| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Julie Marie Lefort, Jean Vincent, Lucille Tallot, Frédéric Jarlier, Chris Innocentius De Zeeuw, Laure Rondi-Reig, Christelle Rochefor. Impaired cerebellar Purkinje cell potentiation generates unstable spatial map orientation and inaccurate navigation. Nature communications. vol 10. issue 1. 2019-07-01. PMID:31113954. |
cerebellar activity supported by pkc-dependent long-term depression in purkinje cells (pcs) is involved in the stabilization of self-motion based hippocampal representation, but the existence of cerebellar processes underlying integration of allocentric cues remains unclear. |
2019-07-01 |
2023-08-13 |
mouse |
| Vien Nguyen, Khalida Sabeur, Emin Maltepe, Kurosh Ameri, Omer Bayraktar, David H Rowitc. Sonic Hedgehog Agonist Protects Against Complex Neonatal Cerebellar Injury. Cerebellum (London, England). vol 17. issue 2. 2019-06-26. PMID:29134361. |
however, in mice administered prednisolone, hif overactivation in cgnps resulted in significant cerebellar hypoplasia, whereas hif overactivation in purkinje cells caused cell death. |
2019-06-26 |
2023-08-13 |
mouse |
| Satoko Suzuki, Noriko Ayukawa, Chisa Okada, Masami Tanaka, Susumu Takekoshi, Yoko Iijima, Takatoshi Iijim. Spatio-temporal and dynamic regulation of neurofascin alternative splicing in mouse cerebellar neurons. Scientific reports. vol 7. issue 1. 2019-06-21. PMID:28900163. |
we then identified distinct nfasc splicing patterns at the cell-type level in the cerebellum, with nfasc186 being expressed in purkinje cells and absent from granule cells (gcs). |
2019-06-21 |
2023-08-13 |
mouse |
| Richard Hawke. The Ferdinando Rossi Memorial Lecture: Zones and Stripes-Pattern Formation in the Cerebellum. Cerebellum (London, England). vol 17. issue 1. 2019-06-14. PMID:28965328. |
purkinje cells in the mouse cerebellum come in many different subtypes, identifiable by expression markers, sensitivity to mutation, etc. |
2019-06-14 |
2023-08-13 |
mouse |
| Saša Jereb, Hun-Way Hwang, Eric Van Otterloo, Eve-Ellen Govek, John J Fak, Yuan Yuan, Mary E Hatten, Robert B Darnel. Differential 3' Processing of Specific Transcripts Expands Regulatory and Protein Diversity Across Neuronal Cell Types. eLife. vol 7. 2019-06-03. PMID:29578408. |
using a new technique, ctag-paperclip, we discovered significant differences in apa between the principal types of mouse cerebellar neurons, the purkinje and granule cells, as well as between proliferating and differentiated granule cells. |
2019-06-03 |
2023-08-13 |
mouse |
| Ryosuke Tsumagari, Yasuhito Shira. [Importance of diacylglycerol signaling in cerebellar motor coordination]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 152. issue 2. 2019-05-30. PMID:30101866. |
therefore, we developed dgkγ knockout (ko) mice and investigated their ltd, morphology of purkinje cells, and cerebellar motor coordination. |
2019-05-30 |
2023-08-13 |
mouse |
| Ryosuke Tsumagari, Yasuhito Shira. [Importance of diacylglycerol signaling in cerebellar motor coordination]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 152. issue 2. 2019-05-30. PMID:30101866. |
we found that cerebellar motor coordination and ltd were impaired in the dgkγ ko mice and the morphology of purkinje cells from dgkγ ko mice was significantly retracted. |
2019-05-30 |
2023-08-13 |
mouse |
| Ryosuke Tsumagari, Yasuhito Shira. [Importance of diacylglycerol signaling in cerebellar motor coordination]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 152. issue 2. 2019-05-30. PMID:30101866. |
these results indicated that dgkγ was involved in cerebellar ltd and morphology of purkinje cells, and dg signaling is important for cerebellar motor coordination. |
2019-05-30 |
2023-08-13 |
mouse |
| David Burke, G Michael Halmagy. Normal tendon reflexes despite absent sensory nerve action potentials in CANVAS: a neurophysiological study. Journal of the neurological sciences. vol 387. 2019-05-28. PMID:29571876. |
canvas is a recently defined progressive ataxic syndrome with impairment of vestibular, somatosensory and cerebellar function due to atrophic degeneration of dorsal root ganglia and dorsal columns, of cranial nerve somatosensory ganglia, of vestibular ganglia and vestibular nerves and of cerebellar purkinje cells. |
2019-05-28 |
2023-08-13 |
Not clear |
| Rashmi Sarnaik, Indira M Rama. Control of voluntary and optogenetically perturbed locomotion by spike rate and timing of neurons of the mouse cerebellar nuclei. eLife. vol 7. 2019-05-28. PMID:29659351. |
neurons of the cerebellar nuclei (cbn), which generate cerebellar output, are inhibited by purkinje cells. |
2019-05-28 |
2023-08-13 |
mouse |
| Simone Vodret, Giulia Bortolussi, Alessandra Iaconcig, Elena Martinelli, Claudio Tiribelli, Andrés F Mur. Attenuation of neuro-inflammation improves survival and neurodegeneration in a mouse model of severe neonatal hyperbilirubinemia. Brain, behavior, and immunity. vol 70. 2019-05-21. PMID:29458193. |
from the molecular point of view, rescued mice showed a dose-dependent reduction in apoptosis of cerebellar neurons and improvement of dendritic arborization of purkinje cells. |
2019-05-21 |
2023-08-13 |
mouse |
| Shin-Wu Liu, Jui-Chih Chang, Sheng-Fei Chuang, Ko-Hung Liu, Wen-Ling Cheng, Hui-Ju Chang, Huei-Shin Chang, Ta-Tsung Lin, Ching-Liang Hsieh, Wei-Yong Lin, Mingli Hsieh, Shou-Jen Kuo, Chin-San Li. Far-infrared Radiation Improves Motor Dysfunction and Neuropathology in Spinocerebellar Ataxia Type 3 Mice. Cerebellum (London, England). vol 18. issue 1. 2019-05-20. PMID:29725949. |
the results showed that the 84q sca3 mice displayed impaired motor coordination, balance abilities, and gait performance, along with the associated loss of purkinje cells in the cerebellum, compared with the normal 15q controls; nevertheless, fir treatment was sufficient to prevent those defects. |
2019-05-20 |
2023-08-13 |
mouse |
| Shin-Wu Liu, Jui-Chih Chang, Sheng-Fei Chuang, Ko-Hung Liu, Wen-Ling Cheng, Hui-Ju Chang, Huei-Shin Chang, Ta-Tsung Lin, Ching-Liang Hsieh, Wei-Yong Lin, Mingli Hsieh, Shou-Jen Kuo, Chin-San Li. Far-infrared Radiation Improves Motor Dysfunction and Neuropathology in Spinocerebellar Ataxia Type 3 Mice. Cerebellum (London, England). vol 18. issue 1. 2019-05-20. PMID:29725949. |
moreover, fir treatment supported the survival of purkinje cells in the cerebellum and promoted the autophagy, as reflected by the induction of autophagic markers, lc3ii and beclin-1, concomitant with the reduction of p62 and ataxin-3 accumulation in cerebellar purkinje cells, which might partially contribute to the rescue mechanism. |
2019-05-20 |
2023-08-13 |
mouse |
| Polina A Egorova, Alexandra V Gavrilova, Ilya B Bezprozvann. In Vivo Analysis of the Climbing Fiber-Purkinje Cell Circuit in SCA2-58Q Transgenic Mouse Model. Cerebellum (London, England). vol 17. issue 5. 2019-05-20. PMID:29876801. |
cerebellar purkinje cells (pcs) and cerebellar pathways are primarily affected in many autosomal dominant cerebellar ataxias. |
2019-05-20 |
2023-08-13 |
mouse |
| Richard Apps, Richard Hawkes, Sho Aoki, Fredrik Bengtsson, Amanda M Brown, Gang Chen, Timothy J Ebner, Philippe Isope, Henrik Jörntell, Elizabeth P Lackey, Charlotte Lawrenson, Bridget Lumb, Martijn Schonewille, Roy V Sillitoe, Ludovic Spaeth, Izumi Sugihara, Antoine Valera, Jan Voogd, Douglas R Wylie, Tom J H Ruigro. Cerebellar Modules and Their Role as Operational Cerebellar Processing Units: A Consensus paper [corrected]. Cerebellum (London, England). vol 17. issue 5. 2019-05-20. PMID:29876802. |
furthermore, it has become clear that chemical diversity of purkinje cells also results in diversity of information processing between cerebellar modules. |
2019-05-20 |
2023-08-13 |
human |
| Hannah Hayhurst, Maria-Eleni Anagnostou, Helen J Bogle, John P Grady, Robert W Taylor, Laurence A Bindoff, Robert McFarland, Doug M Turnbull, Nichola Z La. Dissecting the neuronal vulnerability underpinning Alpers' syndrome: a clinical and neuropathological study. Brain pathology (Zurich, Switzerland). vol 29. issue 1. 2019-05-20. PMID:30021052. |
quantitative immunofluorescence showed severe respiratory chain deficiencies involving mitochondrial respiratory chain subunits of complex i and, to a lesser extent, complex iv in inhibitory interneurons and pyramidal neurons in the occipital cortex and in purkinje cells of the cerebellum. |
2019-05-20 |
2023-08-13 |
Not clear |
| David J Herzfeld, Yoshiko Kojima, Robijanto Soetedjo, Reza Shadmeh. Encoding of error and learning to correct that error by the Purkinje cells of the cerebellum. Nature neuroscience. vol 21. issue 5. 2019-05-15. PMID:29662213. |
encoding of error and learning to correct that error by the purkinje cells of the cerebellum. |
2019-05-15 |
2023-08-13 |
Not clear |
| Masanobu Kano, Takaki Watanabe, Naofumi Uesaka, Masahiko Watanab. Multiple Phases of Climbing Fiber Synapse Elimination in the Developing Cerebellum. Cerebellum (London, England). vol 17. issue 6. 2019-05-13. PMID:30009357. |
in the cerebellum of neonatal rodents, excitatory synapses are formed on the somata of purkinje cells (pcs) by climbing fibers (cfs) that originate from neurons in the contralateral inferior olive. |
2019-05-13 |
2023-08-13 |
Not clear |
| Adolfo Soto-Domínguez, Humberto Rodríguez-Rocha, Aracely García-García, Odila Saucedo-Cárdenas, Luis E Rodríguez-Tovar, Uziel Castillo-Velázque. Mature congenital intraneural teratoma in cerebellum of pig. Histology and histopathology. vol 34. issue 2. 2019-05-10. PMID:30183058. |
sections from the teratoma showed normal histology of the cerebellum, including rounded purkinje neurons with abundant cytoplasm, euchromatic nuclei, and prominent nucleoli; glial cells with a scarce amount of cytoplasm and small and highly basophile-nuclei (compact chromatin) and axonal tracts (white matter). |
2019-05-10 |
2023-08-13 |
Not clear |
| Ye Yu, Jing Dong, Yuan Wang, Yi Wang, Hui Min, Zhong Yan Shan, Wei Ping Teng, Jie Che. Effects of Maternal Marginal Iodine Deficiency on Interactions between Cerebellar Bergmann Glia Cells and Purkinje Cells in Rat Offspring. Biomedical and environmental sciences : BES. vol 30. issue 12. 2019-05-08. PMID:29335065. |
effects of maternal marginal iodine deficiency on interactions between cerebellar bergmann glia cells and purkinje cells in rat offspring. |
2019-05-08 |
2023-08-13 |
rat |