilkin. Aberrant cerebellar Purkinje cell function repaired in vivo by fusion with infiltrating bone marrow-derived cells. Acta neuropathologica. vol 135. issue 6. 2019-07-01. PMID:29541917. |
by contrast, the firing patterns of fused purkinje cells were the same as in healthy control cerebellum, indicating that fusion of bone marrow-derived cells with purkinje cells mitigated the effects of cell injury on electrical activity. |
2019-07-01 |
2023-08-13 |
mouse |