| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Regina T Martuscello, Elan D Louis, Phyllis L Faus. A Stainless Protocol for High Quality RNA Isolation from Laser Capture Microdissected Purkinje Cells in the Human Post-Mortem Cerebellum. Journal of visualized experiments : JoVE. issue 143. 2020-01-24. PMID:30735198. |
here, we present a full protocol for sectioning and fixing fresh frozen post-mortem human cerebellar tissue and purification of rna from purkinje cells isolated by uv-lcm, while preserving rna quality for subsequent rna-sequencing. |
2020-01-24 |
2023-08-13 |
human |
| Murad Alturkustani, Lee-Cyn An. Claustral neurons are vulnerable to ischemic insults in cardiac arrest encephalopathy. International journal of clinical and experimental pathology. vol 11. issue 5. 2020-01-19. PMID:31938390. |
selective vulnerability is the common form of ischemic injury in these cases and commonly affects the ca1 of hippocampus, cerebral cortex in watershed zone and purkinje cells of the cerebellum. |
2020-01-19 |
2023-08-13 |
Not clear |
| Ryuji Dohaku, Masahiro Yamaguchi, Naoyuki Yamamoto, Takashi Shimizu, Fumitaka Osakada, Masahiko Hib. Tracing of Afferent Connections in the Zebrafish Cerebellum Using Recombinant Rabies Virus. Frontiers in neural circuits. vol 13. 2020-01-13. PMID:31068795. |
for the specific infection of cerebellar neurons, we expressed the rv glycoprotein (g) gene and the envelope protein tva, which is the receptor for enva, in purkinje cells (pcs) or granule cells (gcs), using the promoter for |
2020-01-13 |
2023-08-13 |
zebrafish |
| Obelia Haida, Tareq Al Sagheer, Anais Balbous, Maureen Francheteau, Emmanuel Matas, Federico Soria, Pierre Olivier Fernagut, Mohamed Jabe. Sex-dependent behavioral deficits and neuropathology in a maternal immune activation model of autism. Translational psychiatry. vol 9. issue 1. 2020-01-09. PMID:30923308. |
reduced numbers of purkinje cells in the cerebellum was found more widespread and within distinct lobules in males than in females. |
2020-01-09 |
2023-08-13 |
mouse |
| Cecilia Mancini, Eriola Hoxha, Luisa Iommarini, Alessandro Brussino, Uwe Richter, Francesca Montarolo, Claudia Cagnoli, Roberta Parolisi, Diana Iulia Gondor Morosini, Valentina Nicolò, Francesca Maltecca, Luisa Muratori, Giulia Ronchi, Stefano Geuna, Francesca Arnaboldi, Elena Donetti, Elisa Giorgio, Simona Cavalieri, Eleonora Di Gregorio, Elisa Pozzi, Marta Ferrero, Evelise Riberi, Giorgio Casari, Fiorella Altruda, Emilia Turco, Giuseppe Gasparre, Brendan J Battersby, Anna Maria Porcelli, Enza Ferrero, Alfredo Brusco, Filippo Tempi. Mice harbouring a SCA28 patient mutation in AFG3L2 develop late-onset ataxia associated with enhanced mitochondrial proteotoxicity. Neurobiology of disease. vol 124. 2019-12-23. PMID:30389403. |
although cerebellar pathology was negative, electrophysiological analysis showed a trend towards increased spontaneous firing in purkinje cells from heterozygous mutants with respect to wild-type controls. |
2019-12-23 |
2023-08-13 |
mouse |
| Takahiro Sek. [Exploration of preventive drugs for spinocerebellar ataxia using cultured cerebellar Purkinje cells]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 154. issue 6. 2019-12-09. PMID:31787682. |
cerebellar purkinje cells (pcs) are sole output neurons from cerebellar cortexes, crucial for cerebellar functions and characterized highly branched dendrites. |
2019-12-09 |
2023-08-13 |
mouse |
| Hirokazu Tanaka, Takahiro Ishikawa, Shinji Kake. Neural Evidence of the Cerebellum as a State Predictor. Cerebellum (London, England). vol 18. issue 3. 2019-12-06. PMID:30627965. |
to test the forward-model hypothesis, we analyzed activities of 94 mossy fibers (inputs to the cerebellar cortex), 83 purkinje cells (output from the cerebellar cortex to dentate nucleus), and 73 dentate nucleus cells (cerebellar output) in the cerebro-cerebellum, all recorded from a monkey performing step-tracking movements of the right wrist. |
2019-12-06 |
2023-08-13 |
monkey |
| Christopher J Alexander, John A Hamme. An Improved Method for Differentiating Mouse Embryonic Stem Cells into Cerebellar Purkinje Neurons. Cerebellum (London, England). vol 18. issue 3. 2019-12-06. PMID:30729383. |
while mixed primary cerebellar cultures prepared from embryonic tissue have proven valuable for dissecting structure-function relationships in cerebellar purkinje neurons (pns), this technique is technically challenging and often yields few cells. |
2019-12-06 |
2023-08-13 |
mouse |
| Emma M Perkins, Yvonne L Clarkson, Daumante Suminaite, Alastair R Lyndon, Kohichi Tanaka, Jeffrey D Rothstein, Paul A Skehel, David J A Wyllie, Mandy Jackso. Loss of cerebellar glutamate transporters EAAT4 and GLAST differentially affects the spontaneous firing pattern and survival of Purkinje cells. Human molecular genetics. vol 27. issue 15. 2019-12-03. PMID:29741614. |
loss of cerebellar glutamate transporters eaat4 and glast differentially affects the spontaneous firing pattern and survival of purkinje cells. |
2019-12-03 |
2023-08-13 |
mouse |
| Tiziano Balzano, Jerónimo Forteza, Pilar Molina, Juan Giner, Ana Monzó, Jennifer Sancho-Jiménez, Amparo Urios, Carmina Montoliu, Vicente Felip. The Cerebellum of Patients with Steatohepatitis Shows Lymphocyte Infiltration, Microglial Activation and Loss of Purkinje and Granular Neurons. Scientific reports. vol 8. issue 1. 2019-11-25. PMID:29445232. |
the cerebellum of patients with steatohepatitis shows lymphocyte infiltration, microglial activation and loss of purkinje and granular neurons. |
2019-11-25 |
2023-08-13 |
Not clear |
| Tiziano Balzano, Jerónimo Forteza, Pilar Molina, Juan Giner, Ana Monzó, Jennifer Sancho-Jiménez, Amparo Urios, Carmina Montoliu, Vicente Felip. The Cerebellum of Patients with Steatohepatitis Shows Lymphocyte Infiltration, Microglial Activation and Loss of Purkinje and Granular Neurons. Scientific reports. vol 8. issue 1. 2019-11-25. PMID:29445232. |
our aim was to analyze in cerebellum of patients with different grades of liver disease, from mild steatohepatitis to cirrhosis and hepatic encephalopathy: (a) neuronal density in purkinje and granular layers; (b) microglial activation; (c) astrocyte activation; (d) peripheral lymphocytes infiltration; (e) subtypes of lymphocytes infiltrated. |
2019-11-25 |
2023-08-13 |
Not clear |
| Kiyotoshi Satoh, Tsuyoshi Morishita, Keiko Haraguchi, Naoto Kakinuma, Tetsu Akiyama, T. Send. Expression and localization of the LGN protein in the mouse brain with reference to its relationship with Galphai2. Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan. vol 32. issue 4. 2019-11-20. PMID:11810449. |
immunofluorescence microscopy showed that lgn is localized in nuclei of the neurons in the olfactory bulb, cerebral cortex, and hippocampus, but in both nuclei and cytoplasm of purkinje cells in the cerebellum. |
2019-11-20 |
2023-08-12 |
mouse |
| M. Krupa, F. Crepe. Transient Sensitivity of Rat Cerebellar Purkinje Cells to N-methyl-D-aspartate during Development. A Voltage Clamp Study in in vitro Slices. The European journal of neuroscience. vol 2. issue 4. 2019-11-20. PMID:12106038. |
in vitro sagittal slices of immature rat cerebellum were used to study the development of the sensitivity of purkinje cells (pc) to l-glutamate (glu) and n-methyl-d-aspartate (nmda). |
2019-11-20 |
2023-08-12 |
rat |
| Salvador Martinez, Rosa-Magda Alvarado-Mallar. Rostral Cerebellum Originates from the Caudal Portion of the So-Called 'Mesencephalic' Vesicle: A Study Using Chick/Quail Chimeras. The European journal of neuroscience. vol 1. issue 6. 2019-11-20. PMID:12106114. |
among the quail cortical neurons, the purkinje cells, although intermingled with host purkinje cells, are organized, at e18, in a characteristic longitudinal band which is strongly reminiscent of the longitudinal functional and morphological organization of the cerebellum. |
2019-11-20 |
2023-08-12 |
chicken |
| K. Sasaki, J. M. Bower, R. Lliná. Multiple Purkinje Cell Recording in Rodent Cerebellar Cortex. The European journal of neuroscience. vol 1. issue 6. 2019-11-20. PMID:12106116. |
the spatial and temporal organization of climbing fibre activation of purkinje cells, the so-called complex spikes, were studied in the rat cerebellar crus ii folium utilizing a multiple microeletrode recording technique. |
2019-11-20 |
2023-08-12 |
rat |
| R. Llinás, K. Sasak. The Functional Organization of the Olivo-Cerebellar System as Examined by Multiple Purkinje Cell Recordings. The European journal of neuroscience. vol 1. issue 6. 2019-11-20. PMID:12106117. |
multiple recordings from purkinje cells in the rat cerebellum allowed the mechanism responsible for the activation of rows of synchronous complex spikes to be investigated. |
2019-11-20 |
2023-08-12 |
rat |
| José Angel Armengol, Constantino Sotelo, Pierre Angaut, Rosa-Magda Alvarado-Mallar. Organization of Host Afferents to Cerebellar Grafts Implanted into Kainate Lesioned Cerebellum in Adult Rats. The European journal of neuroscience. vol 1. issue 1. 2019-11-20. PMID:12106176. |
one month after a cerebellar injection of kainic acid, the lesion produced can be divided into two concentric regions: (i) a central necrotic zone, totally depleted of neurons (zone 1), and (ii) a peripheral zone which lacks all purkinje cells but preserves its cortical lamination (zone 2). |
2019-11-20 |
2023-08-12 |
rat |
| T. Knöpfel, I. Vranesic, C. Staub, B. H. Gähwile. Climbing Fibre Responses in Olivo-cerebellar Slice Cultures. II. Dynamics of Cytosolic Calcium in Purkinje Cells. The European journal of neuroscience. vol 3. issue 4. 2019-11-20. PMID:12106192. |
the generation of climbing fibre responses in cerebellar purkinje cells has been analysed in co-cultured slices of rat cerebellum and inferior olive. |
2019-11-20 |
2023-08-12 |
rat |
| C. Staub, I. Vranesic, T. Knöpfe. Responses to Metabotropic Glutamate Receptor Activation in Cerebellar Purkinje Cells: Induction of an Inward Current. The European journal of neuroscience. vol 4. issue 9. 2019-11-20. PMID:12106306. |
the responses to activation of metabotropic glutamate receptors (mglurs) of purkinje cells in rat cerebellar slice cultures were investigated using intracellular recordings in single-electrode voltage-clamp mode combined with microfluorometric measurements of cytosolic free calcium using fura-2. |
2019-11-20 |
2023-08-12 |
rat |
| I. Torres-Aleman, S. Pons, F. F. Santos-Benit. Survival of Purkinje Cells in Cerebellar Cultures is Increased by Insulin-like Growth Factor I. The European journal of neuroscience. vol 4. issue 9. 2019-11-20. PMID:12106309. |
survival of purkinje cells in cerebellar cultures is increased by insulin-like growth factor i. insulin-like growth factor i (igf-i) is a trophic factor for both neurons and glia. |
2019-11-20 |
2023-08-12 |
rat |