| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jan Voog. The Theories of Gerbrandus Jelgersma (1859-1942) on the Function of the Cerebellum. Cerebellum (London, England). 2021-08-12. PMID:34383219. |
based on his observations on the double innervation of the purkinje cells, he formulated a hypothesis on the function of the cerebellum. |
2021-08-12 |
2023-08-13 |
Not clear |
| Jan Voog. The Theories of Gerbrandus Jelgersma (1859-1942) on the Function of the Cerebellum. Cerebellum (London, England). 2021-08-12. PMID:34383219. |
jelgersma's theories are discussed against the background of more recent theories of cerebellar function that, similarly, are based on the double innervation of the purkinje cells. |
2021-08-12 |
2023-08-13 |
Not clear |
| Felipe Cunha, Kelsey Racicot, Janae Nahirney, Courtney Heuston, Douglas R Wylie, Andrew N Iwaniu. Allometric Scaling Rules of the Cerebellum in Galliform Birds. Brain, behavior and evolution. vol 95. issue 2. 2021-08-10. PMID:32739912. |
recent comparative studies have examined the allometric rules between cerebellar mass and number of neurons, but data are lacking on the numbers and sizes of purkinje and granule cells or scaling of cerebellar foliation. |
2021-08-10 |
2023-08-13 |
Not clear |
| Felipe Cunha, Kelsey Racicot, Janae Nahirney, Courtney Heuston, Douglas R Wylie, Andrew N Iwaniu. Allometric Scaling Rules of the Cerebellum in Galliform Birds. Brain, behavior and evolution. vol 95. issue 2. 2021-08-10. PMID:32739912. |
here, we investigate the allometric rules that govern variation in the volumes of the layers of the cerebellum, the numbers and sizes of purkinje cells and granule cells and the degree of the cerebellar foliation across 7 species of galliform birds. |
2021-08-10 |
2023-08-13 |
Not clear |
| Felipe Cunha, Kelsey Racicot, Janae Nahirney, Courtney Heuston, Douglas R Wylie, Andrew N Iwaniu. Allometric Scaling Rules of the Cerebellum in Galliform Birds. Brain, behavior and evolution. vol 95. issue 2. 2021-08-10. PMID:32739912. |
both numbers and sizes of purkinje cells increased with cerebellar volume, but numbers of purkinje cells increased at a much faster rate than size. |
2021-08-10 |
2023-08-13 |
Not clear |
| Felipe Cunha, Kelsey Racicot, Janae Nahirney, Courtney Heuston, Douglas R Wylie, Andrew N Iwaniu. Allometric Scaling Rules of the Cerebellum in Galliform Birds. Brain, behavior and evolution. vol 95. issue 2. 2021-08-10. PMID:32739912. |
sizes and numbers of purkinje cells as well as numbers of granule cells were positively correlated with the degree of cerebellar foliation, but granule cell size decreased with higher degrees of foliation. |
2021-08-10 |
2023-08-13 |
Not clear |
| Ryaan El-Andari, Felipe Cunha, Barbara Tschirren, Andrew N Iwaniu. Selection for Divergent Reproductive Investment Affects Neuron Size and Foliation in the Cerebellum. Brain, behavior and evolution. vol 95. issue 2. 2021-08-10. PMID:32784306. |
the number of purkinje cells also significantly and positively co-varied with total cerebellar volume and the molecular layer, but not the granule cell layer or white matter volumes. |
2021-08-10 |
2023-08-13 |
Not clear |
| Lilla E Szabó, G Mark Marcello, Miklós Süth, Péter Sótonyi, Bence Rác. Distribution of cortactin in cerebellar Purkinje cell spines. Scientific reports. vol 11. issue 1. 2021-08-09. PMID:33446758. |
spines of cerebellar purkinje cells (pcs) are plastic, but they differ from forebrain spines in a number of important respects, and the mechanisms of spine plasticity differ between forebrain and cerebellum. |
2021-08-09 |
2023-08-13 |
Not clear |
| Yuki Yamazaki, Jun Nagai, Satoshi Akinaga, Yumeno Koga, Masaya Hasegawa, Miyuki Takahashi, Naoya Yamashita, Papachan Kolattukudy, Yoshio Goshima, Toshio Ohshim. Phosphorylation of CRMP2 is required for migration and positioning of Purkinje cells: Redundant roles of CRMP1 and CRMP4. Brain research. vol 1736. 2021-08-02. PMID:32156571. |
proper migration and positioning of purkinje cells are important for formation of the developing cerebellum. |
2021-08-02 |
2023-08-13 |
mouse |
| Yuki Yamazaki, Jun Nagai, Satoshi Akinaga, Yumeno Koga, Masaya Hasegawa, Miyuki Takahashi, Naoya Yamashita, Papachan Kolattukudy, Yoshio Goshima, Toshio Ohshim. Phosphorylation of CRMP2 is required for migration and positioning of Purkinje cells: Redundant roles of CRMP1 and CRMP4. Brain research. vol 1736. 2021-08-02. PMID:32156571. |
we hypothesized compensatory redundant functions of the other crmps, and analyzed the migration and positioning of purkinje cells in the cerebellum in every combination of crmp1 knockout (ko), crmp2 ki/ki, and crmp4 ko mice. |
2021-08-02 |
2023-08-13 |
mouse |
| Yuki Yamazaki, Jun Nagai, Satoshi Akinaga, Yumeno Koga, Masaya Hasegawa, Miyuki Takahashi, Naoya Yamashita, Papachan Kolattukudy, Yoshio Goshima, Toshio Ohshim. Phosphorylation of CRMP2 is required for migration and positioning of Purkinje cells: Redundant roles of CRMP1 and CRMP4. Brain research. vol 1736. 2021-08-02. PMID:32156571. |
these results suggest the importance of both, phosphorylation of crmp2 by cdk5 and the redundant functions of crmp1 and crmp4 in proper migration and positioning of purkinje cells in developing cerebellum. |
2021-08-02 |
2023-08-13 |
mouse |
| Carrie Sheeler, Juao-Guilherme Rosa, Ella Borgenheimer, Aaron Mellesmoen, Orion Rainwater, Marija Cvetanovi. Post-symptomatic Delivery of Brain-Derived Neurotrophic Factor (BDNF) Ameliorates Spinocerebellar Ataxia Type 1 (SCA1) Pathogenesis. Cerebellum (London, England). vol 20. issue 3. 2021-07-31. PMID:33394333. |
we have found that post-symptomatic delivery of extrinsic bdnf ameliorated motor deficits and cerebellar pathology (i.e., dendritic atrophy of purkinje cells, and astrogliosis) indicating therapeutic potential of bdnf even after the onset of symptoms in sca1. |
2021-07-31 |
2023-08-13 |
mouse |
| Miwako Yamasaki, Atsu Aiba, Masanobu Kano, Masahiko Watanab. mGluR1 signaling in cerebellar Purkinje cells: Subcellular organization and involvement in cerebellar function and disease. Neuropharmacology. vol 194. 2021-07-28. PMID:34089728. |
mglur1 signaling in cerebellar purkinje cells: subcellular organization and involvement in cerebellar function and disease. |
2021-07-28 |
2023-08-13 |
mouse |
| Miwako Yamasaki, Atsu Aiba, Masanobu Kano, Masahiko Watanab. mGluR1 signaling in cerebellar Purkinje cells: Subcellular organization and involvement in cerebellar function and disease. Neuropharmacology. vol 194. 2021-07-28. PMID:34089728. |
purkinje cells are the sole output neurons in the cerebellar cortex and therefore play crucial roles in the diverse functions of the cerebellum. |
2021-07-28 |
2023-08-13 |
mouse |
| Miwako Yamasaki, Atsu Aiba, Masanobu Kano, Masahiko Watanab. mGluR1 signaling in cerebellar Purkinje cells: Subcellular organization and involvement in cerebellar function and disease. Neuropharmacology. vol 194. 2021-07-28. PMID:34089728. |
we also describe emerging evidence that altered mglur1 signaling in purkinje cells underlies cerebellar dysfunction in ataxias of human patients and mouse models. |
2021-07-28 |
2023-08-13 |
mouse |
| Saeed Farjami, Ryan P D Alexander, Derek Bowie, Anmar Khadr. Switching in Cerebellar Stellate Cell Excitability in Response to a Pair of Inhibitory/Excitatory Presynaptic Inputs: A Dynamical System Perspective. Neural computation. vol 32. issue 3. 2021-07-23. PMID:31951795. |
cerebellar stellate cells form inhibitory synapses with purkinje cells, the sole output of the cerebellum. |
2021-07-23 |
2023-08-13 |
Not clear |
| Akshay Markanday, Joachim Bellet, Marie E Bellet, Junya Inoue, Ziad M Hafed, Peter Thie. Using deep neural networks to detect complex spikes of cerebellar Purkinje cells. Journal of neurophysiology. vol 123. issue 6. 2021-07-19. PMID:32374226. |
one of the most powerful excitatory synapses in the brain is formed by cerebellar climbing fibers, originating from neurons in the inferior olive, that wrap around the proximal dendrites of cerebellar purkinje cells. |
2021-07-19 |
2023-08-13 |
human |
| Jian Zhu, Han-Tsing Wang, Yu-Rong Chen, Ling-Ya Yan, Ying-Ying Han, Ling-Yan Liu, Ying Cao, Zhi-Zhi Liu, Hong A X. The Joubert Syndrome Gene arl13b is Critical for Early Cerebellar Development in Zebrafish. Neuroscience bulletin. vol 36. issue 9. 2021-07-19. PMID:32812127. |
the expression of atoh1 and ptf1, proneural genes of granule and purkinje cells, respectively, were selectively down-regulated along the dorsal midline of the cerebellum. |
2021-07-19 |
2023-08-13 |
zebrafish |
| Elisabeth H L Rusholt, Lisette Salvesen, Tomasz Brudek, Betel Tesfay, Bente Pakkenberg, Mikkel V Olese. Pathological changes in the cerebellum of patients with multiple system atrophy and Parkinson's disease-a stereological study. Brain pathology (Zurich, Switzerland). vol 30. issue 3. 2021-07-08. PMID:31769073. |
in the present study, we performed a stereological comparison of cerebellar volumes, granule and purkinje cells in 13 patients diagnosed with msa [8 msa-p (striatonigral subtype) and 5 msa-c (olivopontocerebellar subtype)], 12 pd patients, and 15 age-matched control subjects. |
2021-07-08 |
2023-08-13 |
human |
| Sabine C Winkler, Etsuko Shimobayashi, Josef P Kapfhamme. PKCγ-Mediated Phosphorylation of CRMP2 Regulates Dendritic Outgrowth in Cerebellar Purkinje Cells. Molecular neurobiology. vol 57. issue 12. 2021-07-01. PMID:32860158. |
we show that in cerebellar slice cultures from pkcγ(s361g)-mice, phosphorylation of crmp2 at the known pkc target site thr555 is increased in purkinje cells confirming phosphorylation of crmp2 by pkcγ. |
2021-07-01 |
2023-08-13 |
mouse |