| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Min Joung Kim, Jun Hwi Cho, Jeong-Hwi Cho, Joon Ha Park, Ji Hyeon Ahn, Hyun-Jin Tae, Geum-Sil Cho, Bing Chun Yan, In Koo Hwang, Choong Hyun Lee, Eun Joo Bae, Moo-Ho Won, Jae-Chul Le. Impact of hyperthermia before and during ischemia-reperfusion on neuronal damage and gliosis in the gerbil hippocampus induced by transient cerebral ischemia. Journal of the neurological sciences. vol 348. issue 1-2. 2016-04-04. PMID:25434714. |
gfap-positive astrocytes and iba-1-positive microglia in the ischemic hippocampus were activated much earlier and much more accelerated in the hyperthermia+ischemia groups than those in the normothermia+ischemia groups. |
2016-04-04 |
2023-08-13 |
Not clear |
| Felipe V Gomes, Ricardo Llorente, Elaine A Del Bel, Maria-Paz Viveros, Meritxell López-Gallardo, Francisco S Guimarãe. Decreased glial reactivity could be involved in the antipsychotic-like effect of cannabidiol. Schizophrenia research. vol 164. issue 1-3. 2016-03-28. PMID:25680767. |
we also evaluated changes in neun (a neuronal marker), iba-1 (a microglia marker) and gfap (an astrocyte marker) expression in the medial prefrontal cortex (mpfc), dorsal striatum, nucleus accumbens core and shell, and dorsal hippocampus by immunohistochemistry. |
2016-03-28 |
2023-08-13 |
Not clear |
| Felipe V Gomes, Ricardo Llorente, Elaine A Del Bel, Maria-Paz Viveros, Meritxell López-Gallardo, Francisco S Guimarãe. Decreased glial reactivity could be involved in the antipsychotic-like effect of cannabidiol. Schizophrenia research. vol 164. issue 1-3. 2016-03-28. PMID:25680767. |
it also increased the number of gfap-positive astrocytes in the mpfc and the percentage of iba-1-positive microglia cells with a reactive phenotype in the mpfc and dorsal hippocampus without changing the number of iba-1-positive cells. |
2016-03-28 |
2023-08-13 |
Not clear |
| Hanadie Yousef, Michael J Conboy, Adam Morgenthaler, Christina Schlesinger, Lukasz Bugaj, Preeti Paliwal, Christopher Greer, Irina M Conboy, David Schaffe. Systemic attenuation of the TGF-β pathway by a single drug simultaneously rejuvenates hippocampal neurogenesis and myogenesis in the same old mammal. Oncotarget. vol 6. issue 14. 2016-03-21. PMID:26003168. |
at the levels of cellular mechanism, our results establish that the age-specific increase in tgf-β1 in the stem cell niches of aged hippocampus involves microglia and that such an increase is pro-inflammatory both in brain and muscle, as assayed by the elevated expression of β2 microglobulin (b2m), a component of mhc class i molecules. |
2016-03-21 |
2023-08-13 |
mouse |
| Kaoru Sat. Effects of Microglia on Neurogenesis. Glia. vol 63. issue 8. 2016-03-14. PMID:26010551. |
this review summarizes and organizes the literature concerning the effects of microglia on neurogenesis, particularly focusing on the subgranular zone (sgz) of the hippocampus and subventricular zone (svz) of the lateral ventricles, in which the neurogenic potential is progressively restricted during the life of the organism. |
2016-03-14 |
2023-08-13 |
Not clear |
| Ana Ca Oliveira, Maria Cs Pereira, Luana N da Silva Santana, Rafael M Fernandes, Francisco B Teixeira, Gedeão B Oliveira, Luanna Mp Fernandes, Enéas A Fontes-Júnior, Rui D Prediger, Maria E Crespo-López, Walace Gomes-Leal, Rafael R Lima, Cristiane do Socorro Ferraz Mai. Chronic ethanol exposure during adolescence through early adulthood in female rats induces emotional and memory deficits associated with morphological and molecular alterations in hippocampus. Journal of psychopharmacology (Oxford, England). vol 29. issue 6. 2016-02-22. PMID:25922423. |
these neurobehavioral deficits induced by ethanol exposure during adolescence through early adulthood were accompanied by the reduction of hippocampal formation volume as well as the loss of neurons, astrocytes and microglia cells in the hippocampus. |
2016-02-22 |
2023-08-13 |
rat |
| Maheedhar Kodali, Vipan K Parihar, Bharathi Hattiangady, Vikas Mishra, Bing Shuai, Ashok K Shett. Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature, and reduced glial activation. Scientific reports. vol 5. 2016-02-19. PMID:25627672. |
greatly waned neurogenesis, diminished microvasculature, astrocyte hypertrophy and activated microglia are among the most conspicuous structural changes in the aged hippocampus. |
2016-02-19 |
2023-08-13 |
rat |
| Birte A Igelhorst, Vanessa Niederkinkhaus, Claudia Karus, Maren D Lange, Irmgard D Dietze. Regulation of neuronal excitability by release of proteins from glial cells. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 370. issue 1672. 2016-02-16. PMID:26009773. |
as a second example, we show that the presence of microglia in hippocampal cultures can upregulate na(+) current density. |
2016-02-16 |
2023-08-13 |
Not clear |
| Birte A Igelhorst, Vanessa Niederkinkhaus, Claudia Karus, Maren D Lange, Irmgard D Dietze. Regulation of neuronal excitability by release of proteins from glial cells. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 370. issue 1672. 2016-02-16. PMID:26009773. |
comparable effects are induced by the exposure of neuron-enriched hippocampal cultures to tumour necrosis factor-α, which is released from stimulated microglia. |
2016-02-16 |
2023-08-13 |
Not clear |
| Taito Matsuda, Naoya Murao, Yuki Katano, Berry Juliandi, Jun Kohyama, Shizuo Akira, Taro Kawai, Kinichi Nakashim. TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus. Nature communications. vol 6. 2016-02-09. PMID:25751136. |
tlr9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus. |
2016-02-09 |
2023-08-13 |
mouse |
| Taito Matsuda, Naoya Murao, Yuki Katano, Berry Juliandi, Jun Kohyama, Shizuo Akira, Taro Kawai, Kinichi Nakashim. TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus. Nature communications. vol 6. 2016-02-09. PMID:25751136. |
here we show that microglia in the mouse hippocampus attenuate convulsive seizure-mediated aberrant neurogenesis through the activation of toll-like receptor 9 (tlr9), an innate immune sensor known to recognize microbial dna and trigger inflammatory responses. |
2016-02-09 |
2023-08-13 |
mouse |
| Mandy Busse, Stefan Busse, Aye Mu Myint, Tomasz Gos, Henrik Dobrowolny, Ulf J Müller, Bernhard Bogerts, Hans-Gert Bernstein, Johann Steine. Decreased quinolinic acid in the hippocampus of depressive patients: evidence for local anti-inflammatory and neuroprotective responses? European archives of psychiatry and clinical neuroscience. vol 265. issue 4. 2016-01-26. PMID:25409655. |
our data indicate that ud and bd are associated with a local reduction in quin-immunoreactive microglia in the hippocampus and underline the importance of the nmda-r signaling in depressive disorders. |
2016-01-26 |
2023-08-13 |
human |
| Kyung-Joo Seong, Hyun-Gwan Lee, Min Suk Kook, Hyun-Mi Ko, Ji-Yeon Jung, Won-Jae Ki. Epigallocatechin-3-gallate rescues LPS-impaired adult hippocampal neurogenesis through suppressing the TLR4-NF-κB signaling pathway in mice. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 20. issue 1. 2016-01-25. PMID:26807022. |
in addition, microglia were recruited with activatingtlr4-nf-κb signaling in the adult hippocampus by lps injection. |
2016-01-25 |
2023-08-13 |
mouse |
| Adam D Bachstetter, Linda J Van Eldik, Frederick A Schmitt, Janna H Neltner, Eseosa T Ighodaro, Scott J Webster, Ela Patel, Erin L Abner, Richard J Kryscio, Peter T Nelso. Disease-related microglia heterogeneity in the hippocampus of Alzheimer's disease, dementia with Lewy bodies, and hippocampal sclerosis of aging. Acta neuropathologica communications. vol 3. 2016-01-13. PMID:26001591. |
disease-related microglia heterogeneity in the hippocampus of alzheimer's disease, dementia with lewy bodies, and hippocampal sclerosis of aging. |
2016-01-13 |
2023-08-13 |
Not clear |
| Adam D Bachstetter, Linda J Van Eldik, Frederick A Schmitt, Janna H Neltner, Eseosa T Ighodaro, Scott J Webster, Ela Patel, Erin L Abner, Richard J Kryscio, Peter T Nelso. Disease-related microglia heterogeneity in the hippocampus of Alzheimer's disease, dementia with Lewy bodies, and hippocampal sclerosis of aging. Acta neuropathologica communications. vol 3. 2016-01-13. PMID:26001591. |
despite the extensive characterization of ad microglia, there are still many unanswered questions, and little is known about microglial morphology in other common forms of age-related dementia: particularly, dementia with lewy bodies (dlb) and hippocampal sclerosis of aging (hs-aging). |
2016-01-13 |
2023-08-13 |
Not clear |
| Adam D Bachstetter, Linda J Van Eldik, Frederick A Schmitt, Janna H Neltner, Eseosa T Ighodaro, Scott J Webster, Ela Patel, Erin L Abner, Richard J Kryscio, Peter T Nelso. Disease-related microglia heterogeneity in the hippocampus of Alzheimer's disease, dementia with Lewy bodies, and hippocampal sclerosis of aging. Acta neuropathologica communications. vol 3. 2016-01-13. PMID:26001591. |
in addition, no prior studies have attempted to compare and contrast the microglia morphology in the hippocampus of various neurodegenerative conditions. |
2016-01-13 |
2023-08-13 |
Not clear |
| Hong Sun, HaiQin Wu, Xin Yu, GuiLian Zhang, Ru Zhang, ShuQin Zhan, HuQing Wang, Ning Bu, XiaoLing Ma, YongNan L. Angiotensin II and its receptor in activated microglia enhanced neuronal loss and cognitive impairment following pilocarpine-induced status epilepticus. Molecular and cellular neurosciences. vol 65. 2016-01-11. PMID:25724109. |
these data suggest that losartan improves se-induced cognitive impairment by suppressing microglia mediated inflammatory responses and attenuating hippocampal neuronal loss. |
2016-01-11 |
2023-08-13 |
rat |
| Qiuying Zhao, Xiaofang Xie, Yonghua Fan, Jinqiang Zhang, Wei Jiang, Xiaohui Wu, Shuo Yan, Yubo Chen, Cheng Peng, Zili Yo. Phenotypic dysregulation of microglial activation in young offspring rats with maternal sleep deprivation-induced cognitive impairment. Scientific reports. vol 5. 2016-01-06. PMID:25830666. |
the results showed the number of iba1(+) microglia increased, that of hippocampal neurogenesis decreased, and the hippocampus-dependent spatial learning and memory were impaired in msd offspring. |
2016-01-06 |
2023-08-13 |
rat |
| Bethany L Peterson, Soonmi Won, Rastafa I Geddes, Iqbal Sayeed, Donald G Stei. Sex-related differences in effects of progesterone following neonatal hypoxic brain injury. Behavioural brain research. vol 286. 2016-01-04. PMID:25746450. |
progesterone-treated, hi-injured male rats had fewer activated microglia in the cortex and hippocampus compared to controls. |
2016-01-04 |
2023-08-13 |
rat |
| Catrinel Girbovan, Hélène Plamondo. Resveratrol downregulates type-1 glutamate transporter expression and microglia activation in the hippocampus following cerebral ischemia reperfusion in rats. Brain research. vol 1608. 2015-12-24. PMID:25727173. |
resveratrol downregulates type-1 glutamate transporter expression and microglia activation in the hippocampus following cerebral ischemia reperfusion in rats. |
2015-12-24 |
2023-08-13 |
rat |