| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Insung Kang, Je Min Yoo, Donghoon Kim, Juhee Kim, Myung Keun Cho, Seung-Eun Lee, Dong Jin Kim, Byung-Chul Lee, Jin Young Lee, Jae-Jun Kim, Nari Shin, Soon Won Choi, Young-Ho Lee, Han Seok Ko, Seokmin Shin, Byung Hee Hong, Kyung-Sun Kan. Graphene Quantum Dots Alleviate Impaired Functions in Niemann-Pick Disease Type C in Vivo. Nano letters. vol 21. issue 5. 2021-06-24. PMID:33472003. |
more importantly, the injection of gqds inhibits the loss of purkinje cells in the cerebellum while also demonstrating reduced activation of microglia. |
2021-06-24 |
2023-08-13 |
Not clear |
| Daisuke Koga, Satoshi Kusumi, Tsuyoshi Watanab. Optimizing the reaction temperature to facilitate an efficient osmium maceration procedure. Biomedical research (Tokyo, Japan). vol 41. issue 4. 2021-06-23. PMID:32801265. |
this rapid osmium maceration procedure was used successfully to observe the 3d ultrastructure of purkinje cells in the cerebellum and proximal convoluted tubule cells in the kidney. |
2021-06-23 |
2023-08-13 |
Not clear |
| Yueh-Chi Wu, Elan D Louis, John Gionco, Ming-Kai Pan, Phyllis L Faust, Sheng-Han Ku. Increased Climbing Fiber Lateral Crossings on Purkinje Cell Dendrites in the Cerebellar Hemisphere in Essential Tremor. Movement disorders : official journal of the Movement Disorder Society. vol 36. issue 6. 2021-06-23. PMID:33497495. |
climbing fibers (cfs) innervate purkinje cells (pcs) with 1:1 relationship to ensure proper cerebellar function. |
2021-06-23 |
2023-08-13 |
Not clear |
| Christian Hanse. Part II. J. C. Eccles, R. Llinas and K. Sasaki, The Excitatory Synaptic Action of Climbing Fibres on the Purkinje Cells of the Cerebellum, J Physiol, 182: 268-296, 1966: the Rise of the Complex Spike. Cerebellum (London, England). vol 20. issue 3. 2021-06-22. PMID:33638794. |
j. c. eccles, r. llinas and k. sasaki, the excitatory synaptic action of climbing fibres on the purkinje cells of the cerebellum, j physiol, 182: 268-296, 1966: the rise of the complex spike. |
2021-06-22 |
2023-08-13 |
Not clear |
| Ahmed I Abo-Ahmed, Mahmoud Abdelghaffar Ema. Expression of vesicular glutamate transporter 2 and 3 and glutamate receptor 1 and 2 mRNAs in the retina of adult laughing doves (Streptopelia senegalensis): An in situ hybridization study. Acta histochemica. vol 122. issue 6. 2021-06-21. PMID:32778249. |
vglut2 mrna was highly expressed only in the granular layer of the cerebellum while vglut3 mrna was weakly expressed only in the purkinje cells layer. |
2021-06-21 |
2023-08-13 |
Not clear |
| Ahmed I Abo-Ahmed, Mahmoud Abdelghaffar Ema. Expression of vesicular glutamate transporter 2 and 3 and glutamate receptor 1 and 2 mRNAs in the retina of adult laughing doves (Streptopelia senegalensis): An in situ hybridization study. Acta histochemica. vol 122. issue 6. 2021-06-21. PMID:32778249. |
glur1 mrna was intensely expressed in the purkinje cells layer while glur2 mrna signals were highly detectable in both granular and purkinje cells layers of the cerebellum. |
2021-06-21 |
2023-08-13 |
Not clear |
| Mario Manto, Lazaros C Triarho. Part I: The Complex Spikes as One of the Cerebellar Secrets. Cerebellum (London, England). vol 20. issue 3. 2021-06-21. PMID:33638793. |
this cerebellar classic is devoted to the pioneering work of eccles, llinás, and sasaki on complex spikes using intracellular recordings from purkinje neurons. |
2021-06-21 |
2023-08-13 |
Not clear |
| Ryosuke Tsumagari, Sho Kakizawa, Sakiko Kikunaga, Yoshitaka Fujihara, Shuji Ueda, Minoru Yamanoue, Naoaki Saito, Masahito Ikawa, Yasuhito Shira. DGKγ Knock-Out Mice Show Impairments in Cerebellar Motor Coordination, LTD, and the Dendritic Development of Purkinje Cells through the Activation of PKCγ. eNeuro. vol 7. issue 2. 2021-06-18. PMID:32033984. |
dgkγ knock-out mice show impairments in cerebellar motor coordination, ltd, and the dendritic development of purkinje cells through the activation of pkcγ. |
2021-06-18 |
2023-08-13 |
mouse |
| Ryosuke Tsumagari, Sho Kakizawa, Sakiko Kikunaga, Yoshitaka Fujihara, Shuji Ueda, Minoru Yamanoue, Naoaki Saito, Masahito Ikawa, Yasuhito Shira. DGKγ Knock-Out Mice Show Impairments in Cerebellar Motor Coordination, LTD, and the Dendritic Development of Purkinje Cells through the Activation of PKCγ. eNeuro. vol 7. issue 2. 2021-06-18. PMID:32033984. |
in dgkγ ko mice, cerebellar motor coordination and long-term depression (ltd) were impaired, and the dendrites of purkinje cells from dgkγ ko mice were significantly retracted. |
2021-06-18 |
2023-08-13 |
mouse |
| Cristián Gutiérrez-Ibáñez, Max R Dannish, Tobias Kohl, Lutz Kettler, Catherine E Carr, Ryan K Tisdale, Andrew N Iwaniuk, Harald Luksch, Douglas R Wyli. Zebrin Expression in the Cerebellum of Two Crocodilian Species. Brain, behavior and evolution. vol 95. issue 1. 2021-06-15. PMID:32155640. |
orthogonal to the lobules, the cerebellum is comprised of sagittal zones that are revealed in the pattern of afferent inputs, the projection patterns of purkinje cells, and purkinje cell response properties, among other features. |
2021-06-15 |
2023-08-13 |
Not clear |
| Cristián Gutiérrez-Ibáñez, Max R Dannish, Tobias Kohl, Lutz Kettler, Catherine E Carr, Ryan K Tisdale, Andrew N Iwaniuk, Harald Luksch, Douglas R Wyli. Zebrin Expression in the Cerebellum of Two Crocodilian Species. Brain, behavior and evolution. vol 95. issue 1. 2021-06-15. PMID:32155640. |
aldolase c, also known as zebrin ii (zii), is a glycolytic enzyme expressed in the cerebellar purkinje cells of the vertebrate cerebellum. |
2021-06-15 |
2023-08-13 |
Not clear |
| Cristián Gutiérrez-Ibáñez, Max R Dannish, Tobias Kohl, Lutz Kettler, Catherine E Carr, Ryan K Tisdale, Andrew N Iwaniuk, Harald Luksch, Douglas R Wyli. Zebrin Expression in the Cerebellum of Two Crocodilian Species. Brain, behavior and evolution. vol 95. issue 1. 2021-06-15. PMID:32155640. |
contrary to our prediction, all purkinje cells in the crocodilian cerebellum had a generally homogenous expression of zii (zii+) rather than clear zii+/- stripes. |
2021-06-15 |
2023-08-13 |
Not clear |
| Taro Ishiguro, Yoshitaka Nagai, Kinya Ishikaw. Insight Into Spinocerebellar Ataxia Type 31 (SCA31) From Frontiers in neuroscience. vol 15. 2021-06-12. PMID:34113230. |
insight into spinocerebellar ataxia type 31 (sca31) from spinocerebellar ataxia type 31 (sca31) is a progressive neurodegenerative disease characterized by degeneration of purkinje cells in the cerebellum. |
2021-06-12 |
2023-08-13 |
Not clear |
| Etsuko Shimobayashi, Josef P Kapfhamme. A New Mouse Model Related to SCA14 Carrying a Pseudosubstrate Domain Mutation in PKCγ Shows Perturbed Purkinje Cell Maturation and Ataxic Motor Behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 41. issue 9. 2021-06-11. PMID:33478986. |
spinocerebellar ataxias (scas) are diseases characterized by cerebellar atrophy and loss of purkinje neurons caused by mutations in diverse genes. |
2021-06-11 |
2023-08-13 |
mouse |
| Shaoxuan Chen, Kunkun Zhang, Boxin Zhang, Mengyun Jiang, Xue Zhang, Yi Guo, Yingying Yu, Tianyu Qin, Hongda Li, Qiang Chen, Zhiyu Cai, Site Luo, Yi Huang, Jin Hu, Wei M. Temporarily Epigenetic Repression in Bergmann Glia Regulates the Migration of Granule Cells. Advanced science (Weinheim, Baden-Wurttemberg, Germany). vol 8. issue 10. 2021-06-10. PMID:34026436. |
forming tight interaction with both purkinje and granule cells (gcs), bergmann glia (bg) are essential for cerebellar morphogenesis and neuronal homeostasis. |
2021-06-10 |
2023-08-13 |
Not clear |
| Lisanne J Van't Sant, Joshua J White, Jan H J Hoeijmakers, Wilbert P Vermeij, Dick Jaarsm. In vivo 5-ethynyluridine (EU) labelling detects reduced transcription in Purkinje cell degeneration mouse mutants, but can itself induce neurodegeneration. Acta neuropathologica communications. vol 9. issue 1. 2021-06-07. PMID:34020718. |
we show that injection of eu directly into the cerebellum results in reproducible labelling of newly transcribed rna in cerebellar neurons and glia, with cell type-specific differences in relative labelling intensities, such as purkinje cells exhibiting the highest levels. |
2021-06-07 |
2023-08-13 |
mouse |
| Fan Zhang, Cheng-Kun Deng, Yong-Jie Huang, Yi-He Miao, Yao-Yi Wang, Ying Zhang, Zhong-Yi Qian, Wei-Quan Zhang, Rui-Dong Zhou, Bao Lei, Xin Shen, Xing-Yan Wu, Ge Cui, Jing-Ling Song, Zhi-Hao Mu, Ying-Ying Zo. Early Intervention of Gastrodin Improved Motor Learning in Diabetic Rats Through Ameliorating Vascular Dysfunction. Neurochemical research. vol 45. issue 8. 2021-06-03. PMID:32415405. |
our results have shown that motor learning was impaired in diabetic rats, coupled with damaged purkinje cells and decreased capillary density in the cerebellum. |
2021-06-03 |
2023-08-13 |
rat |
| Norhan Elshony, Atef M K Nassar, Yasser S El-Sayed, Dalia Samak, Ahmed Noreldin, Lamiaa Wasef, Hamida Saleh, Yaser H A Elewa, Shereen E Tawfeek, Abdullah A Saati, Gaber El-Saber Batiha, Michał Tomczyk, Masakazu Umezawa, Hazem M Shahee. Ameliorative Role of Cerium Oxide Nanoparticles Against Fipronil Impact on Brain Function, Oxidative Stress, and Apoptotic Cascades in Albino Rats. Frontiers in neuroscience. vol 15. 2021-06-01. PMID:34054412. |
immunohistochemical examination of brain tissues of rats-treated with fip showed abundant ionized calcium-binding adaptor molecule 1 (iba-1) microglia and caspase-3 and apoptotic cells with nearly negative calbindin and synaptophysin reaction, which were countered by fip + cenps treatment that revealed a critical decrease in caspase-3, iba-1 reaction with a strong calbindin positive reaction in most of the purkinje cells and strong synaptophysin reaction in the cerebrum and cerebellum tissues. |
2021-06-01 |
2023-08-13 |
rat |
| Yi-Mei Yang, Jason Arsenault, Alaji Bah, Mickael Krzeminski, Adam Fekete, Owen Y Chao, Laura K Pacey, Alex Wang, Julie Forman-Kay, David R Hampson, Lu-Yang Wan. Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain. Molecular psychiatry. vol 25. issue 9. 2021-05-14. PMID:30224722. |
here, we find that excessive gaba release from basket cells (bcs) attenuates the firing frequency of purkinje neurons (pns) in the cerebellum of fragile x mental retardation 1 (fmr1) knockout (ko) mice, a model of fragile x syndrome (fxs) with abrogated expression of the fragile x mental retardation protein (fmrp). |
2021-05-14 |
2023-08-13 |
mouse |
| Hiroyuki Yasui, Yasunori Matsuzaki, Ayumu Konno, Hirokazu Hira. Global Knockdown of Retinoid-related Orphan Receptor α in Mature Purkinje Cells Reveals Aberrant Cerebellar Phenotypes of Spinocerebellar Ataxia. Neuroscience. vol 462. 2021-05-14. PMID:32278059. |
global knockdown of retinoid-related orphan receptor α in mature purkinje cells reveals aberrant cerebellar phenotypes of spinocerebellar ataxia. |
2021-05-14 |
2023-08-13 |
mouse |