| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sho Aoki, Patrice Coulon, Tom J H Ruigro. Multizonal Cerebellar Influence Over Sensorimotor Areas of the Rat Cerebral Cortex. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 2. 2020-04-03. PMID:29300895. |
rabv+ purkinje cells throughout cerebellar zones were identified by reference to the cerebellar zebrin pattern. |
2020-04-03 |
2023-08-13 |
rat |
| Rowena Cayabyab, Rangasamy Ramanatha. High unbound bilirubin for age: a neurotoxin with major effects on the developing brain. Pediatric research. vol 85. issue 2. 2020-04-02. PMID:30518884. |
the neuropathological finding of bilirubin-induced neurotoxicity also includes cerebellar injury with a decreased number of purkinje cells, and disruption of multisensory feedback loop between cerebellum and cortical neurons which may explain the clinical characteristics of autism spectrum disorders. |
2020-04-02 |
2023-08-13 |
Not clear |
| Kyoko Ibaraki, Nanako Hamada, Ikuko Iwamoto, Hidenori Ito, Noriko Kawamura, Rika Morishita, Hidenori Tabata, Koh-Ichi Nagat. Expression Analyses of POGZ, A Responsible Gene for Neurodevelopmental Disorders, during Mouse Brain Development. Developmental neuroscience. vol 41. issue 1-2. 2020-03-30. PMID:31430754. |
the nuclear expression was also detected in purkinje cells in cerebellum at postnatal day (p)7 and p15 but disappeared at p30. |
2020-03-30 |
2023-08-13 |
mouse |
| Sung Min Nam, Jin Seok Seo, Sang-Soep Nahm, Byung-Joon Chan. Effects of ascorbic acid treatment on developmental alterations in calcium-binding proteins and gamma-aminobutyric acid transporter 1 in the cerebellum of lead-exposed rats during pregnancy and lactation. The Journal of toxicological sciences. vol 44. issue 11. 2020-03-30. PMID:31708536. |
nissl staining demonstrated that the number of purkinje cells was significantly reduced following pb exposure, while ascorbic acid ameliorated this effect in the cerebellum of the offspring. |
2020-03-30 |
2023-08-13 |
rat |
| Gabriele Schele. Logarithmic distributions prove that intrinsic learning is Hebbian. F1000Research. vol 6. 2020-03-09. PMID:29071065. |
the difference between strongly recurrent and feed-forward connectivity (cortex vs. striatum and cerebellum), neurotransmitter (gaba (striatum) or glutamate (cortex)) or the level of activation (low in cortex, high in purkinje cells and midbrain nuclei) turns out to be irrelevant for this feature. |
2020-03-09 |
2023-08-13 |
Not clear |
| Kazuyoshi Tsutsu. Kobayashi award: Discovery of cerebellar and pineal neurosteroids and their biological actions on the growth and survival of Purkinje cells during development (review). General and comparative endocrinology. vol 284. 2020-02-25. PMID:30339808. |
kobayashi award: discovery of cerebellar and pineal neurosteroids and their biological actions on the growth and survival of purkinje cells during development (review). |
2020-02-25 |
2023-08-13 |
Not clear |
| Kazuyoshi Tsutsu. Kobayashi award: Discovery of cerebellar and pineal neurosteroids and their biological actions on the growth and survival of Purkinje cells during development (review). General and comparative endocrinology. vol 284. 2020-02-25. PMID:30339808. |
futhermore, allopregnanolone (3α,5α-tetrahydroprogesterone), a progesterone metabolite, is also synthesized in the cerebellum and acts on the survival of purkinje cells. |
2020-02-25 |
2023-08-13 |
Not clear |
| Kazuyoshi Tsutsu. Kobayashi award: Discovery of cerebellar and pineal neurosteroids and their biological actions on the growth and survival of Purkinje cells during development (review). General and comparative endocrinology. vol 284. 2020-02-25. PMID:30339808. |
i as a recipient of kobayashi award from the japan society for comparative endocrinology in 2016 summarize the discovery of cerebellar and pineal neurosteroids and their biological actions on the growth and survival of purkinje cells during development. |
2020-02-25 |
2023-08-13 |
Not clear |
| Elan D Louis, Phyllis L Faus. Essential tremor pathology: neurodegeneration and reorganization of neuronal connections. Nature reviews. Neurology. vol 16. issue 2. 2020-02-19. PMID:31959938. |
these studies identified abnormalities in the cerebellum, which primarily affected purkinje cells (pcs), basket cells and climbing fibres, in individuals with et. |
2020-02-19 |
2023-08-13 |
Not clear |
| Hannah L Payne, Ranran L French, Christine C Guo, Td Barbara Nguyen-Vu, Tiina Manninen, Jennifer L Raymon. Cerebellar Purkinje cells control eye movements with a rapid rate code that is invariant to spike irregularity. eLife. vol 8. 2020-02-18. PMID:31050648. |
in the cerebellum, it has been hypothesized that the irregularity of interspike intervals in purkinje cells affects their ability to transmit information to downstream neurons. |
2020-02-18 |
2023-08-13 |
mouse |
| Hassan Marzban, Maryam Rahimi-Balaei, Richard Hawke. Early trigeminal ganglion afferents enter the cerebellum before the Purkinje cells are born and target the nuclear transitory zone. Brain structure & function. vol 224. issue 7. 2020-02-18. PMID:31256239. |
early trigeminal ganglion afferents enter the cerebellum before the purkinje cells are born and target the nuclear transitory zone. |
2020-02-18 |
2023-08-13 |
mouse |
| Hassan Marzban, Maryam Rahimi-Balaei, Richard Hawke. Early trigeminal ganglion afferents enter the cerebellum before the Purkinje cells are born and target the nuclear transitory zone. Brain structure & function. vol 224. issue 7. 2020-02-18. PMID:31256239. |
the finding that the earliest axons to the cerebellum derive from the trigeminal ganglion and enter the cerebellar primordium before the purkinje cells are born, where they seem to target the cerebellar nuclei, reveals a novel stage in the development of the cerebellar afferents. |
2020-02-18 |
2023-08-13 |
mouse |
| Shintaro Saegusa, Masahiro Fukaya, Wataru Kakegawa, Manabu Tanaka, Osamu Katsumata, Takeyuki Sugawara, Yoshinobu Hara, Makoto Itakura, Tadashi Okubo, Toshiya Sato, Michisuke Yuzaki, Hiroyuki Sakagam. Mice lacking EFA6C/Psd2, a guanine nucleotide exchange factor for Arf6, exhibit lower Purkinje cell synaptic density but normal cerebellar motor functions. PloS one. vol 14. issue 5. 2020-02-11. PMID:31095630. |
electron microscopic observation of the cerebellar molecular layer revealed that the density of asymmetric synapses of purkinje cells was significantly lower in efa6c ko mice compared with wild-type control mice. |
2020-02-11 |
2023-08-13 |
mouse |
| Sara Murru, Simon Hess, Esther Barth, Eva R Almajan, Désirée Schatton, Steffen Hermans, Susanne Brodesser, Thomas Langer, Peter Kloppenburg, Elena I Rugarl. Astrocyte-specific deletion of the mitochondrial m-AAA protease reveals glial contribution to neurodegeneration. Glia. vol 67. issue 8. 2020-02-10. PMID:30989755. |
here, we investigate the role of afg3l2 and its redundant homologue afg3l1 in the bergmann glia (bg), radial astrocytes of the cerebellum that have functional connections with purkinje cells (pc) and regulate glutamate homeostasis. |
2020-02-10 |
2023-08-13 |
mouse |
| Sung Min Nam, Jin Seok Seo, Tae-Hun Go, Sang-Soep Nahm, Byung-Joon Chan. Ascorbic Acid Supplementation Prevents the Detrimental Effects of Prenatal and Postnatal Lead Exposure on the Purkinje Cell and Related Proteins in the Cerebellum of Developing Rats. Biological trace element research. vol 190. issue 2. 2020-02-04. PMID:30488169. |
in the cerebellum, pb exposure significantly reduced purkinje cells and ascorbic acid prevented their reduction. |
2020-02-04 |
2023-08-13 |
rat |
| Sung Min Nam, Jin Seok Seo, Tae-Hun Go, Sang-Soep Nahm, Byung-Joon Chan. Ascorbic Acid Supplementation Prevents the Detrimental Effects of Prenatal and Postnatal Lead Exposure on the Purkinje Cell and Related Proteins in the Cerebellum of Developing Rats. Biological trace element research. vol 190. issue 2. 2020-02-04. PMID:30488169. |
along with the change of the purkinje cells, long-term pb exposure significantly reduced the expression of the synaptic marker (synaptophysin), γ-aminobutyric acid (gaba)-synthesizing enzyme (glutamic acid decarboxylase 67), and axonal myelin basic protein while ascorbic acid co-treatment attenuated pb-mediated reduction of these proteins in the cerebellum of pups. |
2020-02-04 |
2023-08-13 |
rat |
| Sung Min Nam, Jin Seok Seo, Tae-Hun Go, Sang-Soep Nahm, Byung-Joon Chan. Ascorbic Acid Supplementation Prevents the Detrimental Effects of Prenatal and Postnatal Lead Exposure on the Purkinje Cell and Related Proteins in the Cerebellum of Developing Rats. Biological trace element research. vol 190. issue 2. 2020-02-04. PMID:30488169. |
although further studies are required about the neurotoxicity of the pb exposure, the results presented here suggest that developmental pb exposure disrupted normal development of purkinje cells by increasing glutamatergic and oxidative stress in the cerebellum. |
2020-02-04 |
2023-08-13 |
rat |
| Sung Min Nam, Jin Seok Seo, Tae-Hun Go, Sang-Soep Nahm, Byung-Joon Chan. Ascorbic Acid Supplementation Prevents the Detrimental Effects of Prenatal and Postnatal Lead Exposure on the Purkinje Cell and Related Proteins in the Cerebellum of Developing Rats. Biological trace element research. vol 190. issue 2. 2020-02-04. PMID:30488169. |
additionally, ascorbic acid co-treatment is beneficial in attenuating prenatal and postnatal pb exposure-induced maldevelopment of purkinje cells in the developing cerebellum. |
2020-02-04 |
2023-08-13 |
rat |
| Yunliang Zang, Stéphane Dieudonné, Erik De Schutte. Voltage- and Branch-Specific Climbing Fiber Responses in Purkinje Cells. Cell reports. vol 24. issue 6. 2020-01-27. PMID:30089264. |
climbing fibers (cfs) provide instructive signals driving cerebellar learning, but mechanisms causing the variable cf responses in purkinje cells (pcs) are not fully understood. |
2020-01-27 |
2023-08-13 |
Not clear |
| Regina T Martuscello, Elan D Louis, Phyllis L Faus. A Stainless Protocol for High Quality RNA Isolation from Laser Capture Microdissected Purkinje Cells in the Human Post-Mortem Cerebellum. Journal of visualized experiments : JoVE. issue 143. 2020-01-24. PMID:30735198. |
a stainless protocol for high quality rna isolation from laser capture microdissected purkinje cells in the human post-mortem cerebellum. |
2020-01-24 |
2023-08-13 |
human |